Metolazone combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Hospitalization 1/1/2005 Female 3/27/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/1/2005 Female 112 lb 5/15/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 8/25/2006 63 Female 165 lb 2/26/2007 Physician United States
Primary
Concomitant
Urine Arsenic Increased 1/1/2005 67 Female 9/18/2007 Pharmacist United States
Primary
Secondary
Urine Arsenic Increased 1/1/2005 67 Female 10/15/2007 Pharmacist United States
Primary
Secondary
Respiratory Failure Death Female 1/24/2008 Physician
Primary
Concomitant
Respiratory Failure Death Female 1/30/2008 Physician
Primary
Concomitant
Urine Arsenic Increased 7/1/2007 67 Female 3/7/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2007 Male 265 lb 3/31/2008 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/4/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/11/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 44 Female 5/22/2008 United States
Primary
Concomitant
Dry Mouth Disability 8/5/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Required Intervention 6/17/2008 59 Male 8/27/2008 Physician United States
Primary
Concomitant
Productive Cough 1/1/2006 Male 10/20/2008 Consumer
Primary
Concomitant
Productive Cough 1/1/2006 Male 11/24/2008 Consumer
Primary
Concomitant
Hyponatraemia Hospitalization 10/1/2008 80 Female 11/25/2008 Physician Switzerland
Primary
Secondary
Concomitant
Death Death Male 225 lb 12/23/2008 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death Male 225 lb 1/6/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Required Intervention 6/17/2008 59 Male 2/4/2009 Physician United States
Primary
Concomitant
Respiratory Failure Death Female 158 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/6/2009 Male 222 lb 6/19/2009 Physician United States
Primary
Concomitant
Wheezing Death 3/31/2009 83 Female 6/29/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Life Threatening 6/24/2009 58 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 8/11/2009 United States
Primary
Concomitant
Wheezing Other Serious 3/6/2009 Male 144 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/4/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 9/8/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Sepsis Other Serious 7/1/2009 Male 157 lb 10/2/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 63 Male 180 lb 9/25/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 70 Female 11/18/2009 United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2007 Male 265 lb 12/1/2009 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Swelling Face Required Intervention 9/21/2009 74 Male 218 lb 1/14/2010 Physician United States
Primary
Concomitant
Weight Decreased 64 Female 1/7/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/21/2010 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 73 Female 2/5/2010 Lawyer United States
Primary
Concomitant
Wound Other Serious 73 Female 2/5/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 2/25/2010 Consumer United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 3/26/2010 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea 1/1/2010 66 Male 4/29/2010 Consumer
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 4/7/2010 62 Male 271 lb 5/5/2010 Consumer United States
Primary
Concomitant
Death Death Male 6/30/2010 Consumer United States
Primary
Concomitant
Nasal Congestion 6/13/2010 65 Male 7/1/2010 Consumer
Primary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/9/2010 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 7/9/2010 Consumer United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 7/21/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Liver Disorder Hospitalization Female 198 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Pruritus 6/1/2009 63 Male 360 lb 8/28/2010 Consumer United States
Primary
Concomitant
Ischaemic Cardiomyopathy Death 7/28/2010 64 Male 205 lb 8/30/2010 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization Female 8/30/2010 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Death 9/5/2010 49 Female 9/17/2010 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization Female 9/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 9/23/2010 United States
Primary
Concomitant
Hyperkalaemia Hospitalization Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/31/2010 65 Male 10/7/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death 9/21/2010 83 Male 10/20/2010 Consumer United States
Primary
Concomitant
Fluid Overload Hospitalization 8/16/2010 71 Male 10/22/2010 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization Female 11/11/2010 Physician United States
Primary
Concomitant
Transaminases Increased Hospitalization Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 74 Female 11/11/2010 United States
Primary
Concomitant
Malaise Hospitalization Female 12/3/2010 Physician United States
Primary
Concomitant
Malaise Hospitalization Female 11/30/2010 Physician United States
Primary
Concomitant
Constipation 11/1/2010 90 Male 200 lb 12/8/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2010 90 Male 200 lb 12/21/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious Female 1/4/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 12/10/2010 1/19/2011 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization Female 1/17/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 41 Female 201 lb 1/28/2011 Consumer United States
Primary
Concomitant
Fluid Overload Hospitalization Female 1/17/2011 United States
Primary
Concomitant
Dyspnoea Hospitalization Female 2/4/2011 Physician United States
Primary
Concomitant
Pneumonia Life Threatening 12/10/2010 3/7/2011 Consumer United States
Primary
Secondary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/9/2011 Consumer United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/16/2011 Consumer United States
Primary
Concomitant
