Metronidazole combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Visual Disturbance Hospitalization 12/7/2005 51 Female 1/20/2006
Primary
Secondary
Concomitant
Renal Failure Death 6/1/2005 70 Female 190 lb 1/13/2006 United States
Primary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2005 72 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 3/21/2006 Physician Germany
Primary
Concomitant
Subileus Death 1/22/2006 58 Male 3/24/2006 Physician Poland
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 4/7/2006 Physician Germany
Primary
Concomitant
Pain In Extremity Hospitalization 10/15/2003 45 Male 4/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 1/1/2000 Female 220 lb 4/24/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/8/2006 Physician Germany
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 3/1/2006 51 Female 214 lb 5/8/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/7/2006 22 Female 195 lb 5/12/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/3/2006 65 Male 5/30/2006 Consumer France
Primary
Secondary
Concomitant
Insomnia Other Serious 5/2/2006 Male 441 lb 5/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 6/7/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2005 41 Male 6/15/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2005 41 Male 6/22/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/23/2005 41 Male 6/22/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7/4/2005 50 Male 6/19/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/19/2006 56 Male 161 lb 7/31/2006 Pharmacist United States
Primary
Concomitant
Blood Pressure Decreased Death 6/14/2006 Female 249 lb 8/21/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Giardiasis Hospitalization 38 Male 9/5/2006 Physician United States
Primary
Secondary
Concomitant
Interacting
Neonatal Disorder Disability 8/29/2006 0 Male 9/1/2006 United Kingdom
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/8/2006 United States
Primary
Concomitant
Pregnancy Other Serious 4/6/2004 39 Female 9/19/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Disability 8/29/2006 0 Male 10/4/2006 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Required Intervention 8/31/2006 65 Male 189 lb 9/27/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Neonatal Disability 8/29/2006 1 Male 10/9/2006 United Kingdom
Primary
Concomitant
Subileus Hospitalization 1/22/2006 58 Male 137 lb 10/23/2006 Physician Poland
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Patent Ductus Arteriosus Other Serious 10/24/2006 0 Male 11/1/2006 Spain
Primary
Concomitant
Toxic Shock Syndrome Hospitalization 1/1/2004 27 Male 10/24/2006 Physician Netherlands
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 5 lb 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 Female 5 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/13/2006 43 1/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Infusion Related Reaction 11/3/2006 Male 184 lb 1/22/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/13/2006 43 1/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Patent Ductus Arteriosus Other Serious 10/24/2006 0 Male 1/25/2007 Physician Spain
Primary
Concomitant
Paraesthesia Other Serious 9/1/2006 76 Female 134 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 10/23/2006 70 Male 3/20/2007 Consumer United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 10/9/2006 70 Male 3/22/2007 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 10/1/2006 70 Male 4/4/2007 Consumer United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
Subileus Hospitalization 10/1/2006 70 Male 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Other Serious 2/15/2007 Female 4/17/2007 Physician Germany
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 4/2/2007 6 Male 44 lb 4/23/2007 Physician
Primary
Concomitant
Hepatitis Other Serious 2/15/2007 64 Female 238 lb 4/24/2007 Physician Germany
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Sedation Other Serious 8/23/2005 41 Male 5/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Life Threatening 19 Male 5/7/2007 Physician Kuwait
Primary
Concomitant
Rales Other Serious 4/29/2007 31 Male 165 lb 6/11/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/13/2007 66 Male 143 lb 6/26/2007 Physician New Zealand
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/13/2007 66 Male 143 lb 7/12/2007 Physician New Zealand
Primary
Secondary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2004 7 lb 8/6/2007 Physician Switzerland
Primary
Secondary
Concomitant
Premature Baby Other Serious 1/1/2004 Female 154 lb 8/6/2007 Physician Switzerland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2003 60 Male 428 lb 8/9/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 8/11/2006 82 Male 8/10/2007 Physician United Kingdom
Primary
Concomitant
Hypotension Other Serious 6/6/2007 90 Female 117 lb 8/16/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/15/2007 42 Female 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Gallbladder Perforation Hospitalization 8/16/2007 Male 8/31/2007 Consumer Denmark
