Morphine combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neoplasm Malignant Other Serious 1/1/2000 47 Male 231 lb 1/4/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Skin Oedema Other Serious 1/1/2005 79 Male 1/13/2006 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/24/2005 71 Female 12/6/2005 Pharmacist United States
Primary
Concomitant
Skin Oedema Other Serious 1/1/2005 79 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 49 Female 2/28/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Death 94 Female 3/2/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2003 57 Male 5/9/2006 Australia
Primary
Concomitant
Treatment Noncompliance Other Serious 49 Female 132 lb 5/4/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Respiratory Rate Decreased Required Intervention 2/11/2005 88 Female 115 lb 5/16/2006 Pharmacist United States
Primary
Secondary
Prothrombin Time Prolonged Death 94 Female 5/26/2006 Other Health Professional United States
Primary
Concomitant
Unresponsive To Verbal Stimuli Life Threatening 4/28/2006 Female 105 lb 6/20/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 5/8/2006 83 Female 135 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Nausea 76 Female 124 lb 5/24/2006 Consumer United States
Primary
Concomitant
Respiratory Depression Other Serious 7/12/2006 Female 120 lb 8/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Life Threatening 5/21/2006 73 Female 207 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 7/24/2006 42 Male 183 lb 9/4/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 6/8/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 67 Male 132 lb 9/14/2006 Physician Canada
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/18/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/13/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 9/13/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/9/2006 73 Male Pharmacist United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Malnutrition Hospitalization 1/1/2006 77 Male 132 lb 11/28/2006 Physician Canada
Primary
Concomitant
Subclavian Vein Thrombosis Hospitalization 8/19/2005 Male 12/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/15/2006 49 Female 165 lb 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Splenic Infarction Required Intervention 4/19/2006 Male 12/15/2006 Pharmacist United States
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 77 Male 132 lb 12/22/2006 Physician Canada
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Vertebroplasty Other Serious 11/24/2006 78 Female 1/15/2007 Consumer Canada
Primary
Concomitant
Spinal Epidural Haemorrhage Other Serious 11/30/2006 80 Female 1/22/2007 Norway
Primary
Secondary
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/30/2006 80 Female 1/30/2007 Norway
Primary
Secondary
Urticaria Other Serious 9/6/2006 63 Female 134 lb 1/2/2007 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 12/14/2006 Male 150 lb 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 2/11/2007 25 Female 240 lb 2/22/2007 Pharmacist United States
Primary
Concomitant
Rash Generalised Other Serious 2/17/2007 25 Female 240 lb 2/21/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 1/1/2006 78 Female 3/14/2007 Consumer Canada
Primary
Concomitant
Delusion Of Replacement Death 77 Female 3/23/2007
Primary
Secondary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/1/2007 54 Female 3/26/2007 Physician Peru
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 3/9/2007 68 Male 161 lb 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Tremor 1/1/2006 43 Female 110 lb 1/23/2007 Consumer United States
Primary
Concomitant
Central Line Infection Hospitalization 3/2/2007 55 Female 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Cerebral Arteriosclerosis Hospitalization 3/9/2007 Male 161 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 3/1/2007 62 Male 186 lb 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 2/1/2007 25 Female 5/2/2007 Physician United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 2/1/2007 25 Female 5/8/2007 Physician United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 1/11/2007 65 Male 192 lb 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/24/2006 Male 439 lb 5/15/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 54 Female 6/25/2007 Physician Peru
Primary
Secondary
Concomitant
Cerebral Arteriosclerosis Hospitalization 3/9/2007 Male 161 lb 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 5/1/2007 80 Female 8/1/2007 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/22/2007 53 Female 174 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 6/5/2007 51 Female 280 lb 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Hostility Hospitalization 10/31/2007 Female 140 lb 11/16/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/2/2007 11/19/2007 Australia
Primary
Secondary
Concomitant
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 82 Female 12/6/2007
Primary
Secondary
Concomitant
