Morphine combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Other Serious 10/8/2005 74 236 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Spinal Cord Infarction Other Serious 83 Male 1/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Cord Infarction Disability 83 Male 1/19/2006 Other Health Professional Japan
Primary
Concomitant
Somnolence Other Serious 58 Male 1/21/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/19/2005 Male 115 lb 1/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sedation Life Threatening 12/6/2005 44 Female 1/18/2006 Switzerland
Primary
Secondary
Concomitant
Infusion Site Erythema 16 Male 1/30/2006 United States
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Somnolence Other Serious 58 Male 2/21/2006 Physician United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/13/2006 85 Female 93 lb 3/10/2006 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Required Intervention 12/13/2005 57 Male 148 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/7/2006 Spain
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/20/2006 Spain
Primary
Concomitant
Infusion Related Reaction Required Intervention Female 3/23/2006 Turkey
Primary
Concomitant
Infusion Related Reaction Required Intervention Female 3/23/2006 Turkey
Primary
Concomitant
Infusion Related Reaction Required Intervention Female 3/23/2006 Turkey
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Bradycardia Required Intervention Female 3/23/2006 Physician Turkey
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/29/2006 Spain
Primary
Concomitant
Somnolence Other Serious 58 Male 3/6/2006 Physician United States
Primary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/9/2006 18 Female 4/7/2006 Consumer France
Primary
Secondary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 4/10/2006 Pharmacist Canada
Primary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/11/2006 18 Female 4/10/2006
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 176 lb 4/5/2006 Physician Spain
Primary
Concomitant
Hepatitis Fulminant Hospitalization 1/3/2006 28 Female 4/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Unresponsive To Verbal Stimuli Other Serious 69 Female 141 lb 4/6/2006 Physician Hong Kong
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 50 Male 176 lb 4/10/2006 Physician Spain
Primary
Concomitant
Sudden Death Death 3/25/2006 85 Male 163 lb 4/18/2006 Pharmacist Canada
Primary
Concomitant
Ventricular Tachycardia Death 31 Male 165 lb 4/13/2006 Physician Australia
Primary
Concomitant
Platelet Disorder Other Serious 2/6/2006 56 Male 251 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 4/21/2006 Pharmacist Canada
Primary
Concomitant
Haemolysis Other Serious 3/23/2006 50 Male 149 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wrong Drug Administered Other Serious 3/21/2006 35 Male 258 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 5/3/2006 Spain
Primary
Concomitant
Rash Pustular Other Serious 4/26/2006 78 Male 108 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 5/17/2006 Physician Canada
Primary
Concomitant
Wound Haemorrhage Other Serious 35 Female 116 lb 5/23/2006 Physician China
Primary
Secondary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 6/2/2006 Physician Canada
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 3/30/2006 65 Male 6/5/2006 Physician Sweden
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 62 Female 106 lb 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Required Intervention 5/6/2006 54 Male 143 lb 5/31/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 43 Male 216 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Swelling Face Life Threatening 10/3/2004 18 Female 99 lb 5/31/2006 Consumer Australia
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Required Intervention 1/12/2006 67 Female 190 lb 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Other Serious 10/6/2005 46 Female 200 lb 4/7/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 62 Female 106 lb 6/20/2006 Other Health Professional Japan
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 2/25/2006 80 Female 141 lb 6/20/2006 Physician Japan
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 6/30/2006 Physician
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2006 Male 7/12/2006 Other Health Professional Spain
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 44 Male 216 lb 7/14/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 6/19/2006 45 Female 8/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tryptase Increased Other Serious Female 8/9/2006 Physician Ireland
Primary
Concomitant
Rash Pustular Hospitalization 6/19/2006 45 Female 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Required Intervention 6/17/2006 63 Male 8/31/2006 Malaysia
Primary
Concomitant
Wound Secretion Other Serious 35 Female 116 lb 9/1/2006 Other Health Professional China
Primary
Secondary
Concomitant
Pregnancy Other Serious 4/6/2004 39 Female 9/19/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Procedural Complication Other Serious Male 9/29/2006
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 9/29/2006
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Required Intervention 43 Male 10/2/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Tremor Hospitalization 8/31/2006 24 Female 119 lb 10/9/2006 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 1/13/2006 85 Female 93 lb 10/10/2006 Physician United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 174 lb 10/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 11/1/2006 44 Male 11/13/2006 Pharmacist United States