Primary
Secondary
Concomitant
Suture Related Complication Other Serious 10/24/2006 0 Male 2 lb 8/28/2007 Physician Spain
Primary
Concomitant
Gallbladder Perforation Hospitalization 8/16/2007 Male 9/19/2007 Consumer Denmark
Primary
Secondary
Concomitant
Multi-organ Failure Death 6/4/1998 Female 9/24/2007 Germany
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 30 Female 159 lb 10/18/2007
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 10/18/2007
Primary
Secondary
Somnolence 30 Female 159 lb 11/9/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/11/2007 Male 269 lb 11/14/2007 United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Hospitalization 1/1/2007 Male 218 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence 30 Female 159 lb 11/19/2007 United Kingdom
Primary
Secondary
Concomitant
Premature Baby Female 11/19/2007 United Kingdom
Primary
Secondary
Concomitant
Lip Swelling Required Intervention 10/4/2007 78 Female 161 lb 10/11/2007 Pharmacist United States
Primary
Concomitant
Hyponatraemia Other Serious 8/11/2007 Male 269 lb 11/26/2007 United States
Primary
Concomitant
Pustular Psoriasis Other Serious 30 Female 159 lb 11/29/2007 United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 10/15/2007 76 Male 183 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Pustular Psoriasis Hospitalization 30 Female 159 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Hospitalization Female 12/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Heart Rate Abnormal Required Intervention 58 Female 11/27/2007 Consumer Australia
Primary
Concomitant
Extrapyramidal Disorder Hospitalization 82 Male 12/3/2007
Primary
Secondary
Concomitant
Renal Failure Life Threatening Male 148 lb 12/5/2007 Poland
Primary
Concomitant
Tremor Hospitalization 12/4/2007 53 Female 1/3/2008 Consumer United Kingdom
Primary
Concomitant
Premature Baby Other Serious Female 1/14/2008 United Kingdom
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 30 Female 159 lb 1/14/2008 United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 12/15/2007 45 Male 1/15/2008 United Kingdom
Primary
Concomitant
Tremor Hospitalization 12/4/2007 53 Female 1/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Life Threatening 1/16/2008 Male 192 lb 1/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Life Threatening 1/16/2008 Male 192 lb 2/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 30 Female 159 lb 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 3/20/2008 62 Male 154 lb 8/13/2008 Pharmacist United States
Primary
Concomitant
Premature Baby Other Serious Female 2 lb 8/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Premature Baby Other Serious Female 2 lb 8/19/2008 Physician United Kingdom
Primary
Secondary
Pustular Psoriasis Other Serious 30 Female 159 lb 8/19/2008 Physician United Kingdom
Primary
Secondary
Ileus Paralytic Death 8/7/2008 Female 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 2 lb 8/29/2008 Physician United Kingdom
Primary
Secondary
Pustular Psoriasis Other Serious 30 Female 159 lb 8/29/2008 Physician United Kingdom
Primary
Secondary
Pustular Psoriasis Other Serious 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 7/18/2008 Male 88 lb 9/10/2008 Belgium
Primary
Concomitant
Somnolence Other Serious 30 Female 159 lb 9/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Hesitation 1/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Other Serious 9/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 30 Female 159 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Pustular Psoriasis Other Serious 30 Female 159 lb 9/16/2008 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pustular Psoriasis Other Serious 30 Female 159 lb 9/18/2008 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2006 Female 134 lb 9/19/2008 Physician United States
Primary
Concomitant
Premature Baby Other Serious Female 2 lb 9/26/2008 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 30 Female 159 lb 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Blood Potassium Increased Life Threatening 6/24/2008 Male 167 lb 7/2/2008 United States
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 11/26/2008 Physician United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 9/4/2008 35 Male 191 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/5/2009 Physician Chile
Primary
Secondary
Concomitant
Respiratory Distress Other Serious Male 1/13/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/20/2009 Physician Chile
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 64 Female 150 lb 1/21/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/22/2009 Physician Chile
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 3/24/2009 Physician Chile
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 4/7/2009 Physician Chile
Primary
Secondary
Concomitant

Drug Data