Metoprolol Succinate combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Hospitalization 11/15/2005 71 Male 249 lb 1/17/2006 Physician Germany
Primary
Concomitant
Sarcoma Hospitalization 1/1/2003 Male 1/18/2006 United States
Primary
Concomitant
Tremor Hospitalization 12/7/2005 74 Male 213 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Infection Hospitalization 12/9/2005 74 Male 2/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tremor Other Serious 2/23/2002 46 Male 3/22/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 4/13/2006 Czech Republic
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Death 3/16/2006 81 Male 5/5/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/18/2006 80 Female 10/11/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Malaise 11/21/2006 83 Female 220 lb 11/22/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/27/2006 59 Male 223 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 10/10/2006 64 Male 12/12/2006 Physician Germany
Primary
Concomitant
Malaise 83 Female 220 lb 12/21/2006 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 11/30/2005 85 Female 1/3/2007 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 64 Male 12/22/2006 Physician Germany
Primary
Concomitant
Post Procedural Complication Hospitalization 1/1/2006 62 Female 200 lb 1/9/2007 Consumer United States
Primary
Concomitant
Haemorrhage Intracranial Other Serious 6/2/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/9/2004 176 lb 2/23/2007 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 74 Male 2/26/2007 Consumer France
Primary
Concomitant
Blood Glucose Increased Other Serious 71 Female 2/27/2007 United States
Primary
Concomitant
Syncope Other Serious 2/9/2007 57 Female 2/26/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 75 Male 3/7/2007 Consumer United States
Primary
Concomitant
Post Procedural Complication Hospitalization 1/1/2006 62 Female 198 lb 3/19/2007 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 3/20/2007 Consumer Germany
Primary
Concomitant
Hyperkalaemia Hospitalization 6/19/2005 63 Male 3/26/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Haematemesis Other Serious 5/2/2006 Male 3/27/2007 Germany
Primary
Concomitant
Urticaria Other Serious 1/20/2007 63 Male 337 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 3/23/2007 83 Female 4/3/2007 Consumer United States
Primary
Concomitant
Haematemesis Other Serious 5/2/2006 Male 157 lb 4/4/2007 Germany
Primary
Concomitant
Myocardial Ischaemia Hospitalization 9/28/2006 Female 115 lb 4/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 3/23/2007 83 Female 4/16/2007 Consumer United States
Primary
Concomitant
Death Hospitalization 4/4/2007 Male 171 lb 4/16/2007 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/12/2006 80 Male 162 lb 3/23/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Female 4/30/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/26/2007 74 Male 198 lb 1/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 11/9/2006 61 Male 190 lb 11/13/2006 Pharmacist United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 5/8/2007 Consumer Germany
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 63 Male 5/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 3/1/2007 Female 149 lb 5/14/2007 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 3/22/2007 Male 153 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Musculoskeletal Stiffness Life Threatening 4/23/2007 83 Female 5/15/2007 Finland
Primary
Concomitant
Fatigue Hospitalization 2/20/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neuralgia Hospitalization 1/1/2003 61 Female 5/24/2007 Consumer United States
Primary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Hospitalization 12/10/2006 53 Female 6/14/2007 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Rhinorrhoea 72 Male 170 lb 6/22/2007 United States
Primary
Concomitant
Renal Failure Acute Other Serious 61 Male 6/26/2007 Other Health Professional Finland
Primary
Secondary
Weight Increased Other Serious Male 6/27/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 61 Male 7/3/2007 Other Health Professional Finland
Primary
Concomitant
Oral Mucosal Blistering 5/1/2007 47 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2006 76 Female 6/22/2007 Denmark
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 7/10/2007 Consumer United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 84 Female 7/6/2007 Germany
Primary
Secondary
Concomitant
Pulmonary Infarction Other Serious 3/1/2007 64 Male 7/12/2007 Physician Sweden
Primary
Concomitant
Sarcoma Hospitalization 5/20/2003 Male 7/24/2007 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2007 64 Male 7/26/2007 Physician Sweden
Primary
Concomitant
Angioedema Hospitalization 7/22/2007 52 Male 7/24/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 6/26/2007 55 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/26/2007 55 Male 8/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Cancer Other Serious 7/1/2007 73 Male 8/2/2007 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/1/2007 55 Male 8/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vomiting Other Serious 3/23/2007 83 Female 138 lb 8/3/2007 Consumer United States
Primary
Concomitant
Subcutaneous Haematoma Death 5/12/2007 86 Female 8/6/2007 Physician Sweden
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 6/26/2007 55 Male 7/25/2007 United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 5/25/2006 71 Female 8/3/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 240 lb 8/10/2007 Physician United States
Primary
Concomitant
Angioedema Other Serious 7/1/2007 Female 8/20/2007 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 Male 9/4/2007 Germany
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 9/4/2007 Other Health Professional Philippines
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/16/2006 81 Female 9/7/2007 United States
Primary
Secondary
Concomitant
Weight Increased 52 Female 227 lb 9/18/2007 Consumer United States
Primary
Concomitant
Back Pain 3/1/2007 Male 291 lb 9/20/2007 Consumer United States
Primary
Concomitant
