Metoprolol combined with Ondansetron

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Death 6/1/2005 70 Female 190 lb 1/13/2006 United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 6/22/2004 79 Female 119 lb 4/28/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/23/2006 74 Male 190 lb 11/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 9/4/2007 59 Female 216 lb 10/17/2007 Physician Germany
Primary
Concomitant
Central Line Infection Hospitalization 9/19/2007 55 Male 225 lb 11/12/2007 Other Health Professional United States
Primary
Concomitant
Transfusion Reaction Hospitalization 10/8/2007 65 Female 302 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 9/4/2007 59 Female 216 lb 12/3/2007 Physician Germany
Primary
Concomitant
Respiratory Rate Increased Hospitalization 12/4/2007 66 Female 210 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 4/6/2007 61 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Coldness Disability 3/14/2008 58 Male 165 lb 5/28/2008 Other Health Professional United States
Primary
Concomitant
Pneumonitis Hospitalization 5/19/2008 75 Male 164 lb 6/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 5/19/2008 75 Male 164 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/22/2008 Male 6/13/2008 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/14/2008 43 Female 3/31/2008 Pharmacist United States
Primary
Concomitant
Heart Rate Decreased Life Threatening 4/22/2008 Male 111 lb 4/24/2008 United States
Primary
Concomitant
Pneumonitis Hospitalization 5/19/2008 75 Male 164 lb 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 35 Female 11/20/2008 United States
Primary
Secondary
Vomiting Life Threatening 6/25/2008 Male 110 lb 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 35 Female 183 lb 12/11/2008 United States
Primary
Secondary
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/1/2008 Female 178 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 12/18/2007 Female 153 lb 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome 3/1/2009 55 Female 156 lb 3/30/2009 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 2/17/2009 45 Female 138 lb 2/17/2009 Pharmacist United States
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Other Serious 4/6/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 3/25/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Other Serious 1/29/2009 Male 186 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 5/18/2009 63 Male 181 lb United States
Primary
Concomitant
Anaemia Macrocytic Hospitalization 4/28/2009 49 Female 7/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 6/12/2009 Male 219 lb 8/25/2009 Physician United States
Primary
Concomitant
Pain Other Serious 7/10/2009 Female 8/31/2009 Physician Canada
Primary
Concomitant
Qrs Axis Abnormal Death 6/1/2008 Female 178 lb 9/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 9/3/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Death 3/18/2009 Female 9/23/2009 Pharmacist United States
Primary
Concomitant
Creatinine Renal Clearance Decreased Life Threatening 5/24/2009 50 Male 146 lb 6/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 10/7/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 6/25/2007 69 Female 10/9/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 8/26/2009 53 Male 128 lb 10/2/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 9/27/2009 44 Male 148 lb 10/2/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 9/27/2009 52 Male 201 lb 10/7/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 12/24/2008 89 Female 11/25/2009 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 7/19/2008 81 Male 145 lb 11/20/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Ischaemic Stroke Death 6/1/2008 61 Female 178 lb 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 4/1/2007 Female 226 lb 12/11/2009 Physician Netherlands
Primary
Secondary
Concomitant
Oesophagitis Other Serious 11/9/2009 Female 128 lb 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/10/2009 Female 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Vertigo Other Serious 12/8/2009 94 Female 12/23/2009 Consumer United States
Primary
Concomitant
Oesophagitis Other Serious 11/9/2009 Female 128 lb 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Required Intervention 10/5/2009 82 Female 181 lb 10/7/2009 Pharmacist United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Systemic Candida Other Serious 11/9/2009 Female 128 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/17/2010 59 Male 187 lb 1/22/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2009 Male 1/27/2010 United States
Primary
Concomitant
Generalised Oedema Hospitalization 2/22/2010 Female 3/10/2010 Physician United States
Primary
Concomitant
Vascular Test Abnormal Hospitalization 10/6/2009 89 Female 2/17/2010 Physician United States
Primary
Concomitant
Vascular Test Abnormal Hospitalization 10/6/2009 89 Female 2/17/2010 Physician United States
Primary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 2/1/2002 3/31/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/12/2010 46 Female 124 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/22/2010 66 Male 5/5/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Female 212 lb 5/11/2010 Physician
Primary
Secondary
Concomitant
Vertigo Other Serious 12/8/2009 94 Female 5/17/2010 Consumer United States
Primary
Concomitant
Rash Generalised Other Serious 1/9/2008 39 Female 134 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 80 lb 5/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 6/3/2010 United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2008 51 Male 218 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 2/5/2007 65 Female 231 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased 4/30/2007 56 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant
White Clot Syndrome Other Serious Male 175 lb 6/29/2010 Lawyer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2010 84 Female 141 lb 7/7/2010 Physician Germany
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 2/11/2008 65 Male 7/15/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 7/21/2010 United States
Primary
Concomitant
Skin Laceration 3/28/2010 57 Male 220 lb 5/25/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 11/11/2009 57 Male 249 lb 11/30/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Toxic Neuropathy Hospitalization 7/14/2010 66 Female 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 8/10/2010 United States
Primary
Concomitant
Pancytopenia Life Threatening 8/2/2010 86 Female 133 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 63 Male 140 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/5/2010 54 Female 143 lb 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 5/17/2010 55 Male 147 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Diarrhoea Haemorrhagic Hospitalization 9/3/2010 69 Male 10/5/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 10/14/2010 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/5/2007 39 Female 134 lb 10/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Vomiting 6/1/2010 84 Female 141 lb 11/1/2010 Physician Germany
Primary
Secondary
Concomitant
Ulcer Hospitalization 6/1/2010 32 Male 275 lb 11/4/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 78 Male 11/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 9/29/2010 66 Female 143 lb 11/24/2010 Physician New Zealand
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2010 20 Female 120 lb 11/10/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Vomiting Hospitalization 3/12/2010 46 Female 124 lb 12/16/2010 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 11/6/2009 65 Female 170 lb 12/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/6/2009 65 Female 170 lb 1/12/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue 8/1/2008 70 Female 1/13/2011 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 1/1/2008 51 Male 218 lb 1/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 67 Female 1/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Neoplasm Hospitalization 5/21/2010 64 Female 143 lb 1/24/2011 Physician United States
Primary
Secondary
Concomitant
Interacting
Nasopharyngitis Death 1/22/2008 66 Female 1/24/2011 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Hypersensitivity Other Serious 5/1/2008 59 Male 194 lb 2/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 8/1/2008 70 Female 2/4/2011 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization Female 2/22/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 9/28/2010 70 Male 190 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 42 Female 2/24/2011 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 11/25/2010 85 Female 2/25/2011 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/1/2007 48 Female 159 lb 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/6/2009 65 Female 170 lb 3/10/2011 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Life Threatening 2/9/2011 64 Female 237 lb 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 5/1/2008 59 Male 194 lb 3/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/1/2008 70 Female 3/28/2011 Consumer United States
Primary
Concomitant
Hypovolaemic Shock Death 10/1/2007 75 Male 157 lb 3/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Cervical Spinal Stenosis Hospitalization 2/1/2002 63 Male 140 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Other Serious 1/1/2003 84 Female 80 lb 4/6/2011 United States
Primary
Concomitant
Fatigue Hospitalization 4/2/2011 55 Male 144 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Cough Hospitalization 4/2/2011 55 Male 144 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Intracranial Pressure Increased Death 3/17/2011 76 Female 4/27/2011 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 5/11/2011 80 Female 104 lb 6/14/2011 Physician United States
Primary
Secondary
Concomitant