Methycobal combined with Takepron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 7/1/2009 Female 128 lb 8/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 4/16/2009 Female 112 lb 8/26/2009 Physician Japan
Primary
Concomitant
Splenic Abscess Other Serious 11/2/2007 Female 79 lb 8/26/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2009 72 Male 8/26/2009 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/3/2009 66 Male 130 lb 8/31/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/22/2009 Male 9/8/2009 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/18/2009 Female 9/10/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/30/2008 65 9/29/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 5/1/2009 Female 141 lb 10/9/2009 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/18/2009 Female 10/9/2009 Physician Japan
Primary
Concomitant
Splenic Abscess Other Serious 11/2/2007 Female 79 lb 10/12/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/22/2009 Male 10/13/2009 Physician Japan
Primary
Concomitant
Pericardial Effusion Other Serious 4/16/2009 Female 112 lb 10/15/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/30/2008 65 10/20/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 5/1/2009 Female 141 lb 11/30/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Death 9/12/2009 65 Male 12/3/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2007 Male 103 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/30/2008 65 Male 119 lb 12/3/2009 Physician Japan
Primary
Concomitant
Death Death 9/25/2008 Male 91 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Life Threatening 5/1/2009 74 Male 123 lb 12/7/2009 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Hospitalization 11/1/2008 Female 1/8/2010 Japan
Primary
Concomitant
Lung Disorder Life Threatening 5/1/2009 75 Male 123 lb 1/14/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 Female 121 lb 1/19/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/30/2008 65 Male 119 lb 1/22/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/4/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/30/2009 Male 116 lb 2/8/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/9/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 5/1/2008 65 Male 123 lb 2/16/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/30/2008 65 Male 119 lb 2/18/2010 Physician Japan
Primary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 11/1/2008 Female 2/22/2010 Japan
Primary
Concomitant
Malaise Hospitalization 8/3/2009 Female 121 lb 2/25/2010 Physician Japan
Primary
Concomitant
Extranodal Marginal Zone B-cell Lymphoma (Malt Type) Hospitalization 11/1/2008 Female 3/18/2010 Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/30/2008 65 Male 119 lb 3/19/2010 Physician Japan
Primary
Concomitant
Ulnar Neuritis Other Serious 7/7/2009 40 Male 203 lb 4/14/2010 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 2/16/2010 72 Male 118 lb 4/23/2010 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Death 12/19/2008 81 Female 88 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious 11/25/2008 71 Female 99 lb 4/26/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Other Serious 12/13/2009 68 Female 121 lb 4/27/2010 Physician Japan
Primary
Concomitant
Nephropathy Hospitalization 2/17/2010 62 Female 4/29/2010 Other Health Professional Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/12/2006 58 Female 132 lb 7/6/2010 Japan
Primary
Secondary
Concomitant
Cough Hospitalization 2/1/2006 49 Female 128 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Appendicitis Hospitalization 5/16/2010 75 Female 84 lb 7/7/2010 Physician Japan
Primary
Concomitant
Ulnar Neuritis Other Serious 7/7/2009 40 Male 236 lb 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphopenia Other Serious 6/1/2009 71 Male 139 lb 7/9/2010 Physician Japan
Primary
Concomitant
Wound Infection Hospitalization 11/22/2008 58 Male 132 lb 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/2/2008 77 Male 7/12/2010 Physician Japan
Primary
Concomitant
Meralgia Paraesthetica Hospitalization 5/1/2008 47 Female 106 lb 7/12/2010 Physician Japan
Primary
Concomitant
Meralgia Paraesthetica Hospitalization 5/1/2008 47 Female 106 lb 7/13/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Other Serious 12/13/2009 68 Female 121 lb 7/27/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 11/25/2008 71 Female 99 lb 7/28/2010 Physician Japan
Primary
Concomitant
