Mirtazapine combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Serotonin Syndrome Hospitalization 10/5/2005 29 Male 197 lb 10/30/2005 Pharmacist United States
Primary
Secondary
Paraesthesia Hospitalization 35 Male 9/11/2006 United States
Primary
Secondary
Gun Shot Wound Death 49 Female 10/6/2006 United States
Primary
Secondary
Concomitant
Mouth Injury Death 49 Female 12/14/2006 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 9/1/2006 Male 243 lb 11/9/2006 Pharmacist United States
Primary
Concomitant
Gun Shot Wound Death 6/4/2004 Female 3/27/2007 Lawyer United States
Primary
Secondary
Concomitant
Somnambulism 35 Female 9/20/2007 Other Health Professional Canada
Primary
Concomitant
Pancreatitis Chronic Other Serious 3/1/2006 33 Female 121 lb 12/10/2007 Physician United States
Primary
Concomitant
Somnambulism 12/29/2006 35 Female 12/12/2007 Other Health Professional Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 10/1/2007 46 Male 1/10/2008 Physician Canada
Primary
Concomitant
Vision Blurred Other Serious 6/1/2008 Male 230 lb 6/30/2008 Physician United States
Primary
Concomitant
Interacting
Vision Blurred Other Serious 6/1/2008 Male 230 lb 7/2/2008 Physician United States
Primary
Concomitant
Interacting
Epistaxis 9/9/2008 38 Male 210 lb 9/9/2008 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 47 Female 12/19/2008 Physician United States
Primary
Secondary
Overdose Death 47 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 47 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 1/1/2007 47 Female 12/29/2008 Physician United States
Primary
Secondary
Completed Suicide Death 47 Female 1/16/2009 United States
Primary
Secondary
Overdose Death 47 Female 1/16/2009 Physician United States
Primary
Secondary
Completed Suicide Death 47 Female 1/20/2009 Other Health Professional United States
Primary
Secondary
Intentional Drug Misuse Death 47 Female 1/15/2009 Physician United States
Primary
Secondary
Completed Suicide Death 1/30/2009 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2007 47 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Completed Suicide Death 47 Female 2/2/2009 Physician United States
Primary
Secondary
Multiple Drug Overdose Death 47 Female 2/27/2009 Physician United States
Primary
Secondary
Nephropathy Toxic Other Serious 1/15/2009 76 Female 110 lb 3/31/2009 Pharmacist United States
Primary
Concomitant
Overdose Death 47 Female 6/23/2009 Physician United States
Primary
Secondary
Overdose Death 47 Female 7/13/2009 Physician United States
Primary
Secondary
Diabetic Neuropathy Other Serious 2/28/2006 45 Male 228 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Myoclonus Other Serious Female 8/4/2009 Physician United States
Primary
Secondary
Tremor Other Serious Female 8/11/2009 United States
Primary
Secondary
Overdose Death 1/1/2007 47 Female 8/24/2009 Physician United States
Primary
Secondary
Pancreatitis Chronic Other Serious 10/10/2005 32 Female 134 lb 9/11/2009 United States
Primary
Concomitant
Myoclonus Other Serious Female 9/15/2009 Physician United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/22/2008 57 Male 10/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 38 Male 11/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Death 5/12/2009 28 Female 12/18/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Death 5/12/2009 28 Female 12/18/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 49 Male 1/11/2010 Other Health Professional United States
Primary
Secondary
Status Epilepticus Hospitalization Male 172 lb 12/30/2009 Other Health Professional Germany
Primary
Concomitant
Respiratory Arrest Death 49 Male 1/15/2010
Primary
Secondary
Drug Toxicity Other Serious 49 Male 1/25/2010 Physician United States
Primary
Secondary
Poisoning Life Threatening 1/1/2008 49 Male 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 49 Male 2/2/2010 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 49 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 49 Male 2/1/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 49 Male 2/19/2010
Primary
Secondary
Completed Suicide Death 49 Male 2/26/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 49 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 49 Male 3/25/2010 Other Health Professional United States
Primary
Secondary
Leukocytosis Hospitalization 62 Female 226 lb Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 72 Male 8/4/2010 Chile
