Metoprolol Succinate combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Personality Change Other Serious 1/1/2004 62 Male 4/7/2006 Consumer United States
Primary
Concomitant
Personality Change Other Serious 1/1/2004 62 Male 5/9/2006 Consumer United States
Primary
Concomitant
Transaminases Increased Hospitalization 3/1/2006 77 Female 5/22/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2006 77 Female 6/22/2006 Other Health Professional Sweden
Primary
Concomitant
Interacting
Pneumonia Hospitalization 11/1/2006 58 Male 188 lb 11/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Stress Other Serious 1/1/2006 79 Female 78 lb 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 1/2/2007 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/9/2006 77 Male 1/2/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 9/1/2004 73 Male 185 lb 1/12/2007 Consumer United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/14/2007 87 Female 138 lb 1/19/2007 United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 1/25/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 200 lb 2/6/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/30/2007 70 Male 2/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 3/26/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/15/2007 77 Female 190 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Iritis Other Serious Female 4/4/2007 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 82 Female 121 lb 4/6/2007 Physician Germany
Primary
Concomitant
Pain Hospitalization 3/23/2006 Female 145 lb 4/9/2007 Consumer United States
Primary
Concomitant
Pain Hospitalization 3/23/2006 Female 145 lb 4/19/2007 Physician United States
Primary
Concomitant
Joint Swelling Other Serious 4/8/2007 65 Female 120 lb 4/24/2007 Physician Canada
Primary
Concomitant
Thrombosis Other Serious 3/1/2007 82 Female 121 lb 5/1/2007 Physician Germany
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 5/4/2007 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 3/8/2006 Female 121 lb 5/17/2007 Physician Germany
Primary
Concomitant
Personality Change Other Serious 1/1/2004 62 Male 5/24/2007 Consumer United States
Primary
Secondary
Concomitant
Visual Disturbance 12/27/2006 62 Female 2/22/2007 United States
Primary
Concomitant
Wound Dehiscence Other Serious 3/8/2006 Female 121 lb 6/15/2007 Physician Germany
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2007 Male 364 lb 6/18/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 6/21/2007 United States
Primary
Concomitant
Pruritus 1/1/2007 81 Male 162 lb 6/22/2007 United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 6/22/2007 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 3/5/2007 75 Male 195 lb 6/26/2007 Pharmacist United States
Primary
Concomitant
Coma Other Serious Female 7/13/2007 United States
Primary
Concomitant
Pharmaceutical Product Complaint 3/22/2007 64 Male 8/9/2007 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 1/1/2004 62 Male 233 lb 8/21/2007 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 4/5/2007 81 Female 133 lb 7/25/2007 United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 7/21/2006 53 Male 150 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Coma Other Serious Female 8/29/2007 United States
Primary
Concomitant
Pemphigoid Other Serious 2/1/2006 Male 9/4/2007 Consumer Netherlands
Primary
Secondary
Flatulence 7/1/2007 Female 9/7/2007 Consumer United States
Primary
Concomitant
Tongue Disorder Hospitalization 4/26/2007 78 Male 375 lb 9/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Visual Disturbance 5/1/2007 84 Male 9/13/2007 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization Male 9/17/2007 Consumer United States
Primary
Concomitant
Coronary Artery Disease Other Serious 9/12/2007 Female 287 lb 9/12/2007 Physician United States
Primary
Concomitant
Drug Effect Decreased 8/17/2007 Male 9/18/2007 Pharmacist United States
Primary
Concomitant
Osteoporotic Fracture Other Serious 8/21/2007 Male 4/21/2008 Physician Germany
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 67 Male 4/22/2008 Consumer United States
Primary
Concomitant
Lymphoma Other Serious 68 Female 4/25/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea Female 5/12/2008 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 67 Male 5/13/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/29/2008 67 Male 4/30/2008 Physician Norway
