Midazolam combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nausea Hospitalization 38 Male 220 lb 3/16/2006 Other Health Professional United States
Primary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 4/17/2006 Other Health Professional Japan
Primary
Concomitant
Proteinuria Other Serious 5/30/2006 Male 6/28/2006 Other Health Professional Japan
Primary
Secondary
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/3/2006 Female 11/30/2006 Other Health Professional Japan
Primary
Concomitant
Hypoxia Life Threatening 6/3/2006 Male 11/30/2006 Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 15 Female 44 lb 10/18/2007 Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Death 53 Female 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 7/30/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Required Intervention 49 Female 9/22/2008 Canada
Primary
Secondary
Concomitant
Stillbirth Other Serious 20 Female 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 60 Male 12/23/2008 Japan
Primary
Concomitant
Resuscitation Hospitalization 2 Female 12/22/2008 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 60 Female 11/12/2009 Other Health Professional France
Primary
Concomitant
Hypertensive Crisis Life Threatening 87 Female 2/25/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 67 Female 99 lb 3/2/2010 Other Health Professional Japan
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 3/21/2007 Female 9 lb 6/17/2010 Physician United States
Primary
Secondary
Ventricular Tachycardia Other Serious 10/1/2007 68 Male 159 lb 6/17/2010 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 7/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Electromechanical Dissociation Other Serious 21 Male 126 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Wound Dehiscence Other Serious 10/1/2007 68 Male 159 lb 11/9/2010 Lawyer United States
Primary
Concomitant
Pulse Absent Other Serious 21 Male 126 lb 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 31 Male 11/19/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 5/27/2010 74 Male 163 lb 11/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 49 Female 11/29/2010 Other Health Professional Austria
Primary
Concomitant
Interacting
Cardiac Arrest Life Threatening 5/27/2010 74 Male 163 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Convulsion Other Serious 45 Female 134 lb 12/20/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Shock Life Threatening 11/25/2010 64 Female 12/21/2010 Physician France
Primary
Secondary
Concomitant
Apnoea Other Serious 2/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Apnoea Other Serious 2/14/2011 Physician Italy
Primary
Secondary
Concomitant
Blindness Unilateral Other Serious 73 Male 2/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fear Other Serious 11/1/2006 70 Male 160 lb 3/17/2011 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 11/1/2006 70 Male 160 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Body Temperature Increased Other Serious 2 Male 22 lb 3/18/2011 Physician Japan
Primary
Concomitant
Pain Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 58 Female 3/21/2011 Other Health Professional New Zealand
Primary
Concomitant
Cardiac Arrest Hospitalization 2 Female 23 lb 4/25/2011 Canada
Primary
Secondary
Concomitant
Dyspnoea Other Serious 6/22/2009 22 Female 77 lb 4/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 5/13/2005 62 Male 245 lb 4/26/2011 Lawyer United States
Primary
Concomitant
Nervousness Disability 57 Female 170 lb 5/2/2011 Lawyer United States
Primary
Concomitant
Body Temperature Decreased Other Serious 2 Male 22 lb 5/3/2011 Physician Japan
Primary
Concomitant
Injury Death 4/30/2004 0 Female 30 lb 6/6/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 10/2/2004 64 Female 125 lb 6/8/2011 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 1 Male 13 lb 11/14/2011 Other Health Professional India
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 1 Male 13 lb 11/9/2011 Physician India
Primary
Concomitant
Rhabdomyolysis Other Serious 9/14/2011 26 Male 139 lb 12/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nodal Arrhythmia Other Serious 3 Male 1/20/2012 Physician United States
Primary
Concomitant
Dilatation Ventricular Hospitalization 40 Male 1/23/2012 United States
Primary
Secondary
Fat Embolism Other Serious 76 Male 209 lb 2/7/2012 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Other Serious 76 Male 209 lb 2/3/2012 Other Health Professional United States
Primary
Concomitant
Depressed Level Of Consciousness Life Threatening 46 Female 154 lb 2/14/2012 Physician Greece
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 46 Female 154 lb 2/22/2012 Other Health Professional Greece
