Metolazone combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sleep Apnoea Syndrome Other Serious 11/8/2000 69 Male 183 lb 1/9/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/7/2006 76 Male 134 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Oedema Hospitalization 1/6/2006 65 Male Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2002 38 Male 309 lb 10/12/2006 Lawyer United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 3/13/2007 Physician United States
Primary
Concomitant
Shock Life Threatening 12/8/2006 Male 317 lb 4/20/2007 Pharmacist United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 4/25/2007 Consumer United States
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/3/2007 69 Female 172 lb 8/7/2007 Consumer United States
Primary
Concomitant
Oedema Hospitalization 9/1/2007 Male 255 lb 9/28/2007 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 2/18/2007 Male 240 lb 4/11/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/27/2007 81 Female 1/28/2008 Portugal
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 9/14/2007 71 Female 2/12/2008 Physician United States
Primary
Concomitant
Medication Error Other Serious 12/27/2007 81 Female 3/5/2008 Portugal
Primary
Concomitant
Oedema Peripheral 11/13/2007 Male 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 3/17/2008 77 Male 175 lb 4/30/2008 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/1/2007 Male 255 lb 7/1/2008 Consumer United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 7/24/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2007 Male 255 lb 7/28/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2008 72 Male 7/29/2008 Consumer United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 8/7/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2008 72 Male 8/14/2008 Consumer United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 9/4/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 53 Female 10/10/2008 United States
Primary
Concomitant
Thrombocytopenia Other Serious 53 Female 10/22/2008 Germany
Primary
Concomitant
Flushing Hospitalization 1/1/2006 Female 123 lb 1/28/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/4/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/26/2008 Male 255 lb 3/5/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/19/2009 Physician United States
Primary
Concomitant
Blood Glucose Increased 10/14/2008 75 Male 234 lb 2/3/2009 Physician United States
Primary
Concomitant
Hypertension Hospitalization 6/2/2003 44 Male 401 lb 4/22/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2009 81 Male 5/12/2009 Physician United States
Primary
Concomitant
Liver Disorder Other Serious Female 111 lb 6/15/2009 Consumer United States
Primary
Concomitant
Vomiting Required Intervention 5/9/2009 82 Male 227 lb 6/9/2009 Pharmacist United States
Primary
Concomitant
Urine Output Decreased 82 Male 227 lb 6/24/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/6/2009 Male 144 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 Female 250 lb 8/25/2009 Physician United States
Primary
Concomitant
Metabolic Acidosis Death 7/28/2009 55 Male 348 lb 9/9/2009 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 7/16/2009 55 Male 223 lb 9/16/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/25/2009 Female 10/1/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 10/1/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/25/2009 86 Female 10/1/2009 Pharmacist Switzerland
Primary
Secondary
Concomitant
Wheezing Hospitalization 4/1/2009 Male 10/28/2009 Physician Canada
Primary
Secondary
Concomitant
Wheezing Hospitalization 4/1/2009 Male 11/10/2009 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2009 58 Female 11/17/2009 Pharmacist United States
Primary
Concomitant
X-ray Limb Abnormal Other Serious 72 Male 11/16/2009 United States
Primary
Concomitant
Weight Increased Other Serious 9/14/2009 Female 114 lb 11/17/2009 United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 12/1/2009 Physician United States
Primary
Concomitant
Peritoneal Cloudy Effluent Other Serious 9/28/2009 83 Male 11/3/2009 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Hospitalization 11/1/2009 Male 12/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Death 5/1/2009 Female 1/5/2010 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 2/1/2009 68 Female 1/5/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 3/1/2009 1 Male 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 60 Male 200 lb 1/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/7/2010 United States
Primary
Concomitant
Cardiac Failure High Output Death 7/14/2009 Female 1/22/2010 Pharmacist United States
Primary
Concomitant
Death Hospitalization 6/1/2009 Female 1/28/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/21/2010 United States
Primary
Concomitant
Ventricular Tachycardia Death 60 Male 200 lb 1/22/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 6/23/2009 Male 300 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Male 980 lb 3/1/2010 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 2/25/2010 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 3/1/2009 1 Male 3/18/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 82 Female 167 lb 3/9/2010 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 12/1/2009 60 Female 3/26/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 1 Male 3/23/2010 Physician Canada
Primary
Secondary
Concomitant
Skin Necrosis Life Threatening 60 Female 132 lb 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 60 Female 4/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Life Threatening 60 Female 132 lb 4/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Onset Of Sleep 10/1/2008 76 Female 5/3/2010 Consumer