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2008 Female 98 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea Female 5/30/2008 Consumer United States
Primary
Concomitant
Throat Irritation Female 6/23/2008 Pharmacist United States
Primary
Concomitant
Pneumonia 1/1/2007 Female 7/2/2008 Consumer United States
Primary
Concomitant
Dysphonia 9/1/2007 79 Male 7/7/2008 Consumer United States
Primary
Concomitant
Increased Upper Airway Secretion 5/29/2008 Male 7/7/2008 Consumer United States
Primary
Concomitant
Retinal Detachment Hospitalization Male 7/21/2008 Consumer United States
Primary
Secondary
Concomitant
Throat Irritation Female 7/29/2008 Pharmacist United States
Primary
Concomitant
Rhinitis Allergic Other Serious 5/1/2008 Female 163 lb 8/11/2008 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 7/4/2008 Female 8/13/2008 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 67 Male 8/19/2008 Physician United States
Primary
Concomitant
Musculoskeletal Disorder Hospitalization 1/1/2007 81 Female 9/10/2008 Consumer
Primary
Concomitant
Hypovolaemia Hospitalization 9/23/2008 Male 174 lb 10/6/2008 Physician United States
Primary
Concomitant
Urinary Retention 7/1/2007 Male 212 lb 10/28/2008 Consumer
Primary
Concomitant
Tachycardia Hospitalization 9/23/2008 Male 174 lb 10/30/2008 Physician United States
Primary
Concomitant
Throat Irritation Female 11/12/2008 Pharmacist
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 1/1/2008 78 Male 2/5/2009 Physician Germany
Primary
Secondary
Concomitant
Rectal Polyp Hospitalization 1/30/2009 Male 3/4/2009 Consumer United States
Primary
Concomitant
Urticaria 8/17/2007 Male 3/5/2009 Pharmacist
Primary
Concomitant
Dry Mouth 2/1/2009 Male 4/22/2009 Consumer
Primary
Concomitant
Lung Neoplasm Malignant Death 1/1/2008 Male 4/23/2009 Consumer
Primary
Concomitant
Tongue Ulceration 3/1/2009 Male 5/12/2009 Consumer
Primary
Concomitant
Tongue Ulceration 3/1/2009 Male 5/21/2009 Consumer
Primary
Concomitant
Throat Irritation 4/28/2009 Male 5/26/2009 Consumer
Primary
Concomitant
Throat Irritation 4/28/2009 Male 6/1/2009 Consumer
Primary
Concomitant
Throat Irritation 4/28/2009 Male 6/10/2009 Consumer
Primary
Concomitant
Unresponsive To Stimuli Death 12/21/2008 45 Female 104 lb 6/8/2009 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/1/2007 Female 225 lb 6/11/2009 United States
Primary
Concomitant
Swelling Face Other Serious 5/20/2009 Female 6/15/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/6/2009 Male 222 lb 6/19/2009 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 11/27/2008 77 Female 183 lb 6/16/2009 Pharmacist United States
Primary
Concomitant
Dysphonia 65 Male 173 lb 6/23/2009 Consumer United States
Primary
Secondary
Concomitant
Cough 6/1/2009 68 Female 6/23/2009 Consumer
Primary
Concomitant
Tongue Ulceration 3/1/2009 51 Male 264 lb 6/25/2009 Other Health Professional
Primary
Concomitant
Swelling Face 4/12/2009 78 Male 6/30/2009 Consumer United States
Primary
Concomitant
Anaemia Other Serious 5/1/2009 Female 7/2/2009 Consumer United States
Primary
Concomitant
Wound Secretion Hospitalization 62 Female 7/12/2009 United States
Primary
Concomitant
Rectal Haemorrhage 1/1/2009 Male 306 lb 7/16/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Female 7/19/2009 Lawyer United States
Primary
Concomitant
Somnolence Hospitalization 9/1/2007 Female 7/23/2009 Physician United States
Primary
Concomitant
Enteritis Hospitalization 7/14/2009 Male 170 lb 7/21/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Required Intervention Female 240 lb 7/26/2009 Consumer United States
Primary
Concomitant
Dyspnoea Female 8/6/2009 Consumer
Primary
Concomitant
Weight Decreased Death 75 Female 7/31/2009 Lawyer United States
Primary
Concomitant
Dyspnoea 7/29/2009 Female 8/13/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Drug Ineffective 5/1/2009 Male 9/29/2009 Consumer
Primary
Concomitant
Respiratory Failure Life Threatening 10/26/2007 Female 9/29/2009 Consumer
Primary
Concomitant
Vomiting Hospitalization 63 Male 180 lb 9/25/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 10/13/2007 Male 10/8/2009 Japan
Primary
Concomitant
Unevaluable Event Hospitalization 64 Male 201 lb 11/18/2009 United States
Primary
