Metoprolol combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Arrest Death 12/19/2005 83 Male 1/5/2006 Physician
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/19/2005 83 Male 2/1/2006 Physician
Primary
Concomitant
Thrombosis Other Serious 9/1/2004 60 Female 3/1/2006 Physician United States
Primary
Concomitant
Heart Rate Decreased Other Serious 68 Female 178 lb 3/16/2006 United States
Primary
Concomitant
Respiratory Failure Death 2/11/2006 63 Female 346 lb 3/24/2006 Physician Colombia
Primary
Concomitant
Respiratory Failure Death 2/11/2006 63 Female 346 lb 3/27/2006 Physician Colombia
Primary
Concomitant
Hallucination Other Serious 62 Female 3/31/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death 2/11/2006 63 Female 346 lb 3/31/2006 Physician Colombia
Primary
Concomitant
Hallucination Other Serious 62 Female 4/14/2006 Pharmacist United States
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Disease Progression Other Serious 1/1/2006 67 Male 160 lb 11/2/2006 Physician United States
Primary
Concomitant
Nausea Other Serious 8/1/2006 54 Female 130 lb 11/3/2006 Physician United States
Primary
Concomitant
Prostate Infection 1/1/2007 Male 9/24/2007 Consumer United States
Primary
Concomitant
Constipation Other Serious 9/1/2007 146 lb 9/25/2007 United States
Primary
Concomitant
Overdose 6/13/2007 78 Male 7/26/2007 United States
Primary
Secondary
Concomitant
Flatulence 7/11/2007 Female 10/1/2007 Consumer United States
Primary
Concomitant
Visual Disturbance 5/1/2007 84 Male 10/2/2007 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious Female 10/12/2007 United States
Primary
Secondary
Concomitant
Flatulence 7/11/2007 Female 10/18/2007 Consumer United States
Primary
Concomitant
Flatulence 7/11/2007 Female 10/18/2007 Consumer United States
Primary
Concomitant
Flatulence 7/11/2007 Female 10/18/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 Female 108 lb 10/19/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Effect Decreased 8/17/2007 Male 10/23/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 Female 108 lb 10/24/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 2/22/2007 76 Female 10/26/2007 Consumer United States
Primary
Secondary
Concomitant
Prostate Infection 1/1/2007 Male 10/30/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 Female 108 lb 11/1/2007 Consumer United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 11/12/2007 91 Female 106 lb 11/14/2007 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 11/21/2007 United States
Primary
Concomitant
Overdose 6/13/2007 78 Male 10/22/2007 United States
Primary
Secondary
Concomitant
Dyspnoea 8/1/2007 Male 12/10/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Male 12/21/2007 Consumer United States
Primary
Concomitant
Insomnia 10/1/2007 81 Female 1/10/2008 Consumer United States
Primary
Concomitant
Inhibitory Drug Interaction Male 1/14/2008 Consumer United States
Primary
Concomitant
Drug Ineffective Female 4/15/2008 Consumer United States
Primary
Concomitant
Eye Disorder Hospitalization 4/24/2008 61 Female 90 lb 5/29/2008 United States
Primary
Concomitant
Tachycardia Hospitalization 6/4/2008 72 Male 159 lb 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Disorder 5/1/2008 84 Female 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Female 6/15/2008 Consumer United States
Primary
Secondary
Concomitant
Toothache Hospitalization 12/1/2007 71 Female 170 lb 6/16/2008 Physician United States
Primary
Concomitant
Coronary Artery Bypass Other Serious 4/15/2008 77 Male 150 lb 6/16/2008 United States
Primary
Concomitant
Myocardial Infarction Death 5/1/2008 60 Female 163 lb 6/16/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea 2/1/2008 Female 6/26/2008 Consumer United States
Primary
Concomitant
Dysphonia 1/1/2008 84 Male 6/27/2008 Consumer United States
Primary
Concomitant
Rash Pruritic 5/26/2008 77 Female 6/30/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2008 Female 158 lb 7/17/2008 Consumer United States
Primary
Concomitant
