Metoprolol Tartrate combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Other Serious 10/14/2004 74 Male 176 lb 1/9/2006 Italy
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 6/28/2004 82 Female 231 lb 2/2/2006 Physician Poland
Primary
Concomitant
Renal Impairment Hospitalization 7/26/2005 69 Male 1/30/2006 Physician China
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1 Female 4/10/2006 Canada
Primary
Secondary
Rash Required Intervention 4/6/2006 83 Male 184 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 3/23/2006 69 Male 3/23/2006 Pharmacist United States
Primary
Secondary
Respiratory Failure Hospitalization 52 Male 4/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/13/2006 78 Male Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/4/2005 82 Female 123 lb 6/2/2006 Physician Australia
Primary
Concomitant
Rash Maculo-papular Other Serious 6/7/2006 66 Female 150 lb 6/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nausea 6/7/2006 58 Male 160 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 4/17/2006 70 Male 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/24/2006 55 Male Pharmacist United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/6/2006 52 Female 7/13/2006 Physician China
Primary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Thirst 63 Male 355 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious Female 9/6/2006 Canada
Primary
Concomitant
Pleural Effusion Hospitalization 6/6/2006 52 Female 9/5/2006 Physician China
Primary
Concomitant
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Bronchopneumonia Hospitalization 60 Male 9/14/2006 Other Health Professional Sweden
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 5/23/2006 73 Male 176 lb 10/3/2006 Poland
Primary
Secondary
Concomitant
Refusal Of Treatment By Relative Hospitalization 6/26/2006 52 Female 9/29/2006 China
Primary
Concomitant
Ill-defined Disorder Hospitalization 7/7/2006 82 Male 192 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/23/2006 58 Male Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2006 Male 11/2/2006 Physician
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2006 61 Male 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Linear Iga Disease Other Serious 73 Male 10/26/2006 Physician United States
Primary
Concomitant
Swelling Hospitalization 6/11/2006 Male 178 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious Male 250 lb 11/8/2006 United States
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 10/24/2006 76 Male 11/20/2006 Physician China
Primary
Concomitant
Pyrexia Other Serious 2/13/2005 71 Male 203 lb 12/11/2006 Physician Australia
Primary
Concomitant
Cardiac Failure Death 10/18/2005 65 Male 121 lb 10/6/2006 United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 9/28/2006 68 Female 115 lb 1/4/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 4/14/2006 80 Male 240 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 9/28/2006 61 Male 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 10/18/2006 80 Male 191 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Skin Discolouration Disability 55 Female 163 lb 2/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Peripheral Coldness 10/11/2006 88 Female 11/7/2006 Physician United States
Primary
Concomitant
Myalgia 11/8/2006 71 Female 116 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Other Serious 37 Male 205 lb 4/17/2007 Japan
Primary
Secondary
Concomitant
Constipation 87 Female 3/20/2007 United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2006 84 Female 129 lb 6/15/2007 Consumer United States
Primary
Secondary
Oedema Peripheral Other Serious 8/1/2006 84 Female 129 lb 6/28/2007 Consumer United States
Primary
Secondary
Thrombosis In Device Hospitalization 67 Male 7/3/2007 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/29/2007 64 Male 6/30/2007 Pharmacist United States
Primary
Secondary
Thrombosis In Device Hospitalization 67 Male 7/2/2007 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/1/2006 84 Female 129 lb 7/11/2007 Consumer United States
Primary
Secondary
Angioedema Other Serious 7/1/2007 Female 7/17/2007 Physician Canada
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 4/4/2007 Male 171 lb 7/20/2007 United States
Primary
Concomitant
Cardiac Operation Other Serious Male 9/8/2007 Consumer United States
Primary
Secondary
Cardiac Operation Other Serious Male 9/14/2007 Consumer United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/27/2007 80 Female 9/13/2007 Physician Canada
Primary
Secondary
Concomitant
Nausea 4/9/2007 73 Male 238 lb 9/20/2007 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 9/11/2007 Female 142 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/1/2006 84 Female 130 lb 10/9/2007 United States
Primary
Secondary
Drug Ineffective 5/16/2007 80 Female 10/3/2007 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2007 84 Female 10/11/2007 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 5/10/2007 67 Female 11/19/2007 Netherlands
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2007 76 Female 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Incoherent Other Serious 11/1/2007 Male 250 lb 12/31/2007 United States
Primary
Concomitant
Death Other Serious 9/1/2005 Male 1/7/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2007 78 Male 141 lb 12/28/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/26/2007 Male 1/21/2008 Other Health Professional France
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 80 Male 167 lb 1/26/2008 Other Health Professional United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 80 Male 167 lb 1/26/2008 Other Health Professional United States
Primary
Concomitant
Skin Cancer Other Serious 7/1/2007 73 Male 2/7/2008 United States
Primary
Concomitant
