Methylprednisolone combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 5/20/2002 56 Female 2/23/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/13/2006 82 Male 240 lb 4/6/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/27/2006 66 Male Pharmacist United States
Primary
Concomitant
Skin Ulcer Other Serious 5/17/2004 Female 101 lb 6/27/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 43 Female 9/11/2006 Pharmacist United States
Primary
Concomitant
Vocal Cord Disorder Other Serious 7/29/2006 Male 9/25/2006 Physician United Kingdom
Primary
Secondary
Electrolyte Depletion Other Serious 10/5/2006 Female 113 lb 11/18/2006 Consumer United States
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 6/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/4/2007 31 Female 139 lb 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 7/6/2007 61 Female 165 lb 9/13/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/30/2007 Male 9/18/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 9/18/2007 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 10/4/2007 66 Female 99 lb 10/29/2007 Physician Portugal
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 10/4/2007 66 Female 99 lb 11/12/2007 Physician Portugal
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 210 lb 11/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 9/27/2004 64 Female 150 lb 12/6/2007 United States
Primary
Secondary
Concomitant
Coma Death 8/28/2007 Female 2/1/2008 Belgium
Primary
Concomitant
Pulmonary Embolism Other Serious 1/3/2008 Female 107 lb 2/8/2008 Physician Belgium
Primary
Concomitant
Renal Failure Acute Death 8/28/2007 Female 2/27/2008 Belgium
Primary
Concomitant
Diarrhoea Hospitalization 2/15/2006 Female 3/7/2008
Primary
Concomitant
Diarrhoea Hospitalization 2/15/2006 Female 3/7/2008
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 3/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Lipodystrophy Acquired Hospitalization 1/8/2008 Male 172 lb 5/2/2008 Physician Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Pco2 Increased Hospitalization 49 Female 5/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 5/5/2008 62 Female 5/23/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Male 6/18/2008 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/10/2008 64 Female 163 lb 4/6/2008 Pharmacist United States
Primary
Secondary
Lipohypertrophy Hospitalization 3/10/2008 Male 172 lb 7/21/2008 Physician Brazil
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 49 Male 8/6/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
International Normalised Ratio Increased Life Threatening 49 Male 150 lb 8/4/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 49 Male 8/11/2008 Other Health Professional Japan
Primary
Concomitant
Interacting
Potentiating Drug Interaction Other Serious 1/1/2008 49 Male 150 lb 10/8/2008 Other Health Professional Japan
Primary
Secondary
Wound Infection Hospitalization 5/1/2007 52 Female 92 lb 11/18/2008 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Other Serious 10/5/2008 Female 276 lb 12/12/2008 Consumer United States
Primary
Concomitant
Rash Generalised 6/2/2008 52 Female 2/4/2009 Pharmacist United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 11/1/2006 Male 269 lb 5/18/2009 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 5/1/2007 52 Female 92 lb 6/2/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 31 Male 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/2/2005 Male 269 lb 6/17/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 2/6/2009 Female 148 lb 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 2/6/2009 Female 148 lb 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 9/18/2009 United States
Primary
Concomitant
Renal Impairment Other Serious 9/2/2005 Male 269 lb 10/2/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 11/17/2009 United States
Primary
Concomitant
Social Avoidant Behaviour Death 6/1/2007 74 Male 12/1/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 50 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Death 6/1/2007 74 Male 1/13/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 50 Male 1/22/2010 United States
Primary
Concomitant
Osteonecrosis Other Serious Female 2/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 6/1/2007 74 Male 2/17/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 50 Male 2/18/2010 United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/9/2008 89 Female 167 lb 3/8/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/17/2007 Male 62 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 3/24/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 4/5/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization Female 125 lb 4/28/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 39 NotSpecified 4/19/2010 Lawyer United States
Primary
Concomitant
Respiratory Distress Other Serious 12/1/2007 24 Male 278 lb 5/24/2010 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/16/2008 15 Female 139 lb 6/29/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2007 74 Male 7/2/2010 United States
