Mirtazapine combined with Morphine

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Drug Dependence Hospitalization 58 Male 1/17/2006 France
Primary
Secondary
Concomitant
Sedation Life Threatening 12/6/2005 44 Female 1/18/2006 Switzerland
Primary
Secondary
Concomitant
Drug Dependence Hospitalization 58 Male 1/20/2006 Physician France
Primary
Secondary
Concomitant
Nutritional Condition Abnormal Hospitalization 58 Male 2/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Drug Toxicity Death 36 Female 163 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization Male 2/17/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Toxicity Death 36 Female 163 lb 2/28/2006 United States
Primary
Secondary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 4/19/2006 Switzerland
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 5/12/2006 United States
Primary
Concomitant
Skin Laceration Other Serious 3/6/2006 Male 6/2/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 6/14/2006 United States
Primary
Concomitant
Scoliosis Death 12/16/2004 61 Female 119 lb 8/1/2006 United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 3/6/2006 Male 8/10/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 5/1/2006 Female 8/14/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 9/6/2006 United States
Primary
Concomitant
Drug Toxicity Other Serious 36 Female 163 lb 9/27/2006 United States
Primary
Secondary
Concomitant
Pain Required Intervention 1/1/2004 Female 10/19/2006 Lawyer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2005 66 Female 10/23/2006 Switzerland
Primary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 42 Female 159 lb 11/16/2006
Primary
Secondary
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2004 Female 1/22/2007 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 10/2/2006 61 Female 2/9/2007 Physician Germany
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 11/6/2006 55 Male 164 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/16/2004 Female 119 lb 3/2/2007 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/18/2002 Female 3/8/2007 Consumer United States
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/2/2006 61 Female 3/7/2007 Physician Germany
Primary
Concomitant
Syncope Other Serious 12/18/2002 Female 3/20/2007 Lawyer United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2003 Male 3/23/2007 Lawyer United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2007 56 Female 3/29/2007 Consumer Germany
Primary
Concomitant
Somnolence Hospitalization 1/1/2007 56 Female 4/27/2007 Consumer Germany
Primary
Concomitant
Tendonitis Other Serious 10/1/2005 62 Male 5/18/2007 Physician
Primary
Secondary
Concomitant
Tendonitis Hospitalization 10/1/2005 62 Male 5/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tendonitis Hospitalization 10/1/2005 62 Male 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 6/3/2007 Female 114 lb 6/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/3/2007 59 Female 115 lb 6/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tendonitis Hospitalization 10/1/2005 62 Male 6/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2007 56 Female 6/29/2007 Consumer Germany
Primary
Concomitant
Ulcer Hospitalization 10/1/2005 62 Male 157 lb 7/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/5/2007 74 Male 106 lb 8/17/2007 Physician United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Angioedema 10/15/2007 54 Male 228 lb 11/16/2007 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2003 Male 12/20/2007 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/14/2008 Female 357 lb 3/6/2008 Pharmacist United Kingdom
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 4/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 38 Male 4/16/2008 Sweden
Primary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 5/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 6/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Trigeminal Neuralgia Other Serious 12/29/2001 58 Female 6/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ischaemia Death 8/11/2008 84 Male 9/4/2008 Consumer Italy
Primary
Concomitant
Metrorrhagia 4/11/2008 Female 198 lb 9/12/2008 United States
Primary
Concomitant
Urinary Hesitation 1/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Syncope Other Serious 6/13/2008 50 Female 146 lb 9/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Other Serious 11/24/2007 58 Male 3/21/2008 Physician United States
Primary
Concomitant
Ischaemia Death 8/11/2008 84 Male 11/10/2008 Consumer Italy
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/28/2008 59 Male 141 lb 11/19/2008 Consumer United States
Primary
Concomitant
Peroneal Nerve Palsy Disability 9/1/2008 55 Female 11/17/2008 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/6/2008 Male 159 lb 11/26/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 6/1/2008 Female 126 lb 12/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting 3/1/2008 Female 12/9/2008 Consumer United States
Primary
Concomitant
Death Death 1/29/2009 Female 145 lb 2/4/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Death Female 145 lb 2/19/2009 Other Health Professional United States
Primary
Concomitant
Streptococcal Sepsis Other Serious 6/1/2008 Female 126 lb 3/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/6/2008 Male 159 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 1/1/2007 35 Male 3/5/2009 Consumer United States
Primary
Concomitant
Systemic Candida Other Serious 11/27/2008 55 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 41 Male 4/2/2009
Primary
Secondary
Concomitant
Somnolence Other Serious 4/20/2004 77 Male 190 lb 4/3/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 8/12/2003 60 Male 216 lb 4/3/2009 United States
Primary
Concomitant
Radiation Injury Disability 9/1/2008 55 Female 4/1/2009 Physician United States
Primary
Concomitant
Death Death Male 4/21/2009
