Metoprolol combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/29/2004 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Death 6/1/2005 70 Female 190 lb 1/13/2006 United States
Primary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Death 82 Male 2/9/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 58 Male 2/21/2006 Physician United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12/14/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 44 Female 168 lb 2/27/2006 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/26/2006 Physician United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Hypoglycaemia Death 82 Male 4/24/2006 Canada
Primary
Secondary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 44 Female 168 lb 5/10/2006 Lawyer United States
Primary
Concomitant
Renal Failure Life Threatening 9/18/2006 69 Male 198 lb 10/23/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/27/2006 Physician Germany
Primary
Concomitant
Platelet Count Decreased Required Intervention 8/23/2007 43 Female 104 lb 10/4/2007 United States
Primary
Concomitant
Transfusion Reaction Hospitalization 10/8/2007 65 Female 302 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 4/15/2008 54 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Myoclonus Other Serious 8/19/2008 34 Male 112 lb 8/21/2008 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 1/1/2008 85 Female 12/22/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Weight Increased Death 12/5/2008 69 Female 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Female 161 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Vulvovaginal Pruritus Other Serious 3/30/2004 47 Female 225 lb 5/18/2009 United States
Primary
Concomitant
Wound Other Serious 4/6/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 3/25/2009 54 Female 143 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 5/29/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 66 Male 8/27/2009 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 8/1/2009 66 Male 190 lb 9/1/2009 Pharmacist Canada
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 42 Male 309 lb 9/4/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/23/2008 Female 214 lb 9/16/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 10/21/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 12/4/2008 Male 10/27/2009 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 8/29/2009 53 Female 115 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Urinary Tract Infection 12/6/2006 Female 134 lb 12/1/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Musculoskeletal Stiffness Disability 55 Female 148 lb 1/29/2010 Consumer United States
Primary
Concomitant
Haemorrhage Intracranial Death 1/1/2010 28 Female 2/2/2010 Consumer Philippines
Primary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/1/2010 39 Female 139 lb 5/4/2010 Pharmacist United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 3/1/2009 72 Female 176 lb 5/6/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2003 46 Male 178 lb 5/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 12/27/2008 54 Male 216 lb 5/28/2010 Physician Canada
Primary
Secondary
Concomitant
Yellow Skin Other Serious 5/1/2010 74 Female 168 lb 6/16/2010 Consumer United States
Primary
Secondary
Concomitant
Coagulation Time Prolonged 7/24/2007 69 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/1/2010 39 Female 139 lb 7/16/2010 Pharmacist United States
Primary
Concomitant
Hypotension Other Serious 10/1/2007 56 Male 7/20/2010 Lawyer United States
Primary
Concomitant
Drug Interaction Other Serious 12/30/2009 84 Female 159 lb 7/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/30/2009 84 Female 8/4/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Gastrointestinal Haemorrhage Other Serious 12/1/2009 84 Female 159 lb 8/9/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Interaction Other Serious 12/30/2009 84 Female 159 lb 8/13/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Vomiting Other Serious 1/1/2003 46 Male 178 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 5/17/2010 55 Male 147 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleuritic Pain Other Serious 7/5/2006 36 Female 161 lb 9/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 10/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 79 Female 216 lb 10/13/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 10/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 10/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 11/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 11/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Nephrolithiasis Hospitalization 12/4/2010 63 Female 150 lb 12/29/2010 Other Health Professional United States
Primary
Concomitant
Cholecystitis Other Serious 7/5/2006 36 Female 160 lb 1/14/2011 Consumer United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 7/5/2006 36 Female 160 lb 1/14/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 10/11/2010 80 Male 210 lb 1/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 4/1/2008 31 Female 284 lb 2/3/2011 Lawyer United States
Primary
Concomitant
Electrolyte Imbalance Hospitalization 8/1/2008 70 Female 2/4/2011 Pharmacist United States
Primary
Concomitant