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 46 Female 154 lb 2/22/2012 Other Health Professional Greece
Primary
Secondary
Concomitant
Mydriasis Other Serious 46 Female 154 lb 2/21/2012 Other Health Professional Greece
Primary
Concomitant
Interacting
Anticholinergic Syndrome Other Serious 49 Female 154 lb 2/22/2012 Other Health Professional Greece
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 28 Female 3/8/2012 Physician France
Primary
Secondary
Concomitant
Hypotension Life Threatening 4/21/2011 62 Male 134 lb 3/8/2012 Physician Japan
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious 25 Female 115 lb 3/15/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 4/21/2011 62 Male 134 lb 3/16/2012 Physician Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 4/21/2011 62 Male 134 lb 3/19/2012 Physician Japan
Primary
Secondary
Concomitant
Apnoea Other Serious 46 Female 154 lb 3/26/2012 Physician Greece
Primary
Secondary
Concomitant
Interacting
Hypertension Other Serious 3/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 3/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Embolism Hospitalization 76 Male 209 lb 3/28/2012 Other Health Professional United States
Primary
Concomitant
Pain Life Threatening 46 Female 154 lb 3/30/2012 Other Health Professional Greece
Primary
Secondary
Concomitant
Interacting
Drug Interaction Other Serious 46 Female 154 lb 3/30/2012 Physician Greece
Primary
Secondary
Concomitant
Interacting
Cough Other Serious 1/26/2012 55 Female 3/29/2012 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2012 38 Male 3/29/2012 Physician United Kingdom
Primary
Concomitant
Caesarean Section Other Serious Male 2 lb 4/9/2012 Consumer Japan
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 39 Male 220 lb 4/12/2012 Other Health Professional Japan
Primary
Concomitant
Interacting
Hypoxia Life Threatening 39 Male 220 lb 4/12/2012 Other Health Professional Japan
Primary
Concomitant
Interacting
Drug Interaction Life Threatening 39 Male 220 lb 4/12/2012 Other Health Professional Japan
Primary
Concomitant
Interacting
Cardiac Arrest Life Threatening 39 Male 4/17/2012 Other Health Professional Japan
Primary
Interacting
Blood Glucose Decreased Other Serious Male 2 lb 4/20/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious Female 115 lb 4/20/2012 Consumer Japan
Primary
Secondary
Concomitant
Drug Effect Decreased Other Serious 1/26/2012 55 Male 4/17/2012 Other Health Professional United Kingdom
Primary
Concomitant
Troponin Increased Required Intervention 49 Female 4/30/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 30 Male 5/29/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Postoperative Ileus Other Serious 4/4/2012 18 Male 199 lb 5/29/2012 Physician United States
Primary
Concomitant
Anosmia Disability 57 Female 5/23/2012 Physician United States
Primary
Concomitant
Stress Cardiomyopathy Hospitalization 30 Male 5/31/2012 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Life Threatening 39 Male 5/30/2012 Japan
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 220 lb 6/12/2012 Other Health Professional Japan
Primary
Interacting
Ventricular Tachycardia Life Threatening 30 Male 6/13/2012 Other Health Professional United States
Primary
Secondary
Electrocardiogram St Segment Elevation Hospitalization 30 Male 6/22/2012 Physician United States
Primary
Secondary
Concomitant
Glossoptosis Other Serious Male 220 lb 6/14/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Bradycardia Other Serious 2 Male 26 lb 6/29/2012 Turkey
Primary
Secondary
Concomitant
Postoperative Ileus Other Serious 4/4/2012 18 Male 199 lb 7/3/2012 Physician United States
Primary
Concomitant
Ventricular Tachycardia Death 4/18/2012 63 Female 154 lb 7/3/2012 Physician France
Primary
Secondary
Concomitant
Postoperative Ileus Hospitalization 4/4/2012 18 Male 199 lb 7/5/2012 Physician United States
Primary
Concomitant
Mitral Valve Incompetence Other Serious 30 Male 6/28/2012 Other Health Professional United States
Primary
Secondary
Immobile Other Serious 30 Male 7/20/2012 Pharmacist United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 17 Female 108 lb 8/3/2012 Physician United States
Primary
Concomitant
Intracranial Pressure Increased Other Serious 5/28/2009 1 Female 15 lb 3/8/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Renal Injury Other Serious 12/11/2005 76 Male 190 lb 3/14/2013 Other Health Professional Us
Primary
Concomitant
Renal Injury Other Serious 6/8/2003 81 Female 165 lb 3/9/2013 Physician Us
Primary
Concomitant
Drug Interaction Life Threatening 39 Male 220 lb 9/12/2012 Other Health Professional Jp
Primary
Secondary
Interacting
