Metoprolol Succinate combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Nausea Other Serious 9/1/2005 76 Male 173 lb 12/27/2005 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 6/21/2005 65 Female 4/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Burning Sensation Other Serious Female 4/18/2006 Other Health Professional Canada
Primary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2006 36 Male 210 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Rash Pustular Hospitalization 11/6/2006 54 Male 11/21/2006 Physician Sweden
Primary
Concomitant
Renal Impairment Life Threatening 10/26/2005 75 Female 105 lb 11/20/2006 Pharmacist United States
Primary
Concomitant
Hallucination Other Serious 7/26/2006 70 Male 208 lb 8/15/2006 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 11/30/2006 71 Male 252 lb 12/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/26/2006 67 Female 130 lb 12/5/2006 Physician Sweden
Primary
Concomitant
Procedural Complication Life Threatening 12/8/2006 Female 118 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Splenic Infarction Required Intervention 4/19/2006 Male 12/15/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/9/2006 77 Male 1/2/2007 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 8/15/2006 Female 160 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Subclavian Vein Thrombosis Life Threatening 10/17/2006 43 Female 155 lb 10/22/2006 United States
Primary
Concomitant
Hypotension Required Intervention 7/30/2004 49 Male 3/6/2006 United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 2/2/2007 80 Female 146 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 11/6/2006 55 Male 164 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Sinus Arrhythmia Hospitalization 42 Male 2/23/2007 United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Other Serious 2/5/2007 67 Female 3/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tinnitus Hospitalization 3/1/2007 83 Male 3/26/2007 Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/3/2007 59 Female 187 lb 4/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Rupture Other Serious 2/22/2007 70 Male 176 lb 4/17/2007
Primary
Secondary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Intestinal Ischaemia Required Intervention 3/19/2007 Female 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Anaemia Hospitalization 10/4/2006 48 Male 4/30/2007 Pharmacist United States
Primary
Concomitant
Tinnitus Hospitalization 3/1/2007 83 Male 6/7/2007 Canada
Primary
Concomitant
Weight Decreased Hospitalization 4/14/2007 78 Male 6/6/2007 Physician Canada
Primary
Secondary
Concomitant
Joint Effusion Hospitalization 7/8/2006 72 Male 6/19/2007 Other Health Professional Netherlands
Primary
Concomitant
Wound Infection Bacterial Other Serious 26 Female 7/12/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 70 Female 6/29/2007 Physician Netherlands
Primary
Secondary
Concomitant
Urethral Polyp Hospitalization 60 Female 8/6/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 7/22/2007 53 Female 174 lb 8/3/2007 Other Health Professional United States
Primary
Concomitant
Rash Pustular Hospitalization 11/6/2006 Male 8/17/2007 Physician Sweden
Primary
Concomitant
Methaemoglobinaemia Hospitalization 57 Male 8/20/2007
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 6/10/2007 Male 201 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 5/1/2007 62 Male 9/10/2007 Consumer United States
Primary
Concomitant
Back Pain 3/1/2007 Male 291 lb 9/20/2007 Consumer United States
Primary
Concomitant
Transplant Failure Hospitalization 12/13/2007 53 Male 225 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Other Serious 44 Male 3/7/2008
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 1/31/2008 Female 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Lymphoma Other Serious 68 Female 4/25/2008 Other Health Professional United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2008 Female 98 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Death 6/9/2008 Male 6/18/2008 Pharmacist United States
Primary
Concomitant
Swollen Tongue Life Threatening 6/8/2008 81 Male 222 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Overdose Other Serious 1/1/2006 Female 6/30/2008 Consumer United States
Primary
Concomitant
Somnolence Other Serious 6/1/2008 Female 155 lb 7/8/2008 Consumer United States
Primary
Concomitant
Heart Rate Decreased Other Serious 36 Female 7/9/2008 Other Health Professional India
Primary
Concomitant
Interacting
Vomiting Death 7/15/2008 Male 192 lb 7/25/2008 Physician United States
Primary
Concomitant
Vomiting Death 7/24/2008 Male 192 lb 7/25/2008 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 38 Male 8/7/2008
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 4/1/2007 Male 233 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Retention 3/10/2008 Female 206 lb 9/12/2008 Consumer United States
Primary
Concomitant
Dyspnoea Life Threatening 11/20/2008 65 Male 203 lb 11/25/2008 Consumer United States
Primary
Secondary
Concomitant
Hypophagia Hospitalization 10/16/2008 70 Male 12/8/2008 Germany
Primary
Secondary
Concomitant
Faecaloma Hospitalization 10/16/2008 70 Male 12/11/2008 Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/2/2009 Female 122 lb 2/21/2009 Physician United States
Primary
Secondary
Concomitant
Tachyarrhythmia Life Threatening 10/23/2008 74 Male 181 lb 3/4/2009 Physician Germany
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/2/2009 Female 122 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Tachycardia Death 1/24/2009 Male 157 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Device Failure Other Serious 4/6/2007 61 Male 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Middle Ear Effusion Required Intervention 5/18/2009 Female 107 lb 6/3/2009 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 2/1/2009 59 Female 179 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Death Female 250 lb 6/26/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/27/2006 59 Male 215 lb 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Faecaloma Hospitalization 10/16/2008 70 Male 6/30/2009 Physician Germany
Primary
Secondary
Concomitant
Hypophagia Hospitalization 10/16/2008 70 Male 7/6/2009 Physician Germany
Primary
Secondary
Concomitant
Faecaloma Hospitalization 10/16/2008 70 Male 7/17/2009 Germany
