Metolazone combined with Torsemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Life Threatening 12/27/2005 69 Male 200 lb 2/8/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/24/2005 57 Male 3/3/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Scleroderma Death 12/31/2005 60 Male 184 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Milk-alkali Syndrome Hospitalization 80 Female 11/29/2006
Primary
Secondary
Concomitant
Renal Impairment 1/1/2006 58 Female 241 lb 10/16/2006 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 8/16/2006 58 Female 241 lb 4/16/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/12/2007 Female 273 lb 9/5/2007 Pharmacist United States
Primary
Concomitant
Pathological Gambling 7/1/2000 Female 9/25/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 9/9/2007 69 Female 10/25/2007 Physician Switzerland
Primary
Concomitant
Interacting
Pathological Gambling 7/1/2000 Female 10/26/2007 Consumer United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 10/10/2007 Male 175 lb 6/4/2008 United States
Primary
Concomitant
Drug Ineffective 1/1/2001 Male 151 lb 7/25/2008 Consumer United States
Primary
Concomitant
Sickle Cell Anaemia Death Female 135 lb 12/17/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 10/3/2008 72 Male 1/13/2009 Physician Switzerland
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/6/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Life Threatening 6/24/2009 58 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/13/2009 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/14/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 64 Male 250 lb 7/23/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/2/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/18/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 8/25/2009 Female 10/1/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 10/1/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/25/2009 86 Female 10/1/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/22/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Weight Fluctuation Hospitalization 46 Male 10/22/2009 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/12/2008 74 Male 12/9/2008 Pharmacist United States
Primary
Secondary
Paralysis Hospitalization 10/27/2009 84 Male 212 lb 11/9/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 11/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 326 lb 11/16/2009 United States
Primary
Concomitant
Death Death 12/10/2009 Female 139 lb 12/15/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Death 56 Male 12/11/2009 United States
Primary
Concomitant
Pulmonary Hypertension Death Female 139 lb 12/18/2009 Physician United States
Primary
Concomitant
Impaired Self-care Other Serious 6/1/2009 Female 215 lb 12/30/2009 United States
Primary
Concomitant
Ventricular Tachycardia Death 56 Male 189 lb 1/15/2010 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 56 Male 189 lb 2/5/2010 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 56 Male 189 lb 2/5/2010 United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 2/25/2010 Consumer United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 3/5/2010 Lawyer United States
Primary
Secondary
Concomitant
Palpitations Disability 1/18/2010 Female 155 lb 3/19/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 3/26/2010 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Death Death Male 195 lb 4/2/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death Male 195 lb 4/12/2010 Physician United States
Primary
Concomitant
Death Death Female 6/11/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death Female 6/21/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 6/28/2010 Male 239 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/30/2010 Male 8/4/2010 Physician Switzerland
Primary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 9/1/2010 United States
Primary
Concomitant
Pain In Extremity 7/9/2010 64 Male 300 lb 9/16/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence 70 Female 252 lb 9/27/2010 Physician United States
Primary
Concomitant
Gastric Disorder Hospitalization 42 Female 174 lb 10/15/2010 Consumer United States
Primary
Concomitant
Temperature Intolerance Other Serious 63 Male 10/15/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/14/2010 83 Male 168 lb 11/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 8/5/2010 88 Female 11/23/2010 Physician Switzerland
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/16/2008 63 Female 291 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Leukocytosis Hospitalization 46 Male 1/11/2011 Consumer United States
Primary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious 77 Male 275 lb 4/22/2011 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/25/2011 73 Female 5/17/2011 Physician United States
Primary
Concomitant
Pancreatitis Other Serious Female 268 lb 5/19/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 75 Female 179 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7/28/2007 63 Male 218 lb 6/3/2011 Lawyer United States
Primary
Concomitant
Drug Interaction Hospitalization 7/1/2010 67 Male 6/7/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Condition Aggravated Life Threatening 7/1/2010 67 Male 6/7/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 7/1/2010 67 Male 6/7/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Chest Pain Hospitalization 75 Female 179 lb 6/1/2011 Physician United States
Primary
Secondary
Concomitant
Interacting