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 72 Male 8/16/2010 Chile
Primary
Secondary
Concomitant
Overdose Other Serious 8/20/2009 Female 1/26/2011 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 39 Male 6/2/2011 Physician Spain
Primary
Secondary
Concomitant
Drug Ineffective For Unapproved Indication 6/21/2011 Physician Spain
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 47 Female 7/11/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2007 47 Female 7/14/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2007 47 Female 7/14/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2008 49 Male 7/22/2011 Physician United States
Primary
Secondary
Asthenia Hospitalization 5/1/2011 32 Male 130 lb 7/18/2011 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious Female 205 lb 8/8/2011 Lawyer United States
Primary
Concomitant
Intervertebral Disc Displacement Hospitalization 1/1/2010 56 Female 8/18/2011 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/20/2011 26 Male 260 lb 8/22/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 1/1/2007 47 Female 8/4/2011 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 36 10/20/2011 Other Health Professional United States
Primary
Secondary
Medication Error Other Serious 9/14/2011 49 Female 11/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Head Injury Other Serious 1/1/2011 49 Female 154 lb 11/22/2011 Physician Turkey
Primary
Concomitant
Chest Discomfort Hospitalization 10/31/2011 64 Male 285 lb 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 10/31/2011 64 Male 285 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/31/2011 64 Male 285 lb 12/19/2011 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Death 6/4/2004 49 Female 12/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Impulsive Behaviour Other Serious 12/5/2011 41 Female 12/22/2011 Pharmacist Japan
Primary
Concomitant
Compulsive Shopping Other Serious 41 Female 12/16/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2010 49 Female 12/26/2011 Physician United States
Primary
Secondary
Pruritus Hospitalization 10/21/2011 63 Female 1/5/2012 Consumer France
Primary
Concomitant
Pain Other Serious 5/1/2011 32 Male 130 lb 1/10/2012 Consumer United States
Primary
Concomitant
Dysarthria Hospitalization 10/1/2003 55 Male 185 lb 1/30/2012 Lawyer United States
Primary
Concomitant
Therapeutic Product Ineffective Required Intervention 8/30/2010 80 Male 260 lb 2/9/2012 Other Health Professional United States
Primary
Concomitant
Aphasia Other Serious 2/20/2012 74 Female 165 lb 3/15/2012 Physician Germany
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 49 Female 4/13/2012 Physician United States
Primary
Secondary
Fall Disability 1/1/2011 75 Female 5/8/2012 Consumer Canada
Primary
Concomitant
Hepatitis Fulminant Life Threatening 3/28/2012 30 Male 5/16/2012 Other Health Professional France
Primary
Secondary
Concomitant
Fatigue Death 5/2/2012 50 Male 5/18/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 5/2/2012 50 Male 5/21/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 5/2/2012 50 Male 5/23/2012 Other Health Professional Germany
Primary
Secondary
Hallucination 56 Male 194 lb 5/23/2012 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 3/28/2012 30 Male 5/23/2012 Other Health Professional France
Primary
Secondary
Concomitant
Application Site Erythema 1/1/2011 5/30/2012 Consumer United States
Primary
Concomitant
Fatigue Death 5/2/2012 50 Male 6/1/2012 Other Health Professional Germany
Primary
Secondary
Suicide Attempt Hospitalization 5/2/2012 50 Male 6/1/2012 Other Health Professional Germany
Primary
Secondary
Fatigue Hospitalization 5/2/2012 50 Male 6/5/2012 Other Health Professional Germany
Primary
Secondary
Suicide Attempt Hospitalization 5/2/2012 50 6/4/2012 Other Health Professional Germany
Primary
Secondary
Application Site Erosion 1/1/2011 6/11/2012 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 12/5/2011 49 Female 6/29/2012 Other Health Professional United Kingdom
Primary
Secondary
Eosinophil Count Decreased Other Serious 12/5/2011 49 Female 6/29/2012 Physician United Kingdom
Primary
Secondary
Scratch Other Serious 12/5/2011 49 Female 7/5/2012 Physician United Kingdom
Primary
Secondary
