Methadone combined with Seroquel

Reports:

---

Reaction	Outcome	Event Date	Age	Sex	Weight	Reported	Reporter	Country	Treatment
									Role	Name
Renal Tubular Necrosis	Hospitalization		44	Male		1/17/2006	Other Health Professional	United States	Primary Secondary Concomitant
Ventricular Extrasystoles	Hospitalization		43	Female		2/7/2006	Pharmacist	United States	Primary Secondary Concomitant
Weight Decreased	Required Intervention	4/23/2005	48	Female	152 lb	5/26/2006	Consumer	United States	Primary Secondary Concomitant
Somnolence	Death	5/5/2006	41	Female	248 lb	10/18/2006	Physician	United States	Primary Concomitant Interacting
Ill-defined Disorder	Hospitalization			Male		10/20/2006	Physician	United States	Primary Concomitant
Vision Blurred	Other Serious		50	Male	140 lb	1/31/2007		United States	Primary Concomitant
Weight Decreased	Other Serious	1/1/2001	42	Female	140 lb	11/19/2007	Other Health Professional	United States	Primary Concomitant
Death	Death	10/1/2007		Male	167 lb	11/21/2007	Other Health Professional	United States	Primary Secondary Concomitant
Withdrawal Syndrome	Other Serious	1/4/2003		Male		11/27/2007	Other Health Professional	United States	Primary Concomitant
Withdrawal Syndrome	Other Serious	1/4/2003		Male		11/28/2007	Other Health Professional	United States	Primary Concomitant
Lung Cancer Metastatic	Death	10/1/2007		Male	167 lb	12/6/2007	Other Health Professional	United States	Primary Secondary Concomitant
Road Traffic Accident	Death	11/23/2007	36	Female	200 lb	3/14/2008		United States	Primary Secondary Concomitant
Tongue Biting	Other Serious	1/1/2005		Female		3/24/2009	Consumer	United States	Primary Concomitant
Type 2 Diabetes Mellitus	Death	1/1/1996	45	Male		4/2/2009		United States	Primary Concomitant
Weight Increased	Other Serious	9/11/2002	41	Male	234 lb	4/3/2009		United States	Primary Concomitant
Weight Increased	Other Serious	8/1/2005	42	Female	257 lb	4/3/2009		United States	Primary Concomitant
Tearfulness	Other Serious	8/11/2004	60	Female	160 lb	4/3/2009		United States	Primary Concomitant
Vomiting	Hospitalization	9/1/2003	47	Male	298 lb	4/7/2009		United States	Primary Concomitant
Suicide Attempt	Other Serious	3/27/2009	33	Female	148 lb	4/16/2009	Physician	Switzerland	Primary Concomitant Interacting
Rectal Discharge	Other Serious	1/1/2008		Female	135 lb	4/17/2009	Consumer	United States	Primary Concomitant
Suicide Attempt	Other Serious	3/27/2009	33	Female	148 lb	4/28/2009	Physician	Switzerland	Primary Concomitant Interacting
Cardiac Arrest	Death	3/17/2009		Male	270 lb	4/29/2009	Consumer	United States	Primary Secondary Concomitant
Wound Dehiscence	Hospitalization	7/19/2001	45	Female	189 lb	4/29/2009		United States	Primary Concomitant
Migraine		12/10/2008		Male		5/4/2009	Consumer	United States	Primary Concomitant
Unevaluable Event				Male		5/4/2009	Physician	United States	Primary Secondary Concomitant
Neuropathy Peripheral	Other Serious	10/13/2008	48	Female	245 lb	5/7/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	3/8/2001	49	Female	270 lb	5/19/2009		United States	Primary Concomitant
Wound Infection	Other Serious	1/1/2001	42	Male	240 lb	5/20/2009		United States	Primary Secondary Concomitant
Uterine Leiomyoma	Other Serious	1/1/2001	42	Female	124 lb	5/20/2009		United States	Primary Concomitant
Insulin-requiring Type 2 Diabetes Mellitus	Other Serious	4/29/2002	50	Female	388 lb	6/1/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	7/1/2003	39	Female	148 lb	6/17/2009		United States	Primary Concomitant
Phlebitis	Other Serious	9/16/2004	54	Female	167 lb	6/19/2009		United States	Primary Concomitant
Staphylococcal Infection	Hospitalization	5/28/2009	66	Male	143 lb	6/22/2009	Other Health Professional	United States	Primary Secondary Concomitant
Type 2 Diabetes Mellitus	Hospitalization	1/1/2003	61	Female	215 lb	6/30/2009		United States	Primary Concomitant
Peripheral Nerve Decompression	Other Serious	1/1/2005	53	Female	128 lb	7/1/2009		United States	Primary Concomitant
