Metolazone combined with Potassium Chloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Eosinophilia 10/2/2005 68 293 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2004 54 Male 317 lb 1/20/2006 Physician United States
Primary
Secondary
Concomitant
Electromechanical Dissociation Life Threatening 9/12/2005 Male 9/23/2005 United States
Primary
Concomitant
Dysgeusia 10/1/2005 78 Male 200 lb 1/5/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 12/1/2005 65 Male 229 lb 3/20/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/10/2006 Male 135 lb 4/7/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/17/2006 69 Male 177 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Sudden Cardiac Death Death 3/24/2003 63 Male 298 lb 5/11/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/1/2005 Female 112 lb 5/15/2006 Consumer United States
Primary
Concomitant
Hypokalaemia Hospitalization 1/28/2006 80 Male Pharmacist United States
Primary
Secondary
Concomitant
Oedema Hospitalization 1/6/2006 65 Male Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 2/15/2006 66 Female 215 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/14/2006 69 Male 223 lb 4/20/2006 United States
Primary
Concomitant
Hypokalaemia Other Serious 4/21/2006 69 Male 223000 lb 4/24/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 2/15/2006 66 Female 215 lb 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite 1/1/2006 69 Male 177 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Status Epilepticus Life Threatening 5/11/2006 Female 156 lb 8/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious Female 220 lb 9/11/2006 Consumer United States
Primary
Secondary
Concomitant
Nodal Arrhythmia Life Threatening 4/26/2006 Female 205 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Plasmapheresis Hospitalization 9/1/2006 Female 132 lb 10/24/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2002 38 Male 309 lb 10/12/2006 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2004 54 Male 317 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Poor Quality Sleep 5/21/2006 84 Female 9/12/2006 United States
Primary
Concomitant
Plasmapheresis Hospitalization 9/1/2006 Female 132 lb 11/7/2006 Physician United States
Primary
Concomitant
Laryngeal Oedema Life Threatening 8/21/2006 Male 223 lb 10/30/2006 Pharmacist United States
Primary
Concomitant
Tooth Disorder Other Serious Female 220 lb 12/14/2006 Consumer United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/6/2006 58 Male 182 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/29/2006 85 Male 12/29/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 9/29/2006 85 Male 12/29/2006 Physician United States
Primary
Concomitant
Diarrhoea 7/16/2006 43 Female 135 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 1/17/2007
Primary
Secondary
Concomitant
Tooth Disorder Other Serious Female 220 lb 1/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 10/1/2006 78 Female 11/10/2006 Consumer United States
Primary
Concomitant
Syncope Other Serious 62 Male 2/5/2007 Physician United States
Primary
Concomitant
Interacting
Syncope Hospitalization 62 Male 2/6/2007 United States
Primary
Secondary
Vomiting Other Serious 4/1/2006 71 Male 2/16/2007 Physician Singapore
Primary
Concomitant
Drug Toxicity Hospitalization 2/3/2007 53 Male 173 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 2/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 45 Female 134 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Waist Circumference Increased Other Serious 47 Female 162 lb 2/22/2007 Pharmacist United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 1/3/2007 48 Female 2/28/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/2/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/9/2006 66 Male 3/10/2007 Physician Canada
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/6/2007 45 Female 134 lb 3/28/2007 Consumer United States
Primary
Concomitant
Weight Decreased 10/1/2006 48 Male 220 lb 12/11/2006 Consumer United States
Primary
Concomitant
Gait Disturbance 8/1/2005 52 Female 369 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Infection Hospitalization 4/1/2007 65 Female 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Infection Hospitalization 4/1/2007 65 Female 5/4/2007 Consumer United States
Primary
Secondary
Concomitant
Infection Hospitalization 4/1/2007 65 Female 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Tendon Injury Hospitalization 3/12/2007 60 Male 6/19/2007 Consumer United States
Primary
Concomitant
Infection Hospitalization 4/1/2007 65 Female 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 8/1/2007 United States
Primary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 8/6/2007 United States
Primary
Concomitant
Syncope Hospitalization 6/18/2006 74 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 7/26/2007 Male 8/17/2007 Pharmacist United States
Primary
Concomitant
Sinus Congestion Other Serious 5/1/2007 48 Female 381 lb 9/4/2007 Other Health Professional United States
Primary
Concomitant
Bone Pain Other Serious 2/25/2007 60 Female 6/8/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 11/1/2006 67 Male 230 lb 8/24/2007 Consumer United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 62 Male 9/6/2007 United States
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 7/12/2007 Female 273 lb 9/5/2007 Pharmacist United States
Primary
Concomitant
Pathological Gambling 7/1/2000 Female 9/25/2007 Consumer United States
Primary
Concomitant
Fall Hospitalization 6/21/2007 65 Male 121 lb 9/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/21/2007 Male 178 lb 10/8/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 10/9/2007 Consumer United States
Primary
Concomitant
Sinusitis Disability 8/1/2007 66 Female 10/15/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 9/21/2007 Male 178 lb 10/17/2007 United States
Primary
Concomitant
Wheezing Hospitalization 1/1/2004 62 Male 10/16/2007 Physician United States
Primary
Secondary
Weight Increased Hospitalization 1/1/2007 77 Male 10/25/2007 United States
Primary
Secondary
Concomitant
