Metronidazole combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Unwanted Awareness During Anaesthesia Other Serious 49 Female 132 lb 1/5/2006 Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Skin Reaction Life Threatening 12/24/2005 78 Male 165 lb 1/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Failure Required Intervention 11/14/2005 74 Male 229 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Skin Reaction Life Threatening 12/24/2005 78 Male 165 lb 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 23 Female 205 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/17/2006 34 Female 110 lb 2/8/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 2/13/2006 76 Male 154 lb 3/13/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 3/1/2006 78 Male 4/12/2006
Primary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Reaction Life Threatening 12/24/2005 78 Male 165 lb 5/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 3/20/2006 78 Male 6/9/2006
Primary
Concomitant
Hepatitis Acute Life Threatening 5/8/2006 83 Female 143 lb 7/12/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Respiratory Depression Life Threatening 2/25/2005 44 Female 7/24/2006 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Life Threatening 5/8/2006 82 Female 143 lb 8/11/2006 Consumer Australia
Primary
Secondary
Concomitant
Pregnancy Other Serious 4/6/2004 39 Female 9/19/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 5 lb 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 11/29/2006 66 Female 12/22/2006 Physician United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 Female 5 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 3/1/2006 78 Male 3/16/2007 Other Health Professional Norway
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 31 Male 1/18/2007 Physician United States
Primary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/13/2007 Physician Norway
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/30/2007 Physician Norway
Primary
Secondary
Concomitant
Neuropathy Peripheral Life Threatening 12/7/2004 Male 5/4/2007 Physician Norway
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rales Other Serious 4/29/2007 31 Male 165 lb 6/11/2007 Physician United Kingdom
Primary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 1/30/2007 Male 225 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Required Intervention 6/1/2007 48 Female 6/8/2007 United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Hypotension Required Intervention 29 Female 3/12/2007 Physician United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Heart Rate Abnormal Required Intervention 58 Female 11/27/2007 Consumer Australia
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Death 9/11/2008 11 Female 90 lb 10/23/2008 Other Health Professional United States
Primary
Concomitant
Hypotension Life Threatening 46 Female 10/28/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Rash Erythematous Life Threatening 10/30/2008 74 Female 11/12/2008 Consumer Finland
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/28/2008 79 Male 11/20/2008 Physician United States
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 11/12/2008 63 Male 12/15/2008 Physician Switzerland
Primary
Concomitant
Interacting
Urosepsis Other Serious 1/1/2008 63 Male 12/17/2008 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 1/1/2004 20 Male 160 lb 4/14/2009 United States
Primary
Concomitant
Pancreatitis Required Intervention 2/1/2009 57 Female 163 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Blister Other Serious 5/17/2009 78 Female 154 lb 6/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blister Other Serious 5/17/2009 78 Female 154 lb 6/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blister Other Serious 5/17/2009 78 Female 154 lb 6/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Other Serious Female 9/23/2009 Consumer United Kingdom
Primary
Concomitant
Retching Required Intervention 6/12/2009 19 Male 159 lb 6/23/2009 Pharmacist United States
Primary
Concomitant
Muscle Spasms Other Serious Female 9/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious Female 9/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious Female 10/1/2009
Primary
Concomitant
Muscle Spasms Other Serious Female 10/8/2009 Consumer United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 10/22/2009 Female 158 lb 10/23/2009 Pharmacist United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 10/20/2009 40 Female 11/5/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 10/20/2009 Female 11/5/2009 Consumer Norway
Primary
Secondary
Concomitant
Transfusion Other Serious 1/1/2004 Male 11/5/2009 Physician United States
Primary
Concomitant
Transfusion Other Serious 1/1/2004 Male 11/16/2009 Other Health Professional United States
Primary
Concomitant
Muscle Spasms Hospitalization 8/6/2009 30 Female 11/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 30 Female
Primary
Secondary
Concomitant
Transfusion Other Serious 1/1/2004 Male 12/10/2009 Other Health Professional United States
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 14 Female 12/23/2009 Australia
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Transfusion Other Serious 1/1/2004 Male 2/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/31/2010 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 10/20/2009 40 Female 4/2/2010 Other Health Professional Norway
