Metoprolol combined with Mirtazapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Sleep Disorder Hospitalization 1/1/2000 64 Male 227 lb 1/20/2006 Physician United States
Primary
Concomitant
Sleep Disorder Hospitalization 1/1/2000 64 Male 227 lb 2/27/2006 Physician United States
Primary
Concomitant
Muscle Rigidity Hospitalization 12/11/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Dystonia 2/20/2006 54 Male 3/14/2006 United Kingdom
Primary
Concomitant
Spinal Disorder Hospitalization 4/1/2002 51 Male 220 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Nausea Disability 10/10/2005 40 Male 240 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Spinal Disorder Hospitalization 4/1/2002 51 Male 220 lb 5/2/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/30/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 5/3/2006 56 Male 220 lb 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Social Problem Other Serious 9/11/2006 75 Male 170 lb 11/28/2006 Physician Germany
Primary
Secondary
Concomitant
Somnolence 1/1/2007 70 Male 165 lb 10/5/2007 Consumer United States
Primary
Concomitant
Hospitalisation Hospitalization 5/1/2007 75 Female 10/26/2007 Consumer Sweden
Primary
Concomitant
Mental Impairment Other Serious 8/1/2007 Female 10/23/2007 Consumer United States
Primary
Concomitant
Paraesthesia Oral Other Serious 10/26/2006 53 Female 103 lb 11/17/2007 Physician Canada
Primary
Concomitant
Nausea Hospitalization 10/1/2007 Female 12/7/2007 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization Male 1/14/2008 Other Health Professional Australia
Primary
Concomitant
Dyspnoea Exertional Hospitalization 6/6/2008 Female 148 lb 7/15/2008 Germany
Primary
Concomitant
Subdural Hygroma Hospitalization 7/31/2008 Male 118 lb 9/11/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred 4/1/2006 79 Male 12/1/2008 Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/4/2007 Male 181 lb 1/23/2009 United States
Primary
Secondary
Concomitant
Incorrect Route Of Drug Administration Death 8/1/2005 Male 193 lb 1/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mania Hospitalization 1/1/2008 90 Female 2/20/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Sudden Death Death 3/20/2009 Physician Netherlands
Primary
Concomitant
Oedema Peripheral Hospitalization 1/18/2008 39 Male 176 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 1/15/2009 76 Female 110 lb 3/31/2009 Pharmacist United States
Primary
Concomitant
Dyspnoea Male 4/7/2009 Consumer
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 2/4/2009 89 Male 3/3/2009 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 2/17/2009 45 Female 138 lb 2/17/2009 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Death 3/12/2008 77 Female 115 lb 5/11/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Type 2 Diabetes Mellitus Other Serious 4/1/2002 59 Female 151 lb 5/15/2009 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 64 Female 8/4/2009 Lawyer United States
Primary
Concomitant
Flushing 8/1/2008 Male 8/21/2009 United States
Primary
Concomitant
Arthralgia 9/11/2008 Male 155 lb 8/22/2009 Consumer United States
Primary
Concomitant
Pruritus Female 8/22/2009 United States
Primary
Concomitant
Blood Glucose Increased 7/14/2009 Female 180 lb 8/23/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/1/2007 58 Female 9/3/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 64 Female 10/10/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 6/25/2007 69 Female 10/9/2009 United States
Primary
Concomitant
Drug Abuse Death 10/22/2009 Physician United States
Primary
Secondary
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/28/2009 Female 10/29/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 10/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 10/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 85 Male 134 lb 10/30/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 271 lb 11/2/2009
Primary
Secondary
Concomitant
Speech Disorder Other Serious 1/1/2009 Male 218 lb 11/17/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 7/1/2007 62 Female 11/25/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 71 Female 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2006 75 Male 170 lb 11/30/2009 Physician Germany
Primary
Secondary
Concomitant
