Metoclopramide combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Somnolence Hospitalization 25 Female 132 lb 1/26/2006 Other Health Professional India
Primary
Secondary
Concomitant
Somnolence Hospitalization 25 Female 132 lb 1/26/2006 Other Health Professional India
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 12/19/2005 58 Male 106 lb 1/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/28/2006 69 Male 176 lb 3/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 32 Female 132 lb 3/6/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/28/2006 69 Male 176 lb 3/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/20/2006 Spain
Primary
Concomitant
Thrombocytopenia Other Serious 2/13/2006 76 Male 154 lb 3/13/2006 Physician United Kingdom
Primary
Concomitant
Cytolytic Hepatitis Other Serious 2/20/2006 48 Male 3/29/2006 Spain
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 176 lb 4/5/2006 Physician Spain
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 50 Male 176 lb 4/10/2006 Physician Spain
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/28/2006 64 Male 139 lb 9/21/2006 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased 8/23/2006 48 Female 132 lb 10/13/2006 Pharmacist United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/3/2006 64 Male 139 lb 11/16/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 31 Female 11/27/2006 Physician Canada
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Intra-uterine Death Death 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 31 Female 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Septic Shock Life Threatening 11/29/2006 66 Female 12/22/2006 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 9/1/2006 54 Male 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Macular Life Threatening 10/31/2006 49 Female 1/4/2007 Pharmacist United States
Primary
Concomitant
Drug Hypersensitivity Life Threatening 11/7/2006 26 Female 1/24/2007 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 77 Male 161 lb 1/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/26/2007 United Kingdom
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Life Threatening 11/7/2006 26 Female 1/26/2007 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2005 77 Male 161 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 12/11/2006 39 Female 139 lb 4/19/2007 Physician Germany
Primary
Concomitant
Interacting
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Required Intervention 40 Female 161 lb 5/29/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Respiratory Arrest Life Threatening 6/13/2007 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/13/2007 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/19/2007 39 Female 450 lb 9/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 37 Female 143 lb 12/26/2007 Other Health Professional Singapore
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 11/13/2007 41 Male 12/28/2007 Pharmacist Japan
Primary
Concomitant
Intra-uterine Death Other Serious 31 Female 1/18/2008 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 31 Female 1/18/2008 Physician Canada
Primary
Secondary
Concomitant
Intra-uterine Death Other Serious 31 Female 1/21/2008 Physician Canada
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/22/2007 80 Female 194 lb 1/31/2008 Physician Germany
Primary
Concomitant
Multi-organ Failure Hospitalization 8/22/2007 Female 194 lb 2/28/2008 Physician Germany
Primary
Concomitant
Tracheal Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 4/3/2008 Pharmacist United States
Primary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Toxic Shock Syndrome Death 4/21/2008 Male 209 lb 5/8/2008 Physician United Kingdom
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 165 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/7/2008 49 Female 143 lb 6/17/2008 Physician Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 4/14/2008 31 Female 6/25/2008 Physician Poland
Primary
Secondary
Concomitant
Sepsis Death 3/26/2007 66 Male 176 lb 6/27/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/3/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Shock Syndrome Death 4/21/2008 Male 209 lb 8/26/2008 Physician United Kingdom
Primary
Concomitant
Urinoma Other Serious 39 Female 115 lb 9/24/2008
Primary
Secondary
Concomitant
Urinoma Other Serious 39 Female 115 lb 10/3/2008
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 10/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 46 Female 10/28/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 11/7/2006 26 Female 11/19/2008 Japan
Primary
Concomitant
Sinus Tachycardia Life Threatening 11/7/2006 26 Female 11/19/2008 Japan
Primary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 51 Female 141 lb 2/23/2009
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 51 Female 2/27/2009 Physician Israel
Primary
Concomitant
Skin Laceration Other Serious 1/1/2003 40 Female 150 lb 4/14/2009 United States
Primary
Concomitant
Vomiting Other Serious 35 Female 110 lb 4/20/2009
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 6/4/2009 79 Female 143 lb 7/1/2009 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Other Serious 8/18/2003 36 Female 198 lb 7/14/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Diabetic Coma Other Serious 5/6/2007 52 Female 122 lb 9/23/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 10/7/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 3/1/2009 Female 10/8/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/2/2009 Male 357 lb 8/24/2009 Pharmacist United States
Primary
Concomitant
Off Label Use Other Serious 1/1/2009 38 Male 11/30/2009 Physician Mexico
Primary
Concomitant
Rash Other Serious 11/21/2009 Male 190 lb 12/1/2009 Physician Canada
Primary
Secondary
Concomitant
Toxic Shock Syndrome Death 4/24/2008 Male 209 lb 12/1/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 12/22/2009 Pharmacist Spain
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/19/2009 73 Female 12/28/2009 Physician Norway
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 1/8/2010 Other Health Professional United States
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinoma Hospitalization 39 Female 115 lb 2/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 2/26/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/19/2007 70 Female 3/22/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 Male 3/25/2010 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 5/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Death Female 5/21/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/19/2010 73 Male 198 lb 6/1/2010 Pharmacist Ireland
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 39 Male 6/16/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Post Procedural Haematoma Life Threatening 8/18/2009 63 Male 243 lb 6/15/2010 United States
Primary
Concomitant
International Normalised Ratio Increased 6/12/2007 39 Male 220 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 7/13/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Death 7/3/2010 19 Male 110 lb 7/30/2010 Physician Indonesia
Primary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2008 49 Male 324 lb 8/23/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Pneumothorax Other Serious 8/21/2010 62 Male 187 lb 8/26/2010 Physician Australia
Primary
Concomitant
Pneumothorax Life Threatening 8/21/2010 62 Male 187 lb 8/31/2010 Physician Australia
Primary
Concomitant
Thrombosis Other Serious 10/1/2007 75 Male 9/2/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 10/14/2010 United States
Primary
Concomitant
Swelling Other Serious 1/1/2008 48 Male 324 lb 10/15/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 10/27/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2003 47 Male 180 lb 11/8/2010 United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/24/2009 49 Female 237 lb 10/26/2010 Other Health Professional Australia
Primary
Concomitant
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Hydrocephalus Hospitalization 4/13/2010 49 Male 12/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 12/23/2010 United States
Primary
Concomitant
Urticaria Other Serious 12/8/2010 35 Female 128 lb 1/5/2011 Pharmacist Portugal
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/19/2007 70 Female 1/10/2011 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 70 Female 1/12/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 70 Female 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fibrinolysis Life Threatening 71 Male 3/4/2011 Consumer United Kingdom
Primary
Concomitant
Anaphylactic Reaction Life Threatening 2/17/2011 56 Female 108 lb 3/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 71 Male 3/21/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data