Morphine combined with Temazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Required Intervention 6/28/2005 61 Male 179 lb 10/21/2005 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
Vomiting 6/28/2005 64 Female 148 lb 10/14/2005 United States
Primary
Concomitant
Vomiting Hospitalization 11/19/2005 50 Male 1/31/2006 United States
Primary
Concomitant
Overdose Death 59 3/9/2006 United States
Primary
Secondary
Sedation Hospitalization 6/16/2003 49 Female 231 lb 3/23/2006 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Death 12/1/2003 69 Female 214 lb 4/19/2006 Lawyer United States
Primary
Concomitant
Chest Pain Other Serious 4/25/2006 51 Male 135 lb 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 5/3/2006 61 Male 220 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/22/2005 87 Male 5/1/2006 Physician United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/25/2006 51 Male 135 lb 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Middle Insomnia 2/15/2006 51 Female 162 lb 4/3/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 12/22/2005 87 Male 5/26/2006 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2006 56 Male 180 lb 4/20/2006 United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 6/7/2006 United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 11/11/2005 0 Female 6/14/2006 Physician Netherlands
Primary
Concomitant
Post Procedural Complication Disability 5/12/2006 85 Female 112 lb 5/24/2006 United States
Primary
Concomitant
No Therapeutic Response Hospitalization 7/14/2005 29 Male 8/1/2006 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 8/31/2006 66 Male 138 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 4/1/2006 70 Male 4/3/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/9/2006 73 Male Pharmacist United States
Primary
Secondary
Concomitant
Death Death 10/6/2006 58 Female 141 lb 10/23/2006 Consumer United States
Primary
Concomitant
Drug Level Increased Death 31 11/6/2006 Physician United States
Primary
Secondary
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 42 Female 159 lb 11/16/2006
Primary
Secondary
Malignant Neoplasm Progression Death 58 Female 141 lb 11/17/2006 Physician United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2005 31 11/21/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Regimen Changed Life Threatening 9/1/2006 60 Male 164 lb 12/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 8/15/2006 Female 160 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Subclavian Vein Thrombosis Life Threatening 10/17/2006 43 Female 155 lb 10/22/2006 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 4/14/2006 Male 228 lb 1/18/2007 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 3/17/2006 73 Female 132 lb 1/17/2007 Consumer United States
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Somnolence Other Serious 1/17/2007 Male 195 lb 1/31/2007 Consumer United States
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 2/15/2007 Physician Australia
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 3/2/2007 Physician Australia
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 1/1/2003 62 Female 143 lb 10/22/2003 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 3/2/2007 74 Male 156 lb 3/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 8/9/2005 Female 4/19/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 3/23/2007 54 Female 119 lb 4/24/2007 Physician Netherlands
Primary
Secondary
Concomitant
Somnolence Other Serious 1/17/2007 Male 209 lb 4/30/2007 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 4/23/2007 Male 5/14/2007 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 5/8/2007 57 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Spleen Disorder Death 1/8/2004 79 Female 5/24/2007 Physician
Primary
Concomitant
Joint Effusion Hospitalization 7/8/2006 72 Male 6/19/2007 Other Health Professional Netherlands
Primary
Concomitant
Blood Creatinine Increased Other Serious 6/15/2007 Female 6/27/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 3/23/2007 54 Female 119 lb 7/5/2007 Physician Netherlands
Primary
Secondary
Concomitant
Haemoptysis Death 1/22/2007 Male 132 lb 7/11/2007 Other Health Professional Australia
Primary
Concomitant
Weight Decreased Hospitalization 3/23/2007 54 Female 119 lb 7/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Tachycardia Hospitalization 48 Female 8/24/2007
Primary
Secondary
Splenomegaly Death 3/12/2007 32 Male 165 lb 8/31/2007 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/16/2007 Male 9/27/2007 Australia
Primary
Concomitant
Wrong Drug Administered Required Intervention 9/3/2007 34 Female 165 lb 9/27/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 Female 10/31/2007 Pharmacist United States
Primary
Concomitant
Splenomegaly Other Serious 5/28/2007 17 Male 130 lb 10/25/2007 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 9/11/2007 84 Female 10/4/2007 Physician United States
Primary
Concomitant
Renal Tubular Acidosis Hospitalization 1/1/2007 Male 218 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 3/12/2007 32 Male 165 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/9/2007 Male 11/30/2007 Australia
Primary
Concomitant
Skin Cancer Other Serious 1/1/2007 Female 12/4/2007 Consumer Canada
Primary
Concomitant
Transplant Failure Hospitalization 12/13/2007 53 Male 225 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 1/1/2003 Female 130 lb 12/17/2007 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Hospitalization 1/1/2007 Male 218 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Hospitalization 1/1/2007 Male 218 lb 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/5/2007 Male 12/20/2007 Australia
Primary
Concomitant
Overdose Death 32 Female 1/10/2008 Physician United States
Primary
Secondary
Overdose Death 32 Female 1/14/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 32 Female 1/11/2008 Physician United States