Lower Gastrointestinal Haemorrhage Hospitalization 6/16/2008 79 Male 6/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Other Serious 7/1/2006 55 Male 351 lb 6/30/2011 Consumer United States
Primary
Concomitant
Nephropathy Hospitalization 7/10/2010 67 Male 7/1/2011 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Incorrect Storage Of Drug Other Serious 5/1/2011 55 Female 7/8/2011 Other Health Professional United States
Primary
Concomitant
Acquired Oesophageal Web Life Threatening 2/15/2011 86 Male 7/15/2011 Pharmacist United States
Primary
Concomitant
Fluid Retention Required Intervention 7/13/2011 76 Female 7/22/2011 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 75 Female 179 lb 8/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphonia Other Serious 1/1/2011 76 Female 8/4/2011 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization 3/1/2011 75 Female 396 lb 8/17/2011 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 8/3/2011 57 Female 193 lb 8/6/2011 Pharmacist United States
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/13/2011 83 Male 9/21/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 8/1/2002 57 Female 150 lb 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 8/18/2011 54 Male 187 lb 10/13/2011 Physician United States
Primary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Haemodialysis Hospitalization 61 Male 10/27/2011 Physician India
Primary
Secondary
Concomitant
Death Death 9/15/2011 74 Female 11/1/2011 Consumer United States
Primary
Concomitant
Blood Urea Increased Hospitalization 61 Male 11/3/2011 Other Health Professional India
Primary
Secondary
Concomitant
Hiatus Hernia Life Threatening 2/15/2011 86 Male 11/3/2011 Pharmacist United States
Primary
Concomitant
Shock Haemorrhagic Hospitalization 69 Male 11/8/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 61 Male 11/14/2011 India
Primary
Secondary
Concomitant
Dyslipidaemia Other Serious 3/1/2000 74 Male 172 lb 11/15/2011 Lawyer United States
Primary
Concomitant
Scrotal Swelling Other Serious 3/1/2000 74 Male 172 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Bursitis Other Serious 3/1/2000 74 Male 172 lb 11/21/2011 Physician United States
Primary
Concomitant
Oesophagogastric Fundoplasty Hospitalization 1/1/2011 11/22/2011 Physician United States
Primary
Concomitant
Visual Acuity Reduced Required Intervention 11/1/2011 48 Female 11/18/2011 Other Health Professional United States
Primary
Concomitant
Hypoacusis Other Serious 3/1/2000 74 Male 172 lb 11/24/2011 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Azotaemia Hospitalization 61 Male 12/2/2011 Other Health Professional India
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 61 Male 12/2/2011 Other Health Professional India
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 61 Male 12/5/2011 Other Health Professional India
Primary
Secondary
Decreased Appetite Other Serious 2/1/2003 77 Male 172 lb 12/8/2011 Physician United States
Primary
Concomitant
Disorientation Hospitalization 2/1/2011 80 Female 134 lb 12/8/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Hospitalization 61 Male 12/12/2011 Other Health Professional India
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 11/17/2011 36 Female 12/12/2011 Physician United States
Primary
Secondary
Concomitant
Bundle Branch Block Left Life Threatening 65 Male 208 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/13/2011 83 Male 12/16/2011 Consumer United States
Primary
Secondary
Concomitant
Pallor Hospitalization 61 Male 12/14/2011 Other Health Professional India
Primary
Secondary
Renal Impairment Hospitalization 61 Male 12/20/2011 Other Health Professional India
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 11/17/2011 36 Female 167 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Azotaemia Other Serious 61 Male 12/20/2011 Other Health Professional India
Primary
Secondary
Concomitant
Delirium Hospitalization 2/1/2011 80 Female 134 lb 12/21/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Hyponatraemia Hospitalization 2/1/2011 80 Female 134 lb 12/21/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Drug Interaction Other Serious 2/1/2011 80 Female 134 lb 12/22/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Acute Prerenal Failure Hospitalization 2/1/2011 80 Female 12/21/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Increased Tendency To Bruise Death 2/1/2003 77 Male 172 lb 1/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious Female 268 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Hypokalaemia Hospitalization 6/17/2004 84 Female 1/12/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Renal Failure Chronic Hospitalization 11/16/2011 90 Female 1/11/2012 Other Health Professional Switzerland
Primary
Secondary
Blood Alkaline Phosphatase Increased Other Serious 12/21/2010 83 Male 11/6/2011 Physician United States
Primary
Concomitant
Cough 11/26/2011 64 Female 1/29/2012 Consumer United States
Primary
Concomitant
Hypoacusis Death 2/1/2003 77 Male 172 lb 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Laceration Other Serious 2/1/2003 77 Male 172 lb 2/8/2012 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 12/24/2011 87 Female 2/23/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/3/2011 65 Female 144 lb 2/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 2/1/2003 77 Male 172 lb 2/29/2012 Physician United States
Primary
Secondary
Concomitant
Asthenia Death Male 157 lb 3/13/2012 Consumer United States
Primary
Concomitant

Drug Data