Metoprolol combined with Zolpidem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure 7/24/2004 54 Male 1/24/2006 Pharmacist United States
Primary
Concomitant
Polyomavirus-associated Nephropathy Hospitalization 3/27/2007 Male 184 lb 12/21/2007 Consumer Sweden
Primary
Secondary
Concomitant
Death Death 47 Female 1/14/2008 Physician United States
Primary
Secondary
Pneumonitis Hospitalization 5/19/2008 75 Male 164 lb 6/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 5/19/2008 75 Male 164 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 5/19/2008 75 Male 164 lb 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Optic Neuropathy Other Serious 3/1/2008 Male 240 lb 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 79 Male 6/25/2008 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 10/25/2007 Female 167 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/6/2007 Female 151 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2008 Male 4/8/2009 Consumer
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Social Problem Death 82 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 62 Male 8/4/2009 United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Surgery Hospitalization 64 Male 8/20/2009 United States
Primary
Concomitant
Tinnitus Death 80 Female 8/21/2009 Lawyer United States
Primary
Concomitant
Visual Impairment Hospitalization 62 Male 8/26/2009 United States
Primary
Concomitant
Tremor Required Intervention 7/21/2009 65 7/22/2009 United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 62 Male 9/23/2009 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious Female 10/2/2009 Other Health Professional United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Road Traffic Accident Life Threatening 10/1/2009 Male 10/4/2009 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Required Intervention 4/1/2009 Male 161 lb 8/24/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 10/10/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 79 Male 10/10/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 64 Male 10/18/2009 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/28/2009 Female 10/29/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vision Blurred Other Serious 59 Female 10/26/2009 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/19/2009 Male 160 lb 10/30/2009 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 9/4/2009 64 Male 11/2/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2009 48 Female 154 lb 10/22/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/26/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 64 Male 201 lb 10/26/2009 United States
Primary
Concomitant
Panic Attack Other Serious 62 Male 229 lb 10/26/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Female 11/2/2009 United States
Primary
Concomitant
Unemployment Other Serious 62 Male 229 lb 11/4/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 79 Male 11/9/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 11/9/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious Female 11/13/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 79 Male 11/18/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2006 75 Male 170 lb 11/30/2009 Physician Germany
Primary
Secondary
Concomitant
Muscle Atrophy Hospitalization 78 Male 12/1/2009 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Female 12/8/2009 United States
Primary
Concomitant
Wound Dehiscence Other Serious 9/4/2009 64 Male 1/12/2010 Other Health Professional United States
Primary
Concomitant
Skin Burning Sensation 1/1/2009 Female 165 lb 1/14/2010 Consumer United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2009 Female 147 lb 1/15/2010 United States
Primary
Concomitant
Surgery Hospitalization 66 Male 1/12/2010 Lawyer United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Rash Other Serious 2/1/2008 84 Female 1/27/2010 Lawyer United States
Primary
Concomitant
Somnambulism Other Serious 51 Female 1/29/2010
Primary
Secondary
Liver Injury Hospitalization 1/18/2010 88 Female 2/19/2010 Physician Switzerland
Primary
Secondary
Concomitant
Hypotension Death 10/1/2009 66 Male 152 lb 2/24/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2009 Female 3/24/2010 Physician United States
Primary
Concomitant
Palpitations Hospitalization 12/4/2009 57 Female 180 lb 4/2/2010 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 40 Male 4/19/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 4/19/2010 65 Male 200 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/28/2010 Other Health Professional United States
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 6/6/2008 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 5/4/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2010 68 Male 280 lb 5/5/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Female 176 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 70 Male 6/16/2010 Physician United States
Primary
Concomitant
Medication Residue 10/10/2007 77 Female 6/28/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 6/22/2010 78 Female 7/23/2010 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 3/17/2009 71 Male 194 lb 7/31/2010 Physician Sweden
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/27/2010 70 Male 231 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 7/3/2010 65 Male 110 lb 8/7/2010 Pharmacist United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 7/27/2010 70 Male 231 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/27/2010 70 Male 231 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Discomfort 9/1/2009 65 Female 178 lb 8/27/2010 United States
Primary
Concomitant
Flushing Female 107 lb 8/29/2010 Consumer United States
Primary
Concomitant