Speech Disorder Other Serious 1/1/2009 Male 218 lb 11/30/2009 Consumer United States
Primary
Concomitant
Device Dislocation Hospitalization 8/8/2009 Female 112 lb 12/9/2009
Primary
Concomitant
Device Dislocation Hospitalization 8/8/2009 Female 112 lb 12/15/2009
Primary
Concomitant
Speech Disorder Other Serious 1/1/2009 Male 218 lb 12/16/2009 Consumer United States
Primary
Concomitant
Oncologic Complication Death 1/1/2008 Female 1/7/2010 Other Health Professional United States
Primary
Concomitant
Status Epilepticus Hospitalization Male 172 lb 12/30/2009 Other Health Professional Germany
Primary
Concomitant
Renal Failure Hospitalization 9/11/2009 67 Male 227 lb 1/14/2010 Germany
Primary
Concomitant
Weight Decreased Death 1/1/2008 Male 1/14/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/16/2009 47 Male 276 lb 1/20/2010 Physician Germany
Primary
Concomitant
Speech Disorder Other Serious 1/1/2009 Male 218 lb 1/22/2010 Consumer United States
Primary
Concomitant
Weight Decreased Death 1/1/2008 Male 1/27/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 11/1/2009 47 Male 276 lb 1/28/2010 Physician Germany
Primary
Concomitant
Malignant Neoplasm Progression Death 1/1/2008 Female 95 lb 2/1/2010 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 1/1/2009 Male 214 lb 3/9/2010 Consumer United States
Primary
Concomitant
Speech Disorder Other Serious 1/1/2009 39 Male 218 lb 4/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Death 1/1/2008 72 Male 179 lb 5/6/2010 Other Health Professional United States
Primary
Concomitant
Sinusitis Hospitalization 4/6/2010 78 Female 90 lb 5/20/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2010 88 Female 6/16/2010 United States
Primary
Secondary
Concomitant
Failure To Thrive Other Serious 92 Female 90 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 3/19/2010 89 Female 154 lb 6/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/19/2010 89 Female 154 lb 6/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased 5/1/2008 57 Male 160 lb 7/7/2010 Consumer United States
Primary
Concomitant
Nausea 1/1/2007 54 Female 240 lb 7/12/2010 Consumer United States
Primary
Concomitant
Local Swelling Hospitalization 6/29/2010 61 Female 7/14/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2010 88 Female 291 lb 7/20/2010 United States
Primary
Secondary
Concomitant
Venous Stenosis Other Serious 2/1/2008 39 Female 143 lb 7/20/2010 Lawyer United States
Primary
Concomitant
Scleroderma Hospitalization 6/29/2010 61 Female 7/21/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2010 88 Female 291 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Stent Placement Other Serious Female 8/20/2010 Consumer United States
Primary
Concomitant
Skin Burning Sensation 10/1/2009 66 Male 8/28/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/20/2005 45 Male 9/20/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 8/5/2010 84 Male 121 lb 10/25/2010 Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/1/2007 62 Female 10/25/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2010 88 Female 291 lb 11/4/2010 United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death Male 121 lb 11/8/2010 Physician United States
Primary
Secondary
Concomitant
Hunger Other Serious 44 Female 11/3/2010 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 2/1/2008 39 Female 143 lb 12/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Staphylococcal Infection 11/1/2009 12/19/2010 Consumer United States
Primary
Concomitant
Sudden Cardiac Death Death 8/5/2010 Male 121 lb 12/20/2010 Physician United States
Primary
Secondary
Concomitant
Therapy Regimen Changed Other Serious 77 Female 12/6/2010 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 1/1/2010 66 Female 231 lb 1/13/2011 Consumer Hungary
Primary
Concomitant
Sudden Cardiac Death Death 8/5/2010 Male 121 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Scar Other Serious 2/1/2008 39 Female 143 lb 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Life Threatening 11/1/2009 47 Male 276 lb 2/8/2011 Physician Germany
Primary
Concomitant
Hypovolaemia Other Serious 2/29/2008 39 Female 143 lb 2/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 10/16/2007 60 Male 3/9/2011 Lawyer United States
Primary
Concomitant
Clostridium Test Positive Life Threatening 74 Female 4/27/2011 Pharmacist Canada
Primary
