Midazolam combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatitis Hospitalization 10/23/2005 67 Female 1/25/2006 Other Health Professional Australia
Primary
Secondary
Dysuria Other Serious 11/11/2005 64 Male 1/25/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/9/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/9/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Nosocomial Infection Other Serious 10/6/2003 Male 240 lb 2/20/2006 Physician United States
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 12/1/2005 44 Female 3/15/2006 Consumer France
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 38 Male 220 lb 3/16/2006 Other Health Professional United States
Primary
Concomitant
Liver Disorder Required Intervention 12/28/2005 13 Female 79 lb 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Swelling Face Death 1/21/2003 14 Female 3/10/2006 Canada
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Female 3/27/2006 United Kingdom
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/29/2006 Spain
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/9/2006 18 Female 4/7/2006 Consumer France
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/11/2006 18 Female 4/10/2006
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Chills Other Serious 57 Male 128 lb 6/20/2006 Japan
Primary
Secondary
Resuscitation Life Threatening 7/14/2005 59 Female 183 lb 6/19/2006 Pharmacist United States
Primary
Concomitant
Shock Hospitalization 4/24/2006 51 Male 231 lb 6/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Chills Other Serious 10/18/2005 Male 128 lb 6/28/2006 Japan
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 6/30/2006 Physician
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2006 Male 7/12/2006 Other Health Professional Spain
Primary
Concomitant
Wheezing Life Threatening 3/11/2006 51 Female 8/11/2006 Consumer Australia
Primary
Secondary
Tachycardia Other Serious 4/8/2006 48 Female 8/12/2006 Australia
Primary
Secondary
Troponin I Increased Other Serious 12/1/2002 17 Female 9/11/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 8/22/2005 73 Female 170 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Ventricular Dysfunction Hospitalization 31 Female 11/16/2006 Consumer Canada
Primary
Secondary
Urticaria Other Serious 8/26/2005 76 Male 176 lb 11/15/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 31 Female 11/27/2006 Physician Canada
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Hypoxia Life Threatening 6/3/2006 Male 11/30/2006 Japan
Primary
Concomitant
Retinal Artery Occlusion Disability 49 Female 121 lb 11/30/2006 Physician China
Primary
Concomitant
Wound Secretion Other Serious 10/23/2006 67 Female 12/12/2006 Other Health Professional Australia
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 45 Male 7/19/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Erythema Other Serious 6/8/2007 41 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Erythema Life Threatening 6/8/2007 41 Female 8/2/2007 United Kingdom
Primary
Secondary
Laryngospasm Other Serious 6/8/2007 41 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Oxygen Saturation Decreased 35 Male 10/8/2007 Other Health Professional Australia
Primary
Secondary
Ulcer Other Serious 75 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 75 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Swollen Tongue Other Serious 70 Female 86 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Life Threatening 4/30/2007 69 Male 165 lb 10/25/2007 Other Health Professional Australia
Primary
Secondary
Toxic Epidermal Necrolysis Death 53 Female 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/28/2008 Poland
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 7/30/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/30/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/1/2008 Poland
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/22/2008 Poland
Primary
Concomitant
Skin Ulcer Hospitalization 9/8/2008 Female 136 lb 9/12/2008 United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/23/2007 41 Female 9/10/2008 Other Health Professional New Zealand
Primary
Concomitant
Toxic Encephalopathy Required Intervention 49 Female 9/22/2008 Canada
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 Male 187 lb 9/25/2008 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/19/2008 Male 9/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 5/1/1998 0 Female 11 lb 10/13/2008 Physician Austria
Primary
Secondary
Concomitant
Overdose Other Serious 9/5/2008 66 Male 12/2/2008 Physician Germany
Primary
Concomitant
Resuscitation Life Threatening 24 Female 163 lb 12/9/2008 Physician Pakistan
Primary
Secondary
Concomitant
Completed Suicide Death 41 Male 1/5/2009 Pharmacist United States
Primary
Secondary
Lactic Acidosis Other Serious 6/13/2006 43 Female 1/6/2009 Other Health Professional Chile
Primary
Concomitant
Extrapyramidal Disorder Other Serious 8/12/2008 52 Male 156 lb 1/7/2009 Other Health Professional United States
Primary
Concomitant
Arteriospasm Coronary Life Threatening 60 Female 119 lb 3/26/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 51 Male 192 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/2/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/15/2009 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Other Serious 60 Female 11/12/2009 Other Health Professional France
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 14 Female 12/23/2009 Australia
Primary
Concomitant
Procedural Vomiting Other Serious 6/1/2008 52 Female 108 lb 2/19/2010
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 67 Female 99 lb 3/2/2010 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 2/2/2010 24 Male 5/26/2010 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 2/2/2010 24 Male 6/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 6/10/2010 Physician United States
Primary
Concomitant
Interacting
Anaphylactic Reaction Other Serious 5/17/2010 57 Male 6/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2008 65 Male 258 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 3/21/2007 Female 9 lb 6/17/2010 Physician United States
Primary
Secondary
International Normalised Ratio Increased Disability 1/5/2010 75 Male 7/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 7/14/2010 26 Female 176 lb 7/26/2010 Physician Portugal
Primary
Concomitant
Ulcer Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/31/2010 19 Male 198 lb 10/9/2010 United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/1/2002 75 Female 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 19 Female 165 lb 10/22/2010
Primary
Secondary
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anticholinergic Syndrome Hospitalization 28 Female 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Anticholinergic Syndrome Hospitalization 28 Female 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Anticholinergic Syndrome Hospitalization 28 Female 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 10/27/2010 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 6/25/2009 49 Male 10/29/2010 Consumer United States
Primary
Secondary
Renal Failure Other Serious 1/1/2002 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2002 75 Female 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/1/2002 75 Female 11/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 4/13/2010 59 Male 11/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 11/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 42 Male 11/8/2010 Other Health Professional Switzerland
Primary
Secondary
Interacting
Vomiting Other Serious 11/3/2003 47 Male 180 lb 11/8/2010 United States
Primary
Concomitant
Acute Hepatic Failure Life Threatening 10/2/2010 3 Male 33 lb 10/27/2010 Netherlands
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 4/13/2010 59 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Tachypnoea Other Serious 24 Male 11/16/2010
Primary
Secondary
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 11/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 31 Male 11/19/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 5/27/2010 74 Male 163 lb 11/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Foetal Growth Restriction Other Serious 11/23/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Life Threatening 49 Female 11/29/2010 Other Health Professional Austria
Primary
Concomitant
Interacting
Oligohydramnios Other Serious 20 Female 132 lb 11/29/2010 Pharmacist United States
Primary
Secondary
Stridor Hospitalization Female 11/29/2010 Physician Australia
Primary
Secondary
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 9 Female 73 lb 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/7/2010 34 Female 141 lb 12/14/2010 Other Health Professional Indonesia
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/7/2010 34 Female 141 lb 12/15/2010 Other Health Professional Indonesia
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 5/27/2010 74 Male 163 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/20/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 45 Female 134 lb 12/20/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Pulmonary Embolism Death 23 Female 12/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Shock Life Threatening 11/25/2010 64 Female 12/21/2010 Physician France
Primary
Secondary
Concomitant
Tachycardia Other Serious 74 Female 12/24/2010 Other Health Professional France
Primary
Secondary

Drug Data