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Vomiting Life Threatening 9/23/2006 Male 240 lb 11/29/2006 Physician Canada
Primary
Concomitant
Metabolic Acidosis Hospitalization 1/1/2006 14 Male 12/6/2006 United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 11/1/2006 51 Female 12/7/2006 Consumer United Kingdom
Primary
Secondary
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 240 lb 12/14/2006 Physician Canada
Primary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/8/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 46 Female 12/21/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 9/2/2006 43 Male 12/14/2006 Other Health Professional Malaysia
Primary
Concomitant
Anaphylactic Reaction Life Threatening 11/1/2006 51 Female 12/13/2006 United Kingdom
Primary
Secondary
Tachypnoea Life Threatening 46 Female 12/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 5 lb 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hypotension Other Serious 9/2/2006 43 Male 12/22/2006 Physician Malaysia
Primary
Concomitant
Tachypnoea Required Intervention 1/1/2006 46 Female 12/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 10/30/2006 46 Female 12/22/2006 United Kingdom
Primary
Secondary
Concomitant
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 240 lb 1/4/2007 Physician Canada
Primary
Concomitant
Tachypnoea Other Serious 46 Female 12/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 4 lb 1/8/2007 France
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/30/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 9/2/2006 43 Male 1/8/2007 Physician Malaysia
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 Female 5 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tachypnoea Other Serious 46 Female 1/15/2007 United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 9/2/2006 43 Male 2/2/2007 Physician Malaysia
Primary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Hypotension Life Threatening 1/24/2007 61 Male 2/13/2007 United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 1/24/2007 61 Male 2/15/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Drowning Death 39 Male 2/12/2007 Japan
Primary
Concomitant
Visual Disturbance Other Serious 49 Female 3/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Neutropenia Hospitalization 1/1/2007 53 Female 3/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Hypertrophy Life Threatening 8/6/2005 48 Male 216 lb 3/14/2007 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Splenomegaly Life Threatening 8/6/2005 48 Male 216 lb 3/26/2007 Physician Switzerland
Primary
Secondary
Concomitant
Tachycardia Other Serious 65 Female 165 lb 4/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 196 lb 4/16/2007 Physician Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/16/2006 43 Male 4/18/2007 Physician France
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 8/9/2005 Female 4/19/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/16/2006 43 Male 4/25/2007 Physician France
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 4/24/2007 Male 173 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Blood Potassium Increased Life Threatening 4/8/2007 51 Male 5/17/2007 United Kingdom
Primary
Concomitant
Blood Potassium Increased Life Threatening 4/8/2007 51 Male 5/16/2007 United Kingdom
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/31/2007 Physician United States
Primary
Secondary
Concomitant
Rales Other Serious 4/29/2007 31 Male 165 lb 6/11/2007 Physician United Kingdom
Primary
Concomitant
Joint Effusion Hospitalization 7/8/2006 72 Male 6/19/2007 Other Health Professional Netherlands
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Wound Infection Bacterial Other Serious 26 Female 7/12/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 65 Male 7/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Circulatory Collapse Life Threatening 40 Female 143 lb 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Lipase Increased Other Serious 8/29/2006 56 Female 7/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 9/26/2006 56 Male 7/30/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Cerebral Haematoma Death 7/18/2007 Male 8/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pupils Unequal Death 7/18/2007 70 Male 8/20/2007 Consumer France
Primary
Secondary
Cerebral Haematoma Death 7/18/2007 Male 8/22/2007 Other Health Professional France
Primary
Secondary
Somnolence Hospitalization 7/18/2007 70 Male 8/15/2007 France
Primary
Secondary
Concomitant
Procedural Pain Other Serious 62 Male 8/23/2007 Belgium
Primary
Secondary
Concomitant
Cerebral Haematoma Death 7/18/2007 Male 8/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 60 Male 119 lb 9/11/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Death 18 Male 9/13/2007 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 2 Female 32 lb 10/11/2007
Primary
Secondary
Concomitant
Thrombosis Other Serious 4/1/2007 Female 121 lb 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 5/14/2007 18 Male 180 lb 10/24/2007 United States
Primary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 11/12/2007 United Kingdom
Primary
Secondary
Concomitant

Drug Data