Metoprolol Succinate combined with Nitroglycerin

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 7/1/2003 78 Male 3/3/2006 Other Health Professional Norway
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 2/1/2006 85 Male 5/15/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 2/1/2006 85 Male 5/16/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Priapism Other Serious 3/22/2006 72 Male 184 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Required Intervention 1/11/2006 76 Male 118 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 55 Male 5/26/2006 United States
Primary
Concomitant
Rash Other Serious 2/23/2006 55 Female 6/5/2006 Physician Hungary
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious 2/15/2006 83 Male 230 lb 4/28/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2006 Male 210 lb 8/24/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2006 Male 210 lb 9/11/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/1/2006 70 Male 11/10/2006 Other Health Professional United States
Primary
Secondary
Haematoma Other Serious 8/12/2005 83 Male 11/20/2006 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/10/2006 75 Male 231 lb 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 10/3/2006 92 Female 11/20/2006 Physician United States
Primary
Concomitant
Hallucination Other Serious 7/26/2006 70 Male 208 lb 8/15/2006 Physician United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 12/4/2006 Physician Germany
Primary
Concomitant
Loss Of Consciousness Death 54 Male 12/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomach Discomfort Death 88 Female 176 lb 12/8/2006 Physician Canada
Primary
Concomitant
Lymphocytic Lymphoma Other Serious 5/17/2005 Male 164 lb 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/1/2006 69 Female 12/14/2006 Consumer United States
Primary
Concomitant
Secondary Hypertension Other Serious 64 Female 12/19/2006
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/6/2006 58 Male 182 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/15/2006 84 Male 128 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 12/19/2006 Male 245 lb 12/28/2006 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 8/12/2006 79 Male 12/29/2006 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 8/12/2006 79 Male 12/29/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2004 Male 214 lb 12/29/2006 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 8/15/2006 64 Male 249 lb 12/29/2006 Pharmacist United States
Primary
Concomitant
Peritoneal Haemorrhage Life Threatening 1/1/2007 78 Male 202 lb 1/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 9/21/2006 Male 150 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 1/12/2007 Physician Germany
Primary
Concomitant
Hypotension Required Intervention 7/30/2004 49 Male 3/6/2006 United States
Primary
Secondary
Concomitant
Pericardial Haemorrhage Life Threatening 11/7/2005 Male 181 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 6/2/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Drug Level Below Therapeutic Other Serious 12/1/2006 Male 173 lb 1/22/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 10/18/2006 48 Female 1/22/2007 Consumer United States
Primary
Concomitant
Rash Generalised Hospitalization 11/27/2006 Male 216 lb 12/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 7/6/2006 Male 170 lb 2/15/2007 Netherlands
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 11/6/2006 55 Male 164 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/25/2007 62 Male 242 lb 2/8/2007 United States
Primary
Concomitant
Angioedema Hospitalization 10/20/2006 64 Male 2/16/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/12/2007 76 Male 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Arrhythmia Hospitalization 42 Male 2/23/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/9/2004 176 lb 2/23/2007 Physician Germany
Primary
Concomitant
Umbilical Hernia Other Serious 11/15/2006 72 Male 2/15/2007 Physician Germany
Primary
Concomitant
Vascular Injury 11/15/2006 72 Male 2/15/2007 Physician Germany
Primary
Concomitant
White Blood Cells Urine Positive Other Serious 6/27/2006 81 Female 2/28/2007 Consumer Norway
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/1/2007 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/1/2005 52 Female 150 lb 3/7/2007 Physician United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 3/13/2007 Physician Germany
Primary
Concomitant
Hypotension Other Serious 1/10/2007 81 Male 218 lb 3/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pallor Other Serious 1/7/2007 Male 224 lb 3/16/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Other Serious 3/12/2007 Male 190 lb 3/27/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/15/2007 77 Female 190 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Stridor Disability 1/30/2007 75 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/25/2007 62 Male 245 lb 3/26/2007 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 3/9/2007 89 Male 156 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/23/2007 83 Female 4/3/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/19/2006 54 Male 210 lb 12/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 3/29/2007 Physician Canada
Primary
Concomitant
Shock Other Serious 10/6/2004 Male 4/6/2007 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/23/2007 83 Female 4/16/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2007 75 Male 4/17/2007 Pharmacist Netherlands
Primary
Concomitant
Gout Hospitalization 2/7/2007 Female 250 lb 4/17/2007 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 2/9/2007 72 Male 4/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue Hospitalization 72 Male 4/19/2007
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/1/2007 56 Male 148 lb 4/17/2007 Physician Canada
Primary
Concomitant
Urticaria Life Threatening 3/1/2006 65 Male 241 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 4/7/2007 82 Female 4/17/2007 Pharmacist United States
Primary
Concomitant
Shock Other Serious 10/6/2004 Male 4/26/2007 Lawyer United States
Primary
Concomitant
Skin Discolouration Other Serious 11/5/2006 Female 4/27/2007 Consumer Canada
Primary
Concomitant
