Morphine combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Spinal Cord Infarction Other Serious 83 Male 1/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Cord Infarction Disability 83 Male 1/19/2006 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Required Intervention 12/13/2005 57 Male 148 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 1/3/2006 28 Female 4/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Somatosensory Evoked Potentials Abnormal Other Serious 7 Female 97 lb 5/20/2006 Australia
Primary
Concomitant
Wound Haemorrhage Other Serious 35 Female 116 lb 5/23/2006 Physician China
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/21/2006 43 Male 216 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 67 Female 123 lb 6/9/2006 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 67 Female 123 lb 7/12/2006 Other Health Professional Japan
Primary
Concomitant
Nerve Root Compression Other Serious 7 Female 97 lb 7/6/2006
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 44 Male 216 lb 7/14/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Tryptase Increased Other Serious Female 8/9/2006 Physician Ireland
Primary
Concomitant
Wound Secretion Other Serious 35 Female 116 lb 9/1/2006 Other Health Professional China
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Therapy Non-responder Required Intervention 43 Male 10/2/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization Male 10/19/2006
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Respiratory Depression Death 26 Female 112 lb 11/21/2006
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 1/1/2006 14 Male 12/6/2006 United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/8/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Ruptured Ectopic Pregnancy Hospitalization 11/26/2006 36 Female 153 lb 12/11/2006 United States
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 4 lb 1/8/2007 France
Primary
Secondary
Concomitant
Respiratory Depression Death 26 Female 112 lb 1/29/2007 Physician Germany
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Other Serious 4/27/2007 66 Female 5/17/2007 Physician Japan
Primary
Concomitant
Interacting
Drug Effect Prolonged Other Serious 4/27/2007 66 Female 115 lb 5/29/2007 Physician Japan
Primary
Concomitant
Interacting
Pulmonary Embolism Life Threatening 65 Male 6/27/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 65 Male 7/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2 Male 30 lb 7/13/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Miosis Hospitalization 9/27/2007 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 2 Female 32 lb 10/11/2007
Primary
Secondary
Concomitant
Stupor Hospitalization 1/1/2007 2 Male 30 lb 10/24/2007 United States
Primary
Concomitant
Respiratory Depression Life Threatening 11/1/2007
Primary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Life Threatening 53 Female 128 lb 11/19/2007
Primary
Secondary
Concomitant
Syncope Other Serious 14 Male 11/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 12/5/2007 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 10/2/2007 14 Female 77 lb 1/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Post Procedural Discharge Other Serious 9/26/2007 Female 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 2 Male 30 lb 2/11/2008 United States
Primary
Concomitant
Renal Impairment Other Serious 11 Female 66 lb 2/27/2008 Turkey
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11 Female 66 lb 2/29/2008 Turkey
Primary
Secondary
Concomitant
Sinus Arrest Required Intervention 1/9/2008 1 Female 21 lb 3/3/2008 Pharmacist Japan
Primary
Concomitant
Vomiting Other Serious 7/22/2005 65 Male 176 lb 3/1/2008 United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 58 Female 3/10/2008
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Male 3/13/2008 United Kingdom
Primary
Secondary
Concomitant
Therapy Cessation Hospitalization 62 Female 110 lb 4/15/2008 Physician France
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 33 Female 202 lb 4/30/2008 Physician United Kingdom
Primary
Concomitant
Migraine With Aura Other Serious 15 Male 152 lb 4/30/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Stress Other Serious 15 Male 152 lb 5/8/2008 Other Health Professional Australia
Primary
Concomitant
Haematocrit Decreased Hospitalization 7/20/2007 71 Male 5/20/2008 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 3 Male 37 lb 5/30/2008 Physician Canada
Primary
Concomitant
Migraine With Aura Hospitalization 15 Male 152 lb 6/6/2008 Australia
Primary
Secondary
Concomitant
Shock Other Serious 56 Female 192 lb 6/16/2008 Other Health Professional Portugal
Primary
Concomitant
Stress Cardiomyopathy Other Serious 31 Female 6/23/2008 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 3 Male 37 lb 7/17/2008
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/8/2007 14 Male 198 lb 8/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 7/22/2008 65 Male 176 lb 8/13/2008 United Kingdom
Primary
Concomitant
Interacting
Drug Ineffective Other Serious 31 Female 8/29/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 31 Female 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 9/5/2008
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 31 Female 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 9/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 30 Female 159 lb 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Hospitalization 3/6/2008 Female 11/14/2008 Physician France