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 6/1/2008 Female 126 lb 5/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 5/3/2009 19 Male 143 lb 8/21/2009 Physician Austria
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/1/2005 58 Male 150 lb 9/23/2009 United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 6/10/2009 74 Female 131 lb 6/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/1/2009 76 Female 11/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Impairment Other Serious 9/1/2009 76 Female 11/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2008 39 Female 11/26/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 1/1/2007 35 Male 12/1/2009 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 10/22/2009 65 Male 116 lb 11/17/2009 Pharmacist United States
Primary
Concomitant
Hypersensitivity 11/1/2007 51 Female 82 lb 1/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 1/1/2007 51 Female 82 lb 2/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Narcotic Intoxication Death Male 254 lb 2/26/2010 Physician United States
Primary
Concomitant
Drug Toxicity Death 47 Female 163 lb 2/28/2010 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death Female 200 lb 3/1/2010 Physician United States
Primary
Secondary
Acute Hepatic Failure Other Serious 1/17/2010 57 Male 195 lb 3/25/2010 Pharmacist Canada
Primary
Concomitant
Hypersensitivity Other Serious 1/1/2007 51 Female 82 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease 57 Male 99 lb 4/21/2010 Consumer United States
Primary
Concomitant
Obesity Death 42 Female 5/10/2010 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2002 43 Male 6/1/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/5/2010 43 Male 6/17/2010 United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Death 42 Female 6/14/2010 Australia
Primary
Secondary
Concomitant
Spinal Deformity Other Serious 5/1/2005 34 Male 143 lb 7/2/2010 United States
Primary
Concomitant
Neuroendocrine Tumour Death 6/22/2010 51 Female 7/19/2010 Physician United Kingdom
Primary
Concomitant
Respiratory Arrest Life Threatening 7/11/2010 72 Female 7/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 7/11/2010 72 Female 7/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Death 42 Female 8/4/2010 Other Health Professional Australia
Primary
Secondary
Serotonin Syndrome Death 42 Female 8/4/2010 Other Health Professional Australia
Primary
Secondary
Serotonin Syndrome Death 42 Female 8/4/2010 Other Health Professional Australia
Primary
Secondary
Serotonin Syndrome Death 42 Female 8/5/2010 Other Health Professional Australia
Primary
Secondary
Syncope Other Serious 12/18/2002 65 Female 8/6/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Life Threatening 7/11/2010 72 Female 8/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Serotonin Syndrome Other Serious 42 Female 8/12/2010 Australia
Primary
Secondary
Sepsis Other Serious 1/1/2008 42 Female 9/2/2010 Lawyer United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Overdose Death 33 Male 9/22/2010 Other Health Professional Sweden
Primary
Secondary
Overdose Death 33 Male 9/22/2010 Other Health Professional Sweden
Primary
Secondary
Overdose Death 33 Male 9/22/2010 Other Health Professional Sweden
Primary
Secondary
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 4/17/2008 71 Male 9/30/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/11/2010 72 Female 10/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Increased Life Threatening 7/11/2010 72 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/11/2010 72 Female 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 10/16/2010 50 Male 141 lb 10/25/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/11/2010 72 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 7/11/2010 72 Female 11/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 21 Female 11/16/2010
Primary
Secondary
Sepsis Other Serious 4/17/2008 71 Male 12/6/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 12/24/2010 United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 11/2/2009 68 Male 12/30/2010 Pharmacist United States
Primary
Concomitant
Cardiac Disorder Other Serious 4/17/2008 71 Male 139 lb 1/20/2011 Other Health Professional United States
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 5/7/2005 58 Male 174 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Death 2/17/2011 62 Female 170 lb 3/2/2011 Pharmacist United Kingdom
Primary
Concomitant
Chills Death 1/21/2011 62 Female 110 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abnormal Dreams Other Serious 2/17/2011 56 Male 3/15/2011 Consumer Canada
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 2/17/2011 62 Female 170 lb 3/18/2011 Pharmacist United Kingdom
Primary
Concomitant
Papilloma Viral Infection Other Serious 11/19/2009 57 Male 141 lb 3/23/2011 Physician United States
Primary
Concomitant
Circulatory Collapse Hospitalization 1/21/2011 62 Female 110 lb 3/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Catheter Site Phlebitis Hospitalization 2/8/2011 74 Male 3/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Herpes Simplex Serology Positive Other Serious 5/7/2005 58 Male 174 lb 4/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Injury Other Serious 59 Female 3/29/2011 Consumer United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 2/8/2011 74 Male 4/11/2011 Physician France
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 2/17/2011 62 Female 170 lb 4/15/2011 Pharmacist United Kingdom
Primary
Concomitant
Myocardial Infarction Death 2/17/2011 62 Female 170 lb 4/18/2011 Pharmacist United Kingdom
Primary
Concomitant
Toxicity To Various Agents Death 42 Female 5/9/2011 Other Health Professional Australia
Primary
Secondary
Interacting
Catheter Site Phlebitis Hospitalization 2/8/2011 74 Male 5/12/2011 Other Health Professional France
Primary
Secondary
Concomitant
Visceral Arterial Ischaemia Death 5/8/2011 45 Female 150 lb 5/27/2011 Physician United States
Primary
Concomitant