Metolazone combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Dehiscence Other Serious 1/1/2003 68 Female 280 lb 1/13/2006 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 1/1/2005 76 Male 1/4/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 12/24/2005 57 Male 3/3/2006 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 74 Female 206 lb 3/24/2006 United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 74 Female 206 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Viral Other Serious 6/4/2005 62 Female 197 lb 2/14/2006 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2003 68 Female 280 lb 4/20/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Death 5/21/2006 43 Female 113 lb 5/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Effect Decreased 10/1/2005 63 Male 240 lb 4/3/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2006 76 Female 180 lb 6/14/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2005 81 Male 247 lb 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2005 82 Female 179 lb 2/7/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2005 82 Female 179 lb 2/26/2007 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 8/25/2006 63 Female 165 lb 2/26/2007 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 6/1/2006 42 Female 3/13/2007 Physician United States
Primary
Secondary
Concomitant
Throat Irritation 11/12/2006 45 Female 281 lb 1/23/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2007 57 Female 6/12/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 8/1/2007 United States
Primary
Concomitant
Vascular Occlusion Other Serious 5/1/2007 81 Female 8/3/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 8/6/2007 United States
Primary
Concomitant
Hemianopia Homonymous Other Serious 4/17/2007 Female 9/11/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 7/16/2007 67 Male 118 lb 11/12/2007 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 1/1/2005 74 Male 173 lb 11/13/2007 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 12/17/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2007 57 Female 12/20/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious Female 250 lb 1/8/2008 Pharmacist United States
Primary
Concomitant
Head Injury Hospitalization 12/11/2007 Female 139 lb 2/26/2008 Physician United States
Primary
Concomitant
Head Injury Other Serious 12/10/2007 Female 139 lb 3/21/2008 Physician United States
Primary
Concomitant
Pyrexia Death 3/24/1997 13 Male 97 lb 3/28/2008 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 4/22/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Rhinorrhoea 63 Female 5/1/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2008 50 Female 5/22/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 1/29/2008 99 Female 140 lb 6/17/2008 United States
Primary
Concomitant
Drug Ineffective 1/1/2001 Male 151 lb 7/25/2008 Consumer United States
Primary
Concomitant
Clostridium Difficile Colitis Other Serious 6/27/2008 Female 175 lb 8/4/2008 Physician United States
Primary
Concomitant
Weight Decreased Required Intervention 3/4/2008 98 Female 129 lb 7/30/2008 United States
Primary
Concomitant
Weight Decreased Required Intervention 4/8/2008 98 Female 140 lb 8/20/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 2/15/2008 79 Female 156 lb 10/20/2008 United States
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/15/2008 79 Female 156 lb 11/9/2008 Lawyer United States
Primary
Concomitant
Flushing Hospitalization 1/1/2006 Female 123 lb 1/28/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 329 lb 2/2/2009 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 Female 234 lb 4/24/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/1/2006 Male 295 lb 4/29/2009 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 Female 234 lb 5/28/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 65 Male 6/5/2009 United States
Primary
Concomitant
Death Death 5/29/2009 Female 140 lb 6/26/2009 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization Male 217 lb 6/30/2009 Physician United States
Primary
Concomitant
Death Death Female 119 lb 7/8/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 4/28/2008 65 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Renal Disorder Hospitalization 4/28/2008 65 Male 7/7/2009 United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Female 140 lb 7/23/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Intestinal Haemorrhage Hospitalization Female 260 lb 8/4/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 10/26/2004 75 Male 180 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 8/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Nausea Male 175 lb 8/23/2009 United States
Primary
Concomitant
Weight Increased 1/1/2008 Female 250 lb 8/25/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/2/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Haemorrhage Hospitalization Female 260 lb 9/16/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/18/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/22/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 10/10/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 10/19/2009 United States
Primary
Concomitant