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 4/14/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Abnormal Other Serious 3/16/2010 0 Female 5/4/2010 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Hypotension Death Female 5/21/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/17/2010 54 Female 6/9/2010 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 6/15/2010 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 5/17/2010 54 Female 6/16/2010 Consumer France
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 52 Male 6/21/2010 Consumer Spain
Primary
Secondary
Concomitant
Coagulation Time Prolonged 7/24/2007 69 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 5/18/2010 54 Female 6/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 5/18/2010 54 Female 6/30/2010 Physician France
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 52 Male 7/7/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 52 Male 7/20/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Death 7/3/2010 19 Male 110 lb 7/30/2010 Physician Indonesia
Primary
Concomitant
Transfusion Other Serious 1/1/2004 77 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 5/19/2010 68 Female 7/30/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2008 31 Female 284 lb 8/17/2010 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Other Serious 45 Female 132 lb 8/19/2010 Other Health Professional China
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/1/2007 75 Male 9/2/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transfusion Other Serious 1/1/2004 77 Male 11/12/2010 Other Health Professional United States
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 9/12/2010 75 Male 11/19/2010 Other Health Professional Italy
Primary
Concomitant
Respiratory Depression Death 26 Female 130 lb 11/24/2010 Other Health Professional South Africa
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Vasospasm Other Serious 10/30/2010 62 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Upper Airway Obstruction Required Intervention 5/1/2007 48 Female 180 lb 12/14/2010 Consumer United States
Primary
Concomitant
Respiratory Depression Life Threatening 26 Female 130 lb 12/21/2010 Other Health Professional South Africa
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 7/9/2010 66 Male 1/25/2011 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 4/1/2008 31 Female 284 lb 2/3/2011 Lawyer United States
Primary
Concomitant
Dyspnoea Other Serious 8/1/2010 18 Female 163 lb 2/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Asthma Other Serious 4/1/2008 31 Female 284 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Hypovolaemic Shock Death 10/1/2007 75 Male 157 lb 3/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 9/12/2010 74 Male 4/8/2011 Other Health Professional Italy
Primary
Concomitant
Pulmonary Fibrosis Death 2/27/2011 60 Female 187 lb 5/10/2011 Physician Germany
Primary
Concomitant
Stress Cardiomyopathy Life Threatening 3/25/2011 48 Female 154 lb 5/12/2011 Other Health Professional Australia
Primary
Secondary
Angioedema Other Serious 18 Female 163 lb 7/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/1/2010 70 Male 165 lb 12/8/2011 Physician Germany
Primary
Concomitant
Asthenia Death 1/1/2010 70 Male 165 lb 2/28/2012 Physician Germany
Primary
Concomitant
Hypotension Hospitalization 4/13/2012 78 Male 172 lb 5/8/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 4/13/2012 78 Male 78 lb 5/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Resuscitation Hospitalization 4/13/2012 78 Male 176 lb 5/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/13/2012 78 Male 5/6/2012 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Life Threatening 4/23/2012 68 Male 5/10/2012 Physician Netherlands
Primary
Concomitant
Gastric Ulcer Hospitalization 4/23/2012 68 Male 5/16/2012 Physician Netherlands
Primary
Concomitant
Iliac Artery Occlusion Other Serious 4/23/2012 68 Male 5/16/2012 Physician Netherlands
Primary
Concomitant
Intestinal Ischaemia Other Serious 4/23/2012 68 Male 5/16/2012 Physician Netherlands
Primary
Concomitant
Renal Failure Other Serious 4/23/2012 68 Male 5/16/2012 Physician Netherlands
Primary
Concomitant
Intestinal Ischaemia Life Threatening 4/23/2012 68 Male 5/16/2012 Physician Netherlands
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 4/13/2012 78 Male 172 lb 5/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 4/23/2012 68 Male 5/17/2012 Physician Netherlands
Primary
Concomitant
Hypotension Hospitalization 4/13/2012 78 Male 176 lb 5/11/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 4/23/2012 68 Male 5/22/2012 Physician Netherlands
Primary
Concomitant
Ulcer Haemorrhage Death 4/23/2012 68 Male 5/22/2012 Physician Netherlands
Primary
Concomitant
Iliac Artery Occlusion Hospitalization 4/23/2012 68 Male 5/24/2012 Physician Netherlands
Primary
Concomitant
Methaemoglobinaemia Other Serious 48 Female 6/4/2012 Physician United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 56 Female 6/17/2012 United Kingdom
Primary
Concomitant
Anaphylactic Reaction Other Serious 56 Female 6/29/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 5/26/2012 35 Male 6/28/2012 Physician Italy
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 5/26/2012 35 Male 7/24/2012 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 38 Male 7/24/2012 Pharmacist United States
Primary
Secondary
Concomitant
Injury Hospitalization 5/5/2010 41 Female 173 lb 8/9/2012 Lawyer United States
Primary
Concomitant

Drug Data