Metolazone combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Tachycardia Other Serious 11/13/2003 48 Male 1/17/2006 United States
Primary
Concomitant
Dysgeusia 10/1/2005 78 Male 200 lb 1/5/2006 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 74 Female 206 lb 3/24/2006 United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/1/2006 67 Female 5/11/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/14/2006 69 Male 223 lb 4/20/2006 United States
Primary
Concomitant
Hypokalaemia Other Serious 4/21/2006 69 Male 223000 lb 4/24/2006 Pharmacist United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 1/1/2006 72 Male 8/21/2006 Physician United States
Primary
Concomitant
Intestinal Functional Disorder Hospitalization 1/1/2006 72 Male 9/25/2006 Physician United States
Primary
Concomitant
Sneezing Hospitalization 7/12/2007 Female 208 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 3/1/2008 74 Female 180 lb 5/27/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/15/2008 61 Female 150 lb 6/9/2008 United States
Primary
Concomitant
Vomiting Other Serious 12/6/2008 54 Female 12/11/2008 Consumer United States
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Dehydration Hospitalization 12/31/2008 54 Female 247 lb 2/26/2009 United States
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Mood Swings Other Serious 5/1/2009 Male 5/18/2009 Pharmacist United States
Primary
Concomitant
Mood Swings Other Serious 5/1/2009 Male 6/30/2009 Pharmacist United States
Primary
Concomitant
Renal Function Test Abnormal Disability 1/1/2006 Male 7/6/2009 Consumer United States
Primary
Concomitant
Wound Hospitalization 71 Male 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2003 75 8/18/2009 Pharmacist Canada
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 8/18/2009 Lawyer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 7/29/2009 Female 223 lb 8/27/2009 Consumer United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 1/1/2007 Male 9/4/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 9/16/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Wound Hospitalization 71 Male 142 lb 9/23/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 9/21/2009 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Wound Hospitalization 71 Male 142 lb 10/10/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/13/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/1999 Male 10/15/2009 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/26/2009 United States
Primary
Concomitant
Wound Hospitalization 71 Male 142 lb 10/26/2009 United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 11/9/2009 United States
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2009 Female 165 lb 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 11/18/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 11/16/2009 United States
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2009 Female 165 lb 12/1/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 1/12/2010 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 12/26/2009 Male 262 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2009 78 Male 166 lb 4/30/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/1/2007 77 Male 183 lb 5/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/8/2008 61 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Prostate Cancer Other Serious 1/12/2010 71 Male 5/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Arthralgia 1/1/2009 Male 5/26/2010 United States
Primary
Concomitant
Renal Failure Other Serious 12/18/2008 58 Female 183 lb 5/27/2010 Physician United States
Primary
Concomitant
Septic Shock Other Serious 1/12/2008 75 Male 6/28/2010 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/8/2008 61 Male 7/19/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 7/21/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 9/1/2007 77 Male 183 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 8/24/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Septic Shock Other Serious 1/10/2008 75 Male 181 lb 8/26/2010 Lawyer United States
Primary
Concomitant
Dyspnoea 3/1/2010 73 Male 272 lb 10/13/2010 United States
Primary
Concomitant
Weight Increased 84 Male 154 lb 10/13/2010 United States
Primary
Concomitant
Death Death Male 10/18/2010 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 220 lb 10/19/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 10/27/2010 Consumer United States
Primary
Concomitant
Weight Increased 83 Male 10/13/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 11/30/2010 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Pneumonia Life Threatening Female 1/6/2011 Consumer United States
Primary
Concomitant
Apparent Death Other Serious Female 1/18/2011 Consumer United States
Primary
Concomitant
Musculoskeletal Pain Other Serious Female 168 lb 2/7/2011 Consumer United States
Primary
Concomitant
Limb Injury Other Serious Female 168 lb 2/18/2011 Consumer United States
Primary
Concomitant
Malaise Life Threatening Female 168 lb 2/25/2011 Physician United States
Primary
Concomitant
Dysgeusia Other Serious 1/1/2010 67 Male 3/2/2011 Consumer United States
Primary
Concomitant
Anxiety Death 12/1/2006 67 Male 161 lb 4/20/2011 Lawyer United States
Primary
Concomitant
Productive Cough Hospitalization Female 168 lb 4/18/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 45 Female 401 lb 4/26/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 53 Female 229 lb 5/4/2011 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Death 5/31/2011 66 Female 6/3/2011 Pharmacist United States
Primary
Concomitant
Delirium Other Serious Female 11/8/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Humerus Fracture Other Serious 10/14/2011 87 Female 12/19/2011 Consumer United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 12/7/2011 68 1/2/2012 Physician United States
