Midazolam Hcl combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Renal Impairment Required Intervention 5/25/2005 68 Male 149 lb 3/1/2006 Physician Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 8 Male 64 lb 3/9/2006 France
Primary
Concomitant
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Mental Status Changes Life Threatening 6/14/2004 49 Female 3/14/2006 United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 11/27/2005 64 Male 4/12/2006 Pharmacist Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 91 Male 137 lb 4/21/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 30 Male 161 lb 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 4/19/2006 United States
Primary
Concomitant
Rash Other Serious 4/13/2006 52 Male 190 lb 5/10/2006 Consumer United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 8 Male 64 lb 5/12/2006 Physician France
Primary
Concomitant
Somatosensory Evoked Potentials Abnormal Other Serious 7 Female 97 lb 5/20/2006 Australia
Primary
Concomitant
Tachycardia Required Intervention 38 Male 5/22/2006 Physician Japan
Primary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 43 Male 216 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Priapism Other Serious 17 Male 6/9/2006 Other Health Professional United States
Primary
Concomitant
Procedural Complication Required Intervention 7 Female 97 lb 6/2/2006 Physician Australia
Primary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 6/6/2006 United States
Primary
Concomitant
Proteinuria Hospitalization 5/30/2006 8 Male 6/14/2006 Other Health Professional Japan
Primary
Secondary
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Cerebral Infarction Life Threatening 3/28/2006 71 Female 6/19/2006 Other Health Professional Japan
Primary
Concomitant
Nerve Root Compression Other Serious 7 Female 97 lb 7/6/2006
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 8 Male 9/14/2006 Physician France
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 15 Female 10/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Atelectasis Required Intervention 22 Male 99 lb 1/3/2007 Physician Japan
Primary
Concomitant
Surgery Other Serious 69 Female 1/23/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Endotracheal Intubation Complication Required Intervention 22 Male 99 lb 1/17/2007 Physician Japan
Primary
Concomitant
Myoclonic Epilepsy Other Serious 3 Male 1/30/2007 France
Primary
Concomitant
Atelectasis Required Intervention 22 Male 99 lb 1/29/2007 Physician Japan
Primary
Concomitant
Tracheostomy 11 Male 3/12/2007 Japan
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Sinobronchitis Other Serious 31 Male 185 lb 4/19/2007
Primary
Secondary
Concomitant
Hyperthermia Malignant Other Serious 4/11/2007 Male 159 lb 4/26/2007 Other Health Professional Japan
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Post Procedural Complication Hospitalization 73 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 79 Female 110 lb 7/11/2007 Physician United States
Primary
Concomitant
Interacting
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 76 Male 8/17/2007 Other Health Professional Japan
Primary
Concomitant
Myocarditis Hospitalization 5/29/2007 34 Female 8/21/2007 Other Health Professional France
Primary
Secondary
Respiratory Arrest Life Threatening 6/13/2007 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/13/2007 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 2 Male 29 lb 10/5/2007 Physician Japan
Primary
Concomitant
Right Atrial Pressure Increased Hospitalization 33 Female 10/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 15 Female 44 lb 10/16/2007 Japan
Primary
Concomitant
Pneumonia Aspiration Hospitalization 2 Male 29 lb 10/23/2007 Physician Japan
Primary
Concomitant
Respiratory Distress Hospitalization 11/9/2007 Physician New Zealand
Primary
Concomitant
Respiratory Depression Life Threatening 53 Female 128 lb 11/19/2007
Primary
Secondary
Concomitant
Respiratory Depression Required Intervention 3/9/2007 11/27/2007 Pharmacist United States
Primary
Concomitant
Respiratory Depression Other Serious 53 Female 128 lb 1/18/2008 New Zealand
Primary
Concomitant
Pco2 Decreased Other Serious 76 Female 1/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 58 Female 1/29/2008 Physician New Zealand
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 67 Male 146 lb 2/14/2008 Japan
Primary
Concomitant
Hepatitis Other Serious 76 Female 119 lb 2/15/2008 Germany
Primary
Concomitant
Serotonin Syndrome Other Serious 58 Female 2/12/2008 New Zealand
Primary
Secondary
Concomitant
Tachycardia Other Serious 58 Female 2/20/2008 New Zealand
Primary
Concomitant
Pco2 Decreased Other Serious 2/10/1999 76 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 58 Female 3/10/2008
Primary
Secondary
Concomitant
Pulse Absent Death 2/10/1999 76 Female 3/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Staring 2/12/2008 4 3/14/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 5 3/14/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 9 3/14/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 4 3/14/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 4 3/14/2008 Pharmacist France
Primary
Concomitant
Agitation 2/12/2008 60 Male 3/14/2008 Pharmacist France
Primary
Concomitant
Procedural Complication Death 76 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Death 2/10/1999 76 Female 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Staring 2/12/2008 3 Male 35 lb 3/25/2008 Pharmacist France
Primary
Concomitant
Agitation 2/12/2008 5 Male 53 lb 3/25/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 9 Male 57 lb 3/25/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 5 Female 44 lb 3/25/2008 Pharmacist France
Primary
Concomitant
Panic Reaction 2/12/2008 59 Male 152 lb 3/25/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 3 Male 3/25/2008 Pharmacist France
Primary
Concomitant
Toxic Encephalopathy Hospitalization 49 Female 4/17/2008 Physician Canada
