Midazolam Hcl combined with Vecuronium Bromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Required Intervention 11/27/2005 64 Male 2/24/2006 Pharmacist Japan
Primary
Concomitant
Wheezing Hospitalization 11/19/2005 Female 44 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Neonatal Tachypnoea Other Serious 7/6/2005 0 Male 3/8/2006 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 11/27/2005 64 Male 4/12/2006 Pharmacist Japan
Primary
Concomitant
Multi-organ Failure Death 34 Female 190 lb 4/21/2006 Physician Turkey
Primary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 4/19/2006 United States
Primary
Concomitant
Spleen Disorder Hospitalization 11/29/2005 76 Male 5/19/2006 Other Health Professional Japan
Primary
Concomitant
Tachycardia Required Intervention 38 Male 5/22/2006 Physician Japan
Primary
Concomitant
Thyrotoxic Crisis Other Serious 74 Female 6/5/2006 Physician Japan
Primary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Obstructive Airways Disorder Hospitalization 4/30/2006 80 Male 6/2/2006 Japan
Primary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 6/6/2006 United States
Primary
Concomitant
Respiratory Acidosis Life Threatening 32 Male 6/7/2006 India
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Cerebral Infarction Life Threatening 3/28/2006 71 Female 6/19/2006 Other Health Professional Japan
Primary
Concomitant
Skin Irritation Other Serious 7/22/2005 0 Male 6/6/2006 Japan
Primary
Concomitant
Hypoxic Encephalopathy Death 35 Male 154 lb 10/19/2006 Other Health Professional Japan
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 15 Female 10/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/5/2007 Physician Australia
Primary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/13/2007 Physician Australia
Primary
Concomitant
Ventricular Fibrillation Other Serious 60 Male 2/17/2007 Japan
Primary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/26/2007 Physician Australia
Primary
Concomitant
Hypoacusis Disability 2/1/2002 2 Female 3/2/2007 Japan
Primary
Concomitant
Pulmonary Hypertension Disability 11/1/2004 1 Female 3/2/2007 Japan
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 3/9/2007 Physician Australia
Primary
Concomitant
Multi-organ Failure Disability 11/1/2004 1 Female 3/6/2007 Japan
Primary
Concomitant
Tracheostomy 11 Male 3/12/2007 Japan
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 4/11/2007 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 4/3/2007 59 Female 187 lb 4/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sinobronchitis Other Serious 31 Male 185 lb 4/19/2007
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 4/23/2007 Physician Australia
Primary
Concomitant
Hyperthermia Malignant Other Serious 4/11/2007 Male 159 lb 4/26/2007 Other Health Professional Japan
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/1/2007 Physician Australia
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/14/2007 Physician Australia
Primary
Concomitant
Wheezing Disability 4/5/2007 74 Male 160 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/29/2007 Physician Australia
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/29/2007 Physician Australia
Primary
Concomitant
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Coagulopathy Death 2/15/2007 Male 220 lb 7/16/2007 Physician Australia
Primary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 76 Male 8/17/2007 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Other Serious 2 Female 32 lb 8/17/2007
Primary
Secondary
Concomitant
No Therapeutic Response Life Threatening 48 Female 9/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Failure Other Serious 78 Female 9/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulse Absent Other Serious 2 Female 31 lb 10/8/2007
Primary
Secondary
Pulse Absent Other Serious 2 Female 31 lb 10/12/2007
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 15 Female 44 lb 10/16/2007 Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 5/14/2007 18 Male 180 lb 10/24/2007 United States
Primary
Concomitant
Femoral Pulse Decreased Other Serious 1/1/2007 2 Female 32 lb 11/14/2007 Physician United States
Primary
Secondary
Drug Effect Decreased Other Serious 58 Female 11/30/2007