Concomitant
Osteoporotic Fracture Other Serious 8/21/2007 Male 12/1/2009 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 9/23/2008 Male 174 lb 12/1/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 12/1/2009 Female 1/31/2010 Other Health Professional Canada
Primary
Concomitant
Visual Impairment Other Serious 11/3/2009 Male 186 lb 3/16/2010 United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 3/23/2010 75 Male 216 lb 4/6/2010 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 12/1/2009 69 Male 202 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/1/2009 60 Female 198 lb 5/7/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2009 79 Male 141 lb 6/2/2010 United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 12/6/2009 79 Male 189 lb 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 9/1/2007 74 Female 7/27/2010 Consumer
Primary
Concomitant
Nausea Other Serious 1/1/2009 Female 5/18/2010 United States
Primary
Concomitant
Right Ventricular Systolic Pressure Increased Hospitalization 12/6/2009 79 Male 189 lb 8/13/2010 Physician United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 7/6/2010 73 Female 8/26/2010 Physician United States
Primary
Concomitant
Sepsis Death 8/11/2010 77 Male 9/8/2010 Consumer France
Primary
Secondary
Sepsis Death 8/11/2010 77 Male 9/23/2010 Consumer France
Primary
Secondary
Sepsis Death 8/11/2010 77 Male 10/7/2010 Consumer France
Primary
Concomitant
Presyncope Other Serious 9/1/2010 75 Female 106 lb 10/10/2010 Consumer Brazil
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/9/2010 Male 10/5/2010 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 8/11/2010 81 Male 189 lb 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Chest Pain 10/11/2010 72 Male 10/22/2010 Consumer
Primary
Concomitant
Rhinorrhoea Other Serious Female 168 lb 10/22/2010 Physician United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 8/11/2010 81 Male 189 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 10/15/2010 68 Female 154 lb 11/3/2010 Other Health Professional Denmark
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/1/2010 70 Female 11/24/2010 Other Health Professional Canada
Primary
Concomitant
Rib Fracture Other Serious Male 11/24/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/8/2010 79 Female 12/2/2010 Consumer
Primary
Concomitant
Visual Impairment Other Serious Female 11/30/2010 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization 11/8/2010 65 Male 205 lb 12/3/2010 Physician Germany
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious Female 12/14/2010 Consumer Netherlands
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/15/2010 71 Female 145 lb 12/2/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/15/2010 71 Female 145 lb 12/13/2010 Physician United States
Primary
Concomitant
Blood Test Abnormal Hospitalization Female 122 lb 12/29/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 12/1/2010 75 Female 122 lb 2/15/2011 Physician United States
Primary
Concomitant
Laryngeal Cancer Hospitalization 5/25/2004 78 Male 2/25/2011 Consumer United States
Primary
Concomitant
Sudden Death Hospitalization 1/1/2010 73 Male 176 lb 3/8/2011 Physician Germany
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/1/2010 74 Male 176 lb 3/14/2011 Physician Germany
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 2/14/2011 63 Male 247 lb 3/14/2011 Other Health Professional Germany
Primary
Concomitant
Atrial Flutter Hospitalization 11/12/2009 67 Female 273 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea 78 Male 3/16/2011 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 12/22/2010 62 Male 3/17/2011 Consumer Spain
Primary
Secondary
Concomitant
Interacting
Cardiac Failure Congestive Hospitalization 7/1/2009 82 Female 151 lb 3/3/2011 Other Health Professional United States
Primary
Concomitant
Drug Effect Decreased Male 3/18/2011 Consumer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 61 Male 3/21/2011 Lawyer United States
Primary
Concomitant
Skin Hypertrophy Disability 10/24/2005 67 Male 153 lb 3/21/2011 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Failure Life Threatening 2/14/2011 63 Male 247 lb 3/24/2011 Other Health Professional Germany
Primary
Concomitant
Haemorrhage Hospitalization 87 Male 4/7/2011 United States
Primary
Concomitant

Drug Data