Metronidazole combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 9/12/2005 73 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 12/14/2005 46 Female 110 lb 1/20/2006 United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/14/2005 46 Female 110 lb 4/20/2006 Physician United States
Primary
Concomitant
Hyperthermia Malignant Death 51 Female 220 lb 6/21/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 2/8/2006 36 Male 279 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/1/2007 50 Female 220 lb 6/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/1/2007 50 Female 7/6/2007 United Kingdom
Primary
Concomitant
Seroma Hospitalization 4/20/2006 Female 152 lb 9/6/2007 Physician Switzerland
Primary
Concomitant
Rash Erythematous Other Serious 8/15/2007 1 Female 26 lb 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Ventricular Fibrillation Life Threatening 11/20/2006 85 Female 11/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 73 Male 12/18/2007 Physician Switzerland
Primary
Secondary
Concomitant
Retinopathy Of Prematurity Disability 11/2/2007 0 Female 2 lb 12/19/2007 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2007 78 Male 141 lb 12/28/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious Male 1/15/2009 Physician Germany
Primary
Secondary
Hepatitis Acute Other Serious Male 1/12/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious Male 1/16/2009 Other Health Professional Germany
Primary
Secondary
Hepatitis Acute Other Serious Male 1/16/2009 Germany
Primary
Secondary
Vulvovaginal Dryness Other Serious 2/20/2003 36 Female 171 lb 4/15/2009 United States
Primary
Concomitant
Injury Other Serious 1/29/2007 59 Female 6/4/2009 Physician Korea, Republic Of
Primary
Concomitant
Weight Decreased Death 68 Male 6/5/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2009 Male 213 lb 7/8/2009 Physician United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Splenomegaly Other Serious 1/29/2007 59 Female 7/7/2009 Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Death 68 Male 7/14/2009 United States
Primary
Concomitant
Clostridium Difficile Colitis Life Threatening 4/7/2009 84 Female 7/22/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Weight Decreased Death 68 Male 7/17/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/21/2009 United States
Primary
Concomitant
Drug Interaction Hospitalization 5/4/2009 84 Female 139 lb 7/28/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Renal Failure Other Serious 7/1/1998 41 Female 233 lb 7/27/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 8/25/2009 United States
Primary
Concomitant
Myoclonus Other Serious 5/10/2009 60 Male 8/18/2009 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization 90 Female 9/2/2009 United States
Primary
Concomitant
Surgery Hospitalization 90 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Metastases To Peritoneum Life Threatening 6/4/2009 47 Male 9/4/2009 Physician Poland
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 1/29/2007 59 Female 8/31/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 9/16/2009 United States
Primary
Concomitant
Ballismus Hospitalization 59 Female 9/29/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Splenomegaly Hospitalization 1/29/2007 59 Female 9/24/2009 Physician Korea, Republic Of
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 223 lb 9/25/2009 United States
Primary
Concomitant
Mental Impairment Other Serious 59 Female 10/5/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 492 lb 10/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2006 83 Male 10/16/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2006 83 Male 10/22/2009 Consumer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Myoclonus Other Serious 60 Male 8/18/2009 Physician United Kingdom
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 90 Female 10/26/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 11/18/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2006 83 Male 11/17/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/25/2008 56 Male 11/20/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2008 56 Male 12/1/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2008 56 Male 12/11/2009 United States
Primary
Concomitant
Multiple Injuries Death 85 Female 1/15/2010 United States
Primary
Concomitant
Pain Hospitalization Female 1/15/2010 United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 4/7/2009 84 Female 139 lb 1/27/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Myoclonus Other Serious 60 Male 1/21/2010 Physician Chile
Primary
Concomitant
Urinary Tract Infection Hospitalization 68 Male 131 lb 1/20/2010 United States
Primary
Concomitant
Clostridium Difficile Colitis Life Threatening 4/7/2009 84 Female 2/5/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 60 Male 2/12/2010 Physician Chile
Primary
Concomitant
Toothache Other Serious 6/1/2005 Male 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/1/2009 15 Female 3/8/2010 Physician United States
Primary
Concomitant
Vasogenic Cerebral Oedema Other Serious 60 Male 3/4/2010 Chile
Primary
Concomitant
Toothache Other Serious 6/1/2005 Male 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/29/2009 Male 185 lb 3/15/2010 Physician Poland
Primary
Secondary
Concomitant
Trismus Other Serious 5/1/2007 Female 3/18/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 Female 3/26/2010 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 8/5/2009 Male 185 lb 3/31/2010 Physician Poland
Primary
Secondary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 4/16/2010 United States
Primary
Secondary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 4/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 73 Female 4/15/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 60 Male 4/22/2010 Physician Chile
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 4/28/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 42 Female 4/30/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 4/30/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 5/3/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Other Serious 1/29/2007 59 Female 4/23/2010 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/18/2010 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 5/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 5/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 12/9/2009 80 Female 117 lb 5/25/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Vomiting Hospitalization 10/19/2009 86 Male 5/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/28/2010 Physician Canada
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 10/28/2008 54 Male 216 lb 6/2/2010 Physician Canada
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 12/8/2009 80 Female 117 lb 6/3/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Clostridium Difficile Colitis Hospitalization 12/8/2009 80 Female 117 lb 6/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 12/8/2009 80 Female 6/7/2010 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 6/3/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Male 6/11/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 6/17/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/26/2010 65 Male 6/17/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 6/18/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 12/8/2009 80 Female 117 lb 6/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Clostridium Difficile Colitis Hospitalization 12/8/2009 80 Female 6/23/2010 Germany
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 2/24/2010 51 Male 146 lb 6/29/2010 Pharmacist United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 4/28/2010 64 Male 7/7/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/14/2009 67 Female 7/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Incontinence 8/12/2008 79 Female 130 lb 8/3/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/1998 41 Female 218 lb 8/6/2010 United States
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 6/1/2005 72 Male 8/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/13/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/27/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 86 Male 8/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/26/2010 65 Male 8/30/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vulvovaginal Dryness Other Serious 2/20/2003 36 Female 150 lb 9/3/2010 United States
Primary
Concomitant
Vomiting Hospitalization 86 Male 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/8/2008 71 Female 359 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 77 Male 131 lb 10/5/2010 United States
Primary
Concomitant
Pruritus Other Serious 1/1/2008 53 Male 245 lb 11/1/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Neonatal Other Serious 10/25/2010 Male 3 lb 12/1/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 42 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyloric Stenosis Other Serious 4/14/2009 67 Female 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 4/7/2009 84 Female 139 lb 2/15/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Clostridium Difficile Colitis Hospitalization 12/8/2009 80 Female 2/16/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pleural Effusion Death 4/14/2009 67 Female 2/14/2011 Physician Germany
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 12/17/2010 84 Female 216 lb 2/23/2011 Pharmacist United States
Primary
Secondary
Concomitant
Malignant Peritoneal Neoplasm Other Serious 4/14/2009 67 Female 2/23/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 6/4/2009 47 Male 2/23/2011 Physician Poland
Primary
Secondary
Concomitant
Ileus Death 6/4/2009 47 Male 3/3/2011 Other Health Professional Poland
Primary
Secondary
Concomitant

Drug Data