Metolazone combined with Nitroglycerin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Dehiscence Other Serious 1/1/2003 68 Female 280 lb 1/13/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2003 68 Female 280 lb 4/20/2006 Physician United States
Primary
Concomitant
Fall Hospitalization 2/21/2006 74 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Status Epilepticus Life Threatening 5/11/2006 Female 156 lb 8/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Hospitalization 8/4/2006 75 Male 9/28/2006 Physician Norway
Primary
Secondary
Concomitant
Tremor Hospitalization 8/4/2006 75 Male 10/12/2006 Physician Norway
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/6/2006 58 Male 182 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypertension 7/1/2006 59 Male 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/27/2006 64 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Insulin Resistance Hospitalization 56 Male 7/23/2007 Consumer United States
Primary
Concomitant
Fall Hospitalization 68 Male 8/6/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 6/18/2006 74 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash 3/8/2007 52 Female 190 lb 8/28/2007 Consumer United States
Primary
Secondary
Concomitant
Urine Arsenic Increased 1/1/2005 67 Female 9/18/2007 Pharmacist United States
Primary
Secondary
Rash 81 Male 249 lb 9/20/2007 Consumer United States
Primary
Concomitant
Urine Arsenic Increased 1/1/2005 67 Female 10/15/2007 Pharmacist United States
Primary
Secondary
Urine Arsenic Increased 7/1/2007 67 Female 3/7/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/10/2007 60 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2005 Male 7/1/2008 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 3/18/2008 7/8/2008 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/16/2008 7/23/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/16/2008 11/21/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Decomposition Hospitalization 8/6/2008 Male 280 lb 12/16/2008 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/31/2008 54 Female 247 lb 2/26/2009 United States
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Sputum Discoloured Hospitalization 4/19/2006 67 Male 180 lb 4/22/2009 United States
Primary
Concomitant
Vomiting Other Serious 9/1/2006 Male 295 lb 4/29/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Hypertension Other Serious Male 210 lb 5/22/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Death 71 Male 5/28/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Wheezing Other Serious 3/6/2009 Male 144 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Unevaluable Event Death 71 Male 8/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Wheezing Death 60 Male 9/4/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 9/15/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Wound Infection Death 56 Male 325 lb 9/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 10/9/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 10/27/2009 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 64 Male 11/9/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/4/2009 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 11/16/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/17/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 11/18/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 11/24/2009 United States
Primary
Concomitant
Syncope Death 6/1/2007 Male 11/24/2009 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2005 Male 12/1/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 6/14/2009 69 Male 12/10/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 6/14/2009 69 Male 12/10/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 6/14/2009 69 Male 12/10/2009 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour Death 6/1/2007 74 Male 12/1/2009 United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2009 64 Male 268 lb 12/16/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Ventricular Tachycardia Death 6/1/2007 74 Male 1/13/2010 United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 1/12/2010 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Skin Discolouration Other Serious 6/23/2009 Male 300 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2010 77 Female 221 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 1/1/2010 58 Male 381 lb 2/23/2010 Consumer Canada
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 6/1/2007 74 Male 2/17/2010 United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 74 Male 3/25/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 3/31/2010 Lawyer United States
Primary
Concomitant
Abdominal Distension Hospitalization Female 5/3/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 11/14/2007 51 Male 5/7/2010 Lawyer United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization Female 5/12/2010 Physician United States
Primary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Septic Shock Other Serious 1/12/2008 75 Male 6/28/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 74 Male 7/2/2010 United States
Primary
Concomitant
Erectile Dysfunction Other Serious 1/2/2008 59 Male 220 lb 7/31/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 74 Male 7/26/2010 United States
Primary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Septic Shock Other Serious 1/10/2008 75 Male 181 lb 8/26/2010 Lawyer United States
Primary
Concomitant
Blood Glucose Increased Male 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 70 Male 165 lb 9/23/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 65 Female 9/23/2010 United States
Primary
Concomitant
Renal Failure Acute Other Serious 8/3/2010 78 Male 172 lb 10/8/2010 Consumer United States
Primary
Concomitant
Presyncope Hospitalization Female 160 lb 10/28/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 11/14/2007 51 Male 11/18/2010 Lawyer United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Septic Shock Other Serious 1/10/2008 75 Male 181 lb 12/20/2010 Lawyer United States
Primary
Secondary
Concomitant
Malaise Hospitalization 12/7/2010 62 Female 12/23/2010 Consumer
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Pneumonia Life Threatening Female 1/6/2011 Consumer United States
Primary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Apparent Death Other Serious Female 1/18/2011 Consumer United States
Primary
Concomitant
Fatigue 9/9/2010 62 Female 1/30/2011 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 12/15/2010 62 Female 1/31/2011 Consumer
Primary
Concomitant
Musculoskeletal Pain Other Serious Female 168 lb 2/7/2011 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 68 Female 2/15/2011 Consumer United States
Primary
Concomitant
Limb Injury Other Serious Female 168 lb 2/18/2011 Consumer United States
Primary
Concomitant
Malaise Life Threatening Female 168 lb 2/25/2011 Physician United States
Primary
Concomitant
Haematochezia Other Serious 1/1/2010 81 Male 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/2010 81 Male 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Death 1/6/2009 56 Male 220 lb 3/21/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2007 77 Female 136 lb 3/23/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 1/1/2007 77 Female 136 lb 3/23/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 1/1/2011 82 Male 3/17/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious Female 229 lb 3/29/2011 Consumer United States
Primary
Concomitant
Fear Of Death Other Serious Female 229 lb 3/29/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 59 Female 3/29/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 2/23/2006 77 Female 148 lb 4/13/2011 Other Health Professional United States
Primary
Concomitant
Movement Disorder Hospitalization Female 168 lb 4/6/2011 Physician United States
Primary
Concomitant
Productive Cough Hospitalization Female 168 lb 4/18/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/1/2011 82 Male 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/1/2011 82 Male 4/29/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Injury Other Serious 3/11/2007 54 Female 190 lb 5/3/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 53 Female 229 lb 5/4/2011 Consumer United States
Primary
Concomitant
Anxiety Death 1/1/2005 2 Female 26 lb 5/7/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/20/2011 73 Male 256 lb 5/5/2011 Pharmacist United States
Primary
Concomitant
Pain Other Serious 68 Male 234 lb 5/10/2011 Physician United States
Primary
Concomitant
Death Other Serious 1/1/2005 71 Female 298 lb 5/18/2011 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization 75 Female 179 lb 6/1/2011 Physician United States
Primary
Secondary
Concomitant
Interacting

Drug Data