Fatigue Hospitalization 72 Male 4/27/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/26/2007 74 Male 198 lb 1/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 11/9/2006 61 Male 190 lb 11/13/2006 Pharmacist United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/1/2007 Physician Germany
Primary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2007 75 Male 5/7/2007 Pharmacist Netherlands
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2007 75 Male 5/10/2007 Pharmacist Netherlands
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/11/2007 Physician Germany
Primary
Concomitant
Stent Placement Hospitalization 42 Male 5/22/2007 Consumer United States
Primary
Concomitant
Septic Shock Life Threatening 9/1/2006 69 Male 198 lb 5/22/2007 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/4/2006 79 Female 150 lb 5/23/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/3/2007 75 Male 5/29/2007 Pharmacist Netherlands
Primary
Concomitant
Chest Pain Hospitalization 8/24/2006 88 Female 5/25/2007 United States
Primary
Secondary
Concomitant
Irritable Bowel Syndrome 2/10/2007 62 Female 277 lb 5/17/2007 Other Health Professional United States
Primary
Concomitant
Tinnitus Hospitalization 3/1/2007 83 Male 6/7/2007 Canada
Primary
Concomitant
Shock Other Serious 6/23/2004 Male 6/15/2007 Lawyer United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 8/29/2006 56 Female 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 2/28/2007 69 Male 6/19/2007 United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Dizziness Hospitalization 4/26/2007 79 Male 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 6/28/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/4/2007 Physician Germany
Primary
Secondary
Concomitant
Vith Nerve Paralysis Hospitalization 6/13/2007 73 Female 6/29/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 42 Male 7/9/2007 Consumer United States
Primary
Concomitant
Vith Nerve Paralysis Hospitalization 6/13/2007 73 Female 7/6/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 64 Male 198 lb 7/13/2007
Primary
Secondary
Concomitant
Vascular Graft Other Serious 1/1/1993 72 Female 205 lb 7/17/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Rash Required Intervention 7/9/2007 47 Female 188 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 7/18/2007 Physician Canada
Primary
Concomitant
Syncope Other Serious 1/7/2007 Male 224 lb 7/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Shock Syndrome Death 10/28/2004 84 Male 8/2/2007 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 7/12/2007 84 Male 142 lb 8/2/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 3/23/2007 83 Female 138 lb 8/3/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 6/18/2006 74 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 6/1/2007 40 Male 238 lb 8/10/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 7/17/2007 83 Male 8/17/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 4/7/2007 82 Female 8/16/2007 Pharmacist United States
Primary
Concomitant
Death Hospitalization 7/30/2007 Male 8/24/2007 Physician United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/1/2007 Male 165 lb 9/6/2007 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasticity Other Serious 1/1/2007 Female 177 lb 9/10/2007 United States
Primary
Secondary
Concomitant
Hypotension Disability 4/16/2002 Male 190 lb 9/11/2007 Canada
Primary
Secondary
Concomitant
Pancytopenia Other Serious 7/14/2007 Male 146 lb 9/13/2007 United States
Primary
Concomitant
Nausea Other Serious 9/1/2007 54 Female 120 lb 9/20/2007 Consumer United States
Primary
Concomitant
Headache 2/15/2007 51 Male 280 lb 9/20/2007 Consumer United States
Primary
Concomitant
Back Pain 86 Male 179 lb 9/20/2007 Consumer United States
Primary
Concomitant
Rash 81 Male 249 lb 9/20/2007 Consumer United States
Primary
Concomitant
Neck Pain Hospitalization 7/11/2007 58 Female 267 lb 9/20/2007 Consumer United States
Primary
Concomitant
Breath Odour 7/1/2007 Male 8/6/2007 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 7/18/2007 47 Female 126 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Life Threatening 7/18/2007 47 Female 11/6/2007 United States
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/4/2006 Male 246 lb 11/9/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/26/2007 74 Male 12/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 1/1/1994 Male 201 lb 12/18/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 69 Female 154 lb 12/27/2007 Physician Germany
Primary
Secondary
Concomitant
Macular Degeneration Other Serious Female 6/9/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/10/2007 60 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 86 Male 6/24/2008 United States
Primary
Secondary
Diarrhoea 4/1/2007 Female 7/2/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/8/2008 Male 321 lb 7/2/2008 Physician United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 11/6/2006 Male 162 lb 7/3/2008 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 87 Female 7/7/2008 Consumer Norway
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/1/2008 53 Male 7/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 4/1/2008 Male 321 lb 7/10/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/18/2008 67 Male 187 lb 7/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Viral Infection Hospitalization 6/1/2008 Female 145 lb 8/5/2008 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/14/2004 Female 8/7/2008 Physician Germany
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 6/1/2008 53 Male 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 4/1/2007 Male 233 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 12/20/2006 8/8/2008 Consumer United States
Primary
Secondary
Concomitant
Obstructive Airways Disorder Other Serious 66 Male 8/8/2007 Other Health Professional United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 1/1/2006 152 lb 8/11/2008 Other Health Professional United States
Primary
Concomitant
Death Death 7/26/2008 Female 8/13/2008 Physician United States
Primary
Concomitant
Peritonitis Life Threatening 6/6/2008 Male 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia 9/26/2007 Male 231 lb 8/27/2008 Physician United States
Primary
Concomitant
Insomnia 1/1/2006 Male 8/27/2008 Consumer United States
Primary
Concomitant