Primary
Concomitant
Renal Failure Death 84 Female 5/3/2010 Lawyer United States
Primary
Concomitant
Skin Necrosis Other Serious 60 Female 132 lb 5/3/2010 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/1/2009 69 Male 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization Female 5/10/2010 Consumer United States
Primary
Concomitant
Torsade De Pointes Life Threatening 64 Female 5/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/12/2010 71 Male 5/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Death Death Female 6/11/2010 Consumer United States
Primary
Concomitant
Skin Necrosis Other Serious 4/10/2010 60 Female 132 lb 6/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Life Threatening 4/10/2010 60 Female 132 lb 6/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 11/1/2009 69 Male 6/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weaning Failure Other Serious 4/27/2010 Female 6/9/2010 Pharmacist United States
Primary
Concomitant
Skin Necrosis Life Threatening 4/10/2010 60 Female 132 lb 6/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death Female 6/21/2010 Physician United States
Primary
Concomitant
Rash Other Serious 2/26/2008 87 Male 151 lb 6/23/2010 Other Health Professional United States
Primary
Concomitant
Death Death Male 6/30/2010 Consumer United States
Primary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 60 Female 132 lb 6/21/2010 United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Nasal Congestion 6/13/2010 65 Male 7/1/2010 Consumer
Primary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/9/2010 Physician United States
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 6/28/2010 Male 239 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 1/1/2010 67 Female 294 lb 7/13/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 84 Female 7/16/2010 Lawyer United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/2/2008 59 Male 220 lb 7/31/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 1 Male 8/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Wheezing Other Serious 1 Male 8/26/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pruritus Male 189 lb 8/28/2010 United States
Primary
Concomitant
Wheezing Other Serious 4/1/2009 1 Male 8/31/2010 Physician Canada
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization Female 8/30/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 77 Male 201 lb 8/27/2010 United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 11/13/2009 72 Female 9/2/2010 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 11/1/2009 69 Male 9/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/1/2009 1 Male 9/20/2010 Physician Canada
Primary
Secondary
Concomitant
Urinary Bladder Polyp Other Serious 1/12/2010 71 Male 9/15/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/21/2010 71 Female 317 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Gait Disturbance Hospitalization Female 9/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 9/23/2010 United States
Primary
Concomitant
Hyperkalaemia Hospitalization Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 11/1/2009 69 Male 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization Male 10/27/2010 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization Male 11/15/2010 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization Female 11/11/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 78 Male 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization Female 12/3/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 78 Male 11/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization Female 11/30/2010 Physician United States
Primary
Concomitant
Fatigue 9/9/2010 62 Female 1/30/2011 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 10/1/2010 47 Female 308 lb 1/30/2011 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization Female 2/4/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/3/2011 2/4/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Death 12/1/2009 83 Male 187 lb 2/28/2011 Physician United States
Primary
Concomitant
Hypotension Death 1/1/2008 84 Female 3/7/2011 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 11/1/2010 80 Female 193 lb 3/16/2011 Consumer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 84 Female 3/31/2011 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/15/2008 64 Female 141 lb 4/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Death 3/15/2008 64 Female 141 lb 4/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Death 1/1/2008 77 Male 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Accident Death 3/15/2008 64 Female 141 lb 4/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/6/2010 94 Male 6/30/2010 Physician United States
Primary
Concomitant
Fall Other Serious 77 Male 275 lb 4/22/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 2/1/2009 72 Female 9/2/2010 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 3/15/2011 66 Male 165 lb 5/3/2011 Pharmacist United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/9/2011 Consumer United States
Primary
Concomitant
Fluid Retention Hospitalization 6/1/2011 68 Male 6/16/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 3/21/2011 89 Male 150 lb 6/15/2011 Pharmacist United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/18/2009 69 Male 234 lb 6/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 63 Female 220 lb 6/22/2011 Pharmacist United States
Primary
Concomitant

Drug Data