Midazolam Hcl combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Other Serious 24 Female 123 lb 1/3/2006 United States
Primary
Secondary
Concomitant
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/9/2005 75 Male 176 lb 1/12/2006 Physician Japan
Primary
Concomitant
Anaphylactic Shock Life Threatening 5/24/2004 24 Female 106 lb 10/6/2005 Physician France
Primary
Concomitant
Acute Myocardial Infarction Other Serious 12/19/2005 58 Male 106 lb 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malignant Hypertension Life Threatening 9/20/2004 46 Female 2/2/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Liver Disorder 12/28/2005 13 Female 2/3/2006 Physician Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/9/2005 75 Male 176 lb 2/6/2006 Physician Japan
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 23 Female 205 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 6/23/2005 52 Male 220 lb 2/8/2006 Other Health Professional France
Primary
Secondary
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 75 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2006 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 19 Male 67 lb 2/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 22 Male 56 lb 2/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 5/25/2005 68 Male 149 lb 3/1/2006 Physician Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 8 Male 64 lb 3/9/2006 France
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Unknown 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Circulatory Collapse Disability 1/31/2006 41 Female 3/2/2006 United Kingdom
Primary
Concomitant
Metabolic Acidosis Death 24 Female 121 lb 3/10/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/7/2006 Spain
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 32 Female 132 lb 3/6/2006 United States
Primary
Secondary
Concomitant
Mental Status Changes Life Threatening 6/14/2004 49 Female 3/14/2006 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Required Intervention 12/28/2005 13 Female 79 lb 3/16/2006 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malignant Hypertension Life Threatening 9/20/2004 46 Female 3/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/20/2006 Spain
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 176 lb 4/5/2006 Physician Spain
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Tachycardia Required Intervention 3/23/2006 45 Male 4/6/2006 Physician Mexico
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 50 Male 176 lb 4/10/2006 Physician Spain
Primary
Concomitant
Ventricular Tachycardia Death 31 Male 165 lb 4/13/2006 Physician Australia
Primary
Concomitant
Procedural Complication Life Threatening 62 Female 154 lb 4/21/2006 Physician United States
Primary
Concomitant
Haemolysis Other Serious 3/23/2006 50 Male 149 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Genital Other Serious 5/1/2005 74 Male 165 lb 4/24/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 30 Male 161 lb 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/26/2006 Male 152 lb 4/9/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 22 Female 4/19/2006 Physician United States
Primary
Concomitant
Urinary Casts Other Serious 23 Male 4/21/2006 United States
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 5/3/2006 Spain
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 30 Male 161 lb 5/5/2006 Spain
Primary
Secondary
Concomitant
Rash Other Serious 4/13/2006 52 Male 190 lb 5/10/2006 Consumer United Kingdom
Primary
Concomitant
Neuromuscular Blockade Other Serious 11 Male 77 lb 5/15/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Rash Erythematous Life Threatening 1/31/2006 61 Male 5/16/2006 Consumer Australia
Primary
Secondary
Pulse Absent Other Serious 2/6/2005 63 Male 5/22/2006 Pharmacist United States
Primary
Concomitant
Urticaria Generalised Other Serious 23 Male 5/24/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 43 Male 216 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Penile Swelling Other Serious 74 Male 165 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Swelling Face Life Threatening 10/3/2004 18 Female 99 lb 5/31/2006 Consumer Australia
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Priapism Other Serious 17 Male 6/9/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Spinal Cord Disorder Disability 62 Male 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 2/25/2006 80 Female 141 lb 6/20/2006 Physician Japan
Primary
Concomitant
Rash Erythematous Life Threatening 1/31/2006 61 Male 7/18/2006 Consumer Australia
Primary
Secondary
Dyskinesia Required Intervention 58 Male 8/11/2006 Physician United States
Primary
Secondary
Sepsis Required Intervention 6/17/2006 63 Male 8/31/2006 Malaysia
Primary
Concomitant
Respiratory Arrest Death 13 Female 9/7/2006 Other Health Professional United States
Primary
Secondary
Procedural Complication Other Serious 6/29/2006 66 Male 198 lb 9/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death 13 Female 9/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Procedural Complication Other Serious Male 9/29/2006
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 9/29/2006
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Tumour Necrosis Hospitalization 3/23/2006 63 Male 152 lb 11/29/2006 Physician Germany
Primary
Concomitant