Primary
Secondary
Death Death 1/1/2006 32 Female 1/17/2008 United States
Primary
Secondary
Squamous Cell Carcinoma Of Skin Hospitalization 1/1/2007 Female 1/18/2008 Consumer Canada
Primary
Concomitant
Respiratory Arrest Death 32 Female 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 32 Female 1/21/2008 Physician United States
Primary
Secondary
Renal Tubular Acidosis Hospitalization 9/27/2007 Male 218 lb 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/18/2008 Male 200 lb 2/12/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 32 Female 2/5/2008 Physician United States
Primary
Secondary
Suicide Attempt Other Serious 9/18/2003 46 Male 1/11/2008 United States
Primary
Concomitant
Ultrasound Abdomen Abnormal Hospitalization 7/17/2007 72 Male 174 lb 2/4/2008 Physician Australia
Primary
Secondary
Concomitant
Pain Hospitalization 5/1/2006 Male 140 lb 2/21/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 6/1/2007 57 Female 10/31/2007 Other Health Professional United States
Primary
Concomitant
Subclavian Vein Thrombosis Hospitalization 7/17/2007 72 Male 174 lb 2/4/2008 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/18/2008 Male 200 lb 2/27/2008 Consumer United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 2/7/2008 46 Female 2/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 48 Male 3/7/2008 Consumer Canada
Primary
Secondary
Concomitant
Respiratory Arrest Death 3/7/2008 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 32 Female 3/7/2008 Other Health Professional United States
Primary
Secondary
Treatment Noncompliance Other Serious 1/1/2004 Female 250 lb 3/20/2008 Consumer United States
Primary
Secondary
Concomitant
Off Label Use 12/16/2007 75 Male 230 lb 1/8/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/20/2008 Male 3/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Ocular Discomfort Other Serious 4/8/2007 38 Female 220 lb 4/1/2008 United States
Primary
Concomitant
Pain Hospitalization 5/1/2006 Male 140 lb 4/24/2008 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/29/2008 75 Male 165 lb 5/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 32 Female 5/19/2008 Physician United States
Primary
Secondary
Substance Abuse Other Serious 42 Female 6/6/2008 Physician Canada
Primary
Secondary
Renal Failure Acute Hospitalization 4/29/2008 75 Male 165 lb 5/29/2008 Physician United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Other Serious 49 Female 6/11/2008 Physician Canada
Primary
Secondary
Substance Abuse Other Serious 44 Male 6/16/2008 Physician Canada
Primary
Secondary
Urticaria Other Serious 3/14/2008 54 Female 159 lb 6/18/2008 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 5/1/2006 Male 140 lb 7/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 11/15/2006 51 Male 88 lb 7/8/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/16/2007 85 Female 7/28/2008 Pharmacist Netherlands
Primary
Concomitant
Urine Output Decreased Hospitalization 4/1/2008 75 Male 165 lb 8/6/2008 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2006 32 Female 8/18/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection 8/1/2007 Female 206 lb 9/13/2008 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2005 31 Female 9/19/2008 Physician United States
Primary
Secondary
Death Death 32 Female 10/30/2008 Physician United States
Primary
Secondary
Death Death 32 Female 10/31/2008 Physician United States
Primary
Secondary
Renal Impairment Hospitalization 2/16/2007 85 Female 11/17/2008 Pharmacist Netherlands
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 7/2/2008 62 Male 183 lb 7/17/2008 Pharmacist United States
Primary
Concomitant
Haemorrhage Required Intervention 5/22/2008 Female 114 lb 6/24/2008 United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/3/2008 67 Male 117 lb 11/17/2008 Consumer Canada
Primary
Secondary
Concomitant
Rash Erythematous Life Threatening 3/12/2008 Male 195 lb 11/21/2008 Pharmacist United States
Primary
Concomitant
Interacting
Pulmonary Embolism Life Threatening 5/4/2007 Female 11/24/2008 Physician United States
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/25/2008 Australia
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/4/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/2/2005 Male 12/5/2008
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 12/23/2008 Physician United States
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 33 Female 1/7/2009
Primary
Secondary
Intentional Drug Misuse Death 1/1/2007 49 Female 1/6/2009 United States
Primary
Secondary
Intentional Drug Misuse Death 49 Female 1/15/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 49 Female 1/26/2009 Physician United States
Primary
Secondary
Retroperitoneal Fibrosis Hospitalization 33 Female 1/28/2009 Physician New Zealand
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Completed Suicide Death 49 Female 3/9/2009 Physician United States
Primary
Secondary
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 3/5/2009 52 Male 206 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2007 71 Male 3/25/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Completed Suicide Death 4/14/2009 Other Health Professional United States
Primary
Secondary
Mental Impairment Death 2/1/2009 64 Male 4/16/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death 17 Female 4/17/2009 Consumer United States
Primary
Secondary
Drug Toxicity Death 1/1/2009 17 Female 4/21/2009 Physician United States
Primary
Secondary
Drug Toxicity Death 17 Female 4/20/2009 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 10/23/2006 40 Male 150 lb 5/18/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Headache Death Female 5/28/2009 Consumer United States
Primary
Secondary
Headache Death Female 5/29/2009 Consumer United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 4/7/2009 58 6/1/2009 Other Health Professional Australia
Primary
Secondary
Concomitant

Drug Data