Mirtazapine combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vertigo 25 Female 1/9/2006 Germany
Primary
Secondary
Drug Dependence Hospitalization 58 Male 1/17/2006 France
Primary
Secondary
Concomitant
Drug Dependence Hospitalization 58 Male 1/20/2006 Physician France
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 57 Male 1/26/2006 Switzerland
Primary
Concomitant
Nutritional Condition Abnormal Hospitalization 58 Male 2/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 2/5/2006 22 Male 2/17/2006 Consumer United Kingdom
Primary
Concomitant
Rash Erythematous 2/3/2005 58 Female 2/17/2006 Canada
Primary
Concomitant
Wheezing 1/12/2005 20 Female 2/17/2006 Canada
Primary
Concomitant
Tremor Hospitalization 1/31/2006 73 Female 3/20/2006 Switzerland
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/18/2006 45 Female 4/6/2006 Pharmacist Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/28/2002 43 Male 4/7/2006 Physician Australia
Primary
Secondary
Concomitant
Restless Legs Syndrome Hospitalization 59 Female 4/6/2006 Switzerland
Primary
Secondary
Sperm Count Decreased Disability 31 Male 4/13/2006 Other Health Professional Australia
Primary
Secondary
Torsade De Pointes Life Threatening 10/1/2004 40 Male 4/21/2006 France
Primary
Secondary
Pancytopenia Hospitalization 1/18/2006 45 Male 4/20/2006 Australia
Primary
Secondary
Concomitant
Restless Legs Syndrome Hospitalization 59 Female 4/26/2006 Switzerland
Primary
Secondary
Scoliosis Hospitalization 59 Female 4/26/2006 Switzerland
Primary
Secondary
Cardiac Disorder Death 1/1/2006 90 Female 5/22/2006 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/1/2005 Male 6/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Dissection Death 1/1/2006 90 Female 6/21/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/23/2005 44 Male 4/25/2006 United States
Primary
Concomitant
Nausea Hospitalization 3/9/2006 79 Female 7/28/2006 Australia
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/14/2006 89 Unknown 8/4/2006 United Kingdom
Primary
Concomitant
Status Epilepticus Other Serious 2/5/2006 22 Male 8/31/2006 Consumer United Kingdom
Primary
Concomitant
Somnolence Other Serious 7/2/2006 89 9/7/2006 Denmark
Primary
Concomitant
Granulocytopenia Death 1/1/2006 56 Male 9/18/2006 United States
Primary
Concomitant
Vomiting Other Serious Female 10/13/2006 Consumer Ireland
Primary
Secondary
Drug Interaction Female 10/19/2006 Australia
Primary
Secondary
Overdose Death 9/26/2006 52 Male 190 lb 10/23/2006 United States
Primary
Concomitant
Neutropenia Hospitalization 8/31/2006 44 Female 11/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 9/28/2006 43 Male 205 lb 12/6/2006 Other Health Professional France
Primary
Concomitant
Vomiting Life Threatening Female 12/28/2006 Consumer Ireland
Primary
Secondary
Vomiting Life Threatening Female 1/4/2007 Consumer Ireland
Primary
Secondary
Cytolytic Hepatitis Hospitalization 11/23/2005 30 Female 1/18/2007 France
Primary
Secondary
Concomitant
Tardive Dyskinesia Disability 8/1/2006 58 Male 6/22/2007 United Kingdom
Primary
Concomitant
Tongue Paralysis Disability 8/1/2006 58 Male 6/29/2007 United Kingdom
Primary
Concomitant
Tremor Other Serious 67 Female 7/24/2007
Primary
Secondary
Syncope Hospitalization 6/29/2007 43 Male 8/28/2007 France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 11/19/2007 47 Female 12/4/2007 Physician Germany
Primary
Secondary
Somnolence Other Serious 22 Female 1/10/2008 France
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 8/1/2003 Female 1/16/2008 Physician Australia
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 8/1/2003 Female 1/16/2008 Physician Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 8/1/2003 19 Female 1/30/2008 Physician Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 2/27/2008 Physician Germany
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/23/2008 United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/23/2008 United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization 11/16/2007 Female 126 lb 10/2/2008 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 7/2/2006 89 10/22/2008 Denmark
Primary
Concomitant
