Metoprolol Tartrate combined with Oxycodone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Wound Treatment Other Serious 5/1/2004 43 Male 258 lb 5/31/2006 Physician United States
Primary
Concomitant
Skin Discolouration Hospitalization 9/16/2006 52 Male 273 lb 9/19/2006 Other Health Professional United States
Primary
Concomitant
Headache Hospitalization 11/1/2005 Male 120 lb 1/18/2008 United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Neutropenia Hospitalization 12/28/2007 58 Female 119 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2004 45 1/30/2008 Physician Canada
Primary
Secondary
Drug Toxicity Death 1/1/2004 45 1/31/2008 Physician Canada
Primary
Secondary
Serotonin Syndrome Other Serious 11/25/2008 53 Male 158 lb 12/17/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Disability 9/29/2008 66 Female 1/22/2009 Consumer United States
Primary
Concomitant
Hypersensitivity 3/1/2008 61 Male 123 lb 2/18/2009 Lawyer United States
Primary
Concomitant
Gastrointestinal Perforation Life Threatening 12/15/2008 Male 176 lb 2/20/2009 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 2/21/2009 United States
Primary
Concomitant
Osteonecrosis Hospitalization 72 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Off Label Use Death 10/1/2006 Male 244 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2009 Female 149 lb 7/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2009 Female 149 lb 7/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 86 Female 7/20/2009 United States
Primary
Concomitant
Off Label Use Death 10/1/2006 Male 244 lb 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 7/25/2009 Female 8/4/2009 Other Health Professional United States
Primary
Concomitant
Off Label Use Death 10/1/2006 Male 244 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperhidrosis Male 230 lb 8/22/2009 Physician United States
Primary
Concomitant
Formication Male 8/22/2009 United States
Primary
Concomitant
Peptic Ulcer Haemorrhage Life Threatening 8/19/2009 61 Male 170 lb 8/31/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 6/20/2009 41 Male 141 lb 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Death 68 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Pyrexia 5/2/2009 55 Male 185 lb 8/1/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization Male 8/31/2009 Lawyer United States
Primary
Concomitant
Troponin Increased Hospitalization 72 Male 9/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Drug Toxicity Death 65 Male 203 lb 9/11/2009 Consumer United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Death 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 72 Male 9/9/2009 Lawyer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 9/15/2003 58 Male 132 lb 9/15/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Death 8/28/2009 Male 9/16/2009 Physician United States
Primary
Secondary
Concomitant
Odynophagia Hospitalization 10/26/2008 Male 154 lb 9/17/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 77 Female 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus 1/1/2004 45 Male 237 lb 9/23/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/1/2005 48 Female 166 lb 9/23/2009 United States
Primary
Concomitant
Respiratory Distress Hospitalization 51 Male 10/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 63 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 59 Female 140 lb 12/7/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 63 Male 12/9/2009 United States
Primary
Secondary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 12/11/2009 United States
Primary
Concomitant
Somnolence 10/6/2009 Female 12/22/2009 Consumer United States
Primary
Concomitant
Pain Disability 7/27/2009 Female 197 lb 12/23/2009 Physician United States
Primary
Concomitant
Sedation Other Serious Male 12/31/2009 Physician United States
Primary
Concomitant
Tinnitus Other Serious 9/1/2000 73 12/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious Male 1/5/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 Female 1/6/2010 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 1/18/2010 Male 229 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Wheezing Other Serious 3/1/2007 46 Male 231 lb 2/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 2/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/23/2009 Male 2/19/2010 United States
Primary
Concomitant
Visual Impairment Hospitalization 9/16/2009 Male 228 lb 2/25/2010 United States
Primary
Concomitant
Hyponatraemia Life Threatening 60 Female 156 lb 3/1/2010 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 1/15/2010 64 Male 226 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/20/2005 Male 3/19/2010 United States
Primary
Secondary
Concomitant
Thinking Abnormal Hospitalization 12/1/2009 Male 128 lb 3/23/2010 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/28/2008 Female 142 lb 3/30/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 2/1/2010 68 Female 214 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Tooth Fracture Other Serious 7/1/2004 62 Male 4/1/2010 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/9/2009 69 Male 293 lb 4/1/2010 Physician United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 3/17/2010 61 Male 176 lb 4/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Death 11/2/2007 39 Male 220 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 78 Male 4/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 4/5/2010 64 Male 200 lb 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged Hospitalization 12/15/2009 66 Female 4/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 9/9/2009 69 Male 293 lb 4/14/2010 Physician United States
