Metoprolol Tartrate combined with Senna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Haemorrhage Hospitalization 12/22/2005 Female United States
Primary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 2/5/2006 87 Female 137 lb 2/17/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 5/31/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 1/1/2006 Female 8/9/2006 Other Health Professional United States
Primary
Concomitant
Inadequate Analgesia Hospitalization 9/7/2006 Female 120 lb 10/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious 9/6/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 10/16/2006 Female 120 lb 10/30/2006 Other Health Professional United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 10/16/2006 42 Female 121 lb 11/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Hospitalization 1/16/2007 78 Male 194 lb 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 10/18/2006 80 Male 191 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Other Serious 12/16/2005 Male 246 lb 3/22/2007 Physician United States
Primary
Concomitant
Generalised Erythema Hospitalization 8/1/2006 86 Female 6/12/2007 Physician Japan
Primary
Concomitant
Pancreatic Carcinoma Metastatic Other Serious 12/16/2005 Male 246 lb 9/11/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 4/1/2006 64 Male 209 lb 10/8/2007 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2007 Female 133 lb 11/13/2007 Consumer United States
Primary
Concomitant
Deafness Disability 10/25/2007 70 Female 234 lb 12/27/2007 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 9/26/2004 Female 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Required Intervention 3/13/2007 70 Female 1/24/2008 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/1/2006 Female 132 lb 2/15/2008 Canada
Primary
Concomitant
Retching 1/2/2008 77 Female 157 lb 2/17/2008 United States
Primary
Concomitant
Retching 1/2/2008 77 Female 157 lb 2/27/2008 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 5/10/2007 82 Female 104 lb 3/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Renal Injury Hospitalization 21 Male 3/5/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/18/2008 Male 265 lb 3/11/2008 Canada
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 3/18/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 3/21/2008 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 3/26/2008 Physician United States
Primary
Secondary
Concomitant
Retinoic Acid Syndrome Required Intervention 1/4/2008 57 Female 206 lb 2/20/2008 United States
Primary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Other Serious 2/12/2008 65 Female 159 lb 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 2/21/2008 Male 154 lb 4/15/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Female 5/8/2008 Other Health Professional Australia
Primary
Concomitant
Splenic Rupture Other Serious 2/12/2008 65 Female 159 lb 5/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 11/28/2007 Female 300 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 6/10/2008 Female 236 lb 7/24/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Life Threatening Female 176 lb 7/25/2008 Other Health Professional Australia
Primary
Concomitant
Therapeutic Response Decreased Life Threatening Female 176 lb 7/29/2008 Other Health Professional Australia
Primary
Concomitant
Vomiting Other Serious 8/7/2008 77 Female 8/21/2008 United States
Primary
Concomitant
Tumour Flare Hospitalization 8/7/2008 Male 190 lb 8/28/2008 United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Depression Other Serious 6/10/2008 Female 236 lb 9/30/2008 United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/7/2008 Female 154 lb 10/14/2008 United States
Primary
Concomitant
Drug Ineffective 10/9/2008 Female 10/15/2008 Consumer
Primary
Concomitant
Tremor Other Serious 10/8/2008 60 Female 125 lb 11/1/2008 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 8/7/2008 Female 154 lb 11/11/2008 United States
Primary
Concomitant
Status Epilepticus Required Intervention 3/13/2007 70 Female 11/7/2008 Other Health Professional United States
Primary
Concomitant
Blood Potassium Increased Life Threatening 6/24/2008 Male 167 lb 7/2/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 10/9/2008 72 Female 10/20/2008 Pharmacist United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2008 Female 250 lb 12/19/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/11/2009 Female 1/20/2009 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Other Serious 12/16/2008 76 Female 251 lb 1/14/2009 Pharmacist United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 1/7/2009 60 Female 109 lb 1/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 Female 110 lb 2/20/2009 Physician United States
Primary
Concomitant
Road Traffic Accident Hospitalization 12/1/2005 58 Male 219 lb 3/13/2009 Consumer United States
Primary
Concomitant
Depression Other Serious 6/10/2008 Female 236 lb 3/13/2009 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Hospitalization 12/1/2005 58 Male 219 lb 3/16/2009 Consumer United States
Primary
Concomitant
Depression Other Serious 6/10/2008 Female 236 lb 3/19/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2008 Female 150 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/1/2009 62 Female 4/21/2009 United States
Primary
Secondary
Concomitant
Electrocardiogram T Wave Peaked Required Intervention 3/18/2009 59 Male 143 lb 3/19/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2009 Female 149 lb 7/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 9/1/2006 Female 7/13/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 Female 149 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 3/16/2007 Female 150 lb 9/11/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 11/5/2008 65 Female 11/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 9/13/2009 Male 111 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 4/11/2008 69 Male 2/1/2010 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Female 174 lb 2/4/2010 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/5/2010 Female 142 lb 2/7/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Mesenteric Vessel Other Serious 1/1/2009 Female 2/24/2010 Physician United States