Primary
Concomitant
Opisthotonus Other Serious 11/1/2006 20 Female 117 lb 12/7/2007 Other Health Professional China
Primary
Concomitant
Interacting
Quadriplegia Female 12/12/2007 Physician Japan
Primary
Secondary
Pulmonary Oedema Life Threatening 1/30/2007 0 Female 7 lb 1/25/2008 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 67 Male 146 lb 2/14/2008 Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 1/30/2007 0 Female 7 lb 2/19/2008 Physician Japan
Primary
Concomitant
Inhibitory Drug Interaction 41 Male 2/12/2008 India
Primary
Secondary
Concomitant
Asthma 49 Female 4/2/2008 Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/13/2008 Other Health Professional Japan
Primary
Concomitant
Hyperamylasaemia Other Serious 3/5/2004 55 Male 5/15/2008 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/21/2008 Other Health Professional Japan
Primary
Concomitant
Pyogenic Granuloma Other Serious 5/28/2008 Other Health Professional Spain
Primary
Secondary
Cardiac Arrest Life Threatening 36 Female 115 lb 6/24/2008 Physician Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 76 Female 6/25/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/17/2008 1 Male 19 lb 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 7/10/2008 Japan
Primary
Secondary
Septic Shock Death 6/15/2008 Male 84 lb 7/10/2008 Korea, Republic Of
Primary
Concomitant
Toxic Epidermal Necrolysis Death 53 Female 7/18/2008 Consumer Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 7/21/2008 Japan
Primary
Secondary
Rectal Cancer Other Serious 7/1/2007 59 Male 7/22/2008 Norway
Primary
Concomitant
Toxic Epidermal Necrolysis Death 9/16/2005 Female 121 lb 7/23/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 53 Female 7/28/2008 Consumer Japan
Primary
Secondary
Serotonin Syndrome Hospitalization 1/1/2007 25 Male 7/31/2008 Physician Turkey
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 7/31/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 9/16/2005 Female 126 lb 8/8/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 8/13/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 9/16/2005 Female 126 lb 8/20/2008 Japan
Primary
Secondary
Tryptase Increased Life Threatening 6/1/2008 38 Female 187 lb 9/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 10/19/2007 7 Male 37 lb 9/11/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2007 22 Male 112 lb 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Sedation Other Serious 83 Female 10/17/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2007 22 Male 112 lb 10/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 8/25/2008 Male 154 lb 11/12/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 10/19/2007 7 Male 37 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 8/25/2008 Male 11/20/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 8/6/2007 73 Male 154 lb 11/20/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/25/2008 Male 154 lb 11/26/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Nervous System Disorder Death 0 Female 11/20/2008 Netherlands
Primary
Concomitant
Post Procedural Complication Other Serious 5/15/2008 87 Female 139 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Coagulopathy Death 2/15/2007 Male 220 lb 12/1/2008 Physician Australia
Primary
Concomitant
Tachypnoea Hospitalization 2 Male 20 lb 11/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 60 Male 12/4/2008 Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/29/2008 78 Female 110 lb 11/26/2008 Pharmacist United States
Primary
Concomitant
Tachypnoea Hospitalization 2 Male 20 lb 11/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Tryptase Increased Life Threatening 6/1/2008 38 Female 187 lb 12/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Death 12/12/2008 Other Health Professional Canada
Primary
Secondary
Postoperative Fever Other Serious 3/12/2008 Male 1/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 168 lb 1/15/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Function Test Decreased Other Serious 20 Female 1/23/2009 Physician United States
Primary
Secondary
Heart Rate Increased Other Serious 74 Female 2/16/2009 Physician Japan
Primary
Secondary
