Methadone Hcl combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Torsade De Pointes Hospitalization 1/13/2006 53 Female 2/9/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2005 60 Male 200 lb 2/8/2006 United States
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2005 72 Male 1/23/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2005 72 Male 1/31/2006 Consumer United States
Primary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 4/11/2006 Consumer Thailand
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 6/1/2001 43 Male 4/27/2006 Consumer United States
Primary
Concomitant
Osteoporosis Required Intervention 1/1/2001 44 Female 120 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 3/27/2006 68 Male 4/25/2006 Physician United States
Primary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 4/28/2006 Physician Thailand
Primary
Secondary
Concomitant
Pain Hospitalization 4/18/2006 Female 129 lb 5/12/2006 Consumer United States
Primary
Concomitant
Shock Other Serious 2/1/2006 23 Male 170 lb 5/12/2006 Physician Thailand
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 5/12/2006 United States
Primary
Concomitant
Vomiting Death Female 5/19/2006
Primary
Secondary
Self-medication Hospitalization 4/18/2006 33 Female 129 lb 5/16/2006 United States
Primary
Concomitant
Pain Hospitalization 4/18/2006 Female 129 lb 5/30/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 2/27/2005 77 Female 5/25/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2005 72 Male 4/6/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 35 Male 350 lb 2/10/2006 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 56 Male 150 lb 4/20/2006 United States
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 6/14/2006 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/1998 15 Female 6/13/2006 Consumer Australia
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 6/30/2006 United States
Primary
Concomitant
Porphyria Acute Required Intervention 1/1/2001 39 Female 7/17/2006 Consumer United States
Primary
Secondary
Concomitant
Porphyria Acute Required Intervention 1/1/2001 39 Female 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Immune System Disorder Required Intervention 1/1/2001 44 Female 120 lb 8/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoporosis Required Intervention 1/1/2001 39 Female 120 lb 8/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Other Serious 7/16/2006 75 Male 120 lb 7/16/2006 Pharmacist United States
Primary
Secondary
Sedation Hospitalization 61 Female 8/19/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 8/21/2006 United States
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 9/6/2006 United States
Primary
Concomitant
Multiple Drug Overdose Intentional Death 43 Female 9/14/2006 Physician United States
Primary
Secondary
Respiratory Rate Increased Other Serious 41 Male 9/13/2006 Other Health Professional United States
Primary
Concomitant
Tympanic Membrane Perforation Other Serious 10/1/2002 34 Male 185 lb 9/22/2006 United States
Primary
Concomitant
Respiratory Arrest Death 43 Female 9/22/2006 Physician United States
Primary
Secondary
Weight Increased Other Serious 1/1/2006 Male 204 lb 9/29/2006 United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 9/22/2006 47 Male 196 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 9/29/2006 46 Male 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 9/29/2006 46 Male 12/4/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2004 Female 142 lb 12/6/2006 Physician United States
Primary
Secondary
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 9/29/2006 46 Male 1/16/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Death 9/22/2006 47 Male 196 lb 1/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 10/11/2005 79 Female 128 lb 2/2/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 12/16/2004 Female 119 lb 3/2/2007 Lawyer United States
Primary
Concomitant
Treatment Noncompliance 8/7/2006 63 Male 3/7/2007 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 10/11/2005 79 Female 128 lb 3/13/2007 Physician United States
Primary
Secondary
Concomitant
Sleep Walking Hospitalization Male 3/26/2007 Lawyer United States
Primary
Concomitant
Palpitations 54 Female 196 lb 3/27/2007 Consumer United States
Primary
Concomitant
Tremor 1/1/2006 43 Female 110 lb 1/23/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/11/2006 Male 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Overdose Death Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 1/1/2006 53 Female 6/19/2007
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/1998 15 Female 6/22/2007 Consumer Australia
Primary
Concomitant
Palpitations 2/23/2007 54 Female 196 lb 6/25/2007 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2001 Female 145 lb 7/24/2007 Lawyer United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 7/11/2007 54 Female 143 lb 7/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 3/1/2006 Male 8/3/2007 Consumer United States
Primary
Concomitant
Urethral Polyp Hospitalization 60 Female 8/6/2007 Physician United States
Primary
Concomitant
Sedation Hospitalization 52 Male 8/10/2007
Primary
Secondary
Drug Tolerance Hospitalization 47 Male 8/29/2007
Primary
Secondary
Weight Increased Other Serious 1/1/2001 Female 122 lb 8/31/2007 Consumer
Primary
Concomitant
Vomiting Life Threatening 54 Male 9/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Anaphylactic Reaction 47 Male 10/5/2007 United States
Primary
Secondary
Urethral Polyp Hospitalization 7/10/2007 60 Female 10/22/2007 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 7/11/2007 54 Female 130 lb 11/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Disorder Death 9/10/2007 67 Male 10/25/2007 Physician Denmark
Primary
Secondary
Aspartate Aminotransferase Increased 8/1/2007 Male 11/8/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 41 Male 1/15/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 58 Female 1/21/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 21 Male 1/21/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 21 Male 1/21/2008 Physician United States
Primary
Secondary
Poisoning Death 53 Female 1/21/2008 United States