Primary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 11/13/2006 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 7/28/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2007 74 Male 7/26/2010 United States
Primary
Concomitant
Osteonecrosis Other Serious 7/16/2008 15 Female 139 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/1/2010 75 Male 179 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 8/30/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/8/2010 30 Female 143 lb 8/31/2010 Physician United Kingdom
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 9/7/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 3/1/2008 78 Female 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 9/24/2010 United States
Primary
Secondary
Concomitant
Palpitations Other Serious 4/14/2010 79 Female 145 lb 10/1/2010 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 10/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 3/1/2008 78 Female 10/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/28/2010 69 Female 110 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 52 Male 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 50 Male 11/11/2010 United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 11/1/2005 56 Female 123 lb 1/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 39 Female 1/10/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Death 83 Female 144 lb 2/22/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 83 Female 144 lb 2/22/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 49 Female 2/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 1/22/2011 63 Male 2/25/2011 Physician Japan
Primary
Secondary
Concomitant
Cholangitis Hospitalization Female 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 46 Female 3/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 4/14/2010 79 Female 145 lb 3/25/2011 Consumer United Kingdom
Primary
Concomitant
Plantar Fasciitis Other Serious 6/27/2001 4/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 6/27/2001 4/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 2/3/2005 45 Female 165 lb 5/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Amnesia Other Serious 6/27/2001 5/4/2011 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/15/2011 76 Male 181 lb 5/19/2011 Pharmacist United States
Primary
Secondary
Tricuspid Valve Incompetence Other Serious 10/14/2003 6/2/2011 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 57 Male 161 lb 5/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Discomfort Other Serious 4/3/2011 45 Female 160 lb 5/24/2011 Pharmacist United States
Primary
Concomitant
Atrophic Vulvovaginitis Other Serious 10/14/2003 6/21/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dysplasia Hospitalization Female 130 lb 6/21/2011 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 11/1/2010 66 Male 143 lb 6/21/2011 United States
Primary
Concomitant
Kidney Rupture Hospitalization 1/1/2009 53 Male 172 lb 6/28/2011 Other Health Professional Japan
Primary
Concomitant
Impaired Healing Other Serious 53 Male 173 lb 6/29/2011 Physician Japan
Primary
Concomitant
Splenic Vein Thrombosis Other Serious 34 Female 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Diverticulum Intestinal Hospitalization 10/14/2003 7/26/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 7/2/2011 55 Female 8/5/2011 Physician Japan
Primary
Concomitant
Amnesia Hospitalization 10/14/2003 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/14/2003 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Respiration Abnormal Other Serious 4/3/2011 45 Female 160 lb 8/25/2011 Consumer United States
Primary
Concomitant
Malaise Hospitalization 7/2/2011 55 Female 9/12/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/6/2010 31 Female 9/14/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 7/6/2010 31 Female 9/16/2011 Physician Japan
Primary
Concomitant
Actinic Keratosis Other Serious 11/1/2005 56 Female 123 lb 9/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 7/2/2011 55 Female 10/3/2011 Physician Japan
Primary
Concomitant
Varices Oesophageal Other Serious 11/21/2006 35 Female 10/4/2011 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/10/2010 63 Female 223 lb 10/7/2011 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/2/2011 55 Female 10/19/2011 Physician Japan
Primary
Concomitant
Death Other Serious Male 10/28/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 11/1/2005 56 Female 123 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 34 Female 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Depression Hospitalization 1/1/2009 48 Female 200 lb 11/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 4/21/2008 66 Female 142 lb 11/7/2011 Lawyer United States
Primary
Concomitant
Hypercoagulation Other Serious 11/1/2005 56 Female 123 lb 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 4/9/2010 54 Male 160 lb 11/18/2011 Lawyer United States
Primary
Concomitant
Kidney Rupture Hospitalization 4/1/2009 53 Male 172 lb 11/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 74 Male 201 lb 12/5/2011 United States
Primary
Concomitant
Cardiomegaly Hospitalization 3/14/2008 66 Male 210 lb 12/7/2011 Lawyer United States
Primary
Concomitant

Drug Data