Primary
Secondary
Concomitant
Increased Tendency To Bruise Death 2/1/2003 77 Male 172 lb 1/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 62 Female 1/11/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 62 Female 1/12/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 62 Female 1/23/2012 Physician United States
Primary
Secondary
Constipation Other Serious Male 1/11/2012 Lawyer United States
Primary
Concomitant
Humerus Fracture Other Serious 10/14/2011 87 Female 2/2/2012 Consumer United States
Primary
Secondary
Concomitant
Hypoacusis Death 2/1/2003 77 Male 172 lb 2/2/2012 Physician United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 1/27/2012 71 Male 224 lb 1/30/2012 Other Health Professional United States
Primary
Concomitant
Shock Death 11/22/2011 76 Female 2/6/2012 Physician United States
Primary
Concomitant
Laceration Other Serious 2/1/2003 77 Male 172 lb 2/8/2012 Physician United States
Primary
Secondary
Concomitant
Intracardiac Thrombus Hospitalization 12/24/2007 46 Male 271 lb 2/23/2012 Other Health Professional United States
Primary
Concomitant
Herpes Zoster Other Serious 2/1/2003 77 Male 172 lb 4/16/2012 Lawyer United States
Primary
Secondary
Concomitant
Moaning Other Serious 1/1/2009 85 Female 255 lb 5/11/2012 Lawyer United States
Primary
Concomitant
Erythema Hospitalization Male 142 lb 5/22/2012 United States
Primary
Concomitant
Anaemia Hospitalization 48 Female 172 lb 5/18/2012 Pharmacist United States
Primary
Secondary
Concomitant
Adverse Event Hospitalization 3/1/2012 74 Female 163 lb 6/8/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Disease Progression Hospitalization 11/30/2011 67 Male 253 lb 6/8/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Calculus Urinary Hospitalization 73 Male 209 lb 6/12/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral Death 11/9/2011 97 Male 156 lb 8/14/2012 Physician United States
Primary
Concomitant
Skin Ulcer Death 48 Female 291 lb 5/20/2013 Consumer Us
Primary
Secondary
Concomitant
Yellow Skin Other Serious 2007 68 Male 256 lb 11/11/2013 Physician Us
Primary
Concomitant
Cardiac Arrest Death 11/11/2011 72 Male 265 lb 10/10/2012 Country Not Specified
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/17/2012 88 Female 6/13/2013 Physician Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/25/2012 66 Female 308 lb 10/12/2012 Physician Us
Primary
Concomitant
Vascular Graft Other Serious 8/2004 61 Male 280 lb 9/4/2012 Consumer Us
Primary
Concomitant
Pulmonary Congestion Hospitalization 5/2012 85 Female 9/21/2012 Physician Us
Primary
Concomitant
Head Injury Other Serious 4/2011 Female 9/21/2012 Other Health Professional Us
Primary
Concomitant
Adverse Event Hospitalization 42 Male 136 lb 9/24/2012 Other Health Professional Us
Primary
Concomitant
Urticaria Other Serious 69 Female 212 lb 9/27/2012 Consumer Us
Primary
Secondary
Sepsis Death 12/25/2010 61 Female 290 lb 10/4/2012 Physician Us
Primary
Concomitant
Fluid Retention 9/22/2012 84 Male 275 lb 11/6/2012 Consumer Us
Concomitant
Fluid Overload Hospitalization 9/2012 NotSpecified 1/15/2013 Consumer Us
Primary
Concomitant
Thinking Abnormal Hospitalization Female 11/12/2012 Consumer Country Not Specified
Primary
Concomitant
Pollakiuria Hospitalization 1/6/2012 64 Male 11/26/2012 Consumer Us
Primary
Secondary
Concomitant
Death Death Male 1/29/2013 Consumer Us
Primary
Concomitant
Renal Failure Hospitalization 1/10/2013 73 Female 151 lb 8/6/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/5/2012 77 Female 194 lb 12/17/2012 Pharmacist Us
Primary
Concomitant
Nausea Other Serious 71 Male 1/28/2013 Other Health Professional Se
Primary
Secondary
Upper Limb Fracture 2/2011 Female 275 lb 1/29/2013 Consumer Us
Primary
Concomitant
Subarachnoid Haemorrhage Death 2/8/2011 81 Male 180 lb 9/13/2013 Consumer Us
Primary
Concomitant
Melaena Hospitalization Male 256 lb 6/10/2013 Other Health Professional Us
Primary
Concomitant
Oedema Peripheral Other Serious 64 Male 3/8/2013 Consumer Us
Primary
Concomitant
Gastrointestinal Haemorrhage Death 8/28/2012 76 Male 418 lb 5/10/2013 Consumer Us
Primary
Concomitant
Liver Function Test Abnormal 3/20/2013 46 Female 4/8/2013 Pharmacist Us
Primary
Concomitant
Renal Failure Hospitalization 2/26/2013 73 Female 4/15/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Urinary Tract Infection 69 Male 4/23/2013 Consumer Us
Primary
Concomitant
Wound Dehiscence Hospitalization 69 Male 5/1/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Septic Shock Hospitalization 4/13/2013 58 Female 4/30/2013 Pharmacist Us
Primary
Secondary
Concomitant
Septic Shock Hospitalization 58 Female 5/14/2013 Physician Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Male 220 lb 10/9/2013 Consumer Us
Primary
Concomitant
Torticollis Other Serious Male 386 lb 6/27/2013 Physician Us
Primary
Concomitant
Tremor Male 386 lb 6/27/2013 Physician Us
Primary
Secondary
Concomitant
Hypertension 1980 27 Male 379 lb 7/1/2013 Physician Us
Primary
Concomitant
Renal Failure Acute Hospitalization 6/18/2012 68 Male 180 lb 11/21/2013 Consumer Us
Primary
Concomitant
Malignant Neoplasm Progression Death 3/2011 73 Female 170 lb 4/1/2014 Other Health Professional Us
Primary
Concomitant
Renal Failure Acute Hospitalization 7/11/2013 41 Female 170 lb 7/29/2013 Consumer Country Not Specified
Primary
Concomitant
Renal Failure Chronic Hospitalization 7/19/2009 70 Male 216 lb 8/27/2013 Other Health Professional Us
Primary
Concomitant
Drug Ineffective 60 Male 220 lb 10/4/2013 Physician Us
Primary
Concomitant
Haemorrhagic Anaemia Hospitalization 9/15/2013 73 Female 243 lb 10/10/2013 Pharmacist Us
Primary
Concomitant
Product Physical Issue 9/2012 80 Male 10/15/2013 Country Not Specified
Primary
Concomitant
Blood Glucose Increased 72 Female 291 lb 10/22/2013 Consumer Us
Primary
Concomitant

Drug Data