Concomitant
Interacting
Dizziness Other Serious 8/9/2010 72 Female 4/27/2011 Consumer United States
Primary
Secondary
Concomitant
Chromaturia 5/17/2011 87 Female 6/8/2011 Other Health Professional United States
Primary
Concomitant
Disorientation Other Serious 3/26/2011 84 Male 6/9/2011 Other Health Professional Sweden
Primary
Concomitant
Asthenia 7/17/2011 48 Male 225 lb 8/8/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Life Threatening 4/25/2011 82 Female 8/19/2011 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased Hospitalization 5/1/2011 83 Female 181 lb 8/22/2011 Other Health Professional Canada
Primary
Concomitant
Delirium Hospitalization 64 Female 8/30/2011 Other Health Professional Switzerland
Primary
Concomitant
Asthenia 7/17/2011 48 Male 225 lb 9/21/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 8/1/2011 74 Male 9/22/2011 Pharmacist United States
Primary
Concomitant
Dysphagia Other Serious 8/1/2011 84 Male 9/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 7/3/2011 71 Male 115 lb 11/15/2011 Physician United States
Primary
Concomitant
Cholestasis Other Serious 88 Female 1/18/2012 Other Health Professional Grenada
Primary
Concomitant
Intentional Overdose Death 1/1/2006 49 Female 2/22/2012 Other Health Professional United States
Primary
Secondary
Drug Abuse Death 1/1/2006 49 Female 2/22/2012 Physician United States
Primary
Secondary
Urinary Tract Infection Hospitalization 6/25/2007 69 Female 130 lb 5/22/2012 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 1/1/2006 62 Male 273 lb 5/25/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Effect Decreased Hospitalization 79 Female 5/30/2012 Other Health Professional United States
Primary
Secondary
Condition Aggravated Death 77 Female 7/6/2012 Pharmacist Canada
Primary
Concomitant
Joint Injury Hospitalization 7/11/2012 64 Female 8/14/2012 Pharmacist United States
Primary
Concomitant
Nasopharyngitis 75 Female 8/17/2012 Other Health Professional United States
Primary
Concomitant
Rectal Cancer Other Serious 2/2012 Male 125 lb 11/9/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Urosepsis Hospitalization 5/2012 Male 190 lb 8/31/2012 Physician Country Not Specified
Primary
Concomitant
Nausea 8/14/2012 74 Female 10/25/2012 Physician Us
Primary
Concomitant
Death Hospitalization 7/29/2012 64 Female 10/5/2012 Physician Us
Primary
Concomitant
Troponin Increased Other Serious 5/2012 Male 8/30/2012 Physician Nz
Primary
Concomitant
Vaginal Haemorrhage 8/26/2012 93 Female 9/4/2012 Consumer Us
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/2/2011 10/9/2012 Physician De
Primary
Concomitant
Death Other Serious 8/29/2012 75 Female 9/19/2012 Other Health Professional Us
Primary
Concomitant
Headache 2012 46 Female 127 lb 10/11/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombotic Cerebral Infarction Hospitalization 1/2012 Female 176 lb 11/28/2012 Physician Au
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/2012 Male 270 lb 10/25/2012 Consumer Us
Primary
Concomitant
Diarrhoea Other Serious 9/2012 82 Male 165 lb 12/21/2012 Consumer De
Primary
Concomitant
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Death Death 10/18/2012 75 Male 11/3/2012 Pharmacist Nl
Primary
Concomitant
Sepsis Other Serious 11/2/2012 69 Female 3/15/2013 Physician Us
Primary
Concomitant
Subdural Haematoma Life Threatening 4/30/2012 89 Male 12/18/2012 Physician Au
Primary
Concomitant
Hypersomnia 11/14/2012 66 Male 3/8/2013 Pharmacist Us
Primary
Concomitant
Renal Failure Acute Hospitalization 10/15/2011 57 Male 12/11/2012 Pharmacist Us
Primary
Concomitant
Renal Failure Acute Death 10/17/2011 57 Male 12/5/2012 Pharmacist Us
Primary
Concomitant
Mobility Decreased Other Serious 11/14/2012 44 Male 205 lb 12/20/2012 Pharmacist Gb
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/21/2012 Physician Us
Primary
Concomitant
Mobility Decreased Other Serious 11/14/2012 44 Male 205 lb 12/27/2012 Other Health Professional Gb
Primary
Concomitant
Respiratory Arrest Death 2011 59 Male 10/18/2013 Physician Us
Primary
Secondary
Tachycardia Hospitalization 2005 Female 1/18/2013 Physician Us
Primary
Concomitant
Toxicity To Various Agents Death 59 Male 1/19/2013 Physician Us
Primary
Secondary
Skin Ulcer Other Serious 2006 62 Male 273 lb 3/13/2013 Lawyer Us
Primary
Secondary
Concomitant

Drug Data