Methylprednisolone combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/8/2005 74 236 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 7/5/2005 65 Male 2/1/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Pancreas Transplant Rejection Other Serious Unknown 2/10/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious Unknown 2/13/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious Unknown 2/10/2006 Physician United States
Primary
Concomitant
Spleen Disorder Other Serious 2/10/2006 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 24 Female 123 lb 2/21/2006 United States
Primary
Concomitant
Pancreas Transplant Rejection Other Serious 2/24/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 2/24/2006 Physician United States
Primary
Concomitant
Pancreas Transplant Rejection Other Serious 2/24/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 2/24/2006 Physician United States
Primary
Concomitant
Tachypnoea Other Serious 6 Female 31 lb 3/8/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Brain Oedema Life Threatening 2/24/2006 1 Male 13 lb 3/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 24 Female 123 lb 2/21/2006 United States
Primary
Concomitant
Urine Output Decreased Required Intervention 11/15/2005 64 Female 118 lb 1/3/2006 United States
Primary
Concomitant
Pyrexia Required Intervention 12/2/2005 60 Male 161 lb 12/29/2005 United States
Primary
Concomitant
Face Oedema Life Threatening 3/5/2006 22 Female 99 lb 3/6/2006 United States
Primary
Concomitant
Vasospasm Required Intervention 4/17/2006 45 Female 168 lb 6/6/2006 Physician United States
Primary
Concomitant
Vomiting Death 6/20/2006 Male 125 lb 6/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 7/27/2006 Physician United States
Primary
Concomitant
Neutropenia 4/11/2006 71 Female 143 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 1/26/2005 41 Female 132 lb 8/17/2006 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/28/2006 64 Male 139 lb 9/21/2006 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 5/18/2006 45 Male 176 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 52 Female 11/29/2006 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/17/2006 44 Male 179 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 1/26/2005 41 Female 132 lb 12/4/2006 Other Health Professional Canada
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 3/31/2004 68 Female 1/17/2007 Spain
Primary
Concomitant
Respiratory Failure Hospitalization 1/24/2007 30 Male 202 lb 1/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 2/6/2007 Physician United States
Primary
Concomitant
Renal Failure Death 2/17/2004 Male 134 lb 4/19/2007 Physician Italy
Primary
Concomitant
Surgical Procedure Repeated Life Threatening 7/14/2004 53 Male 6/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 6/26/2007 Physician Greece
Primary
Concomitant
Sinus Tachycardia Other Serious 5/22/2007 53 Female 179 lb 6/20/2007 Pharmacist Canada
Primary
Concomitant
Overdose Death 7/8/2007 24 Male 207 lb 7/19/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 7/19/2007 Physician Greece
Primary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/29/2007 69 Male 182 lb 8/27/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/20/2006 68 Female 154 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 75 Male 194 lb 10/4/2007 Physician Greece
Primary
Concomitant
Multi-organ Failure Hospitalization 1/3/2007 58 Female 112 lb 10/9/2007 Pharmacist United States
Primary
Concomitant
Stenotrophomonas Infection Hospitalization 7/15/2006 62 Female 119 lb 10/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2007 8 Male 88 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/12/2007 39 Male 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Other Serious 5/25/2006 Male 134 lb 12/12/2007 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Drug Ineffective 3/29/2007 Male 157 lb 12/19/2007 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 11/6/2007 Female 115 lb 11/15/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/3/2007 58 Female 112 lb 1/22/2008 Pharmacist United States
Primary
Concomitant
Sudden Death Death 1/14/2007 56 Female 156 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Pallor Hospitalization 1/4/2008 Female 189 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
Pallor Hospitalization 1/2/2008 Male 187 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/17/2008 25 Female 149 lb 3/28/2008 Mexico
Primary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 45 Male 4/3/2008 Physician Singapore
Primary
Secondary
Concomitant
Capillary Leak Syndrome Death 11/6/2007 12 Male 4/14/2008 Physician Italy
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 3/17/2008 Female 149 lb 4/15/2008 Mexico
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 3/17/2008 Female 149 lb 4/16/2008 Mexico
Primary
Concomitant
Ureteral Disorder Death 64 Female 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 3/17/2008 Female 150 lb 4/22/2008 Mexico
Primary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Capillary Leak Syndrome Death 11/6/2007 12 Male 4/25/2008 Physician Italy
