Metoprolol combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/4/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/12/2006 Netherlands
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 11/11/2005 39 Male 335 lb 1/17/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/1/2005 76 Male 180 lb 2/6/2006 United States
Primary
Concomitant
Hypovolaemia Hospitalization 11/2/2005 58 Male Pharmacist United States
Primary
Secondary
Concomitant
Polyuria Hospitalization 11/11/2005 58 Male Pharmacist United States
Primary
Secondary
Concomitant
Palpable Purpura Hospitalization 1/25/2006 66 Male 161 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Initial Insomnia 71 Male 150 lb 1/5/2006 Consumer United States
Primary
Concomitant
Hyperhidrosis Life Threatening 48 Male 2/23/2006 United States
Primary
Secondary
Concomitant
Throat Tightness Life Threatening 9/18/2005 60 Female 183 lb 11/21/2005 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/6/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/26/2005 84 Male 245 lb 3/3/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Stress Hospitalization 12/12/2005 39 Female 170 lb 1/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2006 76 Male 194 lb 3/27/2006 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Life Threatening 10/28/2004 87 Male 87 lb 3/29/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/15/2003 66 Male 4/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Depression Hospitalization 11/20/2001 82 Male 134 lb 4/20/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 8/1/2001 75 Female 143 lb 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Confusional State Other Serious 5/27/2005 75 Female 4/27/2006 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2001 75 Female 143 lb 5/15/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 3/21/2006 81 Male 203 lb 4/28/2006 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 62 Male 223 lb 4/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 35 6/7/2006 Germany
Primary
Secondary
Tremor Hospitalization 88 Female 175 lb 6/7/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 5/8/2006 83 Female 135 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/17/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 7/2/2006 59 Male 165 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 4/1/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/20/2006 43 Male 7/25/2006 Physician Belarus
Primary
Concomitant
Rash Pruritic 65 Female 247 lb 8/1/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/7/2006 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/26/2006 66 Male 138 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 4/19/2003 69 Female 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/18/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 3/2/2006 74 Female 173 lb 9/14/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 151 lb 9/26/2006 Physician United States
Primary
Concomitant
Sinusitis Other Serious 72 Male 9/27/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Laboratory Test Abnormal Hospitalization 10/13/2006 83 Male 244 lb 10/17/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Nodal Arrhythmia Death 7/26/2006 86 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 68 Female 110 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/10/2005 75 Female 161 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 9/16/2006 79 Female 167 lb 11/8/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/1/2006 Male 158 lb 1/26/2007 Physician United States
Primary
Concomitant
Muscular Weakness Hospitalization 11/30/2006 73 Female 4/6/2007 Physician Canada
Primary
Concomitant
Drug Ineffective 1/1/1999 Male 9/24/2007 Consumer United States
Primary
Concomitant
Prostate Infection 1/1/2007 Male 9/24/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/27/2003 Female 228 lb 9/26/2007 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 46 Female 10/1/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 65 Female 10/1/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 23 Female 10/1/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 60 Male 10/1/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/7/2007 74 Female 10/2/2007 Denmark
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 9/6/2007 74 Male 176 lb 10/15/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 63 Male 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Required Intervention 8/23/2007 43 Female 104 lb 10/4/2007 United States
Primary
Concomitant
Somnolence 1/1/2006 75 Female 130 lb 10/5/2007 Consumer United States
Primary
Concomitant
Nausea 8/23/2007 65 Male 203 lb 10/5/2007 Consumer United States
Primary
Concomitant
Accidental Overdose 80 Male 10/24/2007 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 46 Female 10/23/2007 Physician United States
Primary
Concomitant
Prostate Infection 1/1/2007 Male 10/30/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2007 Female 133 lb 11/2/2007 Consumer United States
Primary
Concomitant
Infection Hospitalization 73 Female 11/9/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 81 Male 11/19/2007 Other Health Professional Canada
Primary
Secondary
Gastrointestinal Haemorrhage Required Intervention 10/8/2007 50 Female 11/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
Lethargy Required Intervention 10/24/2007 93 Male 179 lb 10/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 6/1/2007 78 Female 11/29/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Drug Ineffective 9/1/2007 Female 200 lb 12/14/2007 Consumer United States
Primary
Concomitant
Skin Discolouration 7/9/2007 66 Female 138 lb 12/17/2007 Physician United States
Primary
Concomitant
Nausea Hospitalization 10/1/2007 Female 12/7/2007 Consumer United States
Primary
Concomitant
Migraine Other Serious 1/1/2007 Male 220 lb 12/21/2007 Consumer United States
