Metolazone combined with Metoprolol Tartrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Life Threatening 12/27/2005 69 Male 200 lb 2/8/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Status Epilepticus Life Threatening 5/11/2006 Female 156 lb 8/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 61 Male 360 lb 10/8/2007 Consumer United States
Primary
Concomitant
Deafness Disability 10/25/2007 70 Female 234 lb 12/27/2007 Pharmacist United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Hypothyroidism Other Serious 4/1/2008 Male 228 lb 5/19/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 3/15/2007 Male 308 lb 7/25/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2008 77 Female 135 lb 8/1/2008 Physician United States
Primary
Concomitant
Dry Mouth Disability 8/5/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Hypothyroidism Other Serious 4/1/2008 Male 228 lb 8/25/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 Male 256 lb 11/25/2008 Consumer United States
Primary
Concomitant
Neck Pain Other Serious 12/6/2008 54 Female 12/23/2008 Consumer United States
Primary
Concomitant
Toxic Neuropathy Other Serious 12/1/2008 Male 250 lb 1/9/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Male 256 lb 1/20/2009 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 4/1/2008 56 Female 1/15/2009 Consumer United States
Primary
Concomitant
Yellow Skin Other Serious 1/1/2007 Male 256 lb 2/4/2009 Physician United States
Primary
Concomitant
Product Quality Issue Other Serious 8/1/2008 83 Female 2/13/2009 Consumer United States
Primary
Secondary
Concomitant
Toxic Neuropathy Other Serious 12/1/2008 Male 250 lb 2/26/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/25/2009 67 Male 230 lb 2/24/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/1/1999 Female 408 lb 4/15/2009 United States
Primary
Concomitant
Skin Tightness Other Serious 11/1/2005 59 Female 174 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 4/19/2006 67 Male 180 lb 4/22/2009 United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 11/1/2007 71 Female 142 lb 6/19/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 4/6/2009 85 Male 326 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Life Threatening 5/11/2009 Male 203 lb 7/15/2009 Canada
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Wound Hospitalization 71 Male 8/28/2009 United States
Primary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Unevaluable Event Death 71 Male 8/23/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 10/16/2009 United States
Primary
Concomitant
Paralysis Hospitalization 10/27/2009 84 Male 212 lb 11/9/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 64 Male 11/9/2009 United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Impaired Self-care Other Serious 6/1/2009 Female 215 lb 12/30/2009 United States
Primary
Concomitant
Shock Other Serious 12/1/2007 71 Male 322 lb 12/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Female 1/5/2010 Consumer United States
Primary
Concomitant
Foreign Body Sensation In Eyes Female 1/24/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Syncope Hospitalization Female 220 lb 2/19/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2010 77 Female 221 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 2/5/2010 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 2/17/2010 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2008 77 Male 282 lb 2/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Syncope Hospitalization Female 220 lb 3/4/2010 Physician United States
Primary
Concomitant
Skin Tightness 11/1/2005 59 Female 174 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 Male 250 lb 3/17/2010 Physician United States
Primary
Concomitant
Palpitations Disability 1/18/2010 Female 155 lb 3/19/2010 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 82 Female 167 lb 3/9/2010 Lawyer United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 3/31/2010 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 12/26/2009 66 Male 262 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 69 Female 4/6/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2009 78 Male 166 lb 4/12/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Female 259 lb 4/13/2010 Physician United States
Primary
Concomitant
Pain Hospitalization Female 5/10/2010 Consumer United States
Primary
Concomitant
Weight Increased 11/1/2009 61 Male 280 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 59 Male 6/3/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Cardiac Failure Death Female 7/6/2010 Other Health Professional United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 56 Male 250 lb 7/29/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 8/13/2010 Physician United States
Primary
Concomitant
Ischaemic Cardiomyopathy Death 7/28/2010 64 Male 205 lb 8/30/2010 Physician United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/24/2010 65 Male 167 lb 9/3/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 28 Male 198 lb 9/9/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Urinary Bladder Polyp Other Serious 1/12/2010 71 Male 9/15/2010 United States
Primary
Secondary
Concomitant
Death Death Male 9/24/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence 70 Female 252 lb 9/27/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 9/1/2007 77 Male 183 lb 9/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 29 Male 198 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 29 Male 10/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/31/2010 65 Male 10/7/2010 Consumer United States
Primary
Concomitant
Pancytopenia Required Intervention 11/8/2010 75 Male 11/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/10/2008 75 Male 181 lb 12/20/2010 Lawyer United States
