Morphine combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Decomposition Other Serious 9/1/2003 49 Male 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Urea Urine Increased Other Serious 12/17/2005 76 Female 2/27/2006 Physician Netherlands
Primary
Secondary
Concomitant
Urine Output Decreased Life Threatening 3/27/2006 47 Female 134 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Death 10/7/2004 53 Male 142 lb 4/4/2006 Physician Canada
Primary
Concomitant
Sternal Fracture Other Serious 6/5/2005 57 Male 4/11/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/13/2006 57 Male 5/1/2006 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 3/27/2006 68 Male 4/25/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 4/29/2005 70 Male 6/8/2006 Physician Switzerland
Primary
Concomitant
Pleural Effusion Other Serious 1/1/2006 Male 187 lb 6/12/2006 Physician Switzerland
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Self-injurious Ideation Hospitalization 7/29/2005 73 Female 126 lb 6/21/2006 Physician Italy
Primary
Concomitant
Mantle Cell Lymphoma Other Serious 1/1/2006 Male 187 lb 6/28/2006 Physician Switzerland
Primary
Concomitant
Urine Output Decreased Life Threatening 3/27/2006 47 Female 134 lb 5/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 1/6/2006 68 Female 148 lb 7/18/2006 Physician Australia
Primary
Concomitant
Diarrhoea Hospitalization 6/30/2006 74 Male 190 lb 7/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 1/6/2006 68 Female 148 lb 8/4/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2003 57 Male 8/16/2006 Physician Canada
Primary
Concomitant
Infection Hospitalization 8/21/2006 62 Male 136 lb 8/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/22/2006 69 Male 200 lb 9/7/2006 Physician United States
Primary
Concomitant
Postictal State Other Serious 9/5/2006 68 Female 114 lb 9/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/21/2006 62 Male 136 lb 9/14/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/2/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Other Serious 9/29/2006 Female 56 lb 10/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/21/2006 62 Male 136 lb 10/24/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/26/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 11/2/2006 77 Female 85 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 7/23/2006 52 Male 181 lb 11/3/2006 Physician Italy
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 12/8/2006 Female 118 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/15/2006 49 Female 165 lb 12/8/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 12/15/2006 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Life Threatening 12/4/2006 59 Unknown 12/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Acute Hepatic Failure Life Threatening 11/30/2006 69 Male 212 lb 12/18/2006 Physician Germany
Primary
Concomitant
Herpes Virus Infection Life Threatening 12/4/2006 59 12/28/2006 Physician Netherlands
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 11/30/2006 69 Male 212 lb 12/29/2006 Physician Germany
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 12/4/2006 59 1/15/2007 Physician Netherlands
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/25/2007 53 Male 2/16/2007 Physician Japan
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 2/15/2007 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/30/2006 69 Male 212 lb 2/13/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/17/2007 53 Male 2/23/2007 Physician Japan
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 3/2/2007 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/17/2007 53 Male 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 2/24/2007 67 Female 132 lb 3/12/2007 Physician Canada
Primary
Concomitant
Neoplasm Malignant Disability 12/28/2006 65 Female 3/8/2007 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 2/24/2007 67 Female 132 lb 3/22/2007 Physician Canada
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 1/17/2007 53 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/24/2006 54 Unknown 4/16/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/24/2006 54 Female 5/2/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/24/2006 54 Female 5/8/2007 Physician Netherlands
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 6/15/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/8/2007 50 Female 137 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/29/2007 69 Female 150 lb 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/25/2003 9/28/2007 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 5/29/2007 69 Female 150 lb 9/28/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/25/2003 10/10/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 11/1/2003 55 Male 261 lb 10/11/2007 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 5/29/2007 69 Female 150 lb 10/9/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 9/17/2007 61 11/23/2007 Physician Netherlands
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/25/2007 80 Female 75 lb 12/4/2007 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/30/2007 76 Female 119 lb 12/6/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/1/2003 55 Male 261 lb 12/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/30/2007 Female 95 lb 1/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/27/2006 59 Male 215 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/29/2007 62 Male 84 lb 2/11/2008 Physician Japan
Primary
Secondary
Concomitant
Headache 8/1/2007 58 Male 10/18/2007 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 4/30/2007 76 Female 119 lb 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 6/8/2007 50 Female 137 lb 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 4/30/2007 76 Female 119 lb 3/17/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 9/25/2007 80 Female 75 lb 4/10/2008 Physician Japan
Primary
Concomitant
