Midazolam combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Hospitalization 10/1/2005 Female 1/4/2006 Consumer United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 10/22/2005 86 Female 223 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
Multi-organ Failure Death 1/1/2005 72 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/29/2006 Spain
Primary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/9/2006 18 Female 4/7/2006 Consumer France
Primary
Secondary
Concomitant
Removal Of Foreign Body From Oesophagus Other Serious 1/18/1997 1 Male 20 lb 4/7/2006 Physician United States
Primary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/11/2006 18 Female 4/10/2006
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 6/30/2006 Physician
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2006 Male 7/12/2006 Other Health Professional Spain
Primary
Concomitant
Myoglobinuria Hospitalization 11/14/2005 68 Male 143 lb 11/1/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Toxic Shock Syndrome Hospitalization 1/1/2004 27 Male 10/24/2006 Physician Netherlands
Primary
Concomitant
Hepatitis Other Serious 63 Male 11/14/2006 Pharmacist Canada
Primary
Concomitant
Hepatitis Other Serious 63 Male 11/15/2006 Pharmacist Canada
Primary
Concomitant
Thrombosis Death 42 Male 176 lb 11/24/2006 Pharmacist Canada
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Life Support Death 2/22/2002 28 Female 88 lb 11/17/2006 Other Health Professional France
Primary
Secondary
Wound Infection Life Threatening 1/14/2007 Male 353 lb 8/2/2007 Physician Australia
Primary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2000 71 Female 10/20/2007 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/28/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/30/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/1/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/22/2008 Poland
Primary
Concomitant
Respiratory Rate Increased Other Serious 6/25/2008 33 Male 9/17/2008 Ireland
Primary
Concomitant
Respiratory Rate Increased Other Serious 6/23/2008 30 Male 9/17/2008 Ireland
Primary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Disorder Other Serious 10/16/2007 Male 205 lb 10/7/2008 Physician Italy
Primary
Concomitant
Cholestasis Hospitalization 9/7/2008 49 Female 10/17/2008 Other Health Professional France
Primary
Concomitant
Stillbirth Other Serious 20 Female 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Extrapyramidal Disorder Other Serious 8/12/2008 52 Male 156 lb 1/7/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 4/10/2009 Physician Netherlands
Primary
Concomitant
Interacting
Cholestasis Hospitalization 9/7/2008 49 Female 6/5/2009 Other Health Professional France
Primary
Concomitant
Cardiac Valve Disease Other Serious 5/15/2009 63 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Other Serious 26 7/9/2009 Other Health Professional India
Primary
Concomitant
Acute Hepatic Failure Other Serious 1/17/2010 57 Male 195 lb 3/25/2010 Pharmacist Canada
Primary
Concomitant
Oncologic Complication Hospitalization 5/3/2010 75 Female 6/10/2010 Portugal
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2007 68 Male 159 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2008 43 Male 7/14/2010 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 7/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vascular Graft Thrombosis Other Serious Male 8/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Ischaemic Stroke Other Serious 4/6/2010 50 Male 128 lb 10/15/2010 Physician France
Primary
Concomitant
Renal Impairment Hospitalization 4/9/2008 61 Female 108 lb 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 19 Female 165 lb 10/22/2010
Primary
Secondary
Vomiting Other Serious 11/3/2003 47 Male 180 lb 10/27/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/29/2010 Pharmacist Japan
Primary
Secondary
Pancytopenia Death 9/25/2010 84 Male 19 lb 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/25/2010 84 Male 187 lb 11/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 42 Male 11/8/2010 Other Health Professional Switzerland
Primary
Secondary
Interacting
Vomiting Other Serious 11/3/2003 47 Male 180 lb 11/8/2010 United States
Primary
Concomitant
Wound Dehiscence Other Serious 10/1/2007 68 Male 159 lb 11/9/2010 Lawyer United States
Primary
Concomitant
Pneumonia Staphylococcal Other Serious 1/1/2008 0 Male 4 lb 11/10/2010 Other Health Professional United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 11/2/2010 Japan
Primary
Secondary
Haematemesis Life Threatening 6/23/2010 8 Male 37 lb 11/15/2010 Physician Thailand
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 21 Female 11/16/2010
Primary
Secondary
Thrombocytopenia Other Serious Female 11/29/2010 Physician Australia
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Tachycardia Death 11/21/2008 66 Female 143 lb 11/30/2010 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Neonatal Other Serious 10/25/2010 Male 3 lb 12/1/2010 Physician United Kingdom
Primary
Concomitant
Rash Generalised 10/7/2010 50 Female 11/23/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 9 Female 73 lb 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 43 Male 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Pleural Effusion Other Serious 9/10/2010 53 Female 243 lb 11/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 11/16/2010 14 Female 130 lb 12/17/2010 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 1/6/2011 79 Male 150 lb 1/18/2011 Physician Chile