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Other Serious 1/1/2008 Female 238 lb 7/22/2009 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 10/1/2003 37 Female 225 lb 7/24/2009 United States
Primary
Concomitant
Myocarditis Life Threatening 6/1/2009 Female 144 lb 8/5/2009 United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 10/1/2005 54 Male 8/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 76 Male 9/15/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/29/2007 Female 130 lb 9/30/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 12/1/2006 Female 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 11/1/2003 52 Male 212 lb 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 12/1/2006 43 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 12/1/2006 43 Female 5/5/2010 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Female 179 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Melaena Hospitalization 5/16/2007 73 Female 187 lb 6/23/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/29/2009 61 Male 6/23/2010 Physician Canada
Primary
Concomitant
Troponin I Increased Hospitalization 1/1/2010 70 Female 172 lb 6/28/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/14/2002 38 Female 370 lb 7/23/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/6/2010 61 Female 146 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 3/23/2008 66 Male 190 lb 7/27/2010 Lawyer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2010 52 Male 251 lb 7/27/2010 Other Health Professional Canada
Primary
Concomitant
Syncope Hospitalization 5/6/2010 61 Female 146 lb 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/1/2008 54 Female 179 lb 8/12/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 8/14/2002 38 Female 370 lb 8/18/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 5/24/2007 60 Male 139 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 50 Male 161 lb 8/18/2010 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/1/2006 43 Female 10/4/2010 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 5/6/2010 61 Female 146 lb 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 10/19/2010 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 2/23/2010 59 Male 11/25/2010 Physician United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 2/6/2010 57 Female 149 lb 11/26/2010 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 11/27/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization Female 12/2/2010 Physician Netherlands
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 10/13/2010 Female 11/15/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Other Serious 5/1/1994 60 Male 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 12/7/2010 Other Health Professional United States
Primary
Concomitant
Sudden Death Other Serious 9/1/2010 59 Male 143 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Convulsion Other Serious 12/1/2006 43 Female 1/18/2011 Physician United States
Primary
Secondary
Concomitant
Metabolic Syndrome Hospitalization 6/1/2006 47 Female 1/26/2011 Physician United States
Primary
Concomitant
Headache Other Serious 7/1/2008 54 Female 179 lb 2/3/2011 Physician United States
Primary
Concomitant
Pain Other Serious 12/29/2007 81 Male 170 lb 2/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 1/11/2011 76 Male 2/28/2011 Consumer France
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 1/1/2008 59 Male 3/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 12/29/2007 81 Male 170 lb 3/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 8/29/2010 59 Male 143 lb 3/21/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Agitation Hospitalization 2/1/2011 83 Male 3/28/2011 Consumer United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 1/1/2003 39 Female 370 lb 3/28/2011 United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 12/9/2010 3/28/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Angina Unstable Life Threatening 8/29/2010 59 Male 143 lb 3/30/2011 Physician United States
Primary
Concomitant
Interacting
Sudden Death Hospitalization 8/29/2010 59 Male 143 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Renal Failure Other Serious 6/1/2006 68 Male 248 lb 3/31/2011 Consumer United States
Primary
Concomitant
Acute Sinusitis Hospitalization 6/1/2006 47 Female 4/6/2011 Lawyer United States
Primary
Concomitant
Quality Of Life Decreased Death 1/28/2011 75 Male 4/19/2011 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Pain Death 1/1/2004 49 Female 172 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Chest Pain Death 12/23/2010 82 Female 4/28/2011 Pharmacist United States
Primary
Concomitant
Hypokinesia Other Serious Male 154 lb 5/4/2011 Consumer United States
Primary
Concomitant
Angina Pectoris Other Serious 3/28/2006 Female 5/5/2011 United States
Primary
Concomitant
Disability Death 2/9/2004 70 Male 330 lb 5/9/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/29/2010 65 Male 165 lb 5/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/1/2006 43 Female 5/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/1/2007 58 Female 190 lb 5/13/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Life Threatening 11/16/2010 70 Female 164 lb 5/13/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Death 10/5/2006 67 Male 227 lb 5/16/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 62 Male 200 lb 5/16/2011 Lawyer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/29/2010 65 Male 165 lb 5/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cellulitis Hospitalization 7/30/2010 76 Male 251 lb 5/18/2011 Physician United States
Primary
Concomitant
Blood Count Abnormal Other Serious 9/1/2007 61 Female 178 lb 5/23/2011 Physician United States
Primary
Concomitant
Stress Death 1/13/2005 57 Male 229 lb 5/21/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 11/16/2006 85 Male 220 lb 5/24/2011 Other Health Professional United States
Primary
Concomitant
Constipation Hospitalization 7/25/2006 43 Female 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 10/4/2010 47 Male 295 lb 6/8/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/22/2011 54 Male 246 lb 6/10/2011 Other Health Professional Canada
Primary
Concomitant
Pruritus Other Serious 1/1/2003 31 Female 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 10/15/2005 70 Female 174 lb 6/13/2011 Consumer United States
Primary
Concomitant

Drug Data