Intra-uterine Death Death 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 31 Female 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria 43 Female 1/10/2007 Canada
Primary
Concomitant
Surgery Other Serious 69 Female 1/23/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Rash Macular Life Threatening 10/31/2006 49 Female 1/4/2007 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 75 Male 1/26/2007
Primary
Secondary
Convulsion Other Serious 75 Male 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensory Disturbance Required Intervention 1/30/2007 39 Female 250 lb 2/8/2007 Other Health Professional United States
Primary
Concomitant
Tongue Oedema Hospitalization 70 Female 86 lb 2/12/2007 Other Health Professional Japan
Primary
Concomitant
Tachycardia Required Intervention 75 Male 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 9/21/2006 76 Female 134 lb 3/15/2007 United Kingdom
Primary
Secondary
Concomitant
Pregnancy Test Positive Hospitalization 2/24/2007 28 Female 3/8/2007 Czech Republic
Primary
Secondary
Concomitant
Twin Pregnancy Hospitalization 2/25/2007 28 Female 3/16/2007 Czech Republic
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 10/25/2006 67 Female 3/29/2007 Other Health Professional Australia
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/4/2006 56 Male 214 lb 1/19/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 31 Male 1/18/2007 Physician United States
Primary
Concomitant
Urticaria Life Threatening 5/26/2006 43 Female 4/3/2007 Canada
Primary
Concomitant
Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/13/2007 Physician Norway
Primary
Secondary
Concomitant
Vomiting Required Intervention 2/22/2007 54 Male 4/9/2007 United Kingdom
Primary
Concomitant
Urticaria Life Threatening 5/26/2006 44 Female 4/10/2007 Canada
Primary
Concomitant
Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/16/2006 43 Male 4/18/2007 Physician France
Primary
Secondary
Concomitant
Vomiting 2/22/2007 54 Male 4/10/2007 United Kingdom
Primary
Secondary
Concomitant
Procedural Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/11/2007 United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 12/11/2006 39 Female 139 lb 4/19/2007 Physician Germany
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2007 54 Male 249 lb 4/16/2007 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/16/2006 43 Male 4/25/2007 Physician France
Primary
Secondary
Concomitant
Muscle Rigidity Death 4/16/2007 14 Male 132 lb 4/27/2007 Physician Romania
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 60 Male 4/27/2007 Netherlands
Primary
Concomitant
Wound Secretion Hospitalization 10/25/2006 67 Female 4/30/2007 Other Health Professional Australia
Primary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/30/2007 Physician Norway
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vertigo Hospitalization 60 Male 4/28/2007 Consumer United Kingdom
Primary
Concomitant
Somnolence Hospitalization 65 Female 254 lb 4/28/2007 Consumer United Kingdom
Primary
Concomitant
Neuropathy Peripheral Life Threatening 12/7/2004 Male 5/4/2007 Physician Norway
Primary
Concomitant
Neuropathy Peripheral Life Threatening 10/13/2006 Male 5/4/2007 Other Health Professional Norway
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Life Threatening 3/16/2006 Male 5/4/2007 Physician Norway
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Post Procedural Complication Hospitalization 73 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 4/16/2007 14 Male 132 lb 5/11/2007 Physician Romania
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 30 Male 5/16/2007 United States
Primary
Secondary
Concomitant
Wheezing Disability 4/5/2007 74 Male 160 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Sinus Tachycardia Life Threatening 13 Male 93 lb 5/24/2007 Brazil
Primary
Concomitant
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/9/2007 Female 150 lb 6/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Supraventricular Tachycardia Required Intervention 40 Female 161 lb 5/29/2007 Physician United States
Primary
Concomitant
Rales Other Serious 4/29/2007 31 Male 165 lb 6/11/2007 Physician United Kingdom
Primary
Concomitant
Ventricular Dysfunction Death 36 Female 6/14/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Death 6/6/2007 65 Male 187 lb 6/15/2007 Pharmacist Canada
Primary
Concomitant
Postoperative Fever 9/14/2006 62 Male 244 lb 6/22/2007 Other Health Professional United States
Primary
Secondary
Sinus Tachycardia Life Threatening 63 Male 6/29/2007 Japan
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 79 Female 110 lb 7/11/2007 Physician United States
Primary
Concomitant
Interacting
Rash Macular 1/23/2007 Male 229 lb 7/12/2007 Other Health Professional Australia
Primary
Concomitant
Circulatory Collapse Life Threatening 40 Female 143 lb 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Lipase Increased Other Serious 8/29/2006 56 Female 7/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Erythema Other Serious 6/8/2007 41 Female 7/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Hyponatraemia Required Intervention 31 Female 190 lb 8/1/2007 Physician United States
Primary
Concomitant
Erythema Other Serious 6/8/2007 41 Female 8/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vein Disorder Required Intervention 22 Male 8/8/2007 Physician United States
Primary
Secondary
Concomitant

Drug Data