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 47 Male 4/24/2008 Other Health Professional Australia
Primary
Concomitant
Migraine With Aura Other Serious 15 Male 152 lb 4/30/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/13/2008 Other Health Professional Japan
Primary
Concomitant
Hyperamylasaemia Other Serious 3/5/2004 55 Male 5/15/2008 Physician Japan
Primary
Concomitant
Staring 2/12/2008 3 Male 35 lb 5/16/2008 Pharmacist France
Primary
Concomitant
Agitation 2/12/2008 5 Male 53 lb 5/16/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 9 Male 57 lb 5/16/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 5 Female 44 lb 5/16/2008 Pharmacist France
Primary
Concomitant
Staring 2/12/2008 3 Male 5/16/2008 Pharmacist France
Primary
Concomitant
Panic Reaction 2/12/2008 59 Male 152 lb 5/16/2008 Pharmacist France
Primary
Concomitant
Haematocrit Decreased Hospitalization 7/20/2007 71 Male 5/20/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/21/2008 Other Health Professional Japan
Primary
Concomitant
Hyperaesthesia Other Serious 46 Female 139 lb 5/30/2008 Spain
Primary
Secondary
Concomitant
Migraine With Aura Hospitalization 15 Male 152 lb 6/6/2008 Australia
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 76 Female 6/25/2008 Physician Japan
Primary
Concomitant
Sepsis Death 3/26/2007 66 Male 176 lb 6/27/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Staring Other Serious 2/12/2008 3 Male 35 lb 6/27/2008 Pharmacist France
Primary
Concomitant
Agitation Other Serious 2/12/2008 5 Male 53 lb 6/27/2008 Pharmacist France
Primary
Concomitant
Staring Other Serious 2/12/2008 9 Male 57 lb 6/27/2008 Pharmacist France
Primary
Concomitant
Staring Other Serious 2/12/2008 5 Female 44 lb 6/27/2008 Pharmacist France
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/3/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vision Blurred Other Serious 29 Male 7/1/2008 Physician Mexico
Primary
Concomitant
Hyperthermia Malignant Other Serious Male 132 lb 7/8/2008 Romania
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 7/10/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 53 Female 7/18/2008 Consumer Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 7/21/2008 Japan
Primary
Secondary
Rectal Cancer Other Serious 7/1/2007 59 Male 7/22/2008 Norway
Primary
Concomitant
Toxic Epidermal Necrolysis Death 9/16/2005 Female 121 lb 7/23/2008 Japan
Primary
Secondary
Ventricular Failure Death 1 9 lb 7/24/2008 Physician Brazil
Primary
Concomitant
Toxic Epidermal Necrolysis Death 53 Female 7/28/2008 Consumer Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 7/31/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 9/16/2005 Female 126 lb 8/8/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 8/13/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 9/16/2005 Female 126 lb 8/20/2008 Japan
Primary
Secondary
Spinal Fracture Other Serious 12/4/2006 Female 119 lb 8/29/2008 Physician United States
Primary
Concomitant
Cerebrovascular Accident Death 9/5/2008
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/28/2008 9/16/2008 Pharmacist United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/26/2008 83 Male 139 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Overdose Other Serious 9/24/2008 13 Female 10/6/2008 Physician France
Primary
Secondary
Sedation Other Serious 83 Female 10/17/2008 Japan
Primary
Secondary
Concomitant
Tenotomy Other Serious 16 Male 90 lb 10/27/2008 Other Health Professional Oman
Primary
Concomitant
Interacting
Wheezing Required Intervention 1 Female 20 lb 10/28/2008 Physician United States
Primary
Concomitant
Tracheomalacia Other Serious 14 Female 11/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 8/26/2008 83 Male 139 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/25/2008 79 Male 134 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Hemiparesis Other Serious 9/2/2008 81 Female 101 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Tachypnoea Hospitalization 2 Male 20 lb 11/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 60 Male 12/4/2008 Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/29/2008 78 Female 110 lb 11/26/2008 Pharmacist United States
Primary
Concomitant
Tachypnoea Hospitalization 2 Male 20 lb 11/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 2 Female 12/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Anaesthetic Complication Other Serious 11/17/2008 30 Female 112 lb 12/11/2008 Physician Japan
Primary
Concomitant
Panic Reaction Other Serious 2/12/2008 59 Male 152 lb 12/12/2008 Pharmacist France
Primary
Concomitant
Circulatory Collapse Hospitalization 2 Female 23 lb 12/15/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Circulatory Collapse Life Threatening 2 Female 23 lb 12/15/2008 Canada
Primary
Secondary
Concomitant
Bronchospasm Other Serious 1 Female 20 lb 12/16/2008
Primary
Secondary
Concomitant
Hallucination, Visual Other Serious 12/19/2008 Physician Japan
Primary
Secondary
Concomitant
Electromechanical Dissociation Other Serious 2 Female 12/16/2008 Canada
Primary
Secondary
Concomitant
Postoperative Fever Other Serious 3/12/2008 Male 1/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatitis Acute Death 6 Male 2/9/2009 Physician Australia
Primary
Secondary
Threatened Labour Hospitalization 6/22/2008 40 Female 2/6/2009 Japan
Primary
Secondary
Concomitant
Dystonia Other Serious 1/22/2009 17 Male 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 74 Female 2/16/2009 Physician Japan
Primary
Secondary
Dystonia Other Serious 1/22/2009 17 Male 2/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dystonia Other Serious 1/22/2009 17 Male 2/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Anaphylactic Shock Life Threatening 5/29/2008 42 Male 3/2/2009 Other Health Professional France
Primary
Secondary
Dystonia Other Serious 1/22/2009 17 Male 2/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 30 Female 128 lb 2/25/2009 Physician Japan
Primary
Secondary

Drug Data