Paraesthesia 60 Male 196 lb 9/20/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 10/5/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 10/19/2007 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 10/30/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/22/2007 80 Male 180 lb 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 11/23/2007 United States
Primary
Concomitant
Sneezing Hospitalization 7/12/2007 Female 208 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Haemoconcentration Other Serious 8/16/2007 60 Male 11/16/2007 Russian Federation
Primary
Secondary
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 11/30/2007 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 12/10/2007 United States
Primary
Concomitant
Oedema Peripheral Male 170 lb 12/14/2007 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/26/2007 74 Male 12/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2006 65 Male 222 lb 12/7/2007 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 6/1/2007 88 Female 5/21/2008 Other Health Professional Sweden
Primary
Concomitant
Oedema Peripheral 4/1/2008 82 Female 6/13/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/1/2008 73 Female 148 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Po2 Decreased Hospitalization 8/1/2007 84 Male 205 lb 6/17/2008 United States
Primary
Secondary
Concomitant
Pruritus Generalised 75 Male 7/1/2008 Consumer United States
Primary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 7/3/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 7/20/2008 41 Female 8/4/2008 Germany
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/19/2008 56 Female 8/7/2008 Pharmacist Colombia
Primary
Concomitant
Tachycardia Hospitalization 7/15/2007 Female 8/6/2008 Physician Germany
Primary
Concomitant
Subdural Haematoma Other Serious 12/20/2006 8/8/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 267 lb 8/11/2008 Consumer United States
Primary
Secondary
Concomitant
Obstructive Airways Disorder Other Serious 66 Male 8/8/2007 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 8/13/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/1/2008 70 Male 131 lb 8/26/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 75 Male 162 lb 10/14/2008 United States
Primary
Secondary
Concomitant
Memory Impairment Required Intervention 3/1/2008 52 Female 158 lb 10/16/2008 Consumer United States
Primary
Concomitant
Sepsis Death 9/26/2008 Female 10/27/2008 Other Health Professional Norway
Primary
Concomitant
Platelet Count Decreased Other Serious 10/13/2008 53 Male 170 lb 10/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Memory Impairment Other Serious 3/1/2008 52 Female 185 lb 11/5/2008 Other Health Professional United States
Primary
Concomitant
Pruritus 9/1/2008 Female 11/26/2008 Physician United States
Primary
Concomitant
Pruritus 11/26/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/12/2008 Physician Germany
Primary
Secondary
Concomitant
Somnolence 9/1/2008 Female 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 11/3/2008 Male 12/12/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 12/29/2008 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 2/29/2008 1/21/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Paraesthesia 11/15/2008 Male 2/24/2009 United States
Primary
Concomitant
Rectal Polyp Hospitalization 1/30/2009 Male 3/4/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/28/2007 Male 176 lb 3/16/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 1/30/2009 77 Male 183 lb 3/26/2009 Physician Germany
Primary
Secondary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 4/7/2009 United States
Primary
Concomitant
Dizziness Hospitalization 11/6/2008 54 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Ventricular Fibrillation Death 3/13/2009 Male 4/21/2009 Pharmacist Colombia
Primary
Secondary
Urticaria Hospitalization 12/5/2007 68 Female 229 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Haematoma Hospitalization 11/19/2008 75 Female 5/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/12/2009 Female 130 lb 5/29/2009 United States
Primary
Concomitant
Unevaluable Event Death 71 Male 5/28/2009 United States
Primary
Concomitant
Small For Dates Baby Life Threatening Female 3 lb 5/30/2009 Physician Sweden
Primary
Concomitant
Twin Pregnancy Disability Female 3 lb 5/29/2009 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/12/2009 Female 130 lb 6/3/2009 United States
Primary
Concomitant
Death Death 5/27/2009 Male 240 lb 6/3/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/12/2009 Female 130 lb 6/10/2009 United States
Primary
Concomitant
Pleural Effusion Other Serious 11/21/2008 70 Female 148 lb 6/11/2009 Physician Germany
Primary
Concomitant
Coronary Artery Disease Death 5/27/2009 Male 240 lb 6/10/2009 Physician United States
Primary
Concomitant
Uhthoff's Phenomenon Hospitalization 10/6/2008 38 Male 6/12/2009 Physician Germany
Primary
Concomitant
Pneumonia Other Serious 12/1/2008 Female 180 lb 6/15/2009 United States
Primary
Concomitant
Renal Injury Other Serious 3/21/2009 Female 168 lb 6/18/2009 United States
Primary
Concomitant
Hypoaesthesia Hospitalization 11/5/2008 Female 6/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms 85 Female 6/19/2009 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 70 Male 6/22/2009 Other Health Professional Netherlands
Primary
Concomitant
Wheezing Hospitalization 77 Male 6/18/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/5/2009 68 Male 6/19/2009 Other Health Professional Colombia
Primary
Secondary
Concomitant
Anaemia Macrocytic Hospitalization 4/28/2009 49 Female 6/25/2009 Consumer Australia
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/1/2008 Female 180 lb 6/25/2009 United States
Primary
Concomitant
Cardiac Failure Death Female 250 lb 6/26/2009 Physician United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2008 Female 233 lb 6/29/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/21/2009 Female 168 lb 6/29/2009 United States
Primary
Concomitant
Peritoneal Haemorrhage Life Threatening 5/23/2009 71 Male 6/26/2009 Physician United States
Primary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant

Drug Data