Injury Other Serious 12/5/2011 49 Female 7/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Neutrophil Count Decreased Other Serious 12/5/2011 49 Female 7/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Off Label Use Life Threatening 1/1/2007 49 Female 7/10/2012 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/5/2011 49 Female 7/10/2012 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 12/5/2011 49 Female 7/12/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Other Serious 12/5/2011 50 Female 7/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Life Threatening 1/9/2012 49 Female 7/13/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2007 49 Female 7/16/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Scratch Other Serious 12/5/2011 49 Female 7/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scratch Other Serious 12/5/2011 49 Female 7/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/5/2011 49 Female 7/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Platelet Count Decreased Other Serious 1/1/2007 49 Female 7/20/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Other Serious 12/5/2011 50 Female 7/23/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injury Life Threatening 12/5/2011 49 Female 7/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/5/2011 49 Female 7/23/2012 Physician United Kingdom
Primary
Secondary
Toothache Other Serious 12/5/2011 49 Female 7/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Road Traffic Accident Other Serious 12/5/2011 49 Female 7/11/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/9/2012 49 Female 7/26/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/5/2011 50 Female 7/13/2012 Physician United Kingdom
Primary
Secondary
Toothache Other Serious 12/5/2011 7/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Injury Other Serious 12/5/2011 49 Female 8/1/2012 Physician United Kingdom
Primary
Secondary
Scratch Other Serious 12/5/2011 49 Female 8/1/2012 Other Health Professional United Kingdom
Primary
Secondary
Injury Other Serious 12/5/2011 49 Female 8/1/2012 Other Health Professional United Kingdom
Primary
Secondary
Injury Other Serious 1/9/2012 49 Female 7/20/2012 Physician Denmark
Primary
Secondary
Tooth Infection Other Serious 12/5/2011 49 Female 8/2/2012 Physician United Kingdom
Primary
Secondary
Wound Other Serious 12/5/2011 50 Female 7/20/2012 Physician
Primary
Secondary
Eosinophil Count Decreased Other Serious 12/5/2011 49 Female 8/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Life Threatening 1/1/2007 49 Female 8/3/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Toothache Life Threatening 12/5/2011 49 Female 8/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Road Traffic Accident Hospitalization 12/5/2011 50 Female 8/4/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/9/2012 49 Female 8/4/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 12/5/2011 49 Female 8/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Tooth Infection Other Serious 12/5/2011 49 Female 8/7/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 12/5/2011 49 Female 8/8/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 12/5/2011 49 Female 7/25/2012
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 12/5/2011 8/8/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/5/2011 49 Female 8/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 7/19/2010 32 Female 8/13/2012 Consumer United States
Primary
Concomitant
Scratch Other Serious 1/9/2012 49 Female 8/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 1/9/2012 49 Female 8/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Life Threatening 12/5/2011 50 Female 7/30/2012 Physician
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 12/5/2011 49 Female 8/13/2012 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 12/5/2011 49 Female 8/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/9/2012 49 Female 8/3/2012 Physician Denmark
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 12/5/2011 49 Female 8/20/2012 Physician United Kingdom
Primary
Secondary
Scratch Other Serious 12/5/2011 49 Female 8/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Tooth Infection Other Serious 12/5/2011 49 Female 8/22/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Eosinophil Count Decreased Other Serious 1/1/2007 49 Female 8/23/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2007 49 Female 9/28/2012 Physician Gb
Primary
Secondary
Concomitant
Toothache Other Serious 12/5/2011 49 Female 9/21/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/9/2012 49 Female 11/14/2012 Physician Dk
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 152 lb 3/7/2013 Physician Ca
Primary
Concomitant

Drug Data