Metoprolol combined with Tramadol

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haematocrit Decreased Hospitalization 12/28/2005 62 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 12/13/2005 70 Male Pharmacist United States
Primary
Concomitant
Respiratory Failure Death 12/16/2005 69 Male 143 lb 2/7/2006 Other Health Professional Poland
Primary
Concomitant
Respiratory Failure Death 12/16/2005 69 Male 143 lb 2/8/2006 Poland
Primary
Concomitant
Sudden Death Disability 11/3/2005 Male 4/14/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Erysipelas Hospitalization 5/1/2006 64 Female 10/24/2006 Consumer Sweden
Primary
Concomitant
Angioedema Hospitalization 12/10/2008 73 Female 170 lb 12/11/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 2/11/2008 Male 12/24/2008 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 4/1/2008 Male 3/11/2009 Other Health Professional United States
Primary
Secondary
Transaminases Increased Other Serious 6/9/2008 Female 116 lb 4/8/2009 Physician Philippines
Primary
Concomitant
Transaminases Increased Other Serious 6/9/2008 Female 116 lb 4/9/2009 Physician Philippines
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 3/1/2005 61 Male 246 lb 5/15/2009 United States
Primary
Concomitant
Angioedema Hospitalization 5/13/2009 Female 210 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2008 72 5/29/2009 Denmark
Primary
Secondary
Concomitant
Post-thoracotomy Pain Syndrome Other Serious 1/1/2008 Male 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Angioedema Hospitalization 5/13/2009 Female 210 lb 7/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 78 Male 145 lb 7/21/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/1/2009 48 Male 165 lb 7/29/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2008 72 7/30/2009 Denmark
Primary
Secondary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Papilloedema Hospitalization 7/9/2009 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 8/3/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Papilloedema Hospitalization 7/9/2009 Female 8/14/2009 Physician Switzerland
Primary
Secondary
Concomitant
Syncope Hospitalization 8/25/2008 Male 190 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 54 Male 200 lb 8/20/2009 Consumer United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 78 Male 145 lb 9/2/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Pneumonia Other Serious 9/11/2008 Male 10/2/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vomiting Other Serious 4/29/2006 Female 138 lb 10/8/2009 Lawyer United States
Primary
Concomitant
Presyncope Hospitalization 4/28/2009 Male 159 lb 10/6/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2007 Female 180 lb 12/30/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2009 Female 147 lb 1/15/2010 United States
Primary
Concomitant
Surgery Hospitalization 66 Male 1/12/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 1/1/2009 62 Male 1/22/2010 Other Health Professional United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 1/27/2010 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/3/2009 Female 1/27/2010 Other Health Professional United States
Primary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 178 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Intermittent Claudication Other Serious 7/10/2009 64 Male 164 lb 1/29/2010 Physician Netherlands
Primary
Concomitant
Vaginal Infection 9/1/2009 Female 204 lb 1/30/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2009 64 Male 201 lb 5/10/2010 Consumer United States
Primary
Concomitant
Osteoporosis Other Serious 3/1/2010 55 Female 201 lb 5/19/2010 Consumer United States
Primary
Concomitant
Osteoporosis Other Serious 3/1/2010 55 Female 201 lb 5/27/2010 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 2/3/2008 36 Female 216 lb 6/3/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Trismus Other Serious 1/1/2008 61 Male 130 lb 6/17/2010 Consumer United States
Primary
Concomitant
Wound Other Serious 6/1/2009 60 Female 6/17/2010 Other Health Professional United States
Primary
Concomitant
Ovarian Cancer Metastatic Life Threatening 5/16/2010 59 Female 195 lb 6/30/2010 Physician United States
Primary
Concomitant
