Methylprednisolone combined with Sirolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyelonephritis Hospitalization 8/29/2005 48 Male 225 lb 5/12/2006 Physician Belgium
Primary
Secondary
Fungal Sepsis Death 8/2/2006
Primary
Concomitant
Renal Tubular Atrophy Other Serious 18 Female 10/11/2006 Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 4/18/2005 Female 141 lb 7/2/2007 Physician Italy
Primary
Concomitant
Transplant Rejection Hospitalization 5/26/2005 Male 192 lb 9/24/2007 Physician United Kingdom
Primary
Concomitant
Transplant Rejection Hospitalization 5/26/2005 Male 192 lb 9/26/2007 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2007 46 Female 10/20/2007 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2007 8 Male 88 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Obliterative Bronchiolitis Other Serious 11/21/2007 United States
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 11/20/2007 Male 203 lb 12/6/2007 Physician Argentina
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/12/2007 39 Male 12/6/2007 Physician United States
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 11/20/2007 Male 203 lb 12/14/2007 Physician Argentina
Primary
Concomitant
Thrombocytopenia Hospitalization 11/16/2007 Female 132 lb 1/18/2008 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Hospitalization 11/10/2007 Female 132 lb 1/31/2008 Physician Korea, Republic Of
Primary
Concomitant
Systemic Candida Other Serious 1/1/2004 37 Male 2/22/2008 Japan
Primary
Secondary
Kaposi's Sarcoma Other Serious 65 3/6/2008 Other Health Professional Germany
Primary
Concomitant
Complications Of Transplant Surgery Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant
Complications Of Transplant Surgery Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant
Urinary Fistula Hospitalization 12/20/2007 Male 3/17/2008 Physician Spain
Primary
Concomitant
Systemic Candida Other Serious 1/1/2004 37 Male 3/27/2008 Japan
Primary
Secondary
Pleural Effusion Other Serious 4/18/2005 Female 141 lb 4/22/2008 Physician Italy
Primary
Concomitant
Renal Mass Other Serious 1/1/2003 60 Female 5/1/2008 Other Health Professional Hungary
Primary
Secondary
Vomiting Other Serious Male 5/5/2008 Physician United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 1/1/2004 37 Male 7/25/2008 Japan
Primary
Secondary
Pulmonary Tuberculosis Other Serious 4/28/2004 Female 76 lb 7/30/2008 Physician Argentina
Primary
Concomitant
Systemic Candida Other Serious 1/1/2004 37 Male 8/8/2008 Japan
Primary
Secondary
Urinary Tract Infection Other Serious 9/22/2008 United States
Primary
Secondary
Urinary Tract Infection Other Serious 9/22/2008 United States
Primary
Secondary
Ureteric Cancer Other Serious 12/1/2003 53 Female 9/25/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 10/7/2008 Male 260 lb 10/20/2008 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/2/2009 United States
Primary
Concomitant
Cytomegalovirus Infection Other Serious 48 5/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 48 5/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 48 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 48 6/22/2009 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 6/7/2003 Female 126 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/21/2003 Female 155 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Wound Infection Other Serious 6/12/2003 Male 141 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/3/2003 Male 139 lb 6/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 8/11/2003 Male 146 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 8/20/2003 Male 6/23/2009 Physician Mexico
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 8/8/2003 Female 123 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 11/5/2003 Male 154 lb 6/23/2009 Physician Austria
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/15/2003 Male 151 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/1/2004 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Lymphocele Life Threatening 11/28/2003 Male 160 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Death 4/26/2004 Male 157 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Urosepsis Hospitalization 1/9/2004 Female 148 lb 6/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Lymphocele Hospitalization 12/18/2003 Female 114 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/6/2003 Male 137 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/20/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Lymphocele Other Serious 2/18/2003 Male 203 lb 6/23/2009 Physician Mexico
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/21/2004 Male 187 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Ureteric Obstruction Other Serious 9/1/2004 Female 6/23/2009 Physician Australia
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 3/20/2005 Male 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/16/2004 Male 198 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 2/17/2004 Male 6/23/2009 Physician Austria
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 12/12/2003 Female 6/23/2009 Physician Austria
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 1/16/2006 Female 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/12/2004 Female 125 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 2/23/2004 Male 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/2/2004 Female 190 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 9/1/2006 Male 6/23/2009 Physician Australia
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/20/2003 Male 203 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/18/2004 Female 6/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 48 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Post Herpetic Neuralgia Life Threatening 5/10/2004 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ureteric Fistula Hospitalization 7/6/2004 Male 6/25/2009 Physician Brazil
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 8/11/2003 Male 6/25/2009 Physician Brazil
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 11/5/2003 Male 6/25/2009 Physician Austria
