Midazolam Hcl combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatitis Fulminant Hospitalization 1/3/2006 28 Female 121 lb 1/31/2006 Consumer France
Primary
Secondary
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1 Female 2/6/2006
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Peritoneal Effusion Hospitalization 11/1/2005 46 Male 181 lb 2/20/2006 Other Health Professional France
Primary
Secondary
Tremor Hospitalization 2 Female 2/14/2006 Physician Italy
Primary
Concomitant
Peritoneal Effusion Hospitalization 11/1/2005 46 Male 2/22/2006
Primary
Secondary
Concomitant
Peritoneal Effusion Hospitalization 11/23/2005 46 Male 181 lb 2/22/2006 Consumer France
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Tremor Hospitalization 1 Female 3/3/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 11/19/2005 Female 44 lb 3/2/2006 United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/7/2006 Spain
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/20/2006 Spain
Primary
Concomitant
Respiratory Failure Life Threatening 6/3/2005 63 Male 218 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 1/18/1997 1 Male 20 lb 4/3/2006 Physician United States
Primary
Concomitant
Brain Oedema Life Threatening 2/24/2006 1 Male 13 lb 3/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 3/20/2006 55 Male 3/31/2006 India
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 176 lb 4/5/2006 Physician Spain
Primary
Concomitant
Thrombocytopenia Life Threatening 3/20/2006 55 Male 4/6/2006 Other Health Professional India
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 50 Male 176 lb 4/10/2006 Physician Spain
Primary
Concomitant
Ventricular Tachycardia Death 31 Male 165 lb 4/13/2006 Physician Australia
Primary
Concomitant
Haemolysis Other Serious 3/23/2006 50 Male 149 lb 4/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Somnolence Other Serious 44 Female 5/3/2006 Physician Brazil
Primary
Concomitant
Puncture Site Haemorrhage Other Serious 4/8/2006 23 Female 130 lb 4/24/2006 Physician United Kingdom
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 5/3/2006 Spain
Primary
Concomitant
Urticaria 5/4/2006 Female 168 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Urticaria 5/4/2006 Female 163 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/28/2006 51 Female 5/9/2006 Other Health Professional Argentina
Primary
Concomitant
Interacting
Neonatal Disorder Other Serious 5/12/2006 Physician United States
Primary
Secondary
Concomitant
Somatosensory Evoked Potentials Abnormal Other Serious 7 Female 97 lb 5/20/2006 Australia
Primary
Concomitant
Somnolence Hospitalization 4/5/2006 2 Male 5/23/2006 Pharmacist United States
Primary
Secondary
Somnolence Hospitalization 3/21/2006 43 Male 216 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Swelling Face Life Threatening 10/3/2004 18 Female 99 lb 5/31/2006 Consumer Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2005 41 Male 6/15/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2005 41 Male 6/22/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2005 41 Male 6/22/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 2/25/2006 80 Female 141 lb 6/20/2006 Physician Japan
Primary
Concomitant
Nerve Root Compression Other Serious 7 Female 97 lb 7/6/2006
Primary
Concomitant
Treatment Noncompliance Life Threatening 3/20/2006 55 Male 8/23/2006 India
Primary
Concomitant
Toxic Shock Syndrome Hospitalization 27 Male 8/22/2006
Primary
Secondary
Concomitant
Sepsis Required Intervention 6/17/2006 63 Male 8/31/2006 Malaysia
Primary
Concomitant
Procedural Complication Other Serious Male 9/29/2006
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 9/29/2006
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 11/9/2006 14 Male 90 lb 12/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Shock Syndrome Hospitalization 27 Male 12/7/2006 Physician Netherlands
Primary
Concomitant
Delirium Other Serious 11/27/2006 11 Female 1/30/2007 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/5/2007 Physician Australia
Primary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Post Procedural Complication Hospitalization 2/2/2007 80 Female 146 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/13/2007 Physician Australia
Primary
Concomitant
Vomiting Other Serious 59 Female 2/21/2007
Primary
Concomitant
Sepsis Life Threatening 1/14/2007 Male 353 lb 2/26/2007 Physician Australia
Primary
Concomitant
Haemorrhage Death 2/15/2007 Male 220 lb 2/27/2007 Physician Australia
Primary
Concomitant
Vomiting Other Serious 59 Female 2/22/2007 Switzerland
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 3/9/2007 Physician Australia
Primary
Concomitant
Haemorrhage Death 2/15/2007 Male 220 lb 3/12/2007 Physician Australia
Primary
Concomitant
Sepsis Neonatal Death 7/23/2006 0 Male 3/12/2007 Netherlands
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Renal Failure Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Cardiovascular Insufficiency Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Respiratory Failure Hospitalization 3/28/2007 Physician Italy
Primary
Concomitant
Sepsis Death 7/23/2006 0 Male 3/28/2007 Netherlands
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 4/11/2007 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 4/3/2007 59 Female 187 lb 4/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Superior Vena Caval Occlusion Life Threatening 3/1/2007 Male 7 lb 4/13/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/16/2006 43 Male 4/18/2007 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Cardiovascular Insufficiency Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 4/23/2007 Physician Australia