X-ray Abnormal Other Serious 4/2/2003 65 Female 148 lb 2/23/2008 Lawyer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/2/2003 65 Female 148 lb 2/22/2008 Lawyer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/2/2003 65 Female 148 lb 2/22/2008 Lawyer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/2/2003 65 Female 148 lb 2/22/2008 Lawyer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/2/2003 65 Female 148 lb 2/22/2008 Lawyer United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 4/2/2003 65 Female 148 lb 2/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Melaena Hospitalization 9/19/2007 61 Male 2/26/2008 Physician Switzerland
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/1/2007 82 Male 2/26/2008 Sweden
Primary
Concomitant
Prothrombin Level Decreased Other Serious 12/14/2007 Male 3/10/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Swelling 11/1/2007 69 Male 234 lb 3/11/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Quadriparesis Hospitalization 1/1/2008 47 Male 220 lb 3/5/2008 Consumer United States
Primary
Secondary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/4/2003 68 Female 3/4/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/4/2003 68 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Exfoliation 1/1/2008 52 Female 3/25/2008 Consumer United States
Primary
Concomitant
Rash Disability 12/27/2007 Male 296 lb 3/25/2008 Consumer United States
Primary
Concomitant
Renal Cancer Metastatic Hospitalization 5/17/2007 Female 227 lb 4/7/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death Female 227 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Unevaluable Event Required Intervention 1/1/2008 47 Male 220 lb 4/3/2008 United States
Primary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 195 lb 4/16/2008 Physician United States
Primary
Concomitant
Drug Ineffective 2/1/2008 80 Male 218 lb 4/30/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 195 lb 5/8/2008 Physician United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 4/16/2008 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Other Serious 8/1/2007 56 Male 271 lb 5/15/2008 Consumer United States
Primary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 12/28/2007 Male 215 lb 5/21/2008 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Death 5/11/2008 Female 185 lb 5/27/2008 Other Health Professional United States
Primary
Concomitant
Paralysis Required Intervention 1/1/2008 47 Male 220 lb 5/14/2008 United States
Primary
Concomitant
Fall Disability 5/7/2008 75 Female 142 lb 5/23/2008 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 Male 287 lb 6/13/2008 Physician United States
Primary
Concomitant
Interacting
Myocardial Infarction Death 1/1/2001 39 Male 7/2/2008 United States
Primary
Concomitant
Skin Exfoliation Other Serious 2/1/2008 83 Male 110 lb 7/18/2008 Consumer United States
Primary
Concomitant
Hypotension Other Serious 1/1/2006 54 Female 189 lb 7/24/2008 United States
Primary
Concomitant
Skin Lesion Other Serious 2/1/2008 Male 110 lb 7/28/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2008 56 Female 7/30/2008 Pharmacist Colombia
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/18/2008 80 Female 8/7/2008 Other Health Professional France
Primary
Concomitant
Renal Failure Hospitalization 75 Male 8/8/2008 Physician United States
Primary
Concomitant
Dry Mouth Disability 8/5/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 12/1/2007 Male 280 lb 8/19/2008 Physician United States
Primary
Concomitant
Oropharyngeal Pain 81 Male 8/15/2008 United States
Primary
Concomitant
Cerebral Haemorrhage Death 8/9/2008 Male 9/2/2008 Physician
Primary
Secondary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 9/5/2008 Germany
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 9/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 57 Male 9/8/2008 United States
Primary
Concomitant
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Vertigo 76 Female 179 lb 10/7/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 73 Female 166 lb 9/29/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/1999 51 Female 276 lb 10/15/2008 Consumer
Primary
Concomitant
Product Quality Issue 3/18/2008 66 Male 10/30/2008 Consumer United States
Primary
Concomitant
Death Death 10/24/2008 Male 220 lb 11/4/2008 Consumer United States
Primary
Concomitant
Blood Pressure Increased Other Serious 8/12/2008 76 Male 220 lb 11/7/2008 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 3/1/2008 Female 154 lb 11/7/2008 Germany
Primary
Concomitant
Hospitalisation Death 10/24/2008 Male 220 lb 11/10/2008 Physician United States
Primary
Concomitant
Paraesthesia Hospitalization 10/6/2008 38 Male 11/11/2008 Physician Germany
Primary
Concomitant
Status Epilepticus Life Threatening 9/1/2008 Female 11/16/2008 Physician Germany
Primary
Concomitant
Sleep Disorder 68 Male 11/11/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2007 69 Female 11/21/2008 Consumer Mexico
Primary
Concomitant
Vasculitis Life Threatening 11/7/2008 78 Male 218 lb 11/25/2008 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Male 11/26/2008 United States
Primary
Concomitant
Retinopathy Of Prematurity Hospitalization Female 3 lb 12/1/2008 Sweden
Primary
Secondary
Concomitant
Retinopathy Of Prematurity Other Serious Female 3 lb 12/1/2008 Sweden
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 8/1/2008 Female 130 lb 12/1/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2008 Female 11/25/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 8/5/2008 76 Male 282 lb 12/1/2008 Consumer United States
Primary
Concomitant
Urinary Incontinence Hospitalization 8/6/2008 77 Male 282 lb 12/3/2008 Consumer United States
Primary
Concomitant
Skin Ulcer Hospitalization 1/1/2008 47 Male 220 lb 12/4/2008 United States
Primary
Concomitant
Mouth Ulceration 12/1/2007 69 Female 157 lb 12/17/2008 Physician United States
Primary
Concomitant
Breast Tenderness 45 Male 12/17/2008 United States
Primary
Concomitant
Nervousness 85 Female 156 lb 12/17/2008 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 75 Female 12/18/2008 Other Health Professional Poland
Primary
Secondary

Drug Data