Primary
Concomitant
Urticaria Hospitalization 3/6/2008 77 Female 11/26/2008 Physician France
Primary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/25/2008 79 Male 134 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 4 Male 37 lb 11/26/2008 Canada
Primary
Concomitant
Stillbirth Other Serious 20 Female 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Other Serious 3/3/2009 Male 130 lb 3/11/2009 Thailand
Primary
Concomitant
Hypotension Other Serious 3/3/2009 Male 130 lb 3/25/2009 Thailand
Primary
Concomitant
Hypotension Other Serious 3/3/2009 Male 130 lb 4/10/2009 Thailand
Primary
Concomitant
Respiratory Acidosis Other Serious 60 Male 4/13/2009
Primary
Secondary
Pulmonary Oedema Other Serious 11/8/2001 8 Male 82 lb 7/2/2009 Physician United Kingdom
Primary
Concomitant
Upper Airway Obstruction Death 12/16/2008 82 Male 6/30/2009 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Acidosis Other Serious 3/23/2007 60 Male 7/23/2009
Primary
Secondary
Upper Airway Obstruction Death 12/16/2008 82 Male 8/26/2009 Pharmacist United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 65 Male 8/26/2009 United Kingdom
Primary
Concomitant
Pancreatitis Other Serious Female 9/2/2009 Other Health Professional Australia
Primary
Concomitant
Pancreatitis Other Serious Female 10/12/2009 Physician Australia
Primary
Concomitant
Tachycardia Life Threatening 8/7/2009 43 Female 10/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 60 Female 198 lb 12/4/2009 Other Health Professional Belgium
Primary
Concomitant
Syncope Hospitalization 31 Female 12/3/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 59 Female 12/18/2009 Physician New Zealand
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 65 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 35 Female 115 lb 1/21/2010
Primary
Secondary
Concomitant
Tachycardia Other Serious 35 Female 115 lb 1/21/2010
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/25/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Parkinsonism Other Serious 35 Female 115 lb 2/2/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Hepatitis Hospitalization 60 Female 198 lb 2/4/2010 Other Health Professional Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 60 Female 198 lb 2/16/2010 Physician Belgium
Primary
Concomitant
Parkinsonism Other Serious 35 Female 115 lb 2/22/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 31 Female 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weaning Failure Other Serious 5 Male 4/15/2010
Primary
Secondary
Parotitis Other Serious 60 Female 4/20/2010
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Other Serious 75 Female 4/21/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 4/27/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Post Procedural Haematoma Life Threatening 8/18/2009 63 Male 243 lb 6/15/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2007 68 Male 159 lb 6/17/2010 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 7/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 7/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Jaundice Other Serious 5/13/2010 75 Male 7/30/2010 Physician France
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 59 Female 7/28/2010 Physician New Zealand
Primary
Secondary
Concomitant
Confusional State Other Serious 5/13/2010 75 Male 8/5/2010 Physician Switzerland
Primary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 8/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/1/2007 68 Male 159 lb 11/9/2010 Lawyer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 2/12/2010 33 Female 11/18/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Other Serious 3/11/2010 42 Female 121 lb 11/17/2010 Other Health Professional Japan
Primary
Concomitant
Hyperthermia Death 12/23/2010 2 Male 2/4/2011 Physician France
Primary
Secondary
Respiratory Failure Death 12/23/2010 2 Male 22 lb 2/7/2011 Physician France
Primary
Secondary
Respiratory Failure Death 12/23/2010 2 Male 22 lb 2/9/2011 Other Health Professional France
Primary
Secondary
Splenomegaly Death 12/1/2010 2 Male 22 lb 2/8/2011 Other Health Professional France
Primary
Secondary
Cardiac Failure Death 12/24/2010 2 Male 22 lb 2/10/2011 Other Health Professional France
Primary
Secondary
Pleural Effusion Death 12/23/2010 2 Male 22 lb 2/10/2011 Consumer France
Primary
Secondary
Respiratory Failure Death 12/23/2010 2 Male 22 lb 2/11/2011 Physician France
Primary
Secondary
Pleural Effusion Hospitalization 1 Male 2/7/2011 Pharmacist France
Primary
Concomitant
No Adverse Event Other Serious 2/12/2010 33 Female 3/17/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pain Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Polyuria Other Serious 18 Male 180 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Nephrogenic Diabetes Insipidus Other Serious 18 Male 179 lb 3/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystitis Other Serious 11/14/2008 25 Female 119 lb 4/15/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 10/28/2005 76 Female 49 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 61 Male 177 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 5/19/2005 58 Male 249 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 12/22/2004 73 Female 139 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 4/29/2005 78 Male 210 lb 6/8/2011 Consumer United States
Primary
Concomitant

Drug Data