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 1/20/2011 Physician Thailand
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Death 7/1/2007 1 Male 18 lb 1/27/2011 Physician United States
Primary
Concomitant
Ischaemic Stroke Death 4/6/2010 50 Male 128 lb 1/26/2011 Physician France
Primary
Concomitant
Death Death 1/30/2011 51 Female 110 lb 3/10/2011 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 1/30/2011 51 Female 110 lb 3/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/1/2008 59 Male 3/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 1/30/2011 51 Female 110 lb 3/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 5/1/2008 65 Male 254 lb 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 5/1/2008 59 Male 194 lb 3/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 3/24/2011 Physician Thailand
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 12/1/2010 51 Female 110 lb 3/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 2/21/2011 58 Female 4/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 12/1/2010 51 Female 110 lb 4/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Hospitalization 2/21/2011 58 Female 4/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 6/23/2010 8 Male 35 lb 4/12/2011 Physician Thailand
Primary
Secondary
Concomitant
Hypotension Death 12/1/2010 51 Female 110 lb 4/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 4/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stress Other Serious 10/8/2001 22 Male 209 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 3/2/2011 41 Female 220 lb 4/19/2011 Physician Poland
Primary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 12/1/2010 71 Female 127 lb 4/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Anxiety Other Serious 5/14/2006 59 Female 170 lb 4/28/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 3/18/2002 1 Male 11 lb 4/29/2011 Consumer United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 5/5/2011 Other Health Professional China
Primary
Secondary
Concomitant
Emotional Distress Other Serious 1/1/2006 82 Male 149 lb 5/11/2011 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious Female 5/12/2011 New Zealand
Primary
Concomitant
Disease Progression Hospitalization 2/21/2011 58 Female 5/24/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 2/14/2011 74 Female 137 lb 5/23/2011 Pharmacist United States
Primary
Concomitant
Panic Attack Other Serious 4/1/2011 42 Female 5/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Psychiatric Symptom Hospitalization 8/1/2006 80 Female 185 lb 6/4/2011 Consumer United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 12/18/2001 38 Male 179 lb 6/7/2011 Lawyer United States
Primary
Concomitant
Hypotension Other Serious 4/2/2011 52 Male 176 lb 6/16/2011 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/22/2011 53 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/8/2007 54 Female 11/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Periodontitis Other Serious 1/1/1998 36 Female 172 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 1/8/2007 54 Female 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 12/1/2010 51 Female 110 lb 11/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoxic-ischaemic Encephalopathy Death 10/22/2011 48 Male 190 lb 11/10/2011 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 12/1/2010 51 Female 110 lb 11/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 12/1/2010 51 Female 110 lb 11/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/3/2011 11/16/2011 Physician Australia
Primary
Concomitant
Bronchospasm Other Serious 1/1/1998 36 Female 172 lb 11/17/2011 Consumer United States
Primary
Secondary
Concomitant
Lipase Increased Death 5/17/2011 69 Female 121 lb 11/22/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pulmonary Hypertension Disability 12/1/2010 51 Female 110 lb 11/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 50 Male 11/17/2011 United Kingdom
Primary
Concomitant
Joint Abscess Hospitalization 8/4/2011 63 Male 141 lb 11/29/2011 Consumer United States
Primary
Secondary
Concomitant
Anhedonia Other Serious 3/21/2004 73 Male 220 lb 11/30/2011 Lawyer United States
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Other Serious 66 Female 12/8/2011 Other Health Professional United States
Primary
Concomitant
Depression Hospitalization 56 Male 300 lb 11/23/2011 Lawyer United States
Primary
Concomitant
Crohn's Disease Hospitalization 11/25/2011 11 Female 81 lb 12/16/2011 Physician United States
Primary
Secondary
Concomitant
Otitis Media Acute Hospitalization 1/1/1998 36 Female 172 lb 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Sinusitis Hospitalization 1/1/1998 36 Female 172 lb 12/29/2011 Consumer United States
Primary
Secondary
Concomitant
Impaired Gastric Emptying Other Serious 1/1/1998 36 Female 172 lb 1/1/2012 Physician United States
Primary
Secondary
Concomitant
Exostosis Other Serious 1/1/1998 36 Female 172 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Influenza Death 54 Male 198 lb 1/5/2012 Spain
Primary
Concomitant
Sedation Hospitalization 12/27/2011 67 Male 249 lb 1/11/2012 Physician Netherlands
Primary
Concomitant
Blood Bilirubin Increased Death 5/17/2011 69 Female 121 lb 1/12/2012 Physician Korea, Republic Of
Primary
Secondary
Concomitant

Drug Data