Pathological Gambling 7/1/2000 Female 10/26/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 9/21/2007 Male 178 lb 11/2/2007 United States
Primary
Concomitant
Sinusitis Disability 8/1/2007 66 Female 11/12/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea 81 Male 11/13/2007 Consumer United States
Primary
Concomitant
Weight Increased 9/1/2006 39 Male 11/14/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 11/23/2006 66 Male 230 lb 11/30/2007 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Other Serious 1/1/2005 74 Male 173 lb 11/13/2007 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control 1/1/2005 57 Female 12/15/2007 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 12/17/2007 United States
Primary
Concomitant
Myoclonus Required Intervention 1/29/2006 65 Male 12/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 1/29/2006 65 Male 12/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Speech Disorder Hospitalization 11/1/2007 Male 12/12/2007 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 9/21/2007 Male 178 lb 12/21/2007 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 7/16/2006 44 Female 135 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 58 Female 1/11/2008 Physician United States
Primary
Secondary
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/21/2008 United States
Primary
Concomitant
Respiratory Arrest Death 58 Female 1/21/2008 Physician United States
Primary
Secondary
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/25/2008 United States
Primary
Concomitant
Myoclonus Hospitalization 1/1/2006 65 Male 1/30/2008 Pharmacist United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 2/4/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 58 Female 1/25/2008 Physician United States
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 12/27/2007 81 Female 1/28/2008 Portugal
Primary
Concomitant
Respiratory Arrest Death 58 Female 2/1/2008 Physician United States
Primary
Secondary
Sinusitis Disability 8/1/2007 66 Female 2/11/2008 Other Health Professional United States
Primary
Concomitant
Epistaxis Other Serious 8/1/2005 80 Female 180 lb 11/29/2007 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death 58 Female 2/13/2008 United States
Primary
Secondary
Pleural Effusion Hospitalization 2/4/2008 Male 2/18/2008 United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2006 58 Female 2/13/2008 Physician United States
Primary
Secondary
Vomiting Hospitalization 10/4/2007 44 Female 2/15/2008 Physician United States
Primary
Concomitant
Head Injury Hospitalization 12/11/2007 Female 139 lb 2/26/2008 Physician United States
Primary
Concomitant
Urine Arsenic Increased 7/1/2007 67 Female 3/7/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 44 Female 3/5/2008 Physician United States
Primary
Concomitant
Medication Error Other Serious 12/27/2007 81 Female 3/5/2008 Portugal
Primary
Concomitant
Head Injury Other Serious 12/10/2007 Female 139 lb 3/21/2008 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Death 3/26/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 3/26/2008 Physician United States
Primary
Secondary
Oedema Peripheral 11/13/2007 Male 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2007 Male 265 lb 3/31/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2007 44 Female 3/28/2008 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 Male 4/4/2008 United States
Primary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/4/2008 Other Health Professional United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/11/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization Male 137 lb 4/15/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 4/16/2008
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Male 137 lb 4/21/2008 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/17/2007 Female 295 lb 4/22/2008 United States
Primary
Concomitant
Rhinorrhoea 63 Female 5/1/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2008 5/13/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Respiratory Distress Hospitalization 4/29/2008 Male 260 lb 5/27/2008 Physician United States
Primary
Concomitant
Vomiting Death 3/17/2008 70 Male 5/28/2008 United States
Primary
Concomitant
Cardiac Failure Hospitalization 10/10/2007 Male 175 lb 6/4/2008 United States
Primary
Concomitant
Removal Of Transplanted Organ Other Serious 4/19/2008 45 Female 180 lb 6/9/2008 Physician United States
Primary
Concomitant
Muscular Weakness 4/27/2008 Female 238 lb 6/13/2008 United States
Primary
Concomitant
Hyponatraemia Hospitalization 6/11/2007 65 Male 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 6/13/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/15/2008 61 Female 150 lb 6/9/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/17/2005 66 Male 227 lb 6/20/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 1/29/2008 99 Female 140 lb 6/17/2008 United States
Primary
Concomitant
Removal Of Transplanted Organ Other Serious 4/11/2008 Female 180 lb 7/2/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 12/1/2007 84 Male 150 lb 6/28/2008 United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2008 70 Male 176 lb 7/11/2008 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 7/11/2008 United States
Primary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Weight Decreased Required Intervention 3/4/2008 98 Female 129 lb 7/30/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2008 77 Female 135 lb 8/1/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/13/2004 71 Male 8/14/2008 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2005 69 Female 175 lb 7/7/2008 Consumer United States
Primary
Concomitant
Troponin Increased Hospitalization 1/1/2006 58 Female 8/18/2008 Physician United States
Primary
Secondary
Weight Decreased Required Intervention 4/8/2008 98 Female 140 lb 8/20/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/17/2005 66 Male 227 lb 8/27/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Required Intervention 6/17/2008 59 Male 8/27/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 7/11/2008 Female 170 lb 9/12/2008 Consumer United States
Primary
Concomitant

Drug Data