Methadone combined with Promethazine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Troponin I Increased 11/23/2004 53 Female 207 lb 1/27/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2005 43 Male 223 lb 1/20/2006 United States
Primary
Concomitant
Vomiting Hospitalization 3/6/2006 46 Male 154 lb 4/12/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 3 Female 162 lb 11/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2007 37 Male 12/24/2008 Physician United States
Primary
Secondary
Pancytopenia Hospitalization 7/23/2007 Female 149 lb 3/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Death 1/1/1996 45 Male 4/2/2009 United States
Primary
Concomitant
Rhabdomyolysis Other Serious Female 4/2/2009 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 7/23/2007 38 Female 148 lb 4/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2001 42 Male 240 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 5/11/2009 Female 5/22/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 5/1/2009 19 Male 149 lb 5/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Blood Glucose Abnormal Female 5/27/2009 United States
Primary
Concomitant
Urinary Tract Infection 4/1/2009 72 Male 260 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Other Serious 5/11/2009 Female 6/29/2009 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 11/25/1997 48 Female 196 lb 9/10/2009 United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 7/9/2005 52 Female 153 lb 9/23/2009 United States
Primary
Concomitant
Pneumonia Other Serious 10/15/2007 Female 144 lb 11/30/2009 Consumer United States
Primary
Concomitant
Venous Insufficiency Life Threatening 1/8/2010 Female 142 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 55 Female 1/26/2010 United States
Primary
Secondary
Thrombocytopenia Hospitalization 1/8/2010 49 Female 142 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2008 51 Male 2/3/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 55 Female 2/3/2010 Physician United States
Primary
Secondary
Death Death 55 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Oesophageal Carcinoma Hospitalization Male 140 lb 3/3/2010 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2007 Female 3/26/2010 Physician United States
Primary
Concomitant
Withdrawal Syndrome 3/31/2009 49 Male 147 lb 3/30/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2003 31 Female 5/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 3/4/1996 25 Female 5/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 7/6/2008 42 Female 280 lb 9/20/2010 United States
Primary
Concomitant
Vaginitis Bacterial Other Serious 3/4/1996 25 Female 9/28/2010 Pharmacist United States
Primary
Secondary
Concomitant
Sputum Discoloured 8/1/2009 68 Male 175 lb 10/13/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/30/2009 28 Male 103 lb 11/2/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 30 Female 11/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization Male 103 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Nephrosclerosis Required Intervention 4/18/2008 59 Female 125 lb 11/23/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 30 Female 12/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/26/1999 74 Female 192 lb 12/22/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/1/2002 39 Male 173 lb 12/22/2010 United States
Primary
Concomitant
Protein Total Decreased Hospitalization 6/5/2010 40 Male 210 lb 12/7/2010 Physician United States
Primary
Secondary
Concomitant
Radiculitis Lumbosacral Hospitalization 3/4/1996 25 Female 1/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Confusional State Other Serious Male 1/24/2011 Physician United Kingdom
Primary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 1/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/17/2011 48 Male 201 lb 1/20/2011 Pharmacist United States
Primary
Concomitant
Platelet Count Increased Hospitalization Male 103 lb 2/1/2011 Other Health Professional United States
Primary
Concomitant
Generalised Oedema Hospitalization 5/9/1997 37 Female 193 lb 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 3/1/2011 United States
Primary
Secondary
Concomitant
Purpura Hospitalization Male 103 lb 2/16/2011 Other Health Professional United States
Primary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/16/2010 14 Female 130 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 1/3/2011 40 Male 3/31/2011 Physician United Kingdom
Primary
Concomitant
Back Pain Other Serious 5/9/1997 37 Female 193 lb 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Contusion Hospitalization 11/1/2008 27 Male 4/8/2011 Lawyer United States
Primary
Concomitant
Tremor Other Serious 4/13/2011 77 Female 160 lb 4/20/2011 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/1/2002 39 Male 173 lb 4/28/2011 Pharmacist United States
Primary
Concomitant
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/9/1997 37 Female 193 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 1/1/2011 64 Female 130 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 1/1/2011 64 Female 130 lb 8/22/2011 Other Health Professional United States
Primary
Concomitant
Headache 1/1/2011 53 Male 251 lb 4/2/2012 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Other Serious Male 4/3/2012 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious Male 5/24/2012 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 2/23/2010 53 Female 154 lb 6/20/2012 Lawyer United States
Primary
Concomitant
Completed Suicide Death 2007 37 Male 5/28/2013 Physician Us
Primary
Secondary
Vomiting Hospitalization 7/14/2009 68 Male 11/28/2012 Physician Us
Primary
Secondary
Concomitant
Tendinous Contracture Other Serious 2003 31 Female 132 lb 3/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious Female 200 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Tremor Other Serious Female 10/8/2012 Lawyer Us
Primary
Concomitant
Oesophagitis Other Serious Female 192 lb 10/31/2012 Lawyer Us
Primary
Concomitant
Thrombosis Other Serious 2009 28 Female 260 lb 5/10/2013 Consumer Us
Primary
Concomitant
Spinal Disorder Other Serious 39 Male 10/12/2012 Consumer Us