Liver Disorder Disability 3/23/2010 36 Female 173 lb 8/10/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 4/12/2010 66 Male 143 lb 8/11/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 6/15/2010 62 Male 126 lb 8/13/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 8/16/2010 Japan
Primary
Concomitant
Cardiac Failure Acute Death 8/2/2010 62 Female 8/17/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/15/2010 45 Female 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 8/2/2010 63 Female 9/2/2010 Physician Japan
Primary
Concomitant
Optic Neuritis Life Threatening 7/26/2008 36 Male 9/3/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 8/16/2010 78 Female 126 lb 9/3/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/15/2010 45 Female 9/7/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/5/2009 73 Male 92 lb 9/7/2010 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/18/2009 65 Female 9/8/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Encephalopathy Life Threatening 12/26/2009 67 Male 157 lb 9/8/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 8/16/2010 78 Female 126 lb 9/13/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 8/16/2010 78 Female 126 lb 9/15/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 8/16/2010 78 Female 126 lb 9/15/2010 Physician Japan
Primary
Concomitant
Generalised Oedema Other Serious 83 Female 9/17/2010 Pharmacist Japan
Primary
Concomitant
Vomiting Life Threatening 8/16/2010 78 Female 126 lb 9/20/2010 Physician Japan
Primary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 9/23/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 9/23/2010 Pharmacist Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 5/31/2010 62 Male 126 lb 9/24/2010 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/18/2009 65 Female 9/24/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/16/2010 78 Female 126 lb 10/1/2010 Physician Japan
Primary
Concomitant
Generalised Oedema Other Serious 83 Female 10/1/2010 Pharmacist Japan
Primary
Concomitant
Wound Infection Hospitalization 11/22/2008 58 Male 132 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Sputum Culture Positive Death 4/30/2009 71 Male 116 lb 10/7/2010 Physician Japan
Primary
Concomitant
Hypoaesthesia Other Serious 3/2/2010 54 Male 126 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 60 Female 121 lb 12/13/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 10/12/2010 55 Female 88 lb 12/16/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 3/2/2010 55 Female 88 lb 12/22/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 10/7/2010 64 Male 119 lb 12/27/2010 Physician Japan
Primary
Concomitant
Lymphopenia Hospitalization 2/4/2009 71 Male 137 lb 12/28/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 12/28/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 4/30/2009 83 Female 97 lb 12/29/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 3/23/2010 36 Female 173 lb 1/25/2011 Physician Japan
Primary
Concomitant
Disease Progression Death 2/2/2008 1/26/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 3/3/2010 61 Female 134 lb 1/31/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Other Serious 9/14/2010 68 Female 76 lb 2/2/2011 Physician Japan
Primary
Concomitant
Infection Hospitalization 2/2/2008 2/18/2011 Physician Japan
Primary
Concomitant
Anal Ulcer Haemorrhage Hospitalization 6/30/2008 77 Female 2/23/2011 Other Health Professional Japan
Primary
Concomitant
Agranulocytosis Life Threatening 2/1/2010 72 Female 95 lb 3/2/2011 Physician Japan
Primary
Secondary
Concomitant
Abscess Jaw Hospitalization 12/7/2010 55 Female 97 lb 3/4/2011 Physician Japan
Primary
Concomitant
Renal Failure Death 10/24/2010 86 Male 93 lb 3/8/2011 Consumer Japan
Primary
Concomitant
Abscess Jaw Hospitalization 12/7/2010 55 Female 97 lb 3/18/2011 Physician Japan
Primary
Concomitant
Cancer Pain Life Threatening 10/24/2010 86 Male 93 lb 3/18/2011 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/24/2011 54 Male 126 lb 3/21/2011 Pharmacist Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 10/13/2010 54 Male 126 lb 3/22/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/30/2008 77 Female 3/23/2011 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 9/1/2010 47 Male 150 lb 4/1/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/16/2010 76 Female 4/13/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/4/2010 56 Male 132 lb 4/13/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Death 6/12/2009 70 Male 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/24/2011 54 Male 126 lb 4/29/2011 Pharmacist Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 10/13/2010 54 Male 126 lb 5/3/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/30/2009 71 Male 116 lb 4/22/2013 Physician Jp