Primary
Secondary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 12/14/2006 79 Female 4/28/2008 Taiwan, Province Of China
Primary
Concomitant
Thrombocytopenia Other Serious 10/31/2007 80 Male 5/3/2008 United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 11/1/2007 12 Male 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Septic Shock Death 49 Female 99 lb 6/9/2008 Physician Austria
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 11/7/2007 49 Female 267 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 10/20/2007 35 Female 121 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 10/21/2007 44 Male 272 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 5/8/2008 69 Male 157 lb 6/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2003 24 Female 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 48 Female 7/28/2008 Brazil
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/12/2007 39 Male 8/20/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 8/13/2008 69 Female 9/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 1/1/1993 48 Female 11/4/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 10/2/2008 82 Female 12/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Toxic Death 10/2/2008 82 Female 167 lb 12/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2004 Female 35 lb 1/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/28/2008 Female 163 lb 2/4/2009 Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/11/2007 75 Male 194 lb 2/13/2009 Physician Greece
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 2/13/2007 45 5/26/2009 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 23 Female 5/28/2009 United States
Primary
Concomitant
Haematoma Other Serious 11/7/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 1/9/2004 Female 148 lb 6/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/11/2004 Male 170 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/12/2004 Female 125 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 11 Male 6/19/2009 Other Health Professional United States
Primary
Concomitant
Haemoglobinuria Life Threatening 4/17/2009 51 Male 198 lb 6/17/2009 Physician Canada
Primary
Concomitant
Subcutaneous Abscess Hospitalization 11/9/2004 Male 6/25/2009 Consumer Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/9/2004 Male 7/2/2009 Physician Spain
Primary
Secondary
Concomitant
Gastrointestinal Hypermotility Hospitalization 8/22/2008 44 Female 99 lb 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 57 Female 7/9/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 57 Female 7/14/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Gastrointestinal Hypermotility Hospitalization 8/22/2008 44 Female 99 lb 7/15/2009 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 54 7/21/2009 Physician Korea, Republic Of
Primary
Concomitant
Staphylococcal Infection Life Threatening 12/1/2008 17 Female 8/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/8/2004 70 Male 7/29/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/1/2009 70 Female 144 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/1/2008 54 8/21/2009 Physician Korea, Republic Of
Primary
Concomitant
Small Intestine Ulcer Other Serious 5/1/2009 61 Male 8/19/2009 Physician United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 40 Female 9/9/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
White Blood Cell Count Increased Other Serious 16 Female 9/15/2009
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2007 65 Male 207 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/1/2008 54 9/21/2009 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Other Serious 66 Male 207 lb 9/1/2009 Physician Italy
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Pneumonia Other Serious 3/1/2009 Female 10/8/2009 Physician United States
Primary
Concomitant
Enterovesical Fistula Hospitalization 8/23/2009 Female 10/21/2009 Physician United States
Primary
Concomitant
Death Death 16 10/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Acute Myeloid Leukaemia Death 16 Female 82 lb 11/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Other Serious 66 Male 207 lb 11/4/2009 Physician Italy
Primary
Concomitant
Wound Dehiscence Other Serious 8/1/2009 Female 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Pancreatic Necrosis Hospitalization 12/1/2008 63 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/18/2009 Male 11/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/1/2009 Female 12/8/2009 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 11/28/2009 Male 12/30/2009 Physician United States
Primary
Concomitant
Hepatitis Life Threatening 12/21/2009 32 Female 176 lb 1/4/2010 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 57 Male 12/22/2009 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 1/8/2010 Other Health Professional United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 7/11/2007 16 Female 82 lb 1/25/2010 Physician Korea, Republic Of
Primary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 6/14/2009 62 Female 1/29/2010 Consumer United States
Primary
Concomitant

Drug Data