Toothache Hospitalization 12/1/2007 71 Female 170 lb 7/22/2008 Physician United States
Primary
Concomitant
Death Death Male 220 lb 7/21/2008 Consumer United States
Primary
Concomitant
Dyspnoea 2/1/2008 Female 8/22/2008 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2008 Female 160 lb 8/22/2008 United States
Primary
Concomitant
Renal Impairment Hospitalization 71 Female 208 lb 9/12/2008 United States
Primary
Concomitant
Drug Ineffective 3/1/2008 Female 9/26/2008 Consumer
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/27/2008 Female 9/29/2008 Consumer
Primary
Concomitant
Toothache Hospitalization 12/1/2007 71 Female 170 lb 11/14/2008 Physician United States
Primary
Concomitant
Vision Blurred 1/1/2007 Female 11/21/2008 Consumer
Primary
Concomitant
Fatigue 10/19/2008 Female 12/2/2008 Consumer
Primary
Concomitant
Dry Mouth 4/1/2008 80 Male 12/19/2008 Consumer United States
Primary
Concomitant
Vision Blurred Female 12/24/2008 Consumer
Primary
Concomitant
Oropharyngeal Pain 8/22/2008 Female 12/30/2008 Consumer
Primary
Concomitant
Weight Increased Hospitalization 12/1/2008 Female 12/31/2008 Consumer
Primary
Concomitant
Myalgia Other Serious 4/15/2008 77 Male 150 lb 1/22/2009 Physician United States
Primary
Concomitant
Toothache Hospitalization 12/1/2007 71 Female 170 lb 1/26/2009 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 10/13/2007 Male 1/29/2009 Japan
Primary
Concomitant
Varicose Vein Ruptured Hospitalization 1/1/2007 Female 1/30/2009 Consumer
Primary
Concomitant
Pain In Extremity Other Serious 4/15/2008 77 Male 150 lb 2/23/2009 Physician United States
Primary
Concomitant
Musculoskeletal Pain Hospitalization Female 3/10/2009 Consumer
Primary
Concomitant
Visual Impairment Hospitalization 81 Male 3/23/2009 United States
Primary
Concomitant
Skin Burning Sensation 12/4/2007 42 Male 189 lb 1/8/2009 United States
Primary
Concomitant
Vomiting Other Serious Male 3/27/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Nausea 43 Male 211 lb 1/8/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 4/15/2008 77 Male 150 lb 3/31/2009 Physician United States
Primary
Concomitant
Tobacco User Other Serious 1/1/2007 Female 220 lb 4/1/2009 Consumer
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Drug Ineffective 12/1/2008 67 Female 4/2/2009 Consumer
Primary
Concomitant
Incorrect Route Of Drug Administration Hospitalization 9/5/2008 72 Female 4/2/2009 Consumer
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Female 161 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Dry Mouth 9/1/2008 Male 4/3/2009 Consumer
Primary
Concomitant
Drug Ineffective 1/1/2009 Male 4/3/2009 Consumer
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/24/2009 Female 137 lb 4/3/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 112 lb 4/3/2009 Canada
Primary
Concomitant
Interacting
Urticaria 8/17/2007 Male 4/6/2009 Pharmacist
Primary
Concomitant
Death Death 3/29/2009 Female 152 lb 4/8/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2008 Male 4/8/2009 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 65 Female 160 lb 4/19/2009 United States
Primary
Concomitant
Dyspnoea 5/2/2009 Female 5/8/2009 Consumer
Primary
Concomitant
Product Quality Issue Hospitalization Female 5/12/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2009 Male 5/12/2009 Consumer
Primary
Concomitant
Visual Impairment Hospitalization 81 Male 5/7/2009 United States
Primary
Concomitant
Dyspnoea Exertional 1/18/2009 Male 5/13/2009 Consumer
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/24/2009 Female 137 lb 5/13/2009 United States
Primary
Concomitant
Vision Blurred 11/1/2008 Male 5/18/2009 Consumer
Primary
Concomitant
Rectal Haemorrhage 1/1/2009 69 Male 310 lb 5/19/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 66 Female 5/13/2009 Lawyer United States
Primary
Concomitant
Urine Flow Decreased Other Serious 2/1/2009 50 Male 172 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dry Mouth 12/5/2008 Female 5/28/2009 Consumer
Primary
Concomitant