Pruritus Generalised		6/9/2009	52	Female	154 lb	7/8/2009	Other Health Professional	United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	6/1/2004	46	Female	167 lb	7/9/2009		United States	Primary Concomitant
Tongue Biting	Other Serious	1/1/2005		Female		7/9/2009	Consumer	United States	Primary Concomitant
Type 1 Diabetes Mellitus	Other Serious	2/1/2006	53	Male	186 lb	7/10/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	7/2/2002	52	Male		7/10/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	12/1/2005	53	Female	200 lb	8/6/2009		United States	Primary Concomitant
Neuropathy Peripheral	Other Serious	1/30/2003	49	Female	155 lb	8/7/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	3/1/2001	49	Female	290 lb	8/13/2009		United States	Primary Concomitant
Respiratory Tract Congestion	Other Serious	1/1/2009	37	Male	265 lb	8/14/2009	Pharmacist	Canada	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/1/2006	48	Female	201 lb	8/25/2009		United States	Primary Concomitant
Pulmonary Congestion	Hospitalization	7/10/2007	45	Female		8/28/2009		United States	Primary Concomitant
Vomiting	Other Serious	1/1/2005	47	Male	208 lb	8/31/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	9/22/2005	42	Male	205 lb	8/31/2009		United States	Primary Concomitant
Vision Blurred	Other Serious	1/1/2004	49	Female		9/10/2009		United States	Primary Concomitant
Myocardial Ischaemia	Other Serious	11/25/1997	48	Female	196 lb	9/10/2009		United States	Primary Concomitant
Pancreatitis	Other Serious	1/1/2007	54	Male	164 lb	9/23/2009		United States	Primary Concomitant
Type 1 Diabetes Mellitus	Other Serious	11/30/2005	43	Female	329 lb	9/23/2009		United States	Primary Concomitant
Weight Increased	Other Serious	4/1/2001	42	Male	211 lb	9/23/2009		United States	Primary Concomitant
Myositis		4/19/2000	60	Female	248 lb	9/23/2009		United States	Primary Concomitant
Diabetes Mellitus	Hospitalization			Female	212 lb	9/23/2009		United States	Primary Concomitant
Tardive Dyskinesia	Other Serious	1/1/2003	46	Female	288 lb	9/23/2009		United States	Primary Concomitant
Pancreatitis	Other Serious			Female	256 lb	9/23/2009		United States	Primary Concomitant
Visual Acuity Reduced	Hospitalization	7/9/2005	52	Female	153 lb	9/23/2009		United States	Primary Concomitant
Diabetes Mellitus	Disability			Male	293 lb	9/23/2009	Other Health Professional	United States	Primary Concomitant
Toothache	Hospitalization	4/13/2004	42	Male	214 lb	9/23/2009		United States	Primary Concomitant
Bone Pain				Female		9/24/2009	Consumer	United States	Primary Concomitant
Drug Screen Positive		1/1/2008	38	Female		9/24/2009	Other Health Professional	United States	Primary Concomitant
Pancreatitis	Other Serious	7/1/2008	19	Male	185 lb	9/24/2009	Physician	United States	Primary Concomitant
Sleep Disorder	Other Serious	5/1/2009	29	Male		9/28/2009	Physician	United States	Primary Concomitant
Nerve Block	Other Serious	9/9/2009	28	Female		10/2/2009	Consumer	United States	Primary Concomitant
Staphylococcal Infection	Hospitalization	9/1/2009		Male		10/5/2009	Other Health Professional	United States	Primary Concomitant
Neonatal Respiratory Distress Syndrome	Other Serious	4/28/2009		Male		10/22/2009	Physician	Denmark	Primary Secondary Concomitant
Type 2 Diabetes Mellitus	Other Serious	3/1/2001	49	Female	290 lb	10/29/2009		United States	Primary Concomitant
Death	Death	10/26/2009		Male		10/29/2009	Physician	United States	Primary Secondary
Staphylococcal Infection	Hospitalization	9/23/2009				10/30/2009	Consumer	United States	Primary Concomitant
Staphylococcal Infection	Hospitalization	9/23/2009				11/6/2009	Consumer	United States	Primary Concomitant
Respiratory Arrest	Death	9/30/2009	47	Male	195 lb	11/6/2009	Physician	United States	Primary Secondary Concomitant
Tongue Biting	Other Serious	1/1/2005		Female		12/1/2009	Consumer	United States	Primary Concomitant