Oedema Death 6/24/2011 52 Male 7/28/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Fibrosis Death Female 198 lb 8/1/2011 Physician United States
Primary
Concomitant
Hilar Lymphadenopathy Other Serious Male 9/21/2011 Physician United States
Primary
Concomitant
Leukopenia Hospitalization Male 10/25/2011 Physician United States
Primary
Concomitant
Erectile Dysfunction 4/10/2010 79 Male 10/28/2011 Consumer United States
Primary
Concomitant
Disease Progression Death Male 11/7/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Death 10/15/2011 77 Female 11/10/2011 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 11/1/2006 67 Male 250 lb 11/18/2011 Lawyer United States
Primary
Concomitant
Depression Hospitalization 56 Male 300 lb 11/23/2011 Lawyer United States
Primary
Concomitant
Nicotine Dependence Other Serious 1/1/2006 48 Female 220 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Bundle Branch Block Left Life Threatening 65 Male 208 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Cough Other Serious 1/6/2012 64 Male 1/13/2012 United States
Primary
Concomitant
Abdominal Pain Hospitalization Male 1/17/2012 Physician United States
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization Male 1/18/2012 Physician United States
Primary
Concomitant
Hypoxia Hospitalization Male 1/25/2012 Lawyer United States
Primary
Concomitant
Incorrect Route Of Drug Administration 1/23/2012 83 Male 1/30/2012 Consumer United States
Primary
Concomitant
Obesity Other Serious Male 1/30/2012 Physician United States
Primary
Concomitant
Cough Other Serious 1/6/2012 64 Male 2/20/2012 Physician United States
Primary
Concomitant
Blood Creatinine Increased Death Female 2/10/2012 Lawyer United States
Primary
Concomitant
Fluid Retention 4/1/2011 58 Male 2/29/2012 Consumer United States
Primary
Concomitant
Asthenia Death Male 157 lb 3/13/2012 Consumer United States
Primary
Concomitant
Erythema Hospitalization Male 3/14/2012 Consumer United States
Primary
Concomitant
Deafness 4/8/2012 87 Male 4/19/2012 Consumer United States
Primary
Secondary
Concomitant
Epistaxis Life Threatening 1/17/2012 87 Female 99 lb 4/18/2012 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization Male 5/10/2012 Lawyer United States
Primary
Concomitant
Fluid Retention Hospitalization 3/29/2012 80 Male 5/17/2012 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/1/2012 63 Male 5/23/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 12/11/2005 77 Male 5/9/2012 Physician Canada
Primary
Concomitant
Blood Potassium Decreased Other Serious 3/1/2012 74 Female 163 lb 6/5/2012 Consumer United States
Primary
Secondary
Concomitant
Tobacco Abuse Death 50 Male 154 lb 6/7/2012 Consumer United States
Primary
Concomitant
Adverse Event Hospitalization 3/1/2012 74 Female 163 lb 6/8/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Calculus Urinary Hospitalization 73 Male 209 lb 6/12/2012 Consumer United States
Primary
Concomitant
Adverse Event Other Serious 3/1/2012 74 Female 163 lb 6/18/2012 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Death 63 Male 275 lb 6/19/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 5/11/2012 70 Male 238 lb 6/11/2012 Consumer
Primary
Concomitant
Headache Other Serious 3/1/2012 74 Female 163 lb 7/3/2012 Consumer United States
Primary
Concomitant
Interacting
Adverse Event Hospitalization 3/1/2012 74 Female 163 lb 7/3/2012 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Female 7/13/2012 Other Health Professional United States
Primary
Concomitant
Constipation Other Serious 3/1/2012 74 Female 163 lb 7/30/2012 Consumer United States
Primary
Secondary
Concomitant
Fear Other Serious Male 7/17/2012 Lawyer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/17/2012 88 Female 6/13/2013 Physician Us
Primary
Secondary
Concomitant
Vision Blurred Death 1/2012 51 Male 11/9/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Sepsis Death 12/25/2010 61 Female 290 lb 10/4/2012 Physician Us
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 11/2010 41 Female 201 lb 5/10/2013 Other Health Professional Us
Primary
Concomitant
Drug Level Below Therapeutic Hospitalization 7/28/2012 56 Male 165 lb 11/4/2012 Physician Ch
Primary
Concomitant
Interacting
Skin Discolouration 7/2012 Female 227 lb 11/9/2012 Consumer Us
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 7/28/2012 56 Male 165 lb 11/9/2012 Physician Ch
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 61 Male 11/20/2012 Us
Primary
Secondary
Concomitant
Rectal Haemorrhage 12/11/2012 68 Male 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Subdural Haematoma Death 3/7/2011 70 Male 210 lb 1/16/2013 Consumer Us
Primary
Concomitant
Myocardial Infarction Hospitalization 1/2013 87 Male 181 lb 4/4/2013 Physician Us
Primary
Concomitant
Tremor Hospitalization 1/2013 69 Male 5/8/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Death Death 4/6/2013 74 Male 5/23/2013 Physician Us
Primary
Concomitant
Catheter Site Haematoma Hospitalization 10/12/2012 67 Male 10/16/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Visual Acuity Reduced 2010 Female 115 lb 9/6/2013 Consumer Us
Primary
Concomitant
Visual Acuity Reduced Disability 5/2/2013 56 Female 11/15/2013 Physician Us
Primary
Concomitant
Dizziness 49 Female 8/23/2013 Consumer Us
Primary
Concomitant
Cardiac Failure Chronic Hospitalization 1/14/2013 61 Male 284 lb 8/30/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Haemorrhagic Anaemia Hospitalization 9/15/2013 73 Female 243 lb 10/10/2013 Pharmacist Us
Primary
Concomitant
Tremor Hospitalization 10/2013 87 Female 11/11/2013 Physician Ch
Primary
Concomitant
Pruritus Male 202 lb 11/27/2013 Pharmacist Us
Primary
Concomitant
Oedema Male 12/4/2013 Pharmacist Us
Primary
Concomitant
Fluid Retention Male 237 lb 12/6/2013 Pharmacist Us
Primary
Concomitant
Anaemia Female 198 lb 12/6/2013 Pharmacist Us
Primary
Concomitant
Cardiac Failure Death 10/12/2013 74 Male 12/13/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data