Primary
Concomitant
Thrombocytopenia Hospitalization 8/5/2009 74 Male 92 lb 8/29/2012 Physician Jp
Primary
Concomitant
Lymphoma Other Serious 4/7/2010 45 Female 9/5/2012 Country Not Specified
Primary
Concomitant
Intentional Drug Misuse Other Serious 6/16/2010 75 Male 141 lb 2/27/2013 Physician Jp
Primary
Secondary
Concomitant
Peritonitis Other Serious 1/22/2011 73 Male 4/16/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/24/2011 77 Male 11/21/2012 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/25/2010 62 Female 135 lb 12/21/2012 Physician Jp
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 7/14/2011 79 Male 132 lb 9/28/2012 Pharmacist Jp
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 3/5/2009 65 Male 121 lb 3/14/2013 Physician Jp
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/28/2009 81 Female 3/5/2013 Physician Jp
Primary
Concomitant
Bronchopneumonia Hospitalization 12/5/2011 72 Female 123 lb 12/10/2012 Physician Jp
Primary
Secondary
Concomitant
Rash Disability 6/27/2011 72 Female 11/16/2012 Physician Jp
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/12/2012 64 Female 99 lb 10/5/2012 Physician Jp
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 12/9/2011 75 Female 104 lb 9/6/2012 Physician Jp
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/23/2012 65 Female 140 lb 10/26/2012 Pharmacist Jp
Primary
Concomitant
Vitreous Disorder Hospitalization 3/7/2012 44 Male 218 lb 10/31/2012 Physician Jp
Primary
Concomitant
Pain Hospitalization 10/30/2010 35 Female 106 lb 12/12/2012 Country Not Specified
Primary
Concomitant
Renal Failure Acute Hospitalization 2/22/2012 61 Male 143 lb 3/15/2013 Physician Jp
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/25/2012 67 Female 112 lb 10/9/2012 Physician Jp
Primary
Secondary
Concomitant
Proctalgia Other Serious 7/23/2012 67 Male 9/7/2012 Physician Jp
Primary
Concomitant
Renal Impairment Hospitalization 8/27/2012 70 Female 137 lb 4/27/2013 Consumer Jp
Primary
Secondary
Concomitant
Vomiting 8/23/2012 63 NotSpecified 95 lb 5/1/2013 Physician Jp
Primary
Concomitant
Renovascular Hypertension Hospitalization 9/6/2011 80 Female 128 lb 1/9/2013 Physician Jp
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious Male 12/19/2012 Physician Jp
Primary
Concomitant
Stomatitis Hospitalization 11/17/2011 69 Female 112 lb 10/5/2012 Country Not Specified
Primary
Concomitant
Rash Hospitalization 8/2010 Female 10/9/2012 Consumer Jp
Primary
Concomitant
Stomatitis Hospitalization 8/23/2012 53 Female 104 lb 5/27/2013 Consumer Jp
Primary
Secondary
Concomitant
Sepsis Other Serious 2009 Male 126 lb 1/4/2013 Physician Jp
Primary
Concomitant
Renal Impairment Disability 1/7/2013 77 Female 1/30/2013 Physician Jp
Primary
Secondary
Concomitant
Cerebellar Atrophy Other Serious 57 Male 1/25/2013 Pharmacist Jp
Primary
Concomitant
Vomiting Other Serious 3/2/2012 58 Female 86 lb 2/4/2013 Consumer Jp
Primary
Secondary
Concomitant
Renovascular Hypertension Hospitalization 9/6/2011 80 Female 128 lb 2/5/2013 Other Health Professional Jp
Primary
Concomitant
Face Oedema 1/12/2013 Male 121 lb 3/14/2013 Physician Jp
Primary
Secondary
Concomitant
Sepsis Death 4/30/2012 Male 3/8/2013 Physician Jp
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 10/3/2012 69 Male 143 lb 4/11/2013 Physician Jp
Primary
Secondary
Concomitant
Restlessness Other Serious 2/1/2013 80 Female 117 lb 3/12/2013 Physician Jp
Primary
Concomitant
Liver Function Test Abnormal Death 1/22/2013 74 Male 4/23/2013 Physician Jp
Primary
Secondary
Concomitant
Somnolence Other Serious 2/2013 51 Female 4/8/2013 Physician Jp
Primary
Concomitant
Spinal Compression Fracture Hospitalization 2/5/2009 64 Male 121 lb 3/21/2013 Physician Jp
Primary
Secondary
Concomitant
Liver Function Test Abnormal Life Threatening 3/8/2013 76 Female 90 lb 5/16/2013 Consumer Jp
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/24/2011 71 Female 4/1/2013 Physician Jp
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/25/2013 79 Male 5/9/2013 Pharmacist Jp
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/2011 61 Male 146 lb 5/10/2013 Pharmacist Jp
Primary
Concomitant
Erythema Multiforme Other Serious 4/18/2013 72 Female 106 lb 6/14/2013 Physician Jp
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 9/22/2011 38 Female 91 lb 10/24/2012 Consumer Jp
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/25/2012 67 Female 112 lb 10/25/2012 Other Health Professional Jp
Primary
Secondary
Concomitant

Drug Data