Ventricular Extrasystoles Life Threatening 30 Female 128 lb 2/25/2009 Physician Japan
Primary
Secondary
Rhabdomyolysis Life Threatening 1 Male 3/6/2009 Japan
Primary
Secondary
Concomitant
Anaphylactoid Reaction Life Threatening 2/9/2009 61 Male 3/9/2009 United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2008 30 Female 128 lb 3/18/2009 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 3/20/2009 Japan
Primary
Secondary
Concomitant
Arteriospasm Coronary Life Threatening 60 Female 119 lb 3/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 60 Female 119 lb 3/23/2009
Primary
Secondary
Ventricular Tachycardia Life Threatening 60 Female 3/31/2009 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Death 67 Female 4/10/2009 United Kingdom
Primary
Secondary
Concomitant
Arteriospasm Coronary Life Threatening 11/29/1998 60 Female 119 lb 4/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 52 Female 137 lb 4/27/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Required Intervention 4/17/2009 Female 147 lb 4/30/2009 Other Health Professional United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/19/2009 Male 203 lb 5/20/2009 Consumer United States
Primary
Secondary
Concomitant
Ecg Signs Of Myocardial Ischaemia Hospitalization 47 Female 152 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 6/3/2009 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Aspiration 38 Male 6/5/2009 Japan
Primary
Concomitant
Respiration Abnormal 38 Male 6/9/2009 Physician Japan
Primary
Concomitant
Urticaria Life Threatening 5/11/2009 76 Female 143 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Life Threatening 5/11/2009 76 Female 143 lb 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2007 Female 16 lb 7/1/2009 Japan
Primary
Secondary
Concomitant
Urticaria Life Threatening 5/11/2009 76 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nodal Rhythm Other Serious 9 Male 44 lb 7/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pharyngeal Oedema Death 6/23/2009 3 Male 26 lb 8/5/2009 Physician China
Primary
Concomitant
Respiratory Failure Hospitalization 9/10/2007 Female 16 lb 8/6/2009 Japan
Primary
Secondary
Concomitant
Nodal Rhythm Other Serious 9 Male 44 lb 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7/30/2009 59 Female 128 lb 8/12/2009 Physician Mexico
Primary
Concomitant
Tachycardia Other Serious 52 Female 137 lb 8/18/2009
Primary
Secondary
Anaphylactic Shock Other Serious 10/11/2004 35 Female 190 lb 8/20/2009 Other Health Professional China
Primary
Concomitant
Drug Ineffective Other Serious 7/30/2009 59 Female 128 lb 8/24/2009 Physician Mexico
Primary
Concomitant
Drug Interaction Other Serious 33 Female 176 lb 8/27/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 52 Female 137 lb 8/28/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/10/2007 Female 16 lb 9/4/2009 Japan
Primary
Secondary
Concomitant
Retinopathy Of Prematurity Other Serious 5/10/2005 Male 4 lb 9/16/2009 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 76 Female 9/16/2009 Other Health Professional Japan
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 3/29/2008 0 Male 7 lb 9/24/2009 Physician United States
Primary
Concomitant
Drug Effect Decreased Other Serious 1/20/2009 55 Male 258 lb 9/22/2009 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 7/1/2007 56 Female 10/29/2009 Lawyer United States
Primary
Concomitant
Anaphylactic Reaction Death 10/20/2009 Female 11/12/2009 Pharmacist Australia
Primary
Concomitant
Anaphylactic Reaction Death 10/20/2009 62 Female 11/19/2009 Pharmacist Australia
Primary
Concomitant
Rhabdomyolysis Other Serious 2/8/2006 Male 168 lb 11/19/2009 Japan
Primary
Concomitant
Urticaria Life Threatening 5/11/2009 76 Female 143 lb 12/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Life Threatening 5/11/2009 76 Female 12/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Life Threatening 5/11/2009 76 Female 12/10/2009 United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Death 10/20/2009 62 Female 12/21/2009 Pharmacist Australia
Primary
Concomitant
Death Death 7/9/2009 1 Male 7 lb 1/15/2010 Physician Japan
Primary
Concomitant
Wound Secretion Hospitalization 11/16/2009 75 Male 161 lb 1/26/2010 Physician Germany
Primary
Concomitant

Drug Data