Arrhythmia Death 12/14/2010 57 Male 208 lb 2/10/2011 Consumer United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 3/1/2009 72 Female 176 lb 2/10/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Respiratory Distress Hospitalization 7/28/2010 83 Female 117 lb 2/21/2011 Other Health Professional United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 3/1/2009 72 Female 176 lb 2/22/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Candidiasis Hospitalization Male 2/11/2011 United States
Primary
Concomitant
Sudden Cardiac Death Death 12/14/2010 57 Male 208 lb 3/10/2011 Physician United States
Primary
Concomitant
Bone Lesion Hospitalization 9/23/2003 66 Female 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthma Other Serious 4/1/2008 31 Female 284 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 8/1/2008 70 Female 3/28/2011 Consumer United States
Primary
Concomitant
Hypovolaemic Shock Death 10/1/2007 75 Male 157 lb 3/31/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 12/1/2009 84 Female 159 lb 4/5/2011 Pharmacist Germany
Primary
Concomitant
Interacting
Clostridium Difficile Colitis Other Serious 12/1/2009 84 Female 159 lb 4/5/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Drug Interaction Other Serious 12/1/2009 84 Female 159 lb 4/6/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Cellulitis Staphylococcal Hospitalization 6/1/2006 47 Female 153 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/11/2010 80 Male 210 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 8/8/2011 61 Male 12/2/2011 Pharmacist United States
Primary
Concomitant
Osteoarthritis Other Serious Male 1/1/2012 Physician United States
Primary
Concomitant
Chest Pain Other Serious Male 1/2/2012 Lawyer United States
Primary
Concomitant
Oroantral Fistula Other Serious 1/1/2002 50 Female 198 lb 1/2/2012 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/22/2011 70 Female 94 lb 1/10/2012 Pharmacist United States
Primary
Concomitant
Intestinal Ischaemia Life Threatening 4/23/2012 68 Male 5/22/2012 Physician Netherlands
Primary
Concomitant
Ulcer Haemorrhage Death 4/23/2012 68 Male 5/22/2012 Physician Netherlands
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/25/2007 69 Female 130 lb 5/22/2012 Consumer United States
Primary
Concomitant
Iliac Artery Occlusion Hospitalization 4/23/2012 68 Male 5/24/2012 Physician Netherlands
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/2/2007 78 Female 182 lb 6/7/2012 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 4/23/2012 68 Male 6/12/2012 Physician Netherlands
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 80 Female 157 lb 6/21/2012 Consumer United States
Primary
Concomitant
Malignant Melanoma Death 8/26/2008 78 Male 210 lb 11/16/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Visual Impairment Other Serious Female 11/7/2012 Lawyer Us
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 155 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Tremor Other Serious 9/2008 Female 100 lb 9/17/2012 Lawyer Us
Primary
Concomitant
Road Traffic Accident Death Male 9/12/2012 Physician Us
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 7/2012 52 Female 280 lb 8/28/2012 Us
Primary
Concomitant
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Pulmonary Embolism Hospitalization 5/15/2012 62 Male 12/7/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Rash Hospitalization 12/3/2012 67 Female 287 lb 1/8/2013 Physician Us
Primary
Concomitant
Wound Infection Hospitalization Female 137 lb 12/20/2012 Physician Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/20/2012 Physician Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/21/2012 Physician Us
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 134 lb 1/24/2013 Consumer Country Not Specified
Primary
Concomitant
Wheelchair User Death 2011 84 Female 1/28/2013 Physician Us
Primary
Concomitant
Injection Site Bruising 3/4/2012 51 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Mouth Ulceration Male 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Product Contamination Life Threatening 2/13/2013 54 Female 201 lb 3/12/2013 Pharmacist Us
Primary
Secondary
Concomitant
Pyrexia Other Serious 2012 72 Male 166 lb 5/8/2013 Other Health Professional Us
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 2/13/2013 54 Female 201 lb 3/12/2013 Pharmacist Us
Primary
Secondary
Concomitant
Sepsis Other Serious 2/12/2013 54 Female 3/22/2013 Pharmacist Us
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 3/26/2012 62 Male 225 lb 10/18/2013 Us
Primary
Concomitant
Off Label Use Other Serious 2013 70 Female 4/30/2013 Physician Us
Primary
Concomitant
Transient Ischaemic Attack Death 4/15/2013 85 Male 6/17/2013 Consumer Us
Primary
Concomitant
Glaucoma Other Serious 2013 Female 5/22/2013 Pharmacist Us
Primary
Concomitant
Throat Tightness Hospitalization 1/10/2013 19 Male 7/9/2013 Physician Au
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 4/24/2013 55 Male 238 lb 8/27/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death 77 Female 8/1/2013 Pharmacist Us
Primary
Secondary
Hospice Care 7/25/2013 91 Male 9/10/2013 Consumer Us
Primary
Concomitant
Systemic Candida Death 7/22/2013 68 Male 189 lb 9/23/2013 Consumer Us
Primary
Secondary
Concomitant
Vascular Occlusion Death 9/2003 61 Female 142 lb 8/13/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Death 2002 60 Female 198 lb 12/21/2013 Consumer Us
Primary
Secondary
Concomitant
Vomiting Other Serious 4/20/2010 68 Male 12/18/2013 Consumer Us
Primary
Concomitant

Drug Data