Respiratory Tract Congestion 1/1/2009 74 Female 6/25/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 3/17/2008 56 7/29/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 62 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Hypophagia Hospitalization 8/3/2009 77 Male 170 lb 8/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/3/2009 77 Male 170 lb 8/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 1/1/2007 Male 8/10/2009 Consumer
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 74 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Dysphonia 7/1/2009 Male 8/11/2009 Consumer
Primary
Concomitant
Anaemia Other Serious 5/1/2009 Female 8/11/2009 Physician United States
Primary
Concomitant
Glossodynia 8/2/2009 Female 8/13/2009 Consumer
Primary
Concomitant
Enteritis Hospitalization 8/3/2009 Male 170 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Sleep Disorder Due To General Medical Condition, Insomnia Type 6/1/2009 68 Female 8/19/2009 Consumer
Primary
Concomitant
Dyspnoea Female 8/20/2009 Other Health Professional
Primary
Concomitant
Dyspnoea 7/23/2009 Female 8/20/2009 Consumer
Primary
Concomitant
Tremor Hospitalization 6/1/2008 77 Male 8/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Glossodynia 8/2/2009 Female 8/20/2009 Consumer
Primary
Concomitant
Dyspnoea 8/16/2009 Male 8/21/2009 Consumer
Primary
Concomitant
Skin Burning Sensation 11/19/2008 Female 8/22/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Congestion 7/1/2009 Male 8/24/2009 Consumer
Primary
Concomitant
Feeling Abnormal Female 8/23/2009 United States
Primary
Concomitant
Pruritus Generalised 7/23/2009 Male 185 lb 8/23/2009 United States
Primary
Concomitant
Dysuria 4/1/2009 Female 8/25/2009 Consumer
Primary
Concomitant
Disability Other Serious Male 192 lb 8/25/2009 Consumer
Primary
Secondary
Concomitant
Surgery Hospitalization 64 Male 8/20/2009 United States
Primary
Concomitant
Dyspnoea 5/2/2009 Female 8/26/2009 Consumer
Primary
Concomitant
Spinal Fracture Hospitalization 1/1/2007 Male 8/27/2009 Consumer
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 8/26/2009 77 Male 170 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphonia 9/1/2008 67 Male 8/31/2009 Consumer
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 74 Male 8/26/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/28/2009 88 Female 9/3/2009 Consumer
Primary
Concomitant
Sensation Of Foreign Body 7/25/2009 Female 9/4/2009 Consumer
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 8/26/2009 Male 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/23/2009 70 Male 165 lb 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Increased Hospitalization 76 Male 9/15/2009 United States
Primary
Concomitant
Somnolence 9/26/2006 Female 9/28/2009 Consumer
Primary
Concomitant
Drug Ineffective Female 9/28/2009 Consumer
Primary
Concomitant
Wheezing Hospitalization 78 Male 9/21/2009 United States
Primary
Concomitant
Wheezing Other Serious 9/15/2009 66 Female 10/2/2009 Consumer United States
Primary
Concomitant
Condition Aggravated 6/1/2009 58 Female 10/2/2009 Consumer
Primary
Concomitant
Urinary Tract Infection Hospitalization 74 Male 9/25/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Pulmonary Congestion 7/1/2009 Male 10/6/2009 Consumer
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2007 Male 10/8/2009 Consumer
Primary
Concomitant
Vomiting Other Serious 7/20/2005 Male 10/12/2009 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization Female 185 lb 10/12/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/28/2009 88 Female 10/14/2009 Consumer
Primary
Concomitant
Somnolence 9/26/2006 Female 10/14/2009 Consumer
Primary
Concomitant
Pulmonary Embolism Other Serious 3/1/2009 Male 194 lb 10/19/2009 Physician United States
Primary
Concomitant
Drug Ineffective 5/1/2009 Male 10/19/2009 Consumer
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 8/6/2009 Male 130 lb 10/21/2009 Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 74 Male 10/18/2009 Lawyer United States
Primary
Concomitant

Drug Data