Tremor Female 113 lb 12/12/2008 United States
Primary
Concomitant
Paranoia Other Serious 1/1/2007 2/11/2009 Other Health Professional Slovenia
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/17/2008 74 Female 2/25/2009 Physician Italy
Primary
Secondary
Concomitant
Angioedema Hospitalization 12/1/2008 39 Female 2/27/2009 France
Primary
Concomitant
Hypersexuality Other Serious 7/1/2008 67 Male 132 lb 3/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypersexuality 7/1/2008 67 Male 3/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Insomnia Other Serious 7/1/2008 67 Male 132 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/17/2008 74 Female 3/11/2009 Italy
Primary
Secondary
Concomitant
Hypersexuality 7/1/2008 67 Male 3/16/2009 United Kingdom
Primary
Concomitant
Psychotic Disorder Hospitalization 2/5/2009 65 Female 3/19/2009 Physician Czech Republic
Primary
Secondary
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 4/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Adrenocortical Insufficiency Acute Hospitalization 2/25/2008 76 Male 4/23/2009 Spain
Primary
Secondary
Concomitant
Speech Disorder Other Serious 37 Male 4/29/2009 Physician Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/5/2007 Female 6/5/2009 Physician Australia
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 8/18/2009 Consumer Germany
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/9/2009 Physician France
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2008 40 Male 9/3/2009
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2008 40 Male 9/9/2009 United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 9/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 10/12/2009 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 10/14/2009 United Kingdom
Primary
Concomitant
Hypoaesthesia Other Serious 10/17/2009 33 Male 11/3/2009 Physician Japan
Primary
Concomitant
Encephalopathy Hospitalization 5/6/2009 57 Female 11/17/2009 Consumer Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2009 Male 11/17/2009 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 11/24/2009 Pharmacist United Kingdom
Primary
Concomitant
Somnolence 10/17/2009 33 Male 11/19/2009 Physician Japan
Primary
Concomitant
Parkinsonism Other Serious 78 Male 12/16/2009 Physician United States
Primary
Concomitant
Feeling Jittery Other Serious 12/4/2009 51 Female 12/22/2009 Physician Japan
Primary
Concomitant
Encephalopathy Hospitalization 5/6/2009 57 Female 1/4/2010 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2009 Male 3/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2009 Male 3/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 71 Female 3/12/2010 Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/5/2010 42 Female 3/22/2010 Physician Japan
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 1/24/2010 77 Female 4/2/2010 France
Primary
Secondary
Concomitant
Urinary Retention Other Serious 71 Female 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Life Threatening 12/19/2009 44 Female 5/13/2010 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 5/24/2010 France
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 5/20/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 231 lb 5/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Underdose Other Serious 12/4/2009 51 Female 5/27/2010 Japan
Primary
Concomitant
Weight Increased Other Serious 10/1/2008 40 Male 5/27/2010 United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 6/10/2010 United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 1/29/2010 42 Female 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Suspiciousness Other Serious 12/8/2009 45 Female 7/12/2010 Physician Japan
Primary
Concomitant
Suicide Attempt Life Threatening 28 Female 176 lb 7/19/2010 Pharmacist Germany
Primary
Concomitant
Bipolar Disorder Other Serious Male 8/2/2010 Physician United Kingdom
Primary
Concomitant
Depression Suicidal Other Serious 42 Female 8/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Depression Suicidal Other Serious 42 Female 8/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization 4/16/2010 35 Male 8/24/2010 Other Health Professional Ireland