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 11/9/2004 Male 6/25/2009 Consumer Germany
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 9/1/2003 Male 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 48 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 11/13/2003 Female 6/26/2009 Physician Spain
Primary
Concomitant
Ureteric Obstruction Other Serious 9/1/2004 Female 6/24/2009 Physician Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 4/2/2009 39 Female 110 lb 4/28/2009 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/16/2004 49 Male 6/30/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/1/2004 Male 6/30/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Hospitalization 3/16/2003 Male 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 9/21/2004 Male 7/1/2009 United Kingdom
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/9/2004 Male 7/2/2009 Physician Spain
Primary
Secondary
Concomitant
Vulvovaginal Human Papilloma Virus Infection Other Serious 1/1/1994 42 Female 8/28/2009
Primary
Secondary
Concomitant
Purulence Other Serious 28 Female 12/11/2009 Other Health Professional United States
Primary
Secondary
Weight Decreased Hospitalization 40 Female 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 8/11/2003 39 Male 146 lb 6/2/2010 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Cough Other Serious 20 Male 7/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Swelling Face Other Serious 50 Male 7/28/2010 Germany
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious 8/31/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/31/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 41 Female 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Paralytic Other Serious 22 Male 11/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pathogen Resistance Death 52 Male 12/8/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 41 Female 11/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Graft Thrombosis Other Serious 32 Female 172 lb 12/21/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 15 Male 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 50 Male 12/29/2010 Germany
Primary
Concomitant
Interacting
Peripheral Ischaemia Other Serious 11/1/2007 30 Male 1/26/2011 Physician Spain
Primary
Concomitant
Lymphopenia Hospitalization 16 1/28/2011 Physician Israel
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 16 2/1/2011 Other Health Professional Israel
Primary
Secondary
Cryptosporidiosis Infection Hospitalization 16 Female 2/4/2011
Primary
Secondary
Neutropenia Hospitalization 16 2/7/2011 Physician Israel
Primary
Secondary
Concomitant
Cellulitis Hospitalization 16 Female 2/11/2011 Physician Israel
Primary
Concomitant
Kidney Transplant Rejection Other Serious 1/1/2006 26 Female 3/1/2011 Other Health Professional Canada
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 1/1/2008 28 Female 335 lb 3/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Moyamoya Disease Hospitalization 12/1/2005 Female 4/4/2011 Physician Italy
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 12/1/2009 11 Female 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Other Serious 12/1/2005 29 Female 4/6/2011 Other Health Professional Italy
Primary
Secondary
Pathogen Resistance Hospitalization 12/1/2009 11 Female 4/11/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Moyamoya Disease Other Serious 12/1/2005 29 Female 4/29/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/5/2010 69 Male 5/5/2011 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 16 Female 5/18/2011 Other Health Professional Israel
Primary
Secondary
Blood Creatinine Increased Hospitalization 7/28/2007 21 Male 5/31/2011 Other Health Professional Mexico
Primary
Concomitant
Moyamoya Disease Other Serious 12/1/2005 29 Female 6/2/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2004 27 Female 84 lb 5/27/2011 Physician Japan
Primary
Concomitant
Lupus Nephritis Other Serious 35 Male 8/4/2011 Other Health Professional United States
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 35 Female 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspiration Hospitalization 61 Female 9/28/2011 United States
Primary
Concomitant
Depression Other Serious 59 Female 10/7/2011 Other Health Professional United States
Primary
Concomitant
Drug Interaction Other Serious 61 Male 10/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/1/2004 27 Female 84 lb 10/24/2011 Physician Japan
Primary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 35 Female 11/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Level Below Therapeutic Other Serious 35 Female 11/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Complications Of Transplanted Pancreas Other Serious 11/29/2011 Other Health Professional United States
Primary
Concomitant
Serum Sickness Other Serious 11/16/2009 36 Female 178 lb 12/5/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Arterial Hypertension Other Serious 9 Female 12/15/2011 Switzerland
Primary
Concomitant
Aspergillosis Other Serious Male 1/10/2012 Physician Hungary
Primary
Secondary
Multi-organ Failure Death Male 1/10/2012 Physician Hungary
Primary
Secondary
Chronic Graft Versus Host Disease Other Serious Male 1/10/2012 Physician Hungary
Primary
Secondary
Sepsis Death Female 1/10/2012 Physician Hungary
Primary
Secondary
Aspergillosis Other Serious 1/11/2012 Hungary
Primary
Secondary
Sepsis Other Serious Male 1/16/2012 Physician Hungary
Primary
Secondary
Chronic Graft Versus Host Disease Other Serious Male 1/16/2012 Physician Hungary
Primary
Secondary
Microangiopathy Other Serious Female 1/16/2012 Physician Hungary
Primary
Secondary
Multi-organ Failure Death Male 1/16/2012 Physician Hungary
Primary
Secondary
Respiratory Failure Death 2/24/2012 Physician China
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 31 Male 4/9/2012 Other Health Professional Spain
Primary
Secondary
Blood Creatinine Increased Other Serious 31 Male 4/9/2012 Other Health Professional Spain
Primary
Secondary
Hypertension Other Serious 47 Female 4/9/2012 Other Health Professional Spain
Primary
Secondary

Drug Data