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/23/2012 54 Female 162 lb 11/13/2012 Physician Us
Primary
Concomitant
Septic Shock Hospitalization 8/1/2012 20 Female 10/25/2012 Other Health Professional Us
Primary
Concomitant
Death Death 2005 63 9/28/2012 Other Health Professional Country Not Specified
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 2009 57 Male 198 lb 10/11/2012 Other Health Professional Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2009 55 Male 198 lb 10/15/2012 Consumer Us
Primary
Secondary
Concomitant
Rash Hospitalization Female 155 lb 11/9/2012 Consumer Us
Primary
Secondary
Concomitant
Drug Abuse Death 19 10/29/2012 Other Health Professional Country Not Specified
Primary
Secondary
Drug Abuse Death 28 10/29/2012 Other Health Professional Country Not Specified
Primary
Secondary
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Paraesthesia 6/27/2011 44 226 lb 11/7/2012 Other Health Professional Us
Primary
Concomitant
Weight Decreased Other Serious Female 107 lb 11/22/2012 Physician Us
Primary
Concomitant
Pruritus Other Serious 11/13/2012 27 Male 11/18/2012 Pharmacist Us
Primary
Concomitant
Unresponsive To Stimuli Other Serious 43 Female 12/7/2012 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 40 Male 12/12/2012 Consumer Us
Primary
Secondary
Toxicity To Various Agents Death 40 Male 12/13/2012 Other Health Professional Us
Primary
Secondary
Product Quality Issue Other Serious 12/6/2006 46 Male 218 lb 12/28/2012 Consumer Us
Primary
Concomitant
Respiratory Arrest Death 2011 41 Male 1/6/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 49 Male 1/8/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 40 Male 1/8/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 39 Female 1/8/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 40 Male 1/8/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 50 Female 1/9/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 49 Male 1/9/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 34 Male 1/8/2013 Physician Us
Primary
Secondary
Drug Abuse Death 2011 42 Female 10/18/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 40 Male 1/18/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Hospitalization 49 Male 1/18/2013 Physician Us
Primary
Secondary
Pollakiuria 5/24/2012 Female 1/19/2013 Physician Country Not Specified
Primary
Concomitant
Toxicity To Various Agents Death 34 Male 1/19/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 39 Female 1/20/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Hospitalization 49 Male 1/20/2013 Physician Us
Primary
Secondary
Drug Abuse Other Serious 42 Female 1/18/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 23 Male 1/18/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 34 Male 1/25/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 39 Female 1/25/2013 Physician Us
Primary
Secondary
Drug Abuse Death 42 Female 1/25/2013 Physician Us
Primary
Secondary
Drug Abuse Death 42 Female 1/11/2013 Other Health Professional Us
Primary
Secondary
Respiratory Arrest Other Serious 39 Female 1/11/2013 Physician Us
Primary
Secondary
Thyroid Disorder Other Serious 1/9/2013 65 Female 180 lb 1/29/2013 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Death 34 Male 1/11/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 49 Male 1/16/2013 Physician Us
Primary
Secondary
Withdrawal Syndrome 51 Female 3/14/2013 Consumer Us
Primary
Concomitant
Intentional Drug Misuse Death 41 Male 2/8/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Other Serious 41 Male 1/17/2013 Physician Us
Primary
Secondary
Drug Abuse Death 42 Female 1/16/2013 Physician Us
Primary
Secondary
Overdose Death NotSpecified 2/14/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 49 Male 1/28/2013 Physician Us
Primary
Secondary
Cardio-respiratory Arrest Death 2011 40 Male 2/15/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 49 Male 2/15/2013 Physician Us
Primary
Secondary
Pyrexia 8/23/2012 51 Female 1/31/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Sleep Disorder 5/2012 63 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Weight Increased Other Serious Female 177 lb 2/21/2013 Consumer Country Not Specified
Primary
Concomitant
Intentional Drug Misuse Other Serious 49 Male 2/8/2013 Other Health Professional Us
Primary
Secondary
Intentional Drug Misuse Death 49 Male 2/8/2013 Other Health Professional Us
Primary
Secondary
Intentional Drug Misuse Death 40 Male 2/7/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 23 Male 2/26/2013 Physician Country Not Specified
Primary
Secondary
Toxicity To Various Agents Death 49 Male 2/28/2013 Physician Country Not Specified
Primary
Secondary
Poisoning Death 2011 42 Female 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 49 Male 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 34 Male 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 52 Female 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 50 Female 2/4/2013 Physician Us
Primary
Secondary
Drug Ineffective 41 Female 201 lb 3/6/2013 Consumer Us
Primary
Secondary
Concomitant
Respiratory Arrest Death 2011 40 Male 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 23 Male 2/4/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 2011 41 Male 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 39 Female 2/4/2013 Physician Us
Primary
Secondary
Withdrawal Syndrome Other Serious 10/2012 41 Female 201 lb 3/7/2013 Consumer Us
Primary
Concomitant
Death Death 34 10/29/2012 Other Health Professional Country Not Specified
Primary
Secondary
Visual Impairment Other Serious Female 104 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Toxicity To Various Agents Hospitalization 49 Male 1/23/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 34 Male 1/23/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 39 Female 1/23/2013 Us
Primary
Secondary
Wound Dehiscence Other Serious 6/2002 Male 173 lb 9/28/2012 Consumer Us
Primary
Concomitant
Wound Dehiscence Hospitalization 6/2002 Male 173 lb 2/15/2013 Consumer Us
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2003 Female 10/10/2012 Consumer Us
Primary
Concomitant

Drug Data