Primary
Secondary
Concomitant
Hypoglycaemia Death 9/1/2007 77 Male 183 lb 1/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/3/2011 2/4/2011 Consumer United States
Primary
Concomitant
Pain Other Serious Female 229 lb 3/29/2011 Consumer United States
Primary
Concomitant
Fear Of Death Other Serious Female 229 lb 3/29/2011 Consumer United States
Primary
Concomitant
Movement Disorder Hospitalization Female 168 lb 4/6/2011 Physician United States
Primary
Concomitant
Walking Disability Other Serious 3/1/2007 55 Female 190 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Drop Attacks Death 6/1/2008 28 Male 198 lb 5/20/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Injury Other Serious Female 291 lb 5/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 75 Female 179 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Schizophrenia Death 6/1/2008 28 Male 198 lb 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 6/1/2008 28 Male 198 lb 6/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Myoclonus Other Serious 6/1/2008 29 Male 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Uterine Cancer Other Serious Female 249 lb 6/8/2011 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization 75 Female 179 lb 6/1/2011 Physician United States
Primary
Secondary
Concomitant
Interacting
Myocardial Infarction Hospitalization 6/1/2008 29 Male 6/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2006 53 Female 229 lb 6/27/2011 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 34 Male 6/30/2011 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 42 Female 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 1/1/2011 63 Male 7/13/2011 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious Female 291 lb 7/21/2011 Lawyer United States
Primary
Secondary
Concomitant
Fluid Retention Required Intervention 7/13/2011 76 Female 7/22/2011 Pharmacist United States
Primary
Concomitant
Dysstasia Death 10/1/2002 76 Female 188 lb 8/1/2011 Consumer United States
Primary
Concomitant
Nausea Hospitalization 75 Female 179 lb 8/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Relapsing Other Serious 11/1/2006 56 Male 250 lb 8/3/2011 Consumer United States
Primary
Concomitant
Dysphonia Other Serious 1/1/2011 76 Female 8/4/2011 Pharmacist United States
Primary
Concomitant
Skin Hypopigmentation Other Serious 48 Female 291 lb 8/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious 12/1/2001 53 Female 196 lb 8/16/2011 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization 3/1/2011 75 Female 396 lb 8/17/2011 Physician United States
Primary
Secondary
Concomitant
Viith Nerve Paralysis Other Serious 9/1/2007 77 Male 183 lb 9/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 9/1/2007 77 Male 183 lb 9/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arthralgia Other Serious 4/13/2007 34 Male 350 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 71 Female 9/28/2011 United States
Primary
Secondary
Oedema Other Serious 4/1/2007 61 Male 10/14/2011 United States
Primary
Concomitant
Dyspnoea 3/1/2010 73 Male 272 lb 10/18/2011 United States
Primary
Concomitant
Dizziness Hospitalization 2/28/2011 77 Male 162 lb 10/20/2011 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 48 Female 291 lb 10/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Impairment Other Serious 71 Female 11/2/2011 Consumer United States
Primary
Secondary
Drug Administered To Patient Of Inappropriate Age Hospitalization 5/1/2009 Female 11/6/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/11/2011 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2009 Female 11/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scrotal Swelling Other Serious 3/1/2000 74 Male 172 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Neoplasm Malignant Death 11/11/2011 72 Male 265 lb 11/11/2011 United States
Primary
Secondary
Concomitant
Bursitis Other Serious 3/1/2000 74 Male 172 lb 11/21/2011 Physician United States
Primary
Concomitant
Blood Electrolytes Abnormal Other Serious 71 Female 11/17/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/24/2011 United States
Primary
Secondary
Concomitant
Hypoacusis Other Serious 3/1/2000 74 Male 172 lb 11/24/2011 Physician United States
Primary
Concomitant
Off Label Use Death 11/11/2011 Male 265 lb 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 11/1/2006 67 Male 250 lb 11/18/2011 Lawyer United States
Primary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 11/11/2011 72 Male 225 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2009 Female 12/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 5/1/2009 Female 12/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 2/1/2003 77 Male 172 lb 12/8/2011 Physician United States
Primary
Concomitant
Cardiac Arrest Death 11/11/2011 72 Male 225 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2009 Female 12/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 5/1/2009 Female 12/11/2011 Other Health Professional
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 9/1/2011 62 Male 300 lb 12/16/2011 Consumer United States
Primary
Concomitant
Shock Death 11/22/2011 76 Female 12/16/2011 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 5/1/2009 Female 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 5/1/2009 Female 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 5/1/2009 Female 1/2/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burning Sensation Other Serious Female 1/3/2012 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 11/1/2006 56 Male 250 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 12/21/2010 83 Male 11/6/2011 Physician United States
Primary
Concomitant

Drug Data