Metoprolol combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Hospitalization 10/1/2005 Female 1/4/2006 Consumer United States
Primary
Concomitant
Blood Creatinine Increased 12/1/2004 89 1/6/2006 Physician United States
Primary
Concomitant
Blood Creatinine Increased 12/1/2004 89 1/6/2006 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 12/23/2005 56 Male 216 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Required Intervention 11/9/2005 79 Female 1/16/2006 Physician United States
Primary
Concomitant
Renal Failure Death 6/1/2005 70 Female 190 lb 1/13/2006 United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 9/14/2005 54 Male 205 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Hyperhidrosis 9/1/2005 43 Female 2/8/2006 Physician United States
Primary
Concomitant
Transfusion Reaction Other Serious 2/1/2004 57 Male 2/8/2006 Canada
Primary
Secondary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/10/2005 84 Female 148 lb 1/16/2006 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/1/2006 42 Male 3/7/2006 Pharmacist Canada
Primary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2002 63 Male 148 lb 3/22/2006 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 6/3/2005 63 Male 218 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Disorder Other Serious 2/6/2006 56 Male 251 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 45 Male 205 lb 5/12/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 44 Female 5/12/2006 Physician Canada
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Submaxillary Gland Enlargement Life Threatening 1/22/2006 Female 118 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 5/8/2006 83 Female 135 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Rash 5/29/2005 67 Female 7/21/2006 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/14/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/18/2006 Male 9/12/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 8/31/2006 56 Female 207 lb 9/13/2006 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 9/5/2006 54 Female 198 lb 10/2/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/12/2006 59 Male 10/13/2006 Pharmacist United States
Primary
Concomitant
Oesophagitis Other Serious 9/29/2006 Female 56 lb 10/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/24/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 1/13/2007 Male 166 lb 9/15/2007 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 5/31/2007 65 Male 9/27/2007 Other Health Professional Netherlands
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 6/1/2007 Female 219 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 9/8/2007 77 Female 165 lb 10/2/2007 United States
Primary
Concomitant
Wrong Drug Administered Required Intervention 9/3/2007 34 Female 165 lb 9/27/2007 Pharmacist United States
Primary
Concomitant
Urethral Polyp Hospitalization 7/10/2007 60 Female 10/22/2007 Physician United States
Primary
Concomitant
Tinnitus Hospitalization 3/1/2007 83 Male 10/23/2007 Physician Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 7/10/2007 60 Female 11/13/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Death 7/27/2007 Male 130 lb 11/6/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/2/2007 Female 12/5/2007 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 11/14/2007 70 Female 146 lb 12/3/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 12/17/2007 Female 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Drug Level Increased Death 45 Male 1/16/2008 Physician Canada
Primary
Secondary
Urinary Tract Infection Life Threatening 1/1/2007 59 Female 187 lb 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 4/6/2007 61 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Coldness Disability 3/14/2008 58 Male 165 lb 5/28/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 3/5/2008 70 Female 190 lb 6/20/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/15/2008 Male 192 lb 7/22/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 7/28/2008 Male 156 lb 7/31/2008 Pharmacist United States
Primary
Concomitant
Neurotoxicity Hospitalization 12/11/1998 Male 7/23/2008 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Mental Status Changes Required Intervention 6/6/2008 51 Male 205 lb 10/25/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 11/2/2008 12/11/2008 Physician Hungary
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/2/2008 12/12/2008 Physician Hungary
Primary
Secondary
Concomitant
Urine Abnormality Other Serious 10/4/2007 Female 90 lb 12/30/2008 Consumer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 6/21/2006 67 Female 146 lb 12/22/2008 Physician Sweden
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 12/27/2008 1/8/2009 Pharmacist United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/27/2008 1/9/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/28/2008 Female 119 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Peritonitis Bacterial Hospitalization 1/7/2009 60 Female 241 lb 1/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Tachyarrhythmia Life Threatening 10/23/2008 74 Male 181 lb 3/9/2009 Physician Germany
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/27/2008 3/20/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/27/2008 81 Female 4/15/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 42 Male 240 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/7/2009 58 6/1/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 5/29/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Other Serious 1/29/2009 Male 186 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Life Threatening 4/2/2009 Female 105 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/25/2002 43 Male 257 lb 7/27/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/19/2009 70 Male 216 lb 6/10/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/19/2009 70 Male 216 lb 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Ureteric Cancer Death 71 Male 8/4/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2009 Female 8/24/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/19/2009 70 Male 216 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Ovarian Cancer Death 10/10/2008 64 Female 9/10/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Tremor Required Intervention 7/21/2009 65 7/22/2009 United States
Primary
Secondary
Concomitant
Multiple Sclerosis Other Serious 5/1/2007 Male 9/29/2009 Consumer United States
Primary
Secondary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 7/1/2009 Male 260 lb 10/2/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Swelling Other Serious 12/1/2008 Male 275 lb 10/14/2009 Consumer United States
Primary
Concomitant
Back Pain Hospitalization 9/19/2009 73 Female 10/10/2009 Consumer Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/25/2009 52 Male 196 lb 10/21/2009 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 9/23/2009 75 Male 209 lb 9/25/2009 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 4/11/2008 69 Male 10/28/2009 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 9/4/2009 64 Male 11/2/2009 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Other Serious 9/27/2009 52 Male 201 lb 10/7/2009 United States
Primary
Concomitant
Wound Infection Bacterial Other Serious 26 Female 11/12/2009 United Kingdom
Primary
Secondary
Concomitant
Wound Infection Bacterial Other Serious 26 Female 11/12/2009 United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensorimotor Neuropathy Hospitalization 68 Female 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 11/16/2009 67 Female 140 lb 11/25/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/17/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/24/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
Pancreatitis Haemorrhagic Other Serious 1/1/2008 Female 238 lb 12/1/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/4/2004 Male 12/14/2009 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2005 53 Female 11/25/2009 United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2007 Female 180 lb 12/30/2009 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 10/19/2007 75 Female 1/7/2010 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 9/4/2009 64 Male 1/12/2010 Other Health Professional United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious Male 163 lb 1/15/2010 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 Male 1/18/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 1/13/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/18/2009 65 Female 2/12/2010 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 11/10/2009 65 Male 198 lb 12/7/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 Female 178 lb 3/5/2010 Other Health Professional United States
Primary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 Female 3/10/2010 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization Female 191 lb 3/15/2010 United States
Primary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2000 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 3/29/2010 Consumer United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 9/1/2009 77 Female 4/8/2010 Consumer Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 75 Female 4/13/2010 United States
Primary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/8/2002 60 Female 120 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/31/2010 55 Male 5/5/2010 Pharmacist Canada
Primary
Concomitant
Vomiting Hospitalization 2/23/2010 57 Female 278 lb 2/25/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/8/2002 60 Female 120 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Female 176 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/29/2007 49 Male 287 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2007 68 Male 159 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 6/11/2010 Lawyer United States
Primary
Concomitant
Coagulation Time Prolonged 78 Male 130 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Coagulation Time Prolonged 7/9/2008 60 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant

Drug Data