Primary
Concomitant
Rash Papular 1/6/2010 65 Male 2/18/2010 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 1/19/2010 Male 2/25/2010 Other Health Professional United States
Primary
Concomitant
Rash Generalised Other Serious 2/1/2008 83 Female 137 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal 11/16/2009 Female 120 lb 12/15/2009 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 1/30/2010 Female 3/17/2010 Physician United States
Primary
Concomitant
Death Death 2/1/2009 Female 3/18/2010 United States
Primary
Concomitant
Vein Disorder Other Serious 8/1/2003 Female 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/30/2010 47 Female 4/8/2010 Physician United States
Primary
Concomitant
Dyspnoea Other Serious 10/1/2007 84 Female 4/13/2010 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 2/6/2008 76 Male 195 lb 4/23/2010 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/26/2010 79 Female 104 lb 5/4/2010 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Hospitalization 1/1/2009 77 Male 6/2/2010 Consumer Canada
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/1/2008 76 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 12/22/2009 46 Female 142 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/22/2010 63 Female 123 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 6/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 50 Male 209 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2008 76 Male 7/30/2010 Lawyer United States
Primary
Concomitant
Swelling Other Serious 6/15/2007 66 Male 278 lb 8/11/2010 Lawyer United States
Primary
Concomitant
Overdose Other Serious Male 8/11/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2010 71 Male 8/18/2010 Physician United States
Primary
Concomitant
Skin Discolouration 2/1/2010 61 Female 150 lb 8/31/2010 United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 9/1/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2007 73 Male 150 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 9/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Dilatation Hospitalization 7/27/2010 80 Female 92 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 4/11/2008 69 Male 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/27/2010 80 Female 92 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 9/30/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/15/2008 64 Female 181 lb 10/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/15/2007 66 Male 278 lb 10/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Periprosthetic Fracture Other Serious 12/9/2009 67 Female 11/19/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 11/22/2010 Lawyer United States
Primary
Concomitant
Rash Pruritic 7/30/2009 12/14/2010 Consumer United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 10/15/2010 54 Male 12/23/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 7/1/2008 12/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 2/6/2008 76 Male 195 lb 1/18/2011 Other Health Professional United States
Primary
Concomitant
Mass Other Serious Male 1/19/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 65 Female 2/9/2011 Lawyer United States
Primary
Concomitant
Clostridial Infection Death 10/15/2010 54 Male 250 lb 3/11/2011 Physician United States
Primary
Concomitant
Microangiopathy Hospitalization 89 Female 188 lb 3/7/2011 Lawyer United States
Primary
Concomitant
Meniscus Lesion Other Serious 1/1/2007 50 Male 3/29/2011 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 3/24/2011 85 Female 3/28/2011 Pharmacist United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/30/2009 83 Female 4/11/2011 United States
Primary
Concomitant
Lethargy Hospitalization 6/1/2000 68 Male 4/12/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/1/2011 85 Female 4/12/2011 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 3/23/2011 85 Male 4/13/2011 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Other Serious 11/30/2009 83 Female 4/15/2011 Consumer United States
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2008 63 Male 4/19/2011 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2008 63 Male 5/10/2011 Physician United States
Primary
Concomitant
Colonic Stenosis Death 7/27/2010 80 Female 92 lb 6/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dysarthria Other Serious 6/18/2009 86 Male 6/28/2011 Consumer United Kingdom
Primary
Concomitant
Memory Impairment Hospitalization 6/4/2011 62 Male 169 lb 7/1/2011 Physician United States
Primary
Concomitant
Dehydration Hospitalization 6/19/2011 51 Male 160 lb 7/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Life Threatening 9/23/2010 51 Male 181 lb 7/6/2011 Physician United States
Primary
Concomitant
Cerebral Haemorrhage Other Serious 11/30/2009 83 Female 7/7/2011 Consumer United States
Primary
Concomitant
Salivary Hypersecretion Hospitalization 7/1/2009 86 Male 7/12/2011 Consumer United Kingdom
Primary
Concomitant
Lumbar Spinal Stenosis Hospitalization 12/18/2006 67 Male 7/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Discomfort Death 7/19/2011 60 Male 7/21/2011 Consumer United States
Primary
Concomitant
Interacting
Vomiting Other Serious 1/19/2011 54 Male 7/25/2011 Consumer United States
Primary
Concomitant
Gout Hospitalization 4/27/2011 85 Female 8/9/2011 Physician Hong Kong
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/19/2011 51 Male 160 lb 8/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 7/9/2011 63 Female 102 lb 8/12/2011 Other Health Professional United States
Primary
Concomitant
Asthenia Hospitalization 5/1/2011 62 Female 214 lb 8/12/2011 Other Health Professional Canada
Primary
Concomitant
Gallbladder Disorder Other Serious 1/1/2011 71 Female 130 lb 8/12/2011 Other Health Professional United States
Primary
Concomitant
Colonic Polyp Other Serious 9/23/2003 66 Female 8/16/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 60 Female 150 lb 8/18/2011 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 7/1/2011 52 Female 174 lb 8/19/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data