Weight Increased	Other Serious	1/1/2004	32	Female	149 lb	1/8/2010		United States	Primary Concomitant
Staphylococcal Infection	Hospitalization	9/23/2009				1/24/2010	Consumer	United States	Primary Concomitant
No Adverse Event						1/25/2010	Physician	United States	Primary Secondary
Neuropathy Peripheral	Other Serious	1/1/2007	47	Female	254 lb	1/29/2010		United States	Primary Concomitant
Completed Suicide	Death	11/17/2009	38	Male		1/29/2010	Physician	Switzerland	Primary Secondary Interacting
Neuropathy Peripheral	Other Serious	1/1/2007	47	Female	254 lb	2/2/2010		United States	Primary Concomitant
Pain In Extremity	Death	11/12/2009	38	Male		2/1/2010		Switzerland	Primary Secondary Interacting
Completed Suicide	Death	8/1/2007	35	Male		2/4/2010	Consumer	United States	Primary Concomitant
Weight Increased	Other Serious	1/1/2004	32	Female	149 lb	2/22/2010		United States	Primary Concomitant
Paranoid Personality Disorder	Other Serious	1/1/2007	47	Female	254 lb	2/23/2010		United States	Primary Concomitant
Myocardial Infarction	Life Threatening	10/29/2008		Male		2/23/2010	Other Health Professional	Canada	Primary Secondary Concomitant
Weight Increased	Other Serious	1/1/2004	32	Female	149 lb	2/25/2010		United States	Primary Concomitant
Hepatic Failure	Death		40	Male		3/8/2010	Physician	United States	Primary Concomitant
Weight Increased	Other Serious	1/1/2004	32	Female	149 lb	3/15/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	11/1/2004	49	Male	185 lb	5/13/2010		United States	Primary Concomitant
Weight Increased	Other Serious	1/1/2001	45	Female	164 lb	5/20/2010		United States	Primary Concomitant
Vomiting	Hospitalization	9/1/2003	47	Male	298 lb	5/27/2010		United States	Primary Concomitant
Weight Increased	Other Serious	1/1/2006	58	Male	310 lb	5/31/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	8/25/2002	43	Male	257 lb	6/1/2010		United States	Primary Concomitant
Diabetic Neuropathy	Other Serious	1/18/2006		Female	163 lb	6/1/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/1/2002	50	Male	248 lb	6/8/2010		United States	Primary Secondary Concomitant
Hypertension	Other Serious	4/1/2010	59	Female	251 lb	6/9/2010	Physician	United States	Primary Concomitant
Vomiting	Other Serious	1/1/2005	47	Male	208 lb	6/16/2010		United States	Primary Concomitant
Overdose	Other Serious	5/1/2005	34	Male	232 lb	6/18/2010		United States	Primary Concomitant
Weight Increased	Other Serious	5/1/2007	22	Male	210 lb	6/21/2010		United States	Primary Concomitant
Hypoglycaemia Neonatal	Hospitalization	8/11/2009				6/18/2010	Physician	Switzerland	Primary Concomitant
Failed Trial Of Labour	Other Serious	11/1/2008	40	Female		6/18/2010	Physician	Switzerland	Primary Concomitant
Type 1 Diabetes Mellitus	Other Serious	9/1/2002	38	Female	200 lb	6/23/2010		United States	Primary Secondary Concomitant
Spinal Deformity	Other Serious	5/1/2005	34	Male	143 lb	7/2/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/1/2002	48	Female	170 lb	7/2/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	11/15/2004		Male		7/7/2010		United States	Primary Concomitant
Drug Screen False Positive		5/30/2007		Female		7/7/2010	Consumer	United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/1/2002	45	Male	210 lb	7/9/2010		United States	Primary Secondary Concomitant
Headache	Death	12/21/2002	35	Male		8/6/2010	Other Health Professional	Australia	Primary Secondary Concomitant
Hypertension	Other Serious	8/1/2010	31	Male	174 lb	8/17/2010	Consumer	United States	Primary Concomitant
Suicide Attempt	Other Serious	8/11/2007	30	Female		8/24/2010	Lawyer	United States	Primary Concomitant
White Blood Cell Count Increased	Other Serious			Female	188 lb	8/26/2010	Physician	United States	Primary Secondary Concomitant
Vomiting	Hospitalization	7/1/2010	35	Female	280 lb	8/27/2010	Other Health Professional	Canada	Primary Concomitant
White Blood Cell Count Increased	Other Serious			Female	188 lb	8/30/2010	Physician	United States	Primary Secondary Concomitant
