Metolazone combined with Prednisone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/13/2003 48 Male 1/17/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Diarrhoea 7/16/2006 43 Female 135 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Vascular Occlusion Other Serious 5/1/2007 81 Female 8/3/2007 United States
Primary
Concomitant
Spinal Fracture Other Serious 7/23/2007 54 Female 8/9/2007 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/21/2007 Male 178 lb 10/8/2007 United States
Primary
Concomitant
Spinal Fracture Other Serious 7/23/2007 54 Female 10/9/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 10/9/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 9/21/2007 Male 178 lb 10/17/2007 United States
Primary
Concomitant
Pleural Effusion Hospitalization 9/21/2007 Male 178 lb 11/2/2007 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 9/21/2007 Male 178 lb 12/21/2007 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 7/16/2006 44 Female 135 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 Male 4/4/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2008 70 Male 176 lb 7/11/2008 Physician United States
Primary
Concomitant
Clostridium Difficile Colitis Other Serious 6/27/2008 Female 175 lb 8/4/2008 Physician United States
Primary
Concomitant
Factor Viii Inhibition Life Threatening 6/1/2004 Male 265 lb 1/21/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization Female 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 236 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 326 lb 3/24/2009 Other Health Professional United States
Primary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 4/7/2009 United States
Primary
Concomitant
Skin Tightness Other Serious 11/1/2005 59 Female 174 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 11/1/2005 59 Female 174 lb 4/20/2009 Physician United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 6/2/2003 44 Male 401 lb 4/22/2009 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2009 Male 5/19/2009 Consumer United States
Primary
Concomitant
Hypertension Other Serious Male 210 lb 5/22/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/16/2008 59 Female 232 lb 6/5/2009 United States
Primary
Concomitant
Skin Tightness Other Serious 11/1/2005 59 Female 174 lb 6/11/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2009 Male 6/24/2009 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2008 70 Male 176 lb 7/2/2009 Physician United States
Primary
Concomitant
Death Death 7/16/2009 Male 312 lb 8/6/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Wheezing Other Serious 3/6/2009 Male 144 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Death Female 8/20/2009 United States
Primary
Concomitant
Renal Failure Death Male 312 lb 8/31/2009 Physician United States
Primary
Concomitant
Cardioactive Drug Level Increased Hospitalization 3/2/2009 83 Female 159 lb 9/3/2009 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/4/2009 United States
Primary
Concomitant
Septic Shock Other Serious 7/16/2009 55 Male 223 lb 9/16/2009 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Required Intervention 7/2/2009 46 Female 149 lb 7/7/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 9/21/2009 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 63 Male 180 lb 9/25/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Pneumonia Hospitalization Female 10/18/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 8/1/2009 Female 11/5/2009 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 64 Male 11/9/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Social Problem Hospitalization Female 11/3/2009 Lawyer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 11/18/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Weight Increased Other Serious 9/14/2009 Female 114 lb 11/17/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 11/30/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 72 Female 12/2/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 72 Female 12/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 64 Female 1/21/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Tenderness Hospitalization 28 Male 2/5/2010 Lawyer United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2008 77 Male 282 lb 2/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness 11/1/2005 59 Female 174 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Asterixis 1/20/2010 61 Female 255 lb 3/10/2010 Pharmacist United States
Primary
Concomitant
Tenodesis Hospitalization 64 Female 3/5/2010 Lawyer United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Respiratory Failure Death Male 195 lb 4/12/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 4/15/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 192 lb 4/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Male 223 lb 5/11/2010 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 10/1/2007 63 Male 193 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Death Death Female 6/11/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 28 Male 6/11/2010 Lawyer United States
Primary
Concomitant
Respiratory Failure Death Female 6/21/2010 Physician United States
Primary
Concomitant
Death Death Male 6/30/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/8/2010 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/18/2006 63 Female 210 lb 7/8/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/9/2010 Physician United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 6/28/2010 Male 239 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Product Substitution Issue Required Intervention 6/14/2010 53 Female 250 lb 7/12/2010 United States
Primary
Concomitant
Somnolence Other Serious 7/15/2010 56 Female 8/17/2010 Consumer United States
Primary
Concomitant
Respiratory Disorder Hospitalization Female 130 lb 8/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Sepsis Hospitalization Female 130 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 8/30/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 9/1/2010 United States
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 6/14/2010 53 Female 250 lb 8/27/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 9/10/2010 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 9/5/2010 49 Female 9/17/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 34 Female 9/16/2010 United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization Female 9/23/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 9/23/2010 79 Male 205 lb 10/5/2010 Other Health Professional United States
Primary
Concomitant
Blood Test Abnormal Hospitalization Female 129 lb 10/6/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2008 50 Male 10/11/2010 Lawyer United States
Primary
Concomitant
Presyncope Hospitalization Female 160 lb 10/28/2010 Consumer United States
Primary
Concomitant
Sepsis Hospitalization Female 11/16/2010 Consumer United States
Primary
Concomitant
Death Death 5/11/2007 12/6/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 155 lb 12/8/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization Female 12/14/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious Female 1/4/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2007 63 Male 192 lb 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization Female 1/17/2011 Consumer United States
Primary
Concomitant
Fatigue 9/9/2010 62 Female 1/30/2011 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 10/1/2010 47 Female 308 lb 1/30/2011 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 1/1/2011 2/10/2011 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 2/11/2009 67 Male 2/16/2011 Physician Israel
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 7/12/1999 63 Female 2/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 2/11/2009 67 Male 2/28/2011 Consumer Israel
Primary
Secondary
Concomitant
Gout Hospitalization 1/19/2011 51 Male 276 lb 2/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 2/11/2009 67 Male 3/15/2011 Consumer Israel
Primary
Secondary
Concomitant
Nausea Hospitalization 7/12/1999 63 Female 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Disability 11/21/2010 61 Female 184 lb 3/17/2011 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/11/2009 67 Male 3/22/2011 Consumer Israel
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 1/27/2010 61 Male 264 lb 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/4/2001 64 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Death 1/1/2008 77 Male 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Other Serious 59 Female 3/29/2011 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 11/21/2010 61 Female 184 lb 4/15/2011 Physician United States
Primary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Herpes Zoster 3/1/2010 33 Female 157 lb 5/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 68 Male 234 lb 5/10/2011 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 2/11/2009 67 Male 197 lb 5/11/2011 Consumer Israel
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/16/2009 60 Female 155 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/1/2009 60 Female 155 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Brain Injury Death 60 Female 155 lb 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Other Serious Female 291 lb 5/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7/28/2007 63 Male 218 lb 6/3/2011 Lawyer United States
Primary
Concomitant
Haemoglobin Decreased Death 4/7/2011 48 Female 165 lb 5/19/2011 Physician United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/9/2011 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 5/15/2010 80 Female 6/13/2011 Other Health Professional Italy
Primary
Secondary
Concomitant

Drug Data