Primary
Concomitant
Hypertension Other Serious 3/22/2005 86 Female 12/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/27/2007 81 Male 12/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Physical Assault Other Serious 1/1/2006 Male 167 lb 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 10/27/2007 73 Female 1/3/2008 Consumer Australia
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 12/20/2007 81 Female 12/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 11/14/2007 70 Female 146 lb 12/3/2007 Pharmacist United States
Primary
Concomitant
Asthma Hospitalization 6/11/2006 63 Female 238 lb 1/16/2008 Consumer France
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 8/28/2007 51 Female 207 lb 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 5/17/2007 75 Male 6/11/2008 Consumer United States
Primary
Concomitant
Vertigo Disability 65 Male 6/12/2008 Other Health Professional Canada
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 4/21/2008 60 Male 5/2/2008 Pharmacist United States
Primary
Concomitant
Urinary Incontinence Other Serious 4/1/2008 Female 181 lb 6/18/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2003 Male 320 lb 6/19/2008 Lawyer United States
Primary
Concomitant
Onychoclasis 4/30/2007 82 Female 200 lb 6/24/2008 Physician United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 82 Female 236 lb 6/25/2008 Consumer United States
Primary
Concomitant
Haemorrhage Intracranial Other Serious 3/15/2008 69 Male 170 lb 6/27/2008 Consumer United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Death 1/22/2008 Male 193 lb 7/1/2008 Other Health Professional United States
Primary
Concomitant
Drug Interaction Other Serious 52 Male 7/11/2008 United States
Primary
Concomitant
Interacting
Hypoacusis Other Serious 5/1/2008 Male 271 lb 7/11/2008 Physician United States
Primary
Concomitant
Peritonitis Life Threatening 6/6/2008 Male 7/17/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/1/2007 Male 280 lb 7/11/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 3/19/2007 Male 205 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 85 Male 181 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 7/27/2007 65 Male 201 lb 7/29/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Decreased 1/1/2007 80 Female 150 lb 7/29/2008 Consumer United States
Primary
Concomitant
Feeling Cold 66 Male 225 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/5/2008 Male 8/1/2008 Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2007 Male 187 lb 8/4/2008 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 8/12/2008 Female 8/12/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 78 Female 187 lb 8/15/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/20/2006 Female 159 lb 8/22/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 Male 260 lb 8/22/2008 Consumer United States
Primary
Concomitant
Tinnitus 7/1/2008 69 Female 8/22/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 4/13/2008 67 Male 278 lb 9/4/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/20/2006 Female 159 lb 9/16/2008 Physician United States
Primary
Concomitant
Peritonitis Life Threatening 6/6/2008 Male 9/16/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2007 Male 280 lb 9/11/2008 Physician United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 6/1/2008 53 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 35 Female 11/20/2008 United States
Primary
Secondary
Vomiting Other Serious 1/1/2008 77 Male 210 lb 11/21/2008 Physician United States
Primary
Concomitant
Peripheral Coldness Other Serious 8/14/2008 Female 121 lb 11/21/2008 Pharmacist Canada
Primary
Concomitant
Cardiac Failure Other Serious 59 Male 11/21/2008 Italy
Primary
Concomitant
Fluid Retention Other Serious 7/1/2008 80 Male 190 lb 11/21/2008 Pharmacist United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2008 Male 321 lb 12/3/2008 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/28/2008 65 Male 200 lb 12/5/2008 Pharmacist United States
Primary
Secondary
Peripheral Coldness Other Serious 8/14/2008 Female 121 lb 12/10/2008 Pharmacist Canada
Primary
Concomitant
Thrombosis Hospitalization 35 Female 183 lb 12/11/2008 United States
Primary
Secondary
Haemorrhage Intracranial Hospitalization 3/15/2008 69 Male 170 lb 12/11/2008 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 10/21/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Palpitations 10/1/2008 43 Male 250 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Dry Mouth 4/1/2008 80 Male 12/19/2008 Consumer United States
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 5/1/2008 57 Female 185 lb 1/9/2009 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2007 Male 250 lb 1/8/2009 Physician United States
Primary
Concomitant
Haematuria Hospitalization 12/31/2008 58 Female 1/19/2009 Pharmacist United States
Primary
Secondary
Concomitant
Extrasystoles 8/1/2008 Male 1/30/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/13/2008 42 Male 2/11/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Female 2/18/2009 Physician United States
Primary
Concomitant
Epistaxis Other Serious 5/22/2008 58 Male 2/25/2009 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/9/2009 Male 2/26/2009 Physician Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 79 Female 3/6/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/7/2008 38 Female 139 lb 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Chest Pain 8/25/2008 78 Female 132 lb 3/9/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 12/4/2008 66 Female 3/10/2009 Sweden
Primary
Secondary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Renal Disorder Hospitalization 10/31/2008 79 Male 240 lb 2/26/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 65 Male 3/23/2009 Other Health Professional United States
Primary
Concomitant

Drug Data