Primary
Secondary
Respiratory Arrest Death 21 Male 1/22/2008 Physician United States
Primary
Secondary
Multiple Drug Overdose Death 7/1/2007 24 Male 150 lb 1/29/2008 Physician Austria
Primary
Secondary
Concomitant
Respiratory Arrest Death 58 Female 2/1/2008 Physician United States
Primary
Secondary
Completed Suicide Death 21 Male 1/25/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Death 58 Female 2/13/2008 United States
Primary
Secondary
Pyrexia Hospitalization 10/30/2007 39 Female 12/10/2007 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 44 Male 3/7/2008
Primary
Secondary
Concomitant
Respiratory Disorder Death 2/7/2007 40 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Tinnitus Hospitalization 35 Male 143 lb 3/6/2008 Pharmacist United States
Primary
Concomitant
Drug Diversion Other Serious Male 4/4/2008 Consumer United States
Primary
Secondary
Drug Diversion Other Serious Female 4/4/2008 Consumer United States
Primary
Secondary
Syncope Death 4/14/2008 Other Health Professional United States
Primary
Secondary
Weight Increased Other Serious 1/1/2001 Female 168 lb 4/23/2008 Consumer
Primary
Concomitant
Drug Toxicity Death 38 Male 4/16/2008 Sweden
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2008 38 Female 5/6/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Hospitalization 10/1/2007 Female 90 lb 5/16/2008 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 12/1/2007 Male 124 lb 5/20/2008 Belgium
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/6/2008 58 Male 5/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 7/10/2007 60 Female 5/19/2008 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/6/2008 58 Male 5/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 7/11/2007 54 Female 130 lb 6/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/1/2008 56 Female 6/17/2008 United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 4/15/2008 58 Male 7/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization Male 7/31/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 5/27/2008 55 Male 216 lb 7/29/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 64 Female 121 lb 8/5/2008 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 1/1/2006 43 Female 8/18/2008 Physician United States
Primary
Secondary
Respiratory Depression Hospitalization 1/1/2006 37 Male 8/18/2008 Physician United States
Primary
Secondary
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Wound Treatment Other Serious 5/1/2004 Male 297 lb 8/21/2008 United States
Primary
Concomitant
Oedema Peripheral Other Serious 64 Female 119 lb 8/27/2008 Physician United States
Primary
Concomitant
Intentional Overdose Death 8/1/2008 Male 8/29/2008 Physician United States
Primary
Secondary
Intentional Overdose Death 8/1/2008 Male 8/29/2008 Physician United States
Primary
Secondary
Blood Alkaline Phosphatase Increased 8/18/2008 Female 9/2/2008 Physician United States
Primary
Concomitant
Vomiting Life Threatening 7/7/2008 49 Female 9/16/2008 Physician Switzerland
Primary
Concomitant
Interacting
Palpitations 56 Female 240 lb 9/24/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Male 9/24/2008 Consumer United States
Primary
Concomitant
Trismus Other Serious 54 Male 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 56 Male 9/22/2008 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 11/4/2007 14 Female 130 lb 11/14/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization Male 10/9/2008 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Intentional Overdose Death 8/1/2008 Male 11/5/2008 Physician United States
Primary
Secondary
Urinary Tract Infection Hospitalization 8/1/2008 Male 11/12/2008 Consumer Canada
Primary
Secondary
Concomitant
Adverse Drug Reaction Death 41 Male 11/5/2008 Physician United States
Primary
Secondary
Blood Alkaline Phosphatase Increased 8/18/2008 48 Female 11/20/2008 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 7/11/2007 54 Female 130 lb 12/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Accidental Overdose Death 8/20/2008 Female 149 lb 12/8/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/1/2008 46 Male 202 lb 12/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 9/8/2007 54 Female 130 lb 12/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/1/2008 46 Male 202 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 23 Female 12/22/2008 Physician United States
Primary
Secondary
Upper Limb Fracture Other Serious 1/1/2003 64 Female 150 lb 1/21/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 7/4/2006 Male 146 lb 1/23/2009 Physician
Primary
Secondary
Concomitant
Vomiting Other Serious 7/4/2006 Male 146 lb 1/28/2009 Physician
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2007 20 Male 1/22/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 7/4/2006 Male 146 lb 2/6/2009 Physician
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/4/2006 Male 146 lb 2/19/2009 Physician
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Small Cell Lung Cancer Metastatic Death 11/8/2008 Female 146 lb 2/27/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Hospitalization 23 Female 3/5/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 7/4/2006 Male 146 lb 3/16/2009 Physician
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 7/1/2002 49 Female 134 lb 2/2/2009 United States
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Hospitalization Male 4 lb 4/10/2009
Primary
Secondary
Retching Life Threatening 5/14/2008 57 Female 4/9/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/1/2007 4/20/2009 Physician Belgium
Primary
Concomitant
Adverse Drug Reaction Death Male 4/21/2009
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 3/11/2009 Female 165 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 3/29/2009 Male 5/12/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/5/2009 Female 5/8/2009 Physician United States
Primary
Concomitant
Drug Diversion Other Serious Female 6/10/2009 Consumer United States
Primary
Secondary
Drug Diversion Other Serious Male 6/10/2009 Consumer United States
Primary
Secondary
Drug Diversion Other Serious Female 6/11/2009 Consumer United States
Primary
Secondary

Drug Data