Tinnitus Other Serious 4/7/2008 Male 165 lb 4/28/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Drainage Other Serious 6/1/2003 Male 261 lb 5/30/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/3/2006 59 Male 215 lb 5/30/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/3/2007 56 Female 110 lb 6/2/2008 Physician Japan
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 Male 182 lb 6/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2004 Female 180 lb 6/12/2008 United States
Primary
Secondary
Concomitant
Atrial Tachycardia Hospitalization 4/8/2008 59 Male 401 lb 6/11/2008 Physician Germany
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 6/26/2008 Physician Germany
Primary
Secondary
Concomitant
Sternal Fracture Other Serious 6/5/2005 57 Male 8/1/2008 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2004 Female 180 lb 8/12/2008 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Male 182 lb 8/13/2008 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 8/11/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/5/2007 54 Male 143 lb 8/12/2008 Physician France
Primary
Secondary
Leukocytoclastic Vasculitis Other Serious 9/18/2007 75 Female 106 lb 8/14/2008 Physician France
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Male 182 lb 8/27/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 10/29/2007 62 Male 84 lb 9/10/2008 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 11/26/2007 65 Male 161 lb 10/12/2008 Physician Japan
Primary
Secondary
Concomitant
Syringomyelia Other Serious 1/1/2008 61 Male 188 lb 10/20/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/31/2008 53 Female 229 lb 11/7/2008 Physician France
Primary
Secondary
Concomitant
Syringomyelia Other Serious 1/1/2008 61 Male 188 lb 11/12/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 10/28/2008 58 Male 192 lb 11/20/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 11/6/2008 46 Male 151 lb 11/19/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/31/2008 53 Female 229 lb 12/8/2008 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/28/2008 55 Male 213 lb 1/21/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/28/2008 55 Male 212 lb 1/26/2009 Physician United States
Primary
Secondary
Concomitant
Hallucination, Visual Hospitalization 10/9/2008 Male 1/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/31/2008 53 Female 229 lb 2/2/2009 Physician France
Primary
Secondary
Concomitant
Sudden Death Other Serious 11/8/2008 76 Female 154 lb 1/30/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/12/2009 Male 196 lb 2/5/2009 Physician Germany
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/12/2009 57 Male 196 lb 2/13/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 12/1/2008 74 Female 2/19/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Muscle Rigidity Other Serious 1/1/2009 2/23/2009 Consumer Japan
Primary
Concomitant
Vomiting Other Serious 2/1/2004 Female 180 lb 3/3/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/2/2009 45 Female 79 lb 3/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nocardiosis Hospitalization 10/28/2008 58 Male 192 lb 4/2/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Cardiotoxicity Hospitalization 4/8/2008 59 Male 401 lb 4/6/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/3/2007 56 Female 110 lb 4/8/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/9/2008 66 Female 139 lb 4/16/2009 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 12/4/2008 74 Female 4/23/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cholestasis Other Serious 62 Male 4/23/2009 Physician Greece
Primary
Concomitant
Respiratory Failure Other Serious 4/1/2009 73 Male 173 lb 5/6/2009 United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/4/2008 47 Male 165 lb 5/8/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/1/2009 73 Male 173 lb 5/22/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/20/2006 65 Female 84 lb 5/18/2009 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 60 Male 5/29/2009 Physician Greece
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/3/2007 56 Female 110 lb 6/10/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/9/2007 65 Female 139 lb 6/18/2009 Physician Japan
Primary
Secondary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/27/2006 59 Male 215 lb 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious 60 Male 6/25/2009 Physician Greece
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/31/2008 53 Female 229 lb 6/29/2009 Physician France
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 6/1/2009 52 Female 111 lb 7/9/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/20/2006 65 Female 84 lb 7/17/2009 Physician Japan
Primary
Concomitant
Mucosal Inflammation Hospitalization 6/1/2009 Male 8/6/2009 Consumer France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 6/14/2009 Male 8/10/2009 Other Health Professional France
Primary
Secondary
Septic Shock Other Serious 1/1/2009 Male 127 lb 8/31/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/28/2007 58 Male 141 lb 8/26/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 1/1/2009 Male 127 lb 9/16/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/2/2009 45 Female 79 lb 9/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/2/2009 45 Female 79 lb 9/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Female 240 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 9/28/2009 50 Male 260 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Death Death Female 240 lb 11/4/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 9/28/2009 50 Male 260 lb 10/29/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/29/2007 69 Female 150 lb 11/5/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/29/2007 57 Male 104 lb 11/17/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 9/16/2007 78 Female 95 lb 11/24/2009 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 9/16/2007 78 Female 95 lb 12/28/2009 Physician Japan
Primary
Secondary
Concomitant

Drug Data