Weight Fluctuation Hospitalization 46 Male 10/22/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/4/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 11/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 326 lb 11/16/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/16/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 11/24/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 77 Female 12/29/2009 Lawyer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 2/1/2009 68 Female 1/5/2010 Physician United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 1/12/2010 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Tachycardia Hospitalization 12/12/2009 Female 2/5/2010 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 12/12/2009 Female 2/9/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 66 Male 2/5/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 2/25/2010 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 2/1/2010 74 Female 3/8/2010 Pharmacist United States
Primary
Concomitant
Asterixis 1/20/2010 61 Female 255 lb 3/10/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 3/5/2010 Lawyer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/1/2009 Female 3/22/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 3/26/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 3/31/2010 United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 3/5/2010 86 Female 159 lb 4/7/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 77 Female 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 2/1/2010 74 Female 4/29/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Other Serious 66 Female 185 lb 5/7/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 37 Male 6/7/2010 United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 12/12/2008 60 Female 234 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 7/26/2010 United States
Primary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 9/1/2010 United States
Primary
Concomitant
Abdominal Discomfort 1/1/2009 78 Female 144 lb 9/20/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence 70 Female 252 lb 9/27/2010 Physician United States
Primary
Concomitant
Blood Test Abnormal Hospitalization Female 129 lb 10/6/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Death 9/21/2010 83 Male 10/20/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening Male 10/26/2010 Consumer United States
Primary
Concomitant
Malaise Female 10/13/2010 Consumer United States
Primary
Concomitant
Abdominal Discomfort 1/1/2009 78 Female 144 lb 11/1/2010 Consumer United States
Primary
Concomitant
No Adverse Event 5/1/2010 68 Female 201 lb 11/8/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening Male 11/11/2010 Physician United States
Primary
Concomitant
Oropharyngeal Pain Death 7/2/2006 12/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Leukocytosis Hospitalization 46 Male 1/11/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 68 Female 2/15/2011 Consumer United States
Primary
Concomitant
Dyslipidaemia Hospitalization 46 Male 326 lb 2/9/2011 Lawyer United States
Primary
Concomitant
Atrial Fibrillation Death 12/1/2009 83 Male 187 lb 2/28/2011 Physician United States
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 1/1/2011 72 Female 220 lb 3/10/2011 Physician United States
Primary
Concomitant
Lung Infection Hospitalization 42 Female 317 lb 4/5/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 59 Female 3/29/2011 Consumer United States
Primary
Concomitant
Disease Progression Hospitalization 68 Female 147 lb 4/20/2011 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 4/1/2011 82 Female 4/29/2011 Pharmacist United States
Primary
Concomitant
Anxiety Death 1/1/2005 2 Female 26 lb 5/7/2011 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious Female 268 lb 5/19/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 12/1/2010 73 Male 242 lb 5/27/2011 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 6/1/2011 93 Male 126 lb 6/13/2011 Physician United States
Primary
Secondary
Concomitant
Head Injury Hospitalization 4/1/2011 82 Female 126 lb 6/16/2011 Pharmacist United States
Primary
Concomitant
Stasis Dermatitis Other Serious 9/1/2005 75 Male 227 lb 7/26/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 12/1/2010 73 Male 242 lb 7/27/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 6/1/2011 93 Male 126 lb 8/11/2011 Physician United States
Primary
Secondary
Concomitant
Ocular Vascular Disorder Other Serious 9/20/2011 10/4/2011 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 10/3/2011 Physician United States
Primary
Concomitant
Carotid Artery Stenosis Other Serious 9/20/2011 10/17/2011 Other Health Professional United States
Primary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/15/2011 11/3/2011 Physician United States
Primary
Concomitant
Hypoaesthesia Hospitalization 1/1/2010 48 Female 128 lb 12/2/2011 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/10/2011 68 Female 144 lb 12/21/2011 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/10/2011 68 Female 144 lb 12/21/2011 Pharmacist United States
Primary
Concomitant
Pancreatitis Other Serious Female 268 lb 11/17/2011 Lawyer United States
Primary
Concomitant

Drug Data