Femoral Hernia Hospitalization 12/16/2003 Female 170 lb 12/10/2007 United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 11/18/2007 Male 231 lb 12/20/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 10/23/2007 8 Male 57 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Self-medication Hospitalization 7/24/2007 41 Female 139 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 11/14/2007 70 Female 146 lb 12/3/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Nausea Hospitalization 11/18/2007 Male 231 lb 2/15/2008 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/1/2007 50 Female 2/20/2008 Consumer Canada
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 2/8/2008 Male 181 lb 2/22/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/25/2007 46 Female 11/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Cerebral Haematoma Death 3/18/2008 55 Female 249 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Thrombosis Death 2/22/2008 85 Female 3/27/2008 United States
Primary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 4/2/2008 Consumer United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 68 Female 4/25/2008 Other Health Professional United States
Primary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 152 lb 5/2/2008 Consumer United States
Primary
Concomitant
Splenic Rupture Other Serious 2/12/2008 65 Female 159 lb 5/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2008 Female 98 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Vena Cava Injury Death 2/8/2008 Female 180 lb 6/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Pulmonary Embolism Death 1/14/1998 Female 7/7/2008 Physician Canada
Primary
Concomitant
Urinary Retention Hospitalization 5/9/2008 Female 185 lb 7/7/2008 Consumer United States
Primary
Concomitant
Rash Hospitalization 6/15/2008 63 Female 7/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 6/15/2008 63 Female 7/2/2008 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/8/2007 61 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Ulcer 6/15/2008 63 Female 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Compression Fracture Other Serious 1/1/2007 Female 150 lb 7/18/2008 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 75 Male 8/1/2008 Pharmacist Australia
Primary
Concomitant
Neutropenia Other Serious 5/19/2008 Female 8/13/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2008 Female 157 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 47 Female 8/20/2008 Canada
Primary
Secondary
Confusional State 6/30/2008 93 Female 128 lb 9/2/2008 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 7/28/2008 61 Female 9/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hallucination, Visual Hospitalization 8/19/2008 61 Male 386 lb 8/20/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased 47 Female 9/18/2008 Canada
Primary
Secondary
Vomiting Hospitalization 9/1/2008 Female 143 lb 9/30/2008 United States
Primary
Concomitant
Paraesthesia Hospitalization 10/11/2007 49 Female 12/10/2007 Physician United States
Primary
Concomitant
Renal Failure Other Serious 9/1/2008 Female 140 lb 10/3/2008 United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 63 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Haemorrhage Required Intervention 5/22/2008 Female 114 lb 6/24/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 4/10/2008 55 Male 351 lb 10/27/2008 Physician United States
Primary
Concomitant
Panniculitis Required Intervention 8/10/2008 41 Female 333 lb 8/28/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Death Death 1/29/2009 Female 145 lb 2/4/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Death Female 145 lb 2/19/2009 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/2/2009 Female 122 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/6/2009 Female 3/13/2009 Consumer United States
Primary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 3/9/2009 71 Female 3/13/2009 Consumer United States
Primary
Secondary
Concomitant
Vertebroplasty Other Serious 10/1/2006 Male 3/20/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Metastases To Liver Other Serious Female 145 lb 4/16/2009 Canada
Primary
Concomitant
Stem Cell Transplant Other Serious Male 4/22/2009 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 2/6/2009 Female 4/28/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 3/9/2009 46 Female 170 lb 4/3/2009 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/7/2009 66 Male 4/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 9/10/2006 80 Male 187 lb 5/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Gastric Disorder 3/17/2009 Male 5/27/2009 United States
Primary
Concomitant
Renal Failure Death 82 Male 6/10/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 7/1/2005 82 Male 6/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 82 Male 6/23/2009 United Kingdom
Primary
Concomitant
Renal Failure Death 82 Male 7/10/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 82 Male 7/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Death 82 Male 7/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data