Primary
Concomitant
Nausea Hospitalization 4/10/2010 50 Female 161 lb 4/12/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/8/2002 60 Female 120 lb 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Jaundice Other Serious 2/2/2010 72 Male 187 lb 4/16/2010 Physician United States
Primary
Concomitant
Sepsis Life Threatening 12/29/2007 73 Female 209 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 4/26/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 3/19/2010 71 Male 130 lb 4/26/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Calciphylaxis Hospitalization 1/1/2010 46 Female 4/28/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious Female 157 lb 4/28/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/15/2008 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/27/2010 38 Female 168 lb 3/4/2010 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Life Threatening 4/16/2010 54 Male 204 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Suicide Attempt Death 11/2/2007 39 Male 220 lb 5/17/2010 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 5/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/29/2007 73 Female 209 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 5/4/2010 58 Female 170 lb 5/14/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/8/2002 60 Female 120 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 5/1/2010 75 Male 192 lb 5/19/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/8/2002 60 Female 120 lb 5/21/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 6/21/2008 67 Female 146 lb 5/24/2010 Lawyer United States
Primary
Concomitant
Withdrawal Syndrome Life Threatening 4/1/2009 71 Female 198 lb 5/31/2010 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 3/14/2010 20 Female 120 lb 6/4/2010 United States
Primary
Concomitant
Venous Thrombosis Other Serious 1/1/2007 56 Male 235 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 2/1/2002 63 Male 140 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 5/6/2010 75 Male 192 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/28/2008 68 Female 142 lb 6/18/2010 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 1/1/2007 56 Male 235 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Death 11/2/2007 39 Male 220 lb 7/29/2010 Other Health Professional United States
Primary
Concomitant
Urosepsis Life Threatening 2/5/2010 70 Female 146 lb 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 6/21/2008 67 Female 146 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/1/2009 75 Male 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 7/1/2004 62 Male 8/9/2010 Pharmacist United States
Primary
Concomitant
Swelling Other Serious 6/15/2007 66 Male 278 lb 8/11/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2006 55 Male 8/13/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 46 Male 178 lb 8/16/2010 Lawyer United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 7/1/2004 62 Male 8/16/2010 United States
Primary
Concomitant
Optic Neuropathy Hospitalization 7/14/2010 66 Female 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 7/1/2009 75 Male 8/20/2010 Physician United States
Primary
Secondary
Concomitant
X-ray Other Serious 3/1/2004 74 Male 8/20/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/20/2005 66 Male 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1991 54 Male 188 lb 8/20/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/20/2005 66 Male 8/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 9/1/2010 United States
Primary
Concomitant
Oedema Peripheral Other Serious 5/22/2010 63 Female 9/3/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/30/2006 55 Male 9/7/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 6/16/2010 52 Male 227 lb 9/8/2010 Physician United States
Primary
Concomitant
Intestinal Dilatation Hospitalization 7/27/2010 80 Female 92 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 9/9/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 9/13/2010 Physician United States
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 7/20/2010 56 Female 183 lb 9/14/2010 United States
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 11/16/2009 47 Female 9/15/2010 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 3/12/2010 55 Male 9/16/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/18/2010 68 Female 181 lb 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 9/24/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 59 Male 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/9/2010 68 Female 181 lb 9/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 5/1/2009 66 Female 120 lb 9/29/2010 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/27/2010 80 Female 92 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1991 54 Male 188 lb 9/30/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Transplant Hospitalization 6/15/2007 47 Male 9/30/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/11/2010 59 Male 220 lb 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 1/1/2007 47 Male 10/4/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2010 83 Female 10/6/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 1/3/2008 48 Male 258 lb 10/6/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/7/2010 United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/7/2010 United States
Primary
Concomitant
Oedema Peripheral Other Serious 5/22/2010 63 Female 10/7/2010 United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 60 Male 10/8/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/31/2010 65 Male 10/7/2010 Consumer United States
Primary
Concomitant

Drug Data