Pericardial Effusion Life Threatening 4/18/2011 55 Female 148 lb 2/27/2013 Other Health Professional Us
Primary
Concomitant
Hemiparesis Hospitalization 4/14/2007 51 Female 183 lb 9/4/2012 Other Health Professional Us
Primary
Concomitant
Stress Cardiomyopathy Other Serious 85 Female 77 lb 9/21/2012 Physician Jp
Primary
Secondary
Concomitant
Tremor Other Serious 10 Female 77 lb 10/6/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 2/5/2012 68 Female 11/8/2012 Consumer Jp
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/5/2012 68 Female 9/30/2013 Consumer Jp
Primary
Secondary
Concomitant
Movement Disorder Hospitalization 10 Female 10/10/2012 Other Health Professional Us
Primary
Secondary
Periodic Limb Movement Disorder Other Serious 10 Female 77 lb 10/4/2012 Physician Us
Primary
Secondary
Post Procedural Complication Other Serious 10 Female 11/7/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Disorientation Other Serious 80 Male 121 lb 12/14/2012 Physician Jp
Primary
Concomitant
Anaesthetic Complication Neurological Other Serious NotSpecified 1/15/2013 Other Health Professional De
Primary
Secondary
Concomitant
Decreased Activity Hospitalization NotSpecified 1/15/2013 Other Health Professional De
Primary
Secondary
Concomitant
Umbilical Cord Vascular Disorder Other Serious 32 Female 108 lb 2/18/2013 Other Health Professional Jp
Primary
Concomitant
Fear Of Death Other Serious 52 Male 2/19/2013 Physician Kr
Primary
Secondary
Concomitant
Syncope Life Threatening 12/18/2012 15 Female 3/1/2013 Physician Au
Primary
Secondary
Ventricular Extrasystoles Life Threatening 2/1/2012 66 Male 1/7/2013 Other Health Professional Jp
Primary
Concomitant
Pyrexia Other Serious 3/6/2013 41 Male 196 lb 4/1/2013 Other Health Professional Hu
Primary
Secondary
Concomitant
Hemiplegic Migraine Hospitalization 15 Male 152 lb 3/26/2013 Physician Au
Primary
Secondary
Concomitant
Fear Of Death Other Serious 52 Male 4/18/2013 Other Health Professional Kr
Primary
Secondary
Concomitant
Fear Of Death Other Serious 52 Male 3/28/2013 Physician Kr
Primary
Secondary
Concomitant
Fear Of Death Other Serious 52 Male 4/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Pulmonary Embolism Hospitalization 3 Male 29 lb 4/10/2013 Other Health Professional Es
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/31/2013 39 Female 132 lb 4/11/2013 Physician Gb
Primary
Secondary
Concomitant
Ventricular Hyperkinesia Other Serious 58 Female 5/13/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 71 Female 5/8/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Cough Other Serious 5/2011 25 Female 110 lb 5/17/2013 Physician Jp
Primary
Concomitant
Metabolic Acidosis Death 1 Male 15 lb 8/15/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Bronchospasm Hospitalization 12/19/2012 31 Female 198 lb 6/5/2013 Physician Gb
Primary
Concomitant
Anaphylactic Reaction Other Serious 12 Male 66 lb 6/26/2013 Other Health Professional Jp
Primary
Concomitant
Ileus Other Serious NotSpecified 6/17/2013 Physician Tr
Primary
Concomitant
Ileus Other Serious NotSpecified 6/17/2013 Physician Tr
Primary
Concomitant
Rash Other Serious 6/2013 55 Male 165 lb 7/30/2013 Physician Cn
Primary
Concomitant
Tremor Other Serious 6/2013 61 Female 121 lb 7/30/2013 Physician Cn
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 24 Male 7/1/2013 Other Health Professional Jo
Primary
Concomitant
Interacting
Mydriasis Other Serious 9/8/2009 50 Male 7/2/2013 Other Health Professional Fr
Primary
Secondary
Unresponsive To Stimuli Hospitalization 24 Male 7/7/2013 Other Health Professional Jo
Primary
Concomitant
Interacting
Serotonin Syndrome Hospitalization 24 Male 8/6/2013 Other Health Professional Jo
Primary
Secondary
Concomitant
Interacting
Serotonin Syndrome Hospitalization 24 Male 7/11/2013 Other Health Professional Jo
Primary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 24 Male 7/12/2013 Country Not Specified
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 39 Male 8/5/2013 Other Health Professional Us
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 39 Male 8/21/2013 Other Health Professional Us
Primary
Concomitant
Surgery Other Serious NotSpecified 9/11/2013 Physician Gr
Primary
Secondary
Status Epilepticus Hospitalization 5 Female 49 lb 9/5/2013 Other Health Professional Kr
Primary
Concomitant
Interacting
Carcinoid Crisis Hospitalization 68 Female 9/7/2013 Other Health Professional Gr
Primary
Secondary
Concomitant
Hypernatraemia Hospitalization 50 Female 227 lb 9/16/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Required Intervention 50 Female 227 lb 9/10/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Shock Other Serious 3 Male 9/23/2013 Other Health Professional Pl
Primary
Secondary
Concomitant

Drug Data