Vomiting Life Threatening 9/25/2009 78 Female 6/30/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 4/1/2009 66 Male 7/7/2010 Physician United States
Primary
Concomitant
Product Adhesion Issue Death 6/28/2010 66 Male 143 lb 7/7/2010 Pharmacist Germany
Primary
Concomitant
Throat Irritation 5/8/2008 69 Female 7/7/2010 Other Health Professional United States
Primary
Concomitant
Drug Effect Decreased Life Threatening 6/11/2010 78 Female 168 lb 7/2/2010 Other Health Professional United States
Primary
Concomitant
Hypercalcaemia Hospitalization 12/1/2009 7/8/2010 Consumer United States
Primary
Concomitant
Nausea 12/1/2006 56 Male 195 lb 7/8/2010 Consumer United States
Primary
Concomitant
Interacting
Pyelonephritis Hospitalization 6/27/2010 63 Female 190 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 6/23/2010 57 Female 7/12/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/6/2009 79 Male 189 lb 6/29/2010 Physician United States
Primary
Concomitant
Neutrophil Count Increased Hospitalization 1/11/2010 51 Male 168 lb 7/16/2010 Physician Belgium
Primary
Secondary
Concomitant
Urosepsis Hospitalization 6/23/2010 57 Female 7/16/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Ovarian Cancer Metastatic Life Threatening 5/16/2010 59 Female 195 lb 7/19/2010 Physician United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Vein Disorder 12/1/2006 59 Male 165 lb 7/19/2010 Consumer United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/20/2010 Physician Belgium
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/1/2007 52 Male 234 lb 7/20/2010 Lawyer United States
Primary
Concomitant
Pyelonephritis Hospitalization 6/27/2010 63 Female 190 lb 7/22/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred 10/18/2007 69 Female 125 lb 8/3/2010 Physician United States
Primary
Concomitant
Swollen Tongue Hospitalization 7/3/2010 65 Male 110 lb 8/7/2010 Pharmacist United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2009 55 Female 192 lb 9/14/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 78 Male 145 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2005 45 Male 250 lb 9/17/2010 Consumer United States
Primary
Concomitant
Metrorrhagia 6/1/2009 65 Female 140 lb 9/17/2010 Other Health Professional United States
Primary
Concomitant
Muscle Atrophy 55 Female 172 lb 9/20/2010 United States
Primary
Concomitant
Oropharyngeal Pain 1/1/2009 81 Male 9/21/2010 Consumer
Primary
Concomitant
Pneumonia Hospitalization 3/23/2009 63 Female 9/21/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/6/2009 79 Male 189 lb 9/23/2010 Physician United States
Primary
Secondary
Concomitant
Pain 9/1/2010 85 Female 142 lb 10/11/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 71 Female 134 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/16/2010 59 Female 195 lb 10/22/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/26/2007 50 Female 265 lb 10/22/2010 Other Health Professional United States
Primary
Concomitant
Cataract Other Serious 61 Female 10/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 72 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Dry Mouth 82 Male 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Scratch Life Threatening 11/10/2010 71 Male 190 lb 11/12/2010 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 2/13/2008 66 Male 210 lb 11/5/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 49 Female 11/24/2010 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/17/2010 68 Male 170 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Hospitalization 11/22/2010 66 Female 201 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations 9/22/2010 47 Female 230 lb 12/13/2010 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 12/14/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 12/14/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 78 Male 145 lb 9/2/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2010 51 Female 278 lb 12/22/2010 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Other Serious 12/13/2010 81 Male 288 lb 12/22/2010 Consumer United States
Primary
Concomitant
Rash 12/11/2010 68 Female 1/7/2011 Consumer
Primary
Concomitant
Abdominal Discomfort 74 Female 1/10/2011 Consumer United States
Primary
Concomitant