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Respiratory Failure Hospitalization 4/23/2007 Physician Italy
Primary
Concomitant
Hypertension Other Serious 4/2/2007 6 Male 44 lb 4/23/2007 Physician
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/16/2006 43 Male 4/25/2007 Physician France
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/1/2007 Physician Australia
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Patent Ductus Arteriosus Death 4/12/2007 0 Female 4/27/2007 Consumer Netherlands
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Sedation Other Serious 8/23/2005 41 Male 5/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/14/2007 Physician Australia
Primary
Concomitant
Superior Vena Caval Occlusion Life Threatening 3/1/2007 Male 7 lb 5/24/2007 Physician United States
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/29/2007 Physician Australia
Primary
Concomitant
Wound Infection Life Threatening 1/14/2007 Male 353 lb 5/29/2007 Physician Australia
Primary
Concomitant
Haemorrhage Death 2/15/2007 Male 220 lb 6/11/2007 Physician Australia
Primary
Concomitant
Rales Other Serious 4/29/2007 31 Male 165 lb 6/11/2007 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 4 Male 6/12/2007
Primary
Secondary
Coagulopathy Death 2/15/2007 Male 220 lb 7/16/2007 Physician Australia
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 4 Male 7/3/2007 United States
Primary
Secondary
Circulatory Collapse Life Threatening 40 Female 143 lb 7/11/2007 Consumer United Kingdom
Primary
Concomitant
Paradoxical Pain Hospitalization 12/7/2006 64 Male 7/16/2007
Primary
Secondary
Concomitant
Lipase Increased Other Serious 8/29/2006 56 Female 7/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Tremor Other Serious 8/11/2006 82 Male 8/10/2007 Physician United Kingdom
Primary
Concomitant
Hepatitis Death 1/1/2006 63 Male 123 lb 8/17/2007 Pharmacist Canada
Primary
Concomitant
Respiratory Rate Decreased Hospitalization 3/25/2007 6 Female 8/17/2007
Primary
Secondary
Concomitant
Hepatitis Death 1/1/2006 63 Male 123 lb 8/20/2007 Pharmacist Canada
Primary
Concomitant
Methaemoglobinaemia Hospitalization 57 Male 8/20/2007
Primary
Secondary
Concomitant
Splenomegaly Death 3/12/2007 32 Male 165 lb 8/31/2007 United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 6/4/1998 Female 9/24/2007 Germany
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/25/2007 Male 154 lb 10/3/2007 Physician United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 5/14/2007 18 Male 180 lb 10/24/2007 United States
Primary
Concomitant
Respiratory Depression Life Threatening 53 Female 128 lb 11/19/2007
Primary
Secondary
Concomitant
White Blood Cell Analysis Increased Other Serious 1/1/2000 71 Female 11/22/2007 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 3/12/2007 32 Male 165 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Effect Decreased Other Serious 58 Female 11/30/2007
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Heart Rate Abnormal Required Intervention 58 Female 11/27/2007 Consumer Australia
Primary
Concomitant
Extrapyramidal Disorder Hospitalization 82 Male 12/3/2007
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 82 Female 12/6/2007
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/23/2007 8 Male 57 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Overdose Death 9/1/2005 61 Male 1/17/2008
Primary
Secondary
Overdose Death 9/1/2005 Female 1/17/2008
Primary
Secondary
Overdose Death 9/1/2005 1/17/2008
Primary
Secondary
Overdose Death 9/1/2005 Female 1/17/2008
Primary
Secondary
Cerebrovascular Accident Other Serious 1/23/2008
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/1/2007 65 Male 1/22/2008 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Subdural Haemorrhage Other Serious 7/4/2007 2/14/2008 Physician Canada
Primary
Concomitant
Circulatory Collapse Hospitalization 1/16/2008 73 Male 2/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ultrasound Abdomen Abnormal Hospitalization 7/17/2007 72 Male 174 lb 2/4/2008 Physician Australia
Primary
Secondary
Concomitant
Syncope Hospitalization 1/16/2008 73 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 2/25/2008
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 7/17/2007 72 Male 174 lb 2/4/2008 Physician Australia
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/1/2004 33 Female 2/28/2008 Consumer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/13/2008 11 Female 44 lb 2/26/2008 Physician Ireland
Primary
Concomitant
Hypoperfusion Other Serious 3/3/2008
Primary
Concomitant
Apnoea Other Serious 3/3/2008
Primary
Concomitant
Serotonin Syndrome Hospitalization 58 Female 3/10/2008
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/13/2008 11 Female 44 lb 3/13/2008 Ireland
Primary
Concomitant
Hyperaesthesia Hospitalization 3/25/2008 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 40 Male 3/27/2008 Physician Colombia
Primary
Concomitant
Subdural Haemorrhage Other Serious 7/4/2007 3/28/2008 Physician Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 6/16/1986 66 Male 3/31/2008 Physician Norway
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 11 Male 3/29/2008 Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/28/2008 Male 4/1/2008 Physician Italy
Primary
Concomitant
Sudden Death Death 6/16/1986 66 Male 4/10/2008 Physician Norway
Primary
Secondary
Concomitant

Drug Data