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2007 65 Female 117 lb 8/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 6/7/2010 33 Male 8/30/2010 Physician Japan
Primary
Concomitant
Thymol Turbidity Test Increased Other Serious 6/7/2010 33 Male 9/29/2010 Physician Japan
Primary
Concomitant
Thymol Turbidity Test Increased Other Serious 6/7/2010 33 Male 11/10/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2007 65 Female 117 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Psychomotor Hyperactivity Death 2/18/2010 75 Female 12/31/2010 Other Health Professional Italy
Primary
Concomitant
Haemoglobin Decreased Other Serious 12/23/2010 69 Female 151 lb 2/28/2011 Physician Germany
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 12/23/2010 69 Female 151 lb 3/23/2011 Physician Germany
Primary
Concomitant
Interacting
Lower Respiratory Tract Infection Hospitalization Male 5/3/2011 Pharmacist Ireland
Primary
Concomitant
Memory Impairment Hospitalization 1/1/2010 46 Male 5/25/2011 Physician Germany
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 1/1/2010 46 Male 5/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 4/27/2011 Male 4 lb 6/6/2011 Physician Japan
Primary
Secondary
Bipolar Ii Disorder Hospitalization 63 Female 6/16/2011 Other Health Professional Japan
Primary
Concomitant
Hemiparesis Disability 2/1/2007 47 Male 6/16/2011 Consumer United Kingdom
Primary
Concomitant
Kidney Infection Hospitalization Male 6/9/2011 Pharmacist Ireland
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2011 Male 6/28/2011 Consumer Portugal
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/15/2011 28 Male 6/23/2011 Other Health Professional
Primary
Concomitant
Frontotemporal Dementia Hospitalization 43 Male 7/6/2011 Physician Poland
Primary
Secondary
Concomitant
Schizophrenia Life Threatening 6/6/2011 23 Male 170 lb 7/12/2011 Physician Australia
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/15/2011 28 Male 7/5/2011 Pharmacist
Primary
Concomitant
Developmental Delay Congenital Anomaly 11/1/2010 Male 9 lb 7/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 43 Male 7/18/2011 Physician Poland
Primary
Secondary
Concomitant
Frontotemporal Dementia Hospitalization 43 Male 7/13/2011 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/15/2011 28 Male 7/22/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Convulsion Death Male 177 lb 7/29/2011 Physician Australia
Primary
Concomitant
Multiple Sclerosis Other Serious 6/1/2011 37 Male 9/13/2011 Consumer South Africa
Primary
Concomitant
Lung Disorder Hospitalization 42 Male 9/14/2011 Consumer Australia
Primary
Concomitant
Arthralgia Other Serious 6/1/2011 37 Male 9/30/2011 Consumer South Africa
Primary
Concomitant
Chest Discomfort Hospitalization 42 Male 9/29/2011 Consumer Australia
Primary
Concomitant
Drug Ineffective Hospitalization 43 Male 10/11/2011 Physician
Primary
Secondary
Concomitant
Gait Disturbance Disability 8/1/2011 38 Female 10/18/2011 Other Health Professional Germany
Primary
Concomitant
Toxicity To Various Agents Death 45 Female 10/21/2011 Other Health Professional Portugal
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/15/2011 28 Male 10/24/2011 Pharmacist
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/1/2011 58 Female 10/31/2011 Other Health Professional Ireland
Primary
Concomitant
Hypotonia Congenital Anomaly 11/1/2010 Male 9 lb 11/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/1/2011 58 Female 11/3/2011 Physician Ireland
Primary
Concomitant
Parkinsonism Other Serious 67 Female 11/3/2011 Other Health Professional United States
Primary
Secondary
Lung Disorder Hospitalization 42 Male 11/3/2011 Consumer Australia
Primary
Concomitant
Multiple Sclerosis Other Serious 6/1/2011 37 Male 1/24/2012 Consumer South Africa
Primary
Concomitant
Toxicity To Various Agents Death 64 Female 187 lb 2/1/2012 Other Health Professional Italy
Primary
Secondary
Microangiopathy Hospitalization 1/10/2012 Female 176 lb 2/23/2012 Physician France
Primary
Concomitant
Arrhythmia Other Serious 2/14/2012 75 Female 3/7/2012 Other Health Professional Italy
Primary
Secondary
Concomitant

Drug Data