Fatigue 8/1/2008 70 Female 1/13/2011 Consumer United States
Primary
Concomitant
Cough 10/1/2010 71 Male 1/14/2011 Consumer
Primary
Concomitant
Drug Ineffective Other Serious 12/30/2010 72 Female 118 lb 1/14/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 12/8/2009 72 Female 168 lb 1/20/2011 Consumer United States
Primary
Concomitant
Hydronephrosis Other Serious 11/1/2010 70 Female 132 lb 1/20/2011 Consumer United States
Primary
Concomitant
Death Death Female 1/25/2011 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 75 Female 1/26/2011 Consumer United States
Primary
Concomitant
Ileus Other Serious 9/23/2010 67 Female 249 lb 2/14/2011 Physician Germany
Primary
Concomitant
Hypotension 12/1/2010 68 Female 2/15/2011 Consumer United States
Primary
Concomitant
Abdominal Discomfort 11/2/2010 66 Female 2/16/2011 Consumer United States
Primary
Concomitant
Urinary Tract Disorder Death 11/1/2010 70 Female 132 lb 2/28/2011 Consumer United States
Primary
Concomitant
Vomiting 2/2/2011 85 Female 3/1/2011 Consumer United States
Primary
Concomitant
Terminal State Death 11/1/2010 70 Female 132 lb 3/1/2011 Consumer United States
Primary
Concomitant
Hallucination, Auditory Hospitalization 1/1/2008 47 Female 3/1/2011 Lawyer United States
Primary
Concomitant
Leukopenia Death 12/24/2010 Male 185 lb 2/28/2011 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/18/2010 88 Male 3/8/2011 Consumer Australia
Primary
Concomitant
Cough 10/1/2010 71 Male 3/10/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/3/2011 46 Female 200 lb 3/7/2011 Other Health Professional United States
Primary
Concomitant
Spinal Cord Disorder Other Serious 10/1/2010 47 Female 155 lb 3/17/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 36 Male 3/21/2011 Physician United States
Primary
Concomitant
Interacting
Pruritus Hospitalization Male 3/22/2011 Consumer United States
Primary
Concomitant
Abdominal Distension 12/1/2010 68 Female 3/25/2011 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 8/1/2008 70 Female 3/28/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 36 Male 4/1/2011 Physician United States
Primary
Concomitant
Interacting
Confusional State Other Serious 7/1/2010 80 Female 3/30/2011 Consumer United States
Primary
Concomitant
Meniscus Lesion Hospitalization 11/23/2008 69 Female 126 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Death 36 Male 4/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pneumonia Aspiration Death 10/1/2010 89 Female 154 lb 3/24/2011 Other Health Professional Germany
Primary
Concomitant
Dyspnoea Life Threatening 11/17/2010 68 Male 170 lb 3/24/2011 Other Health Professional United States
Primary
Concomitant
Convulsion Death 36 Male 4/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Dyspnoea Hospitalization 2/1/2011 85 Female 4/26/2011 Consumer United States
Primary
Concomitant
Wound Hospitalization 85 Female 4/26/2011 Consumer United States
Primary
Concomitant
Multiple Myeloma Death 1/28/2011 75 Male 4/26/2011 Pharmacist United States
Primary
Concomitant
Cellulitis Staphylococcal Hospitalization 6/1/2006 47 Female 153 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 12/8/2008 37 Female 216 lb 5/4/2011 Physician United States
Primary
Concomitant
Depression Other Serious 8/1/2007 58 Male 5/25/2011 Lawyer United States
Primary
Concomitant
Amnesia Other Serious 1/1/2008 Male 6/29/2011 Physician Netherlands
Primary
Concomitant
Nausea 6/21/2011 74 Female 125 lb 7/4/2011 Consumer United States
Primary
Concomitant
Nausea 6/21/2011 74 Female 125 lb 7/21/2011 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 9/22/2007 42 Female 7/28/2011 Lawyer United States
Primary
Concomitant
Poor Quality Drug Administered Hospitalization 80 Female 120 lb 1/31/2012 Consumer United States
Primary
Concomitant
Disease Progression Death Male 2/9/2012 Other Health Professional United States
Primary
Concomitant
Hallucination Other Serious 2/1/2011 46 Female 180 lb 2/19/2012 Consumer United States
Primary
Concomitant
Hypertension Other Serious Female 249 lb 2/28/2012 Consumer United States
Primary
Concomitant
Bronchitis Other Serious 11/1/2011 57 Female 249 lb 2/28/2012 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 2/25/2012 64 Male 211 lb 3/5/2012 Pharmacist United States
Primary
Concomitant