Weight Increased	Other Serious	1/1/2008	53	Male	280 lb	9/1/2010	Consumer	United States	Primary Concomitant
Uterine Leiomyoma	Other Serious	7/1/2002	44	Female	115 lb	9/9/2010		United States	Primary Concomitant
Drug Ineffective		11/1/2008		Male		9/14/2010	Other Health Professional	United States	Primary Concomitant
White Blood Cell Count Increased	Other Serious			Female	188 lb	9/15/2010	Other Health Professional	United States	Primary Secondary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/12/2001	52	Male	175 lb	9/17/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Hospitalization	6/1/2004	51	Female	158 lb	9/17/2010		United States	Primary Concomitant
Pancreatitis	Other Serious	1/1/2005	67	Female	175 lb	9/17/2010		United States	Primary Concomitant
Pancreatitis	Hospitalization	8/1/2007	49	Male		9/17/2010		United States	Primary Concomitant
Hyperglycaemia	Other Serious	1/1/2006	44	Male	187 lb	9/17/2010		United States	Primary Concomitant
Fatigue		10/1/2009	56	Female	135 lb	9/18/2010	Consumer	United States	Primary Concomitant
Pancreatitis	Other Serious	7/6/2008	42	Female	280 lb	9/20/2010		United States	Primary Concomitant
Diabetes Mellitus	Hospitalization	11/25/2004	46	Male	176 lb	9/20/2010		United States	Primary Concomitant
Pancreatitis	Other Serious	11/1/2006	30	Female	283 lb	9/20/2010		United States	Primary Concomitant
Pancreatitis Acute	Hospitalization	8/26/2004	54	Female	100 lb	9/20/2010		United States	Primary Concomitant
Pancreatitis	Other Serious			Female	110 lb	9/20/2010		United States	Primary Concomitant
Type 1 Diabetes Mellitus	Other Serious	11/19/1999	44	Female	181 lb	9/20/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/1/2007	49	Male	230 lb	9/20/2010		United States	Primary Concomitant
Limb Injury		6/3/2010	53	Male	200 lb	9/20/2010	Consumer	United States	Primary Concomitant
Pancreatitis	Other Serious	5/23/2006	48	Female	280 lb	9/20/2010		United States	Primary Concomitant
Obesity	Hospitalization	6/1/2006	51	Male	250 lb	9/20/2010		United States	Primary Concomitant
Diabetic Coma	Other Serious	1/1/2005	50	Male	190 lb	9/20/2010		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	9/14/2005	66	Female	152 lb	9/20/2010		United States	Primary Secondary Concomitant
Pancreatitis Acute	Other Serious	12/28/2002	28	Female	256 lb	9/20/2010		United States	Primary Concomitant
Tardive Dyskinesia	Other Serious	1/1/2003	46	Female	288 lb	9/20/2010		United States	Primary Concomitant
Teeth Brittle	Other Serious	2/21/2001	42	Female	159 lb	9/20/2010		United States	Primary Concomitant
Weight Decreased	Other Serious	8/8/2000	25	Female		10/4/2010	Physician	United States	Primary Secondary Concomitant
Panic Reaction	Other Serious	9/27/2010	35	Female	289 lb	10/7/2010	Other Health Professional	Canada	Primary Concomitant
Weight Decreased	Other Serious	8/8/2000	25	Female		10/12/2010	Physician	United States	Primary Secondary Concomitant
White Blood Cell Count Increased	Other Serious	1/1/2002	50	Female	188 lb	10/12/2010	Other Health Professional	United States	Primary Secondary Concomitant
Thrombocytopenia	Other Serious	6/1/2010	51	Female		10/13/2010	Physician	Switzerland	Primary Concomitant
Renal Tubular Necrosis	Hospitalization	6/1/2010	51	Female		10/15/2010	Consumer	United States	Primary Secondary Concomitant
Wheezing	Life Threatening	5/31/2010	56	Female		10/15/2010	Physician		Primary Secondary Concomitant
Renal Tubular Necrosis	Hospitalization	6/1/2010	51	Female		10/18/2010	Consumer	United States	Primary Secondary Concomitant
White Blood Cell Count Increased	Other Serious	1/1/2002	50	Female	188 lb	10/25/2010	Other Health Professional	United States	Primary Secondary Concomitant
Thrombocytopenia	Other Serious	6/1/2010	51	Female		10/25/2010	Physician	Switzerland	Primary Concomitant
Wheezing	Life Threatening	5/31/2010	56	Female		11/3/2010	Physician		Primary Secondary Concomitant
Weight Decreased	Other Serious	8/8/2000	25	Female		11/24/2010	Physician	United States	Primary