Medication Residue Female 9/17/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/1/2009 57 Male 9/17/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased 84 Male 154 lb 10/13/2010 United States
Primary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 10/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Other Serious 5/18/2009 63 Female 110 lb 10/21/2010 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 34 Female 10/28/2010 Other Health Professional United States
Primary
Secondary
Throat Irritation 80 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue 60 Female 10/13/2010 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 11/17/2007 75 Male 165 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 11/11/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 2/1/2010 89 Female 11/16/2010 Consumer United States
Primary
Concomitant
Tonsillitis Other Serious 1/1/2007 49 Male 11/23/2010 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/17/2010 68 Male 170 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 8/29/2010 64 Female 175 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Mood Swings 11/23/2010 53 Male 12/9/2010 Consumer
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Nausea Hospitalization 5/10/2010 85 Female 154 lb 5/31/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Erythema Other Serious 7/1/2010 52 Female 137 lb 1/6/2011 Consumer United States
Primary
Concomitant
Product Quality Issue 58 Male 1/7/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2007 49 Male 1/19/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Completed Suicide Death 38 Female 1/21/2011 Physician United States
Primary
Secondary
Completed Suicide Death 45 Female 1/21/2011 Physician United States
Primary
Secondary
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 1/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypoaesthesia 69 Female 1/29/2011 United States
Primary
Concomitant
Mouth Ulceration Other Serious 6/1/2009 50 Female 158 lb 1/29/2011 Consumer United States
Primary
Concomitant
Hyperthyroidism Male 325 lb 2/3/2011 Consumer United States
Primary
Concomitant
Weight Increased 3/1/2010 76 162 lb 2/3/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Death 1/1/2009 52 Male 1/17/2011 Other Health Professional United States
Primary
Secondary
Poisoning Death 1/1/2009 38 Female 1/25/2011 Physician United States
Primary
Secondary
Drug Ineffective Other Serious 1/4/2009 2/18/2011 Physician United States
Primary
Secondary
Concomitant
Nausea 12/15/2010 84 Male 2/18/2011 Consumer United States
Primary
Concomitant
Generalised Oedema Hospitalization 5/9/1997 37 Female 193 lb 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 47 Female 2/22/2011 Physician United States
Primary
Concomitant
Nerve Injury Other Serious 1/27/2011 58 Female 2/25/2011 Consumer United States
Primary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 3/1/2011 United States
Primary
Secondary
Concomitant
Aortic Aneurysm Other Serious 1/1/2004 69 Male 142 lb 3/7/2011 Physician United States
Primary
Secondary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Mouth Hospitalization 7/1/2010 52 Female 137 lb 3/25/2011 Consumer United States
Primary
Concomitant
Death Death 3/17/2011 86 Female 3/29/2011 United States
Primary
Concomitant
Dyspnoea Other Serious 2/1/2010 89 Female 3/29/2011 Consumer United States
Primary
Concomitant
Nerve Injury Other Serious 1/27/2011 58 Female 276 lb 3/31/2011 Consumer United States
Primary
Concomitant
Small Cell Lung Cancer Metastatic Hospitalization 2/28/2011 63 Male 230 lb 3/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Back Pain Other Serious 5/9/1997 37 Female 193 lb 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 2/15/2007 66 Male 174 lb 4/6/2011 Physician United States
Primary
Concomitant
Dyspnoea Life Threatening 11/17/2010 68 Male 170 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Eczema 1/1/2011 64 Female 207 lb 2/7/2011 Consumer United States
Primary
Concomitant
Odynophagia 1/1/2011 89 Female 4/25/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 69 Male 142 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 6/27/2001 4/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/9/1997 37 Female 193 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Anaemia Hospitalization 4/14/2009 72 Male 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Lymphocele Other Serious 9/10/2003 47 Male 5/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 3/7/2011 84 Female 7/19/2011 Physician Germany
Primary
Secondary
Concomitant
Os Trigonum Syndrome Other Serious 5/9/1997 37 Female 193 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Other Serious 2/1/2010 89 Female 8/23/2011 Consumer United States
Primary
Concomitant
Amnesia Hospitalization 10/14/2003 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/14/2003 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/12/2010 77 Female 114 lb 9/8/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 8/22/2011 81 Female 9/23/2011 Physician France
Primary
Secondary
Concomitant
Blood Triglycerides Increased Other Serious 8/1/2011 39 Female 240 lb 11/1/2011 Consumer United States
Primary
Concomitant
Seborrhoeic Keratosis Hospitalization Male 11/7/2011 Lawyer United States
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Sepsis Death 9/13/2011 77 Male 12/1/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2010 87 Female 12/26/2011 Physician United States
Primary
Secondary
Dermatitis Allergic Hospitalization 12/1/2011 58 Male 2/1/2012 Other Health Professional France
Primary
Secondary
Hypertonia Hospitalization 89 Female 2/6/2012 Physician Switzerland
Primary
Secondary
Serotonin Syndrome Death 1/1/2011 75 Female 226 lb 3/22/2012 Pharmacist United States
Primary
Secondary
Concomitant
Interacting
Serotonin Syndrome Death 1/1/2011 75 Female 226 lb 3/